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Towards Efficient Short-Range Pair Interaction on Sunway Many-Core Architecture

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Journal of Computer Science & Technology 2021年第1期36卷 123-139页

作者： Jun-Shi chen Hong An Wen-Ting Han zeng Lin xin Liu School of Computer Science and Technology University of Science and Technology of ChinaHefei 230026China National Research Center of Parallel Computer Engineering and Technology Beijing 100080China

The short-range pair interaction consumes most of the CPU time in molecular dynamics(MD)*** inherent computation sparsity makes it challenging to achieve high-performance kernel on the emerging many-core *** this paper,we present a highly efficient short-range force kernel on the Sunway,a novel many-core architecture with many unique *** parallel efficiency of this algorithm on the Sunway many-core processor is strongly limited by the poor data locality and write *** enhance the data locality,we adopt a super cluster based neighbor list with an appropriate granularity that fits in the local memory of computing *** the absence of a low overhead locking mechanism,using data-privatization force array is a more feasible method to avoid write conflicts,but results in the large overhead of data *** adopt a dual-slice partitioning scheme for both hardware resources and computing tasks,which utilizes the on-chip data communication to reduce data reduction overhead and provide load ***,we exploit the single instruction multiple data(SIMD)parallelism and perform instruction reordering of the force kernel on this many-core *** experimental results show that the optimized force kernel obtains a performance speedup of 226x compared with the reference implementation and achieves 20%of peak flop rate on the Sunway many-core processor.

关键词： molecular dynamics sunway many-core pair interaction parallel algorithm

基于卡尔加里-剑桥指南的沙龙培训模式提升全科规培医师医患沟通技能的对照研究

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中国全科医学 2025年第1期28卷 71-76页

作者：彭涛邹川曾欣张焱沈静四川省成都市第五人民医院全科医学科 611130

背景医患沟通技能是全科医生的核心岗位胜任力之一,高水平的医患沟通能力是创建和谐医患关系的基石,有助于提高患者就医获得感和满意度。而我国全科医生沟通能力普遍偏低,有待探索出一种适应我国国情、满足我国全科医生沟通需求的医患... 详细信息

背景医患沟通技能是全科医生的核心岗位胜任力之一,高水平的医患沟通能力是创建和谐医患关系的基石,有助于提高患者就医获得感和满意度。而我国全科医生沟通能力普遍偏低,有待探索出一种适应我国国情、满足我国全科医生沟通需求的医患沟通培训模式来提高其医患沟通能力。目的探索基于卡尔加里-剑桥指南的沙龙培训模式在全科规培医师医患沟通技能培训中的应用效果,为构建适合我国国情的医患沟通培训体系提供参考依据。方法选取成都市第五人民医院2019—2020年度全科规培医师40名作为研究对象,按照随机数字表法分为沙龙组和对照组,每组20名,其中沙龙组使用基于卡尔加里-剑桥指南的沙龙培训模式进行医患沟通培训,对照组设置为空白对照,培训前、培训后1周分别对两组学员采用标准化病人(SP)模式进行接诊,使用医患沟通评价量表(SEGUE量表)进行现场观察评分,比较两组学员的医患沟通培训效果。结果最终纳入28名,其中沙龙组15名,对照组13名,培训后沙龙组规培医师SEGUE量表评分从(11.80±4.36)分提高至(18.07±4.11)分,对照组规培医师SEGUE量表评分从(12.15±4.63)分提高至(14.46±3.71)分。沙龙组培训后的SEGUE量表评分与培训前的比较,差异有统计学意义(t=3.250,P<0.001);对照组培训后的SEGUE量表评分与培训前比较,差异无统计学意义(t=2.582,P=0.624);培训后对SEGUE量表中的25个项目进行分析,沙龙组与对照组SEGUE量表评分比较,差异有统计学意义(P<0.05)。沙龙组以下5个项目结果优于对照组,准备阶段中的“建立个人信任关系”(93.3%比7.7%)、“保护患者的隐私/尊重患者选择权”(53.3%比15.4%);理解患者阶段中的“认同患者为疾病所付出的努力、改变及其遇到的困难”(33.3%比23.1%)、“表达关心,使患者感到温暖/树立信心”(100.0%比69.2%);结束问诊阶段中的“询问患者是否还有其他的问题需要探讨”(66.7%比23.1%)。结论基于卡尔加里-剑桥指南的沙龙培训模式对全科规培医师进行医患沟通技能培训可增强学员主动参加培训的兴趣和积极性,对于医患沟通能力的提升具有较好的培训效果,值得借鉴和推广。

关键词：全科医学全科医师规范化培训医患沟通沟通培训卡尔加里-剑桥指南

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一种单腔式微型隔膜泵的结构设计及流量分析

真空 2016年第6期53卷 12-14页

作者：何云鹏郅静刚臧辰鑫蔺增东北大学机械工程与自动化学院辽宁沈阳110819

针对市场的实际需求,设计研制了一台流量为200mL/min的单腔式微型隔膜泵,文章介绍了流量设计计算的基本原理和泵的结构组成,利用搭建的微型泵流量测试平台进行了测试。结果表明不同电压下隔膜泵的出气速率随电压成线性关系,所设计的微... 详细信息

针对市场的实际需求,设计研制了一台流量为200mL/min的单腔式微型隔膜泵,文章介绍了流量设计计算的基本原理和泵的结构组成,利用搭建的微型泵流量测试平台进行了测试。结果表明不同电压下隔膜泵的出气速率随电压成线性关系,所设计的微型隔膜泵流量控制稳定,可靠性较高。

关键词：微型隔膜泵气体采样抽速测试

Post-evaluation of a water pollution control plan： methodology and case study

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Frontiers of Environmental Science & Engineering 2015年第4期9卷 712-724页

作者： Lin zeng xin DONG Siyu zeng Tianzhu ZHANG Jing LI Jining chen School of Environment Tsinghua University Beijing 100084 China

China has developed more than 20 water pollution control plans for river basins （RBWPs） since 1996. However, the implementation has generally lagged. This paper proposes a three-step, post-evaluation methodology to analyze the implementation result of a RBWP and its influential factors. First, a multi-attribute evaluation method based on an index system is established to score the enforcement results of a RBWP. Indicators measure how well a RBWP has achieved its objectives, which include water quality compliance, pollution load control, project construction, financial inputs, and related management requirements. Second, an interpretive structural model is used to detect the significant factors that affect RBWP implementation. This model can effectively analyze the cause-effect chain and hierarchical relationship among variables. Five groups of factors were identified, namely, plan preparation, water resource endowment, policy, institution, and management. Both qualitative and quantitative methods are employed in the third step to evaluate the extent to which these factors have influenced the execution result of a RBWP, including pre-post contrast, scenario analysis, and correlation analysis. This research then post-evaluated the implementation of the Huai River Basin water pollution control plans （H-RBWPs） over a period of 10 years as a case study. Results showed that the implementation of the H-RBWPs was unsatisfactory during 2001–2005, although it improved during 2006–2010. The poor execution of these plans was partially caused by the underestimation of regional economic development in combination with ineffective industrial structure adjustment policies. Therefore, this case study demonstrates the feasibility and flexibility of the proposed post-evaluation methodology.

关键词： river basin water pollution control plan postplan evaluation multi-attribute comprehensive evaluation,interpretive structural model combined qualitative/quantitative method

Liver as a new target organ in Alzheimer's disease:insight from cholesterol metabolism and its role in amyloid-beta clearance

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Neural Regeneration Research 2025年第3期20卷 695-714页

作者： Beibei Wu Yuqing Liu Hongli Li Lemei Zhu Lingfeng zeng Zhen Zhang Weijun Peng Department of Integrated Traditional Chinese&Western Medicine The Second Xiangya HospitalCentral South UniversityChangshaHunan ProvinceChina Academician Workstation Changsha Medical UniversityChangshaHunan ProvinceChina Yangsheng College of Traditional Chinese Medicine Guizhou University of Traditional Chinese MedicineGuiyangGuizhou ProvinceChina Qinhuangdao Shanhaiguan Pharmaceutical Co. LtdQinhuangdaoHebei ProvinceChina National Clinical Research Center for Mental Disorder The Second Xiangya HospitalCentral South UniversityChangshaHunan ProvinceChina

Alzheimer's disease,the primary cause of dementia,is characterized by neuropathologies,such as amyloid plaques,synaptic and neuronal degeneration,and neurofibrillary *** amyloid plaques are the primary characteristic of Alzheimer's disease in the central nervous system and peripheral organs,targeting amyloid-beta clearance in the central nervous system has shown limited clinical efficacy in Alzheimer's disease *** abnormalities are commonly observed in patients with Alzheimer's *** liver is the primary peripheral organ involved in amyloid-beta metabolism,playing a crucial role in the pathophysiology of Alzheimer's ***,impaired cholesterol metabolism in the liver may exacerbate the development of Alzheimer's *** this review,we explore the underlying causes of Alzheimer's disease and elucidate the role of the liver in amyloid-beta clearance and cholesterol ***,we propose that restoring normal cholesterol metabolism in the liver could represent a promising therapeutic strategy for addressing Alzheimer's disease.

关键词： ABCA1 Alzheimer's disease amyloid-beta apolipoprotein E cholesterol metabolism liver liver X receptor low-density lipoprotein receptor-related protein 1 peripheral clearance tauroursodeoxycholic acid

Verification analysis of self-verifying automata via semi-tensor product of matrices

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The Journal of China Universities of Posts and Telecommunications 2014年第4期21卷 96-104页

作者： YAN Yong-yi chen zeng-qiang LIU Zhong-xin College of Computer and Control Engineering Nankai University College of Science Civil Aviation University of China

The semi-tensor product （STP） of matrices was used in the article, as a new matrix analysis tool, to investigate the problem of verification of self-verifying automata （SVA）. SVA is a special variant of finite automata which is essential to nondeterministic communication with a limited number of advice bits. The status, input and output symbols are expressed in vector forms, the dynamic behaviour of SVA is modelled as matrix product is STP. By such algebraic formulation, three an algebraic equation of the states and inputs, in which the necessary and sufficient conditions are presented for the verification problem, by which three algorithms are established to find out all the strings which are accepted, rejected, or unrecognized by a SVA. Testing examples show the correctness of the results.

关键词： SVA recognition power matrix approach STP matrices

Surface embedded binary Co-Cu hydroxy phosphate over surface of oxy/hydroxides for efficient nitrate reduction to ammonia

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Nano Research 2025年第1期18卷 195-207页

作者： Chun Zhu Yifei Yang Yike Jing Zhen zeng Xuesong Yi Wei Sun Fei Yang Key Laboratory of Agro-Forestry Environmental Processes and Ecological Regulation of Hainan Province School of Environmental Science and EngineeringHainan UniversityHaikou 570228China

Electrochemical nitrate reduction reaction(NO3RR)to ammonia is a promising approach to address excess Ncontamination in aqueous environment but suffers from a limited ammonia yield and selectivity due to the low concentration and sluggish *** work reports a three-dimensional porous electrode with binary Co_(2)Cu_(1)hydroxy phosphate embedded into the surface of Ni_(3)Co_(1)oxy/hydroxides(CoCu-PH@NiCo/Ni,“PH”means phosphate-hydroxide),which delivers a yield of 4.13 mg·h^(-1)·cm^(-2)with a high Faraday efficiency of 92.6%under a low nitrate concentration of 40 mM and provide an impressive *** embedded structure of the as-prepared catalyst exhibits unique metal coordination ligands and valence states different from the unitary *** electrochemical in situ infrared spectra and theoretical calculations revealed that the Co sites with the ability to dissociate water molecular to form adsorbed OH*can effectively provide the required protons for the deoxygenation and hydrogenation steps during NO3-conversion,thereby,effectively reducing the energy barrier of the key transition states in the NO3RR process to improve the intrinsic *** demonstrate that the rational design of binary components with the appropriate ability to activate water molecules as well as the threedimensional porous skeletal structure are expected to promote effectively the low-concentration nitrates conversion to ammonia.

关键词： nitrate reduction hydroxy phosphate surface embedded water dissociation active hydroxy adsorbed

Possible Collapse Mode for Slender Reinforced Concrete Plates Subjected to Blast Load

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Transactions of Tianjin University 2008年第B10期14卷 500-503页

作者： ZHANG xin 杜修力 chen Zhen zeng Fanna School of Civil Engineering Zhengzhou University Zhengzhou 450001 China ColLege of Architecture and Civil Engineering Beijing University of TechnoLogy Beijing 100022 China Henan Provincial Agency of Quality Surveillance for Construction Industry Zhengzhou 450001 China

This paper discusses the collapse mode of thin reinforced concrete (RC) plates sub-jected to blast load. To extend the well known plastic-mode method to analyze, not only perfect-plastic plates , but also RC plates, it is needed to investigate the effect of material cracking on the collapse mode because the plate might have been cracked on both upper and lower surface before the plastic-mode fully develops, creating an unexpected type of collapse mode shape. A new fail-ure mode is proposed and verified by numerical analysis in this paper. The new mode is a result of the material cracking and has an un-negligible effect on the reaction mechanism of the RC plate to the blast load.

关键词： pulse load flexural wave and reinforced concrete slab

The Influence of Seafloor Hydrothermal Activity on Major and Trace Elements of the Sediments From the South Mid-Atlantic Ridge

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Journal of Ocean University of China 2017年第5期16卷 775-780页

作者： HUANG xin chen Shuai zeng Zhigang PU Xiaoqiang HOU Qinghua Guangdong Province Key Laboratory for Coastal Ocean Variation and Disaster Prediction Technologies Guangdong Ocean University Key Laboratory of Marine Geology and Environment Institute of Oceanology Chinese Academy of Sciences Laboratory for Marine Mineral Resources Qingdao National Laboratory for Marine Science and Technology

Sediment samples obtained from the South Mid-Atlantic Ridge were analyzed for the major and trace elements by inductively coupled plasma atomic emission spectroscopy and inductively coupled plasma mass spectrometry. Results revealed that the contents of elements(e.g., Fe, Mn, Cu, Zn, V, Co) were high in samples 22V-TVG10 and 26V-TVG05 from the sites near the hydrothermal areas, and low in sample 22V-TVG14, which was collected far from the hydrothermal areas. The contents of Ca, Sr and Ba in the samples showed opposite trends. A positive correlation between the concentrations of metallic elements(Cu, Zn, Co, Ni, Pb, V) and Fe in the samples were observed. These results are consistent with chemical evolution of the dispersing hydrothermal plume.

关键词： Atlantic hydrothermal inductively metallic Sediment viscosity ocean agate Major opposite