检索结果-南通市图书馆

Outcomes of ABO-incompatible liver transplantation in end-stage liver disease patients co-infected with hepatitis B and human immunodeficiency virus

引用

World Journal of Gastroenterology 2023年第11期29卷 1745-1756页

作者： Jian-xin Tang Kang-Jun Zhang Tai-Shi Fang Rui-Hui Weng Zi-Ming Liang Xu Yan xin Jin Lin-Jie Xie xin-chen zeng Dong Zhao Department of Liver Surgery and Organ Transplantation Center The Third People's Hospital of Shenzhen(The Second Affiliated Hospital of Southern University of Science and Technology)Shenzhen 518000Guangdong ProvinceChina Department of Neurology The Third People’s Hospital of Shenzhen(The Second Affiliated Hospital of Southern University of Science and Technology)Shenzhen 518000Guangdong ProvinceChina Department of Liver Surgery and Organ Transplantation Center National Clinical Research Center for Infectious DiseaseShenzhen 518000Guangdong ProvinceChina

BACKGROUND Human immunodeficiency virus(HIV)-positive patients coinfected with hepatitis B virus(HBV)are eligible for liver transplantation(LT)in Africa and Southeast Asia,particularly ***,the outcome of HIV-HBV coinfected patients referred for ABO-incompatible LT(ABOi-LT)is *** To clarify the outcome of ABOi-LT for HIV-HBV coinfected patients with endstage liver disease(ESLD).METHODS We report on two Chinese HIV-HBV coinfected patients with ESLD who underwent A to O brain-dead donor LT and reviewed the literature on HIV-HBV coinfected patients treated with ABO-compatible *** pretransplantation HIV viral load was undetectable,with no active opportunistic *** therapy consisted of two sessions of plasmapheresis and a single dose of rituximab in two split doses,followed by an intraoperative regimen of intravenous immunoglobulin,methylprednisolone,and ***-transplant maintenance immunosuppressive agents consisted of tacrolimus and mycophenolate mofetil,and *** At the intermediate-term follow-up,patients showed undetectable HIV viral load,CD4(+)T cell counts greater than 150 cells/μL,no HBV recurrence,and stable liver function.A liver allograft biopsy showed no evidence of acute cellular *** patients survived at 36-42 mo of *** This is the first report of ABOi-LT in HIV-HBV recipients with good intermediate-term outcomes,suggesting that ABOi-LT may be feasible and safe for HIV-HBV coinfected patients with ESLD.

关键词： ABO incompatibility liver transplantation Human immunodeficiency virus Hepatitis B virus End-stage liver disease Immunosuppression

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Reconstructing the portal vein through a posterior pancreatic tunnel:New choice for portal vein thrombosis during liver transplantation

引用

World Journal of Gastrointestinal Surgery 2022年第10期14卷 1131-1140页

作者： Dong Zhao Yi-Ming Huang Zi-Ming Liang Kang-Jun Zhang Tai-Shi Fang Xu Yan xin Jin Yi Zhang Jian-xin Tang Lin-Jie Xie xin-chen zeng Department of Liver Surgery and Organ Transplantation Center The Third People’s Hospital of ShenzhenThe Second Affiliated Hospital of Southern University of Science and TechnologyNational Clinical Research Center for Infectious DiseaseShenzhen 518000Guangdong ProvinceChina

BACKGROUND Thrombectomy and anatomical anastomosis(TAA)has long been considered the optimal approach to portal vein thrombosis(PVT)in liver transplantation(LT).However,TAA and the current approach for non-physiological portal reconstructions are associated with a higher rate of complications and mortality in some *** To describe a new choice for reconstructing the portal vein through a posterior pancreatic tunnel(RPVPPT)to address cases of unresectable *** Between August 2019 and August 2021,245 adult LTs were ***-five(18.4%)patients were confirmed to have PVT before surgery,among which seven underwent PV reconstruction via the RPVPPT *** retrospectively analyzed the surgical procedure and postoperative complications of these seven recipients that underwent PV reconstruction due to *** During the procedure,PVT was found in all the seven cases with significant adhesion to the vascular wall and could not be *** portal vein proximal to the superior mesenteric vein was damaged in one case when attempting thrombolectomy,resulting in massive *** was successfully performed in all patients with a mean duration of 585 min(range 491-756 min)and mean intraoperative blood loss of 800 mL(range 500-3000 mL).Postoperative complications consisted of chylous leakage(n=3),insufficient portal venous flow to the graft(n=1),intra-abdominal hemorrhage(n=1),pulmonary infection(n=1),and perioperative death(n=1).The remaining six patients survived at 12-17 mo *** The RPVPPT technique might be a safe and effective surgical procedure during LT for complex ***,follow-up studies with large samples are still warranted due to the relatively small number of cases.

关键词： Liver transplantation Portal vein thrombosis Portal vein reconstruction Retropancreatic tunnel Computer tomography angiography Three-dimensional visualization

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Brain region-specific roles of brain-derived neurotrophic factor in social stress-induced depressive-like behavior

引用

Neural Regeneration Research 2025年第1期20卷 159-173页

作者： Man Han Deyang zeng Wei Tan xingxing chen Shuyuan Bai Qiong Wu Yushan chen Zhen Wei Yufei Mei Yan zeng Brain Science and Advanced Technology Institute Wuhan University of Science and TechnologyWuhanHubei ProvinceChina Geriatric Hospital Affiliated to Wuhan University of Science and Technology WuhanHubei ProvinceChina School of Public Health Wuhan University of Science and TechnologyWuhanHubei ProvinceChina

Brain-derived neurotrophic factor is a key factor in stress adaptation and avoidance of a social stress behavioral *** studies have shown that brain-derived neurotrophic factor expression in stressed mice is brain region–specific,particularly involving the corticolimbic system,including the ventral tegmental area,nucleus accumbens,prefrontal cortex,amygdala,and *** how brain-derived neurotrophic factor participates in stress processing in different brain regions will deepen our understanding of social stress *** this review,we discuss the expression and regulation of brain-derived neurotrophic factor in stress-sensitive brain regions closely related to the pathophysiology of *** focused on associated molecular pathways and neural circuits,with special attention to the brain-derived neurotrophic factor–tropomyosin receptor kinase B signaling pathway and the ventral tegmental area–nucleus accumbens dopamine *** determined that stress-induced alterations in brain-derived neurotrophic factor levels are likely related to the nature,severity,and duration of stress,especially in the above-mentioned brain regions of the corticolimbic ***,BDNF might be a biological indicator regulating stress-related processes in various brain regions.

关键词： amygdala chronic mild stress chronic social defeat stress corticolimbic system depression hippocampus medial prefrontal cortex nucleus accumbens social stress models ventral tegmental area

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Glucocorticoid receptor signaling in the brain and its involvement in cognitive function

引用

Neural Regeneration Research 2025年第9期20卷 2520-2537页

作者： Chonglin Su Taiqi Huang Meiyu Zhang Yanyu Zhang Yan zeng xingxing chen Brain Science and Advanced Technology Institute Hubei Province Key Laboratory of Occupational Hazard Identification and ControlSchool of MedicineWuhan University of Science and TechnologyWuhanHubei ProvinceChina

The hypothalamic-pituitary-adrenal axis regulates the secretion of glucoco rticoids in response to environmental *** the brain,a nuclear receptor transcription fa ctor,the glucocorticoid recepto r,is an important component of the hypothalamicpituitary-a d renal axis's negative feedback loop and plays a key role in regulating cognitive equilibrium and *** glucoco rticoid receptor influences cognitive processes,including glutamate neurotransmission,calcium signaling,and the activation of brain-derived neurotrophic factor-mediated pathways,through a combination of genomic and non-genomic *** interactions within the central nervous system can alter the expression and activity of the glucocorticoid receptor,there by affecting the hypothalamic-pituitary-a d renal axis and stress-related cognitive *** appropriate level of glucocorticoid receptor expression can improve cognitive function,while excessive glucocorticoid receptors or long-term exposure to glucoco rticoids may lead to cognitive *** with cognitive impairment-associated diseases,such as Alzheimer's disease,aging,depression,Parkinson's disease,Huntington's disease,stroke,and addiction,often present with dysregulation of the hypothalamic-pituitary-adrenal axis and glucocorticoid receptor *** review provides a comprehensive overview of the functions of the glucoco rticoid receptor in the hypothalamic-pituitary-a d renal axis and cognitive *** emphasizes that appropriate glucocorticoid receptor signaling fa cilitates learning and memory,while its dysregulation can lead to cognitive *** provides clues about how glucocorticoid receptor signaling can be targeted to ove rcome cognitive disability-related disorders.

关键词： brain-derived neurotrophic factor calcium signaling glucocorticoid receptor glucocorticoid glutamate transmission hypothalamic-pituitary-adrenal axis long-term potentiation neurocognitive disorders neuroplasticity stress

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Gut-brain axis as a bridge in obesity and depression:Mechanistic exploration and therapeutic prospects

引用

World Journal of Psychiatry 2025年第1期15卷 12-20页

作者： Rui-Ying Fang Xiao-Rui Pan xin-xing zeng Zheng-Zheng Li Bo-Fan chen Hai-Min zeng Jie Peng The Second Clinical Medical College The Second Affiliated HospitalJiangxi Medical CollegeNanchang UniversityNanchang 330006Jiangxi ProvinceChina

A recent study by Wang et al,published in the World Journal of Psychiatry,provided preventative and therapeutic strategies for the comorbidity of obesity and *** gut-brain axis,which acts as a two-way communication system between the gastrointestinal tract and the central nervous system,plays a pivotal role in the pathogenesis of these *** suggests that metabolic byproducts,such as short-chain fatty acids,lipopolysaccharide and bile acids,which are generated by the gut microbiota,along with neurotransmitters and inflammatory mediators within the gut-brain axis,modulate the host's metabolic processes,neuronal regulation,and immune responses through diverse *** interaction between obesity and depression via the gut-brain axis involves disruptions in the gut microbiota balance,inflammatory immune responses,and alterations in the neuroendocrine *** the gut-brain axis,for example,through a ketogenic diet,the use of probiotics,and the supplementation of antioxidants,offers new remedial approaches for obesity and *** research that explores the mechanisms of the gut-brain axis is needed to provide more evidence for clinical treatment.

关键词： Gut-brain axis Obesity Depression Gut microbiota Mechanism

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

论疲劳缺口敏感度指标q及对Garwood曲线的商榷

引用

西安交通大学学报 1980年第4期 93-100页

作者：陈新增西安交通大学金属材料及强度研究所

本文论证了疲劳缺口敏感度指标q及Garwood曲线的不确切性;提出了疲劳缺口敏感性的一些表示法.

关键词：疲劳缺口敏感度疲劳极限疲劳力学性质 Garwood 缺口敏感性

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

液压设备虚拟样机设计平台研究

引用

系统仿真学报 2004年第7期16卷 1506-1508页

作者：陈新元曾良才陈奎生周云根武汉科技大学机械自动化学院湖北武汉430081

分析虚拟样机技术在液压设备设计中应用的可行性,开发出基于SolidEdge、Ansys、Matlab、Access等功能软件,能完成元件选型、二维系统原理图和工程图、三维模型图设计、辅助装配、性能仿真、三维虚拟产品网络发布等功能的液压设备虚拟样... 详细信息

分析虚拟样机技术在液压设备设计中应用的可行性,开发出基于SolidEdge、Ansys、Matlab、Access等功能软件,能完成元件选型、二维系统原理图和工程图、三维模型图设计、辅助装配、性能仿真、三维虚拟产品网络发布等功能的液压设备虚拟样机设计平台软件,并将其应用于攀枝花钢铁集团公司液压中心柱塞式伺服液压缸试验系统设计,结果表明该平台软件能有效缩短开发周期、提高设计质量。

关键词：虚拟样机液压系统 CAD 仿真

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Janus MXene film with gradient structure for highly efficient terahertz and infrared electromagnetic absorption

引用

Nano Research 2025年第1期18卷 434-442页

作者： Shaodian Yang Weiqiang Huang Zhiqiang Lin Zibo chen Rongliang Yang Yi Jia Xuebin Liu Rui Wang Zhiping zeng Yougen Hu Huanjun chen Xuchun Gui11 State Key Laboratory of Optoelectronic Materials and Technologies School of Electronics and Information TechnologySun Yat-sen UniversityGuangzhou 510275China National Key Laboratory of Materials for Integrated Circuits Shenzhen Institute of Advanced Electronic MaterialsShenzhen Institute of Advanced TechnologyChinese Academy of SciencesShenzhen 518055China China Academy of Aerospace Science and Innovation Beijing 100176China Guangdong Province Key Laboratory of Display Material and Technology Guangzhou 510275China School of Materials Science and Engineering Sun Yat-sen UniversityGuangzhou 510275China

Electromagnetic interference (EMI) shielding inhigh-frequency range, especially the rapidly growing terahertz(THz) frequency range, attracts increasing attention due tothe potential application of terahertz in 6G wirelesscommunication, and security inspection. However, traditionalconductive EMI films typically achieve high shieldingeffectiveness through strong reflection, which may causesecondary pollution to other devices. Here, a gradientstructure strategy was proposed to constructTi_(3)C_(2)Tx/hydroxypropyl methyl cellulose (HPMC) film, in whichthe content of Ti_(3)C_(2)Tx gradually increases along the thicknessdirection, resulting in different conductivity of the two surfaces(surface-M and surface-H) for the film. The obtained gradientfilmexhibits an EMI shielding efficiency of over 48.5 dB in theTHz range (0.2-1.6 THz) at a thickness of 40 μm. Especially,as the THz waves incident from the surface-H to the film, the absorption effectiveness reaches 48.2 dB (average absorbedpower loss up to 91.4%), and the reflection effectiveness is only 0.3 dB. In additions, the gradient-film also demonstrates ahigh absorption rate of 95.5% in the infrared band (2.5-16.7 μm). Moreover, the gradient-film exhibits an excellent tensilestress and Young’s modulus value of 173.1 MPa and 2.8 GPa, respectively. Therefore, the gradient-film proposed in thiswork, with excellent electromagnetic absorption in both THz and infrared band, provides a promising candidate for the nextgenerationEMI shielding applications.

关键词： electromagnetic interference shielding Janus film terahertz MXene

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Comprehensive bibliometric analysis of pharmacotherapy for bipolar disorders:Present trends and future directions

引用

World Journal of Psychiatry 2025年第1期15卷 153-167页

作者： Bo-Fan chen Li Liu Fang-Zhen Lin Hai-Min zeng Hai-Qiang Huang Chun-Fang Zhang Cong-Cong Liu Xiang chen Jie Peng Yun-Fa Wang Zhi-Lin Wang Bin chen De-Le Liu Yun Liu Zheng-Zheng Li xin-xing zeng The Second Affiliated Hospital Jiangxi Medical CollegeNanchang UniversityNanchang 330006Jiangxi ProvinceChina The Second Clinical Medical College Jiangxi Medical CollegeNanchang UniversityNanchang 330006Jiangxi ProvinceChina Department of Rehabilitation Medicine The Second Affiliated HospitalJiangxi Medical CollegeNanchang UniversityNanchang 330006Jiangxi ProvinceChina Jiangxi Provincial People’s Hospital The First Affiliated Hospital of Nanchang Medical CollegeNanchang 330006Jiangxi ProvinceChina Department of Psychiatry Jiangxi Mental HospitalHospital of Nanchang UniversityNanchang UniversityNanchang 330029Jiangxi ProvinceChina

BACKGROUND Bipolar disorder(BD)is a severe mental illness characterized by significant mood *** drug treatment modalities are crucial for managing *** To analyze the current status and future trends of global research on BD drug treatment over the last *** The Web of Science Core Collection database spanning from 2015 to 2024 was utilized to retrieve literature related to BD drug treatment.A total of 2624 articles were *** visualization and analysis were conducted using CiteSpace,VOSviewer,Pajek,Scimago Graphica,and R-studio bibliometrix to identify RESULTS The United States,China,and the United Kingdom have made the most significant contributions to research on BD drug treatment and formed notable research collaboration *** University of Pittsburgh,Massachusetts General Hospital,and the University of Michigan have been identified as the major research institutions in this *** Journal of Affective Disorders is the most influential journal.A keyword analysis revealed research hotspots related to clinical symptoms,drug efficacy,and genetic mechanisms.A citation analysis identified the management guidelines published by Yatham et al in 2018 as the most cited *** This study provides a detailed overview of the field of BD drug treatment,highlighting key contributors,research hotspots,and future *** study findings can be employed as a reference for future research and policymaking,which may enable further development and optimization of BD pharmacotherapy.

关键词： Bipolar disorder Drug treatment Bibliometric analysis Visualization Mental disorder

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

一种移动信源追踪活动目标的方法

引用

计算机工程与应用 2010年第9期46卷 217-219页

作者：张新林陈源曾德胜罗定职业技术学院广东罗定527200

无线网络的出现使移动追踪并定位正在运动的目标变为可能,在多传感器网络中,测距定位是目标定位的一种常用手段。利用测距定位的移动追踪方法,根据移动传感器信源节点的信息及感知目标所得的测距数据,推算出目标的位置,由信源节点与目... 详细信息

无线网络的出现使移动追踪并定位正在运动的目标变为可能,在多传感器网络中,测距定位是目标定位的一种常用手段。利用测距定位的移动追踪方法,根据移动传感器信源节点的信息及感知目标所得的测距数据,推算出目标的位置,由信源节点与目标节点的位置分别确定各个信源节点的追踪方向,使移动传感器信源节点沿该方向追踪目标。但被追踪的目标本身也是移动点,再利用孤立求解的特性再次推算出目标的位置,如此循环往复,直至完成任务。通过在MATLAB环境中进行仿真的实验,表明该方法可使移动信源节点有效地追踪活动目标。

关键词：无线传感器移动信源追踪目标定位

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：