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General Psychiatry 2022年第1期35卷 67-71页

作者： Chenyu Liu xinlian Zhang Tanya T Nguyen Jinyuan Liu Tsungchin Wu Ellen Lee xin m tu Division of Biostatistics and Bioinformatics Herbert Wertheim School of Public Health and Human Longevity ScienceUC San DiegoLa JollaCaliforniaUSA Department of Psychiatry Stein Institute for Research on AgingUC San DiegoLa JollaCaliforniaUSA

SUmmARY In many statistical applications,composite variables are constructed to reduce the number of variables and improve the performances of statistical analyses of these variables,especially when some of the variables are highly *** component analysis(PCA)and factor analysis(FA)are generally used for such *** the variables are used as explanatory or independent variables in linear regression analysis,partial least squares(PLS)regression is a better *** PCA and FA,PLS creates composite variables by also taking into account the response,or dependent variable,so that they have higher correlations with the response than composites from their PCA and FA *** this report,we provide an introduction to this useful approach and illustrate it with data from a real study.

关键词： composite composites component

Tests for paired count outcomes

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General Psychiatry 2018年第4期31卷 48-53页

作者： James A Proudfoot tuo Lin Bokai Wang xin m tu Clinical and Translational Research Institute University of California San Diego Departments of Biostatistics& Computational Biology and Anesthesiology University of Rochester Department of Family medicine and Public Health University of California San Diego

Paired t-tests are widely used to compare differences in paired continuous outcomes. This test, however, does not apply to non-continuous outcomes. For binary outcomes,mcNemar's test is the de facto method for comparing differences in paired binary variables. For count or frequency outcomes, there is not much discussion in the literature. The Wilcoxon signed-rank test is often used to assess differences in paired count outcomes. However, like the mann-Whitney U test, or Wilcoxon rank-sum test for comparing two independent groups, the Wilcoxon signedrank test is generally not efficient(powerful). In this essay,we consider some alternative methods for comparing paired count outcomes and compare them with the Wilcoxon signed-rank test using monte Carlo simulations.

关键词： Tests for paired count outcomes

machine learning-driven optimization of plasma-catalytic dry reforming of methane

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Journal of Energy Chemistry 2024年第9期96卷 153-163页

作者： Yuxiang Cai Danhua mei Yanzhen Chen Annemie Bogaerts xin tu Department of Electrical Engineering and Electronics University of LiverpoolLiverpool L693GJUK Research Group PLASmANT Department of ChemistryUniversity of AntwerpUniversiteitsplein 1BE-2610 Wilrijk-AntwerpBelgium College of Electrical Engineering and Control Science Nanjing Tech UniversityNanjing 211816JiangsuChina

This study investigates the dry reformation of methane(DRm)over Ni/Al_(2)O_(3)catalysts in a dielectric barrier discharge(DBD)non-thermal plasma reactor.A novel hybrid machine learning(mL)model is developed to optimize the plasma-catalytic DRm reaction with limited experimental *** address the non-linear and complex nature of the plasma-catalytic DRm process,the hybrid mL model integrates three well-established algorithms:regression trees,support vector regression,and artificial neural networks.A genetic algorithm(GA)is then used to optimize the hyperparameters of each algorithm within the hybrid mL *** mL model achieved excellent agreement with the experimental data,demonstrating its efficacy in accurately predicting and optimizing the DRm *** model was subsequently used to investigate the impact of various operating parameters on the plasma-catalytic DRm *** found that the optimal discharge power(20 W),CO_(2)/CH_(4)molar ratio(1.5),and Ni loading(7.8 wt%)resulted in the maximum energy yield at a total flow rate of∼51 mL/***,we investigated the relative significance of each operating parameter on the performance of the plasma-catalytic DRm *** results show that the total flow rate had the greatest influence on the conversion,with a significance exceeding 35%for each output,while the Ni loading had the least impact on the overall reaction *** hybrid model demonstrates a remarkable ability to extract valuable insights from limited datasets,enabling the development and optimization of more efficient and selective plasma-catalytic chemical processes.

关键词： Plasma catalysis machine learning Process optimization Dry reforming of methane Syngas production

Sample sizes based on three popular indices of risks

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General Psychiatry 2018年第6期31卷 150-152页

作者： Hongyue Wang Bokai Wang xin m tu Jinyuan Liu Changyong Feng Department of Biostatistics and Computational Biology University of Rochester Division of Biostatistics and Bioinformatics University of California San Diego Department of Anesthesiology University of Rochester

Sample size justification is a very crucial part in the design of clinical trials. In this paper, the authors derive a new formula to calculate the sample size for a binary outcome given one of the three popular indices of risk *** sample size based on the absolute difference is the fundamental one, which can be easily used to derive sample size given the risk ratio or OR.

关键词： size sample derive indices

Assessment of the Characteristics of Demersal Fish Communities Using Species-and Trait-Based Approaches in the Coastal Habitats Along Rongcheng Bay,Shandong Peninsula,China

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Journal of Ocean University of China 2024年第3期23卷 786-796页

作者： YUAN Shunjie SUN xin tu Zhong SUN Jie WANG Xianning ZHANG Peidong Key Laboratory of mariculture(Ocean University of China) Ministry of EducationQingdao 266003China Shandong Fisheries Development and Resource Conservation Center Yantai 264003China

Biodiversity declines have motivated many studies on the relationship between species diversity and ecosystem *** this study,we described the spatial-temporal characteristics of demersal fish communities along a coastal habitat in Rongcheng Bay,Shandong Peninsula,China with both species-based and biological trait-based *** field survey was carried out monthly using traps from April to October of 2018,and divided into three seasons(spring:April and may;summer:June,July and August;autumn:September,October and November).The study area included five distinct habitats:seagrass bed,natural rocky reef,bare sand,artificial reef together with natural rocky reef,and artificial reef together with bare *** analyzed the fish communities with three taxonomic diversity indices,including Shannon-Wiener,Simpson,and Pielou Evenness,as well as four functional diversity indices,including FRic,FEve,FDiv,and FDis,based on 7 functional groups which are categorized into 27 *** results showed that there were no significant differences in taxonomic diversity indices among different habitats in the three ***,significant differences were found in the functional richness of fish communities among different habitats in three *** bed represented the highest functional richness in spring and *** study demonstrates that seagrass bed is very important in enhancing the functional diversity of fish communities in a complex *** study also indicates that the combination of taxonomic diversity and functional diversity will provide a more detailed description of the characteristics of fish communities.

关键词： complex habitat biological traits biodiversity fish communities

Ultrathin GaN Film Derived from Amorphous Ga_(2)O_(3) Film

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Journal of Wuhan University of Technology(materials Science) 2024年第4期39卷 814-818页

作者：王鹏 ZHANG Binbin LIU Xiaofei ZHANG xin tu Rong ZHANG Song 李宝文 State Key Laboratory of Advanced Technology for materials Synthesis and Processing Wuhan University of TechnologyWuhan 430070China State Key Laboratory of Silicate materials for Architectures School of Materials Science and EngineeringWuhan University of TechnologyWuhan 430070China

It remains a big challenge to synthesize two-dimensional(2D)GaN material for applications in power *** synthetic methods require complex equipment and processes and time ***,we reported a two-step route to prepare polycrystalline 2D GaN *** amorphous ultrathin Ga_(2)O_(3)film was first exfoliated from the surface of liquid *** a vapor phase reaction,2D Ga_(2)O_(3)film was then converted into 2D GaN film while maintaining the 2D *** and high-resolution transmission electron microscope(HRTEm)analysis implies the successful synthesis of wurtzite-type GaN ultrathin *** simple strategy proposed in this work will provide more opportunities for applications of GaN ultrathin film in many devices.

关键词： GaN Ga_(2)O_(3) liquid gallium

Advanced machine learning methods in psychiatry: an introduction

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General Psychiatry 2020年第2期33卷 107-110页

作者： Tsung-Chin Wu Zhirou Zhou Hongyue Wang Bokai Wang tuo Lin Changyong Feng xin m tu Department of mathematics University of California San DiegoLa JollaCaliforniaUSA Department of Biostatistics and Computational Biology University of RochesterRochesterNew YorkUSA Departments of Biostatistics and Computational Biology and Anesthesiology University of RochesterRochesterNew YorkUSA Clinical and Translational Research Institute University of California San DiegoSan DiegoCaliforniaUSA Family medicine and Public Health University of California San DiegoLa JollaCaliforniaUSA Naval Health Research Center San DiegoCaliforniaUSA

mental health questions can be tackled through machine learning(mL)*** from the two mL methods we introduced in our previous paper,we discuss two more advanced mL approaches in this paper:support vector machines and artificial neural *** illustrate how these mL methods have been employed in mental health,recent research applications in psychiatry were reported.

关键词： networks. ed. learning

有效性试验、非劣效性试验、和等效试验之间的比较（英文）

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上海精神医学 2017年第6期29卷 385-388页

作者： Bokai WANG Hongyue WANG xin m. tu Changyong FENG Department of Biostatistics and Computational Biology University of Rochester Rochester NY USA Department of Anesthesiology University of Rochester Rochester NY USA Division of Biostatistics University of California San Diego La Jolla CA USA

概述:一种新型药物或治疗的效果通常是通过临床随机对照试验获得的。然而,假设的设定对生物医学研究者来说仍然是具有挑战性的问题。在本调查中,我们讨论了有效性试验、非劣效性试验、和等效性试验。这三类试验对治疗效果均有不同的假... 详细信息

概述:一种新型药物或治疗的效果通常是通过临床随机对照试验获得的。然而,假设的设定对生物医学研究者来说仍然是具有挑战性的问题。在本调查中,我们讨论了有效性试验、非劣效性试验、和等效性试验。这三类试验对治疗效果均有不同的假设。我们比较了这些试验中的假设并提供了样本量计算公式。

关键词：随机对照试验临床显著性的界值样本量大小计算

A Note on Generalized Inverses of Distribution Function and Quantile Transformation

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Applied mathematics 2012年第12期3卷 2098-2100页

作者： Changyong Feng Hongyue Wang xin m. tu Jeanne Kowalski Department of Biostatistics & Bioinformatics Rollins School of Public Health Winship Cancer Institute Atlanta USA Department of Biostatistics and Computational Biology University of Rochester Rochester USA

In this paper we study the relations of four possible generalized inverses of a general distribution functions and their right-continuity properties. We correct a right-continuity result of the generalized inverse used in statistical literature. We also prove the validity of a new generalized inverse which is always right-continuous.

关键词： Distribution Function Quantile Function Right Continuity

An Assembly of Pyrano[3,2-b]indol-2-ones via NHC-Catalyzed[3+3]Annulation of Indolin-3-ones with Ynals

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Chinese Journal of Chemistry 2024年第13期42卷 1487-1492页

作者： Xia Wang Shulei Zhang Shao-Jie Wang Hao An Xiaolan xin Haonan Lin Zhifeng tu Shenci Lu Frontiers Science Center for Flexible Electronics(FSCFE) Shaanxi Institute of Flexible Electronics(SIFE)&Shaanxi Instituteof Biomedical Materials and Engineering(SiBME)Northwestern Polytechnical University(NPU)127 West Youyi RoadXi'anShaanxi 710072China School of Chemistry and Chemical Engineering Northwestern Polytechnical University(NPU)127 West Youyi RoadXi'anShaanxi 710072China

We report herein an unprecedented N-heterocyclic carbene-catalyzed formal[3+3]annulation of ynals with N-Ts indolin-3-ones under the oxidation condition affording the functionalized pyrano[3,2-b]*** alkynyl acylazoliums via the combination of a carbene with ynals in the presence of oxidate proved to be the important intermediates for the success of this *** method features a broad substrate scope and mild conditions,including axially chiral skeletons with suitable substitutions.

关键词： N-Heterocyclic carbene Annulation Organocatalysis Atropisomerism Carbazole Aldehydes Heterocycles Asymmetric catalysis