检索结果-南通市图书馆

Effect of bowel rehabilitative therapy on structural adaptation of remnant small intestine: animal experiment

World Journal of Gastroenterology 2001年第1期7卷 66-73页

作者： xin zhou1 Yuan xin Li2 Ning Li2 Jie Shou Li2 1Department of General Surgery, Medical School, Nanjing University, Nanjing 210093. Jiangsu Province. China2Research Institute of General Hospital. Chinese PLA General Hospital of Nanjing Military Area, Nanjing 210002. Jiangsu Province. China Research Institute of General Surgery Chinese PLA General Hospital of Nanjing Military Area 305 East Zhongshan Road Nanjing 210002 Jiangsu Province China.

AIM: To investigate the individual and the combined effects of glutamine, dietary fiber, and growth hormone on the structural adaptation of the remnant small bowel. METHODS: Forty-two adult male Sprague-Dawley rats underwent 85% mid-small bowel resection and received total parenteral nutrition (TPN) support during the first three postoperational *** the 4th postoperational day, animals were randomly assigned to receive 7 different treatments for 8 days: TPNcon group, receiving TPN and enteral 20 g x L(-1) glycine perfusion; TPN+Gln group, receiving TPN and enteral 20 g x L(-1) glutamine perfusion; ENcon group, receiving enteral nutrition (EN) fortified with 20 g x L(-1) glycine; EN+Gln group, enteral nutrition fortified with 20 g x L(-1) glutamine; EN+Fib group, enteral nutrition and 2 g x d(-1) oral soybean fiber; EN+GH group, enteral nutrition and subcutaneous growth hormone (GH) (0.3 IU) injection twice daily; and ENint group, glutamine-enriched EN, oral soybean fiber, and subcutaneous GH injection. RESULTS: Enteral glutamine perfusion during TPN increased the small intestinal villus height (jejunal villus height 250 microm +/- 29 microm in TPNcon vs 330 microm +/- 54 microm in TPN+Gln, ileal villus height 260 microm +/- 28 microm in TPNcon vs 330 microm +/- 22 microm in TPN+Gln, P11 microm in TPN+Gln,P1). 52 microg x L-(-1) in EN+Fib,1200 microg x L(-1). 96 microg x L-(-1) in EN +/- GH, vs 620 microg x L(-1).43 microg x L-(-1) in ENcon, P< 0.05),

关键词： Parenteral Nutrition, Total Adaptation, Physiological Animals Body Weight Dietary Fiber Glutamine Glycine Growth Hormone Insulin-Like Growth Factor I Intestinal Mucosa Intestine, Small Male Rats Rats, Sprague-Dawley Recovery of Function Research Support, Non-U.S. Gov't Short Bowel Syndrome

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Expression changes of activin A in the development of hepatic fibrosis

引用

World Journal of Gastroenterology 2001年第1期7卷 37-41页

作者： xin Huang1 Ding Guo Li1 Zhi Rong Wang1 Hong Shan Wei1 Ji Lin Cheng1 Yu Tao Zhan1 xin zhou1 Qin Fang Xu1 xin Li2 Han Ming Lu1 1xinhua Hospital, Shanghai Second Medical University, Shanghai 200092, China2Ninth Hospital. Shanghai Second Medical University, Shanghai 200011. China Gastroenterology Department Xinhua Hospital Shanghai Second Medical University Shanghai 200092 China.

AIM: To examine the expression of activin A, a member of the transforming growth factor (TGFbeta) superfamily, recently has been reported to be overexpressed in liver cirrhosis, in the course of carbon tetrachloride-induced rat hepatic fibrosis. METHODS: Hepatic fibrosis was induced in rats by subcutaneous injections of 40% carbon tetrachloride oily solution for a period of 1 to 7 weeks. At the end of 1, 2, 3, 4, 5, 6 and 7 weeks after carbon tetrachloride injections, the rats were killed in group (6-10 rats each time) for study. The activin A messenger RNA expression and its protein localization were assessed by semi-quantitative reverse transcription polymerase chain reaction (RT-PCR) and immunohistochemistry. RESULTS: The normal rat liver expressed activin A mRNA and protein, and its expression was transiently decreased and became undetectable after carbon tetrachloride injections for 2 or 3 weeks and then increased gradually. After injection of carbon tetrachloride for 6 and 7 weeks, activin A mRNA and protein expressions were significantly enhanced in rat liver. Compared with that of the normal rat liver. Activin A mRNA expression levels in rats receiving carbon tetrachloride injections for 6 and 7 weeks were 1.6 and 2.2 times that of those in normal rat liver respectively (0.456 +/- 0.094 vs 0.2860.0670, P1; 0.620 +/- 0.134 vs 0.286 +/- 0670, P1). Immunohistochemistry showed that activin A expressed in hepatocytes of normal liver, and its expression was decreased in rats receiving carbon tetrachloride for 2 or 3 weeks. Compared with normal liver, activin A expression distribution mode changed in fibrotic liver, being increased significantly in hepatocytes around fibrotic areas. CONCLUSION: Activin A expression was increased in late stage of hepatic fibrosis, and this may be involved in hepatic fibrosis formation in this period.

关键词： Activins Animals Carbon Tetrachloride Gene Expression Immunohistochemistry Inhibin-beta Subunits Liver Liver Cirrhosis Male Polymerase Chain Reaction RNA, Messenger Rats Rats, Sprague-Dawley Staining and Labeling

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Competition of Composition Fluctuation Modes in Weakly Segregated Salt-doped Symmetric Diblock Copolymers

引用

Chinese Journal of Polymer Science 2024年第9期42卷 1375-1385,I0008页

作者： Yuan-xin zhou Xian Kong South China Advanced Institute for Soft Matter Science and Technology School of Emergent Soft MatterSouth China University of TechnologyGuangzhou510640China Guangdong Provincial Key Laboratory of Functional and Intelligent Hybrid Materials and Devices South China University of TechnologyGuangzhou510640China

Salt-doped block copolymers have widespread applications in batteries,fuel cells,semiconductors,and various industries,where their properties crucially depend on phase separation ***,investigations into salt-doped diblock copolymers have predominantly focused on microphase separation,overlooking the segregation between ionic and polymeric *** study employs weak segregation theory to explore the interplay between phase separation dominated by the polymer-modulated mode and the salt-out-modulated mode,corresponding to microscopic and macroscopic phase separations,*** comparing diblock copolymers doped with salts to those doped with neutral solvents,we elucidate the significant role of charged species in modulating phase *** phase separation mode exhibits a transition between the polymer-modulated and salt-out-modulated modes at different *** systems doped with neutral solvents,this transition is stepwise,while in salt-ion-doped systems,it is *** a sufficiently large Flory-Huggins parameter between ions and polymers,the salt-out-modulated mode becomes dominant,promoting macrophase *** to the solvation effect of salt ions,salt-doped systems are more inclined to undergo microphase ***,we explore factors influencing the critical wavenumber of phase separation,including doping level and the Flory-Huggins parameters between two blocks and between ions and polymeric *** findings reveal that in a neutral solvent environment,these factors alter only the boundary between micro-and macro-phase separations,leaving the critical wavenumber unchanged in microphase separation ***,in a salt-doped environment,the critical wavenumber of microphase separation varies with these *** provides valuable insights into the pivotal role of electrostatics in the phase separation of salt-doped block copolymers.

关键词： Block copolymer Phase separation Field theory Salt-doped

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Activation of leukotriene B_(4)receptor 1 is a prerequisite for complement receptor 3-mediated antifungal responses of neutrophils

引用

Cellular & Molecular Immunology 2024年第3期21卷 245-259页

作者： Yan xin Sihan Xiong Linghong zhou xin Lin Institute for Immunology and School of Medicine Tsinghua University100084BeijingChina Tsinghua University-Peking University Center for Life Sciences 100084BeijingChina Department of Infectious Diseases Shanghai Key Laboratory of Infectious Diseases and Biosafety Emergency ResponseNational Medical Center for Infectious DiseasesHuashan HospitalFudan UniversityShanghai200040China

Invasive fungal infections are life-threatening,and neutrophils are vital cells of the innate immune system that defend against *** role of LTA4H-LTB_(4)-BLT1 axis in regulation of neutrophil responses to fungal infection remains poorly ***,we demonstrated that the LTA4H-LTB_(4)-BLT1 axis protects the host against Candida albicans and Aspergillus fumigatus,but not Cryptococcus neoformans infection,by regulating the antifungal activity of *** results show that deleting Lta4h or Blt1 substantially impairs the fungal-specific phagocytic capacity of ***,defective activation of the spleen tyrosine kinase(Syk)and extracellular signal-related kinase(ERK1/2)pathways in neutrophils accompanies this ***,BLT1 regulates CR3-mediated,β-1,3-glucan-induced neutrophil phagocytosis,while a physical interaction with CR3 with slight influence on its dynamics is *** findings thus demonstrate that the LTA4H-LTB_(4)-BLT1 axis is essential for the phagocytic function of neutrophils in host antifungal immune response against Candida albicans and Aspergillus fumigatus.

关键词： LTA4H BLT1 Phagocytosis Complement receptor 3 Fungi

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Experimental and numerical investigation of two blended blade and endwall configurations

引用

Chinese Journal of Aeronautics 2024年第9期37卷 150-163页

作者： Tongtong MENG xin LI Ling zhou Lucheng JI Institute for Aero Engine Tsinghua UniversityBeijing 100084China Schoolof Aerospace Engineering Bejing Institute of TechnologyBeijing 0081China

The Blended Blade and Endwall(BBEW)technique has proven to be effective in control-ling the intersection of boundary layer in corner region of the compressor *** this study,the experiment and analysis of two different BBEW designs are ***,based on a linear cas-cade with 0.7 Mach number inflow,two different configurations,BBEW 1 and BBEW 2,are well ***,according to the experimental result,control effects of these two BBEW configu-rations are validated and compared subsequently under various working *** results demonstrate a reduction in total pressure loss of 12.8%and 29%at the design point for BBEW 1 and BBEW 2,***,the BBEW technique proves effective in suppressing the development of the boundary layer and preventing corner *** by detailed numerical analysis,improvements around the corner region,especially for the boundary layer,are extracted to show the mechanisms and distinctions between the two *** results indicate that BBEW 1 significantly restrains the development of boundary layer before separation occurs,while BBEW 2 directly controls the strength and scale of the corner separation.

关键词： Aerodynamic Computational fluid dynamic Experiment Corner separation Blended Blade and Endwall(BBEW)

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Hybrid model for BOF oxygen blowing time prediction based on oxygen balance mechanism and deep neural network

引用

International Journal of Minerals,Metallurgy and Materials 2024年第1期31卷 106-117页

作者： xin Shao Qing Liu Zicheng xin Jiangshan Zhang Tao zhou Shaoshuai Li State Key Laboratory of Advanced Metallurgy University of Science and Technology BeijingBeijing 100083China Engineering Research Center of MES Technology for Iron&Steel Production Ministry of EducationBeijing 100083China Laiwu Iron and Steel Group Yinshan Section Steel Co. Ltd.Jinan 271104China

The amount of oxygen blown into the converter is one of the key parameters for the control of the converter blowing process,which directly affects the tap-to-tap time of converter. In this study, a hybrid model based on oxygen balance mechanism (OBM) and deep neural network (DNN) was established for predicting oxygen blowing time in converter. A three-step method was utilized in the hybrid model. First, the oxygen consumption volume was predicted by the OBM model and DNN model, respectively. Second, a more accurate oxygen consumption volume was obtained by integrating the OBM model and DNN model. Finally, the converter oxygen blowing time was calculated according to the oxygen consumption volume and the oxygen supply intensity of each heat. The proposed hybrid model was verified using the actual data collected from an integrated steel plant in China, and compared with multiple linear regression model, OBM model, and neural network model including extreme learning machine, back propagation neural network, and DNN. The test results indicate that the hybrid model with a network structure of 3 hidden layer layers, 32-16-8 neurons per hidden layer, and 0.1 learning rate has the best prediction accuracy and stronger generalization ability compared with other models. The predicted hit ratio of oxygen consumption volume within the error±300 m^(3)is 96.67%;determination coefficient (R^(2)) and root mean square error (RMSE) are0.6984 and 150.03 m^(3), respectively. The oxygen blow time prediction hit ratio within the error±0.6 min is 89.50%;R2and RMSE are0.9486 and 0.3592 min, respectively. As a result, the proposed model can effectively predict the oxygen consumption volume and oxygen blowing time in the converter.

关键词： basic oxygen furnace oxygen consumption oxygen blowing time oxygen balance mechanism deep neural network hybrid model

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Intelligent Diagnosis Method for Typical Co-frequency Vibration Faults of Rotating Machinery Based on SAE and Ensembled ResNet-SVM

引用

Chinese Journal of Mechanical Engineering 2024年第4期37卷 215-230页

作者： Xiancheng Zhang xin Pan Hao Zeng Haofu zhou Beijing Key Laboratoryof Health Monitoring and Self-recovery for High-end Mechanical Equipment Beijing University of Chemical TechnologyBeijing 100029China Engineering Research Center of Chemical Safety(Ministry of Education) Beijing University of Chemical TechnologyBeijing 100029China Engineering Management Department of China Three Gorges New Energy(Group)Co. Ltd.Beijing 101199China

Intelligent fault diagnosis is an important method in rotating machinery fault diagnosis and equipment health *** deal with co-frequency vibration faults,a type of typical fault in rotating machinery,this paper proposes a fault diagnosis method based on the stacked autoencoder(SAE)and ensembled ***,the time-and frequency-domain features of several co-frequency vibration faults are summarized based on the mechanism analysis and calculated using actual vibration *** realize and validate the high-precision diagnosis method of rotating equipment with co-frequency faults proposed in this study,the following three criteria are required:First,to improve the effectiveness and robustness of the ensembled model and the sliding window using data augmentation,adding noise,autoencoder(AE)and SAE methods are analyzed in terms of principle and practical ***,ResNet is used as the feature extractor for the ensembled ResNet-SVM *** extraction is carried out twice,and the extracted co-frequency fault features are more ***,the data augmentation method and ensemble ResNet-SVM are combined for fault diagnosis and compared with other *** experimental results show that the accuracy of the proposed method can exceed 99.9%.

关键词： Co-frequency vribation Data argumentation Ensembeled ResNet-SVM High precision fault diagnosis

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Epigenetic regulators as the foundation for molecular classification of colorectal cancer

引用

Cancer Biology & Medicine 2024年第7期21卷 547-552页

作者： Zhenyu Liu xin zhou Fuchou Tang School of Life Sciences Biomedical Pioneering Innovation CenterDepartment of General SurgeryThird HospitalPeking UniversityBejing 100871China Bejing Advanced Innovation Center for Genomics(ICG) Ministry of Education Key Laboratory of Cell Proliferation and DifferentiationBeijing 100871China Peking University Third Hospital Cancer Center Bejing 100191China Academy for Advanced Interdisciplinary Studies Peking UniversityBeijing 100871China

Colorectal cancer (CRC) accounts for approximately 10% of newly diagnosed cancer cases and cancer-related deaths worldwide~1. The identification of molecular subtypes of CRCs has significantly advanced treatment strat... 详细信息

关键词： cancer colorectal cases

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

An Adaptive Program Recommendation System for Multi-User Sharing Environment

引用

China Communications 2024年第6期21卷 112-128页

作者： Sun Shiyun Hu Zhengying Wei xin zhou Liang School of Communications and Information Engineering Nanjing University of Posts and TelecommunicationsNanjing 210003China

More and more accounts or devices are shared by multiple users in video applications,which makes it difficult to provide recommendation *** recommendation schemes overlook multiuser sharing scenarios,and they cannot make effective use of the mixed information generated by multi-user when exploring users’potential *** solve these problems,this paper proposes an adaptive program recommendation system for multi-user sharing ***,we first design an offline periodic identification module by building multi-user features and periodically predicting target user in future sessions,which can separate the profile of target user from mixed log ***,an online recommendation module with adaptive timevarying exploration strategy is constructed by jointly using personal information and multi-user social information provided by identification *** one hand,to learn the dynamic changes in user-interest,a time-varying linear upper confidence bound(LinUCB)based on personal information is *** the other hand,to reduce the risk of exploration,a timeinvariant LinUCB based on separated multi-user social information from one account/device is proposed to compute the quality scores of programs for each user,which is integrated into the time-varying LinUCB by cross-weighting ***,experimental results validate the efficiency of the proposed scheme.

关键词： adaptive exploitation LinUCB multiuser recommendation system

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

A reweighted damped singular spectrum analysis method for robust seismic noise suppression

引用

Petroleum Science 2024年第3期21卷 1671-1682页

作者： Wei-Lin Huang Yan-xin zhou Yang zhou Wei-Jie Liu Ji-Dong Li State Key Laboratory of Petroleum Resources and Engineering China University of Petroleum(Beijing)Beijing2249China SINOPEC Petroleum Exploration and Production Research Institute Beijing102206China SINOPEC Geophysical Research Institute Nanjing211103jiangsuChina

(Multichannel)Singular spectrum analysis is considered as one of the most effective methods for seismic incoherent noise *** utilizes the low-rank feature of seismic signal and regards the noise suppression as a low-rank reconstruction ***,in some cases the seismic geophones receive some erratic disturbances and the amplitudes are dramatically larger than other *** presence of this kind of noise,called erratic noise,makes singular spectrum analysis(SSA)reconstruction unstable and has undesirable effects on the final *** robustify the low-rank reconstruction of seismic data by a reweighted damped SSA(RD-SSA)*** incorporates the damped SSA,an improved version of SSA,into a reweighted *** damping operator is used to weaken the artificial disturbance introduced by the low-rank projection of both erratic and random *** central idea of the RD-SSA method is to iteratively approximate the observed data with the quadratic norm for the first iteration and the Tukeys bisquare norm for the rest *** RD-SSA method can suppress seismic incoherent noise and keep the reconstruction process robust to the erratic *** feasibility of RD-SSA is validated via both synthetic and field data examples.

关键词： Singular spectrum analysis Damping operator Seismic erratic noise Seismic signal processing Robust low-rank reconstruction

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：