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Clinical and Microbiological Characteristics of Patients with Complicated Intra-abdominal Infections in Intensive Care Unit

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Current Medical Science 2020年第1期40卷 104-109页

作者： Yang-mei XIONG xin rao Department of Intensive Care Unit Zhongnan Hospital of Wuhan UniversityWuhan 430071China

In order to investigate the clinical and microbiological characteristics of patients with complicated intra-abdominal infections(cIAIs)in intensive care unit(ICU),the clinical data of 612 cIAIs patients from January 2016 to December 2018 were retrospectively *** characteristics,distribution of pathogens and drug resistance were statistically *** was found that patients with community-acquired intra-abdominal infections(CA-IAIs)made up a majority of cIAIs *** positive rate of abdominal drainage fluid culture was 55.56%.Gramnegative bacteria accounted for the majority,the most commonly isolated bacteria of which were Escherichia coli(20.96%),Klebsiella pneumoniae(10.20%)and Pseudomonas aeruginosa(5.57%).The most commonly isolated gram-positive bacteria were Enterococcus(16.88%)and Methicillinresistant staphylococcus aureus(MRSA,3.90%).Enterobacter isolates showed high resistance rate to most cephalosporins and low resistance rate to piperacillin/tazobactam and *** spectrum beta-lactamase(ESBL)screen positive isolates from CA-IAIs patients showed an increasing trend in past three *** and MRSA showed high resistance rate to clindamycin,quinolone,erythromycin and tetracycline,while they showed high sensitivity rate to linezolid,tegacycline,teicoplanin and *** results indicate that isolated bacteria from abdominal drainage fluid show high resistance rates to commonly used antibiotics in ICU patients with *** curative effects on diseases should be monitored continuously when antibiotics are ***,we should always keep eyes on drug-resistant bacteria,especially when the treatment efficacy is not good.

关键词： complicated intra-abdominal infection pathogens extended spectrum beta-lactamase screen positive isolates resistance rate

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Jurassic integrative stratigraphy,biotas,and paleogeographical evolution of the Qinghai-Tibetan Plateau and its surrounding areas

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Science China Earth Sciences 2024年第4期67卷 1195-1228页

作者： Jianguo LI xin rao Lin MU Xiaohui CUI xin LI Hui LUO Peixue LIU Center for Excellence in Life and Paleoenvironment Nanjing Institute of Geology and PalaeontologyChinese Academy of SciencesNanjing 210008China Nanjing College University of Chinese Academy of SciencesNanjing 211135China

The Qinghai-Tibetan Plateau experienced a unique geological evolution during the Jurassic,driven by the termination of the Palaeotethys and the reduction of the *** Indian Plate separated from the northern margin of Gondwana and drifted northward from the Southern *** that the timing of strata serves as the basis for reconstructing geological history,the present work aimed to develop a new multiple stratigraphic and chronologic framework for the Jurassic strata of the Qinghai-Tibetan Plateau region via a synthesis of the material on lithostratigraphy,palaeontology,iso-radiometric dating,magnetostratigraphy,and other techniques with an emphasis on recent progress and *** new framework included the Jurassic System from the four major subdivisions of the plateau:the Baryan Har,Qiangtang,Lhasa-Gandise,and Southern Xizang(Himalaya).Ultimately,a more complete,refined biostratigraphic sequence was proposed,comprising the most common fossils in the plateau and those that are stratigraphically significant for the Jurassic stratigraphy,including ammonites,bivalves,brachiopods,foraminifera,radiolarians,and dinoflagellate cysts for the marine strata,and pollen and spores,and charophytes for the terrestrial *** biostratigraphic framework was correlated with the Jurassic international standard zonation of the Geological Time Scale 2020 via standard or representative species or genera of *** on this framework,we constructed a lateral correlation of the Jurassic strata between different basins of the *** palaeontologic correlation in the present work shows that the Lhasa-Gandise Block had a closer relationship with the Qiangtang Block than with the Southern Xizang Himalaya during the Jurassic ***,the Lhasa-Gandise Block and Qiangtang Block shared similar marine fauna features of the north marginal East *** contrasts the opinion suggesting that the Yarlung Zangbo Tethys was a small back-arc basin.A c

关键词： Biostratigraphy Chronostratigraphy Correlation Yarlung Zangbo suture Bangong Co-Nujiang suture Tethys

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Respiratory Support in Severely or CriticallyⅢICU Patients With COVID-19 in Wuhan,China

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Current Medical Science 2020年第4期40卷 636-641页

作者： Hong-tao HU Shen XU Jing WANG xin rao Department of Critical Care Medicine Zhongnan Hospital of Wuhan UniversityWuhan 430071China Department of Nephrology General Hospital of the Yangtze River ShippingWuhan 430010China

Summary:This case series aimed to describe the clinical characteristics of severely or critically ill patients with COVID-19 and compare the clinical characteristics of patients who received invasive respiratory support with those of patients who received noninvasive respiratory *** included all confirmed severe or critical illness cases of COVID-19 admitted to the Intensive Care Unit(ICU)of Zhongnan Hospital of Wuhan University,a COVID-19-designated hospital,from January 8 to March 12,*** were analyzed for cpidemiological,demographic,clinical,APACHE II,SOFA,radiological features and laboratory *** of all patients were followed up as of March 12,*** newly emerging virus had caused 55 confirmed severe or critical illness cases in ICU of a COVID-19-designated *** of the infected patients were men;more than half had underlying diseases,including hypertension,coronary artery disease and *** median age was 63 years *** symptoms at onset of ilness were fever,fatigue and dry ***(9.1%)hospitalized patients were presumed to have been infected in the hospital,and 4(7.3%)health care workers were infected in their *** the 55 confirmed severe or critical ilncss cases,10(18.2%)patients died during the follow-up period as of March 12 with the median follow-up period of 28 days(interquartile range 1635).Nine patients received VV-ECMO for severe respiratory failure and 4(44.4%)patients ***,28 patients received invasive respiratory support and 14(50.0%)patients *** this single-center study,55 severely or critically ill ICU patients were confirmed to have COVID-19 in Wuhan and the overall mortality was 29.1%。Totally 28(50.9%)of severely or critically ill ICU patients received invasive respiratory support and 14(50.0%)died during the follow-up period.

关键词： COVID-19 SARS-CoV-2 acute respiratory distress syndrome intensive care unit respiratory support

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不同内植物固定耻骨上下支骨折生物力学特征的比较

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中国组织工程研究 2025年第27期29卷 5757-5764页

作者：饶鑫蒋代翔鲁辉罗杨兴李盟刘定玺吴启梅刘融武汉科技大学附属普仁医院骨科湖北省武汉市430081 武汉科技大学医学院湖北省武汉市430065 武汉科技大学附属普仁医院创新与转化研究所湖北省武汉市430081 武汉科技大学机械工程学院湖北省武汉市430080 武汉刘三屋中医骨伤医院湖北省武汉市430200

背景:经皮逆向空心螺钉、微创经皮钢板广泛应用于单侧耻骨支骨折中,但存在误穿髋关节和损伤骨盆内侧滋养动脉等缺点。一种新型逆行耻骨上支髓内钉治疗骨盆前环骨折拥有透射次数少和手术时间短等优点,但目前缺乏上述3种内植物生物力学特... 详细信息

背景:经皮逆向空心螺钉、微创经皮钢板广泛应用于单侧耻骨支骨折中,但存在误穿髋关节和损伤骨盆内侧滋养动脉等缺点。一种新型逆行耻骨上支髓内钉治疗骨盆前环骨折拥有透射次数少和手术时间短等优点,但目前缺乏上述3种内植物生物力学特征的验证。目的:通过有限元分析方法,比较在不同工况下经皮逆向空心螺钉、微创经皮钢板和逆行耻骨上支髓内钉治疗耻骨上下支骨折的生物力学差异。方法:收集1名志愿者的骨盆CT数据,将数据导入mimics 20、Geomagic Wrap 2021、Soildworks 2019中,建成3种内固定治疗单侧耻骨支骨折的几何模型,分别为空心螺钉组、钢板组、髓内钉组。分别将上述模型导入Ansys 2022软件设置垂直工况、开书样工况、剪切工况进行前处理和计算,比较分析内植物的力学稳定性。结果与结论:①在垂直工况下,空心螺钉治疗单侧耻骨骨折的生物力学稳定性较钢板和髓内钉更为优秀,其内植物应力峰值最小,其余两组对比空心螺钉组峰值增加4倍以上;②在开书样工况下,钢板治疗单侧耻骨骨折有更好的生物力学稳定性,钢板组降低耻骨上支断端应力有较好表现,其他两组的应力较钢板组增加5倍以上;③在剪切工况下,髓内钉治疗单侧耻骨骨折表现出良好的生物力学稳定性,其维持骨盆位移效果最佳,其他两组骨盆位移比髓内钉组增加了25%以上;④提示不同内植物在生物力学上存在差异性:逆行经皮空心螺钉在垂直工况下内植物应力峰值最小,微创经皮钢板在开书样工况下减小耻骨上支断端应力最优,逆行耻骨上支髓内钉在剪切工况下骨盆位移最小,可以将内植物生物力学差异性与患者临床实际情况相结合,选择最优内植物治疗方式。

关键词：耻骨上下支骨折经皮逆向空心螺钉微创经皮钢板逆行耻骨上支髓内钉有限元分析生物力学

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The brackish-water bivalve Waagenoperna from the Lower Jurassic Badaowan Formation of the Junggar Basin and its palaeoenvironmental and palaeogeographic significance

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Geoscience Frontiers 2013年第1期4卷 95-103页

作者： Yanhong Pan Jingeng Sha Yaqiong Wang Xiaolin Zhang Xiaogang Yao Bo Peng xin rao State Key Laboratory of Palaeobiology and Stratigraphy Nanjing Institute of Geology and PalaeontologyChinese Academy of Sciences

The brackish-water bivalve Waagenoperna Tokuyama, 1959 is reported from the Lower Jurassic Badaowan Formation at four localities, along the southern margin and western margin of the Junggar Basin. Taphonomic features recorded in the field indicate that it occurs in autochthonous or parautochthonous assemblages. The autecology of Waagenoperna therefore yields information on the palaeoenvironment of the area. The restriction of Waagenoperna to marine and brackish-water settings suggests that the sea water once reached these areas during the Sinemurian. This paper discusses the palaeogeographic implications and suggests an ingression of the sea water from the west to the western and southern part of the Junggar Basin. Additionally, the two Waagenoperna species collected from the Haojiagou section in the Junggar Basin are taxonomically documented.

关键词： Brackish-water bivalve Waagenoperna Transgression Sinemurian Junggar Basin

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Quantitative Analysis of Flabellophyton from the Ediacaran Lantian Biota, South China: Application of Geometric Morphometrics in Precambrian Fossil Research

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Acta Geologica Sinica(English Edition) 2013年第4期87卷 905-915页

作者： WAN Bin YUAN Xunlai CHEN Zhe GUAN Chengguo PANG Ke TANG Qing rao xin State Key Laboratory of Palaeobiology and Stratigraphy Nanjing Institute of Geology and Palaeontology Chinese Academy of Sciences University of Chinese Academy of Sciences

As a more efficient quantitative method for morphological analysis, geometric morphometrics is applied to the flabellate fossils Flabellophyton including Flabellophyton lantianensis and Flabellophyton strigata from Neoproterozoic Ediacaran Lantian biota, South China. Both traditional morphometric analysis （including diverging angle, length, and width distribution） and geometric morphometric analysis [including superposition of normalized area analysis, non-metric multidimensional scaling （n-MDS）, Bray-Curtis similarity cluster analysis （CLUSTER） and analysis of similarities （ANOSIM）[ were performed. The results indicate there are great interspecific morphological differences between F. lantianensis and F. strigata, in addition to some intraspecific variations within each species. Here we preliminarily suggest that the previously defined Flabellophyton should be subdivided into 2 genera at least： one marked by the dark transverse striated structure, and the other without. This recharacterization and reclassification work still needs further careful observation and comprehensive analysis with large number of flabeilate fossils combining morphology, structure, population, and community-ecology study.

关键词： Lantian biota Flabellophyton morphological analysis geometric morphometrics

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The Portevin-Le Chatelier effect of gradient nanostructured 5182 aluminum alloy by surface mechanical attrition treatment

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Journal of Materials Science & Technology 2018年第12期34卷 2307-2315页

作者： Xiangchen Meng Bei Liu Lan Luo Yan Ding Xi-xin rao Bin Hu Yong Liu Jian Lu Key Laboratory of Lightweight and High Strength Structural Materials of Jiangxi Province Nanchang University School of Materials Science & Engineering Nanchang University China Science Lab. General Motors Research & Development Department of Mechanical and Biomedical Engineering City University of Hong Kong Centre for Advanced Structural Materials City University of Hong KongShenzhen Research Institute

Nanocrystalline surface layers and gradient nanostructure in 5182 aluminum alloy have been produced through surface mechanical attrition treatment(SMAT). The results indicate that the gradient nanostructure can not only improve the mechanical properties of 5182 Al alloy, but also has a certain effect on the Portevin-Le Chatelier(PLC) effect. The yield and ultimate tensile strength of 5182 Al alloy with SMAT are significantly improved combining with the decrease of fracture elongation compared with the as-received one. The PLC effect of 5182 Al alloy could be effectively postponed by the formation of gradient nanostructure after SMAT. It leads to the increase of critical strain of the PLC effect, more concentrated distribution of serrated strain, and increase of average stress amplitude in special strain range. The influence of grain size and gradient nanostructure on the PLC effect of 5182 Al alloy was also discussed in detail. Grain refinement could sharply increase the density of dislocations and hinder the movement of dislocations, which results in the decrease of moving speed of dislocations and the more concentrated distribution of solute atoms. The solute atoms would aggregate to form nano precipitates and further impede movement of dislocation. The stronger interaction between the dislocations and the nano precipitates is the main mechanism of postponed PLC effect.

关键词： Aluminum alloy Portevin-Le Chatelier effect Serrated yielding Surface mechanical attrition treatment Gradient nanostructure

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Speed Measurement Feasibility by Eddy Current Effect in the High-Speed MFL Testing

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Structural Durability & Health Monitoring 2023年第4期17卷 299-314页

作者： Zhaoting Liu Jianbo Wu Sha He xin rao Shiqiang Wang Shen Wang Wei Wei School of Mechanical Engineering Sichuan UniversityChengdu610065China Safety Environment Quality Surveillance and Inspection Research Institute of CNPC Chuanqing Drilling&Exploration Guanghan618300China Chengdu Xionggu Oil&Gas Technology Co. Ltd.Chengdu610000China Chengdu Institute of Special Equipment Inspection and Testing Chengdu610036China

It is known that eddy current effect has a great influence on magnetic flux leakage testing(MFL).Usually,contacttype encoder wheels are used to measure MFL testing speed to evaluate the effect and further compensate testing *** speed measurement method is complicated,and inevitable abrasion and occasional slippage will reduce the measurement *** order to solve this problem,based on eddy current effect due to the relative movement,a speed measurement method is proposed,which is contactless and *** the high-speed MFL testing,eddy current induced in the specimen will cause an obvious modification to the applied *** modified field,which is measured by Hall sensor,can be utilized to reflect the moving ***,the measurement principle is illustrated based on Faraday’s ***,dynamic finite element simulations are conducted to investigate the modified magnetic field ***,laboratory experiments are performed to validate the feasibility of the proposed *** results show that Bmz(r1)and Bmx(r2)have a linear relation with moving speed,which could be used as an alternative measurement parameter.

关键词： Magnetic flux leakage testing(MFL) speed measurement eddy current effect modified magnetic field

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<i>Biradiolites</i>from the Yigeziya Formation of the Southwestern Tarim Basin

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Open Journal of Geology 2019年第10期9卷 562-565页

作者： xin rao State Key Laboratory of Palaeobiology and Stratigraphy Nanjing Institute of Geology and Palaeontology and the Center for Excellence in Life and Paleoenvironment Chinese Academy of Sciences Nanjing China

Two Biradiolites species described from the Yigeziya Formation of the southwestern Tarim Basin are revised. The Maastrichtian Biradiolites boldjuanensis is small and pipe-like species that is usually preserved as clusters or bouquets. Although it was considered to be endemic to Central Asia, similar specimens are abundant in Maastrichtian of other Tethyan regions. Biradiolites minor specimens have no relationship with the genus Biradiolites because their ventral and posterior bands are protruding ridges and interband is depressed broad groove. This species is comparable with the Campanian-Maastrichtian eastern Arabian species Glabrobournonia arabica, by the character of smooth outer shell layer in right valve, and simple radial bands and ridges on margin of each shell flank, but it differs from the latter species in size and the shape of left valve. This study will be a supportive tool for the establishment and reconstruction of the palaeogeographic connection between Central Asia and other Tethyan regions.

关键词： Tarim Basin Cretaceous Rudist Biradiolites

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Morphological Evolution of Fe-Rich Phases in the AlSi_9Cu_3Mg_(0.19)(Fe)Alloy with the Addition of Minor Mn and Cr

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Acta Metallurgica Sinica(English Letters) 2018年第6期31卷 629-640页

作者： Zhi-Qiang Qiu Xiang-Chen Meng Qiu-Hong Yuan Xiao-Shu Zeng Xi-xin rao Yan Ding Lan Luo Yong Liu Key Laboratory of Lightweight and High Strength Structural Materials of Jiangxi Province Nanchang University Physical Science and Technology College Yichun University School of Materials Science and Engineering Nanchang University

The morphological evolution of Fe-rich phases in the Alalloy has been investigated with various contents of Fe,Mn,and *** results show that coarse Chinese script Fe-rich phases appear in the alloy with 0.6 wt%Fe combined with trace Mn,while the blocky Fe-rich phases appear combined with trace *** the coexistence of trace Mn and Cr,a large number of fine Chinese script Fe-rich phases could be visible in the low iron-bearing AlSi_9Cu_3-alloy（0.60 wt%）.At high Fe level（1.30 wt%）,numerous Fe-rich phases with hexagonal morphologies are observed with the trace Cr,while fish-bone and pentagonal morphologies of Fe-rich phases could be simultaneously observed with the addition of both Mn and *** results reveal that the trace Mn and Cr promote the morphological evolution of Fe-rich *** morphology evolution mechanism of Fe-rich phases has been discussed by using the atom radius and electronegativity differences of Fe,Mn,and Cr.

关键词： AlSi_9Cu_3Mg_(0.19)(Fe) alloy Fe-rich phase Sludge factor Microalloying Electronegativity differences

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