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地震 2024年第1期44卷 185-188页

作者：王勤彩罗钧陈翰林孟霖鑫中国地震局地震预测研究所北京100036

使用区域台网资料,采用CAP方法反演了2023年12月18日甘肃省积石山6.2级地震的震源机制解,结果显示,该地震为逆冲型地震,与GCMT、 GFZ和USGS的震源机制解基本一致。震源机制解节面Ⅱ的走向与积石山东缘断裂大致相同。

关键词： 2023年积石山6.2级地震震源机制解

Mechanical and Magnetic Properties of New(Fe,Co,Ni)–B–Si–Ta Bulk Glassy Alloys

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Acta Metallurgica Sinica(English Letters) 2017年第7期30卷 659-664页

作者： Yao-Xiang Geng xin lin Yu-xin Wang Jian-Bing Qiang Ying-Min Wang Chuang Dong School of Materials Science and Engineering Jiangsu University of Science and Technology State Key Laboratory of Solidification Processing Northwestern Polytechnical University Key Laboratory of Materials Modification (Ministry of Education) Dalian University of Technology

The alloying effects of the like-atom substitution of Ni and Co for Fe on the various properties of Fe_（70）B_（16.7）Si_（8.3）Ta_5 metallic glass are investigated in this present work. New Fe-based bulk glassy alloys, namely Fe_（60–x）Co_xNi_（10）B_（16.7）Si_（8.3）Ta_5（at.%;x = 10, 20 and 30） with critical diameters up to 1.5 mm, were made by means of copper mold casting.A new glass-forming ability indicator, viz., the enthalpy of supercooled liquid, has been introduced for assessment of the glass-forming abilities（GFAs） of these Fe-based multi-component alloys. Nano-indentation results indicate that the calculated elastic modulus and hardness of the bulk glassy alloys are lower than those of the Fe_（70）B_（16.7）Si_（8.3）Ta_5 alloy.Among these bulk glassy alloys, Fe_（70）B_（16.7）Si_（8.3）Ta_5 exhibits the large elastic modulus and hardness with values of 178 ± 1GPa and 12.9 ± 0.1 GPa, respectively. All the bulk glassy alloys exhibit good soft magnetic properties with high saturation magnetization Bs^0.75–1.04 T but low coercive force Hc^0.2–5.2 A/m.

关键词：（Fe,Co,Ni）–B–Si–Ta bulk glass alloys Glass-forming ability Mechanical property Magnetic property

数字经济赋能温州产业全面融入RCEP的发展路径研究

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全国流通经济 2024年第8期 117-120页

作者：林昕浙江安防职业技术学院浙江温州325016

2022年以来,温州以数字化改革为引领,深入实施数字经济“一号工程”升级版,创新数字经济赋能实体经济样本,助力做大做强“全省第三极”。一是区域影响力显著提升。在全国数字化发展能力五十强城市排名24位,位列中国数字经济发展百强城市... 详细信息

2022年以来,温州以数字化改革为引领,深入实施数字经济“一号工程”升级版,创新数字经济赋能实体经济样本,助力做大做强“全省第三极”。一是区域影响力显著提升。在全国数字化发展能力五十强城市排名24位,位列中国数字经济发展百强城市第27位。二是产业数字化全省领先。认定3个省级重点工业互联网平台,数量全省第一。三是改革创新力全省前列。2022年度数字经济系统建设考核全省优秀,优秀理论制度成果数量居全省第一。在数字经济大发展的背景下,温州市充分发挥沿海经济大市和对外贸易强市条件优势,抢抓RCEP(2012年由东盟发起,2020年由东盟十国及中国、日本、韩国、澳大利亚和新西兰共15个国家正式签署的自由贸易协定,以下简称RCEP)生效机遇,推动全市“5+5”产业高质量发展,与RCEP其他成员国开放合作取得明显成效。然而,由于温州市政府以及各主要行业产业对接RCEP时间尚短,目前仍存在一系列问题亟待改进提升。当下需要针对其中存在的问题进行优化改善,推动各主要行业产业对接RCEP,快速促进温州产业的发展。

关键词：数字经济产业发展 RCEP

Heterozygous CARD9 mutation favors the development of allergic bronchopulmonary aspergillosis

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Chinese Medical Journal 2023年第16期136卷 1949-1958页

作者： Xia Xu Haiwen Lu Jianxiong Li Jielin Duan Zhongwei Wang Jiawei Yang Shuyi Gu Rongguang Luo Shuo Liang Wei Tang Fengying Zhang Jingqing Hang Juan Ge xin lin Jieming Qu xinming Jia Jinfu Xu Department of Respiratory and Critical Care Medicine Shanghai Pulmonary HospitalInstitute of Respiratory MedicineSchool of MedicineTongji UniversityShanghai 200433China Department of Immunology School of Basic Medical SciencesCapital Medical UniversityBeijing 100069China Shanghai Tenth People’s Hospital Tongji University School of MedicineShanghai 200072China Department of Respiratory and Critical Care Medicine Ruijin HospitalShanghai Jiaotong University School of MedicineShanghai 200025China Department of Respiratory and Critical Care Medicine Shanghai Putuo District People’s HospitalShanghai 200060China Department of Respiratory and Critical Care Medicine Nantong HospitalShanghai UniversityNantongJiangsu 226007China Institute for Immunology Tsinghua University School of MedicineTsinghua-Peking Center for Life SciencesBeijing 100083China

Background:Previous research demonstrated that a homozygous mutation of g.136372044G>A(S12N)in caspase recruitment domain family member 9(CARD9)is critical for producing Aspergillus fumigatus-induced(Af-induced)T helper 2(T_(H)2)-mediated responses in allergic bronchopulmonary aspergillosis(ABPA).However,it remains unclear whether the CARD9^(S12N)mutation,especially the heterozygous occurrence,predisposes the host to ABPA.Methods:A total of 61 ABPA patients and 264 controls(including 156 healthy controls and 108 asthma patients)were recruited for sequencing the CARD9 locus to clarify whether patients with this heterozygous single-nucleotide polymorphisms are predisposed to the development of ABPA.A series of in vivo and in vitro experiments,such as quantitative real-time polymerase chain reaction,flow cytometry,and RNA isolation and quantification,were used to illuminate the involved mechanism of the disease.Results:The presence of the p.S12N mutation was associated with a significant risk of ABPA in ABPA patients when compared with healthy controls and asthma patients,regardless of Aspergillus sensitivity.Relative to healthy controls without relevant allergies,the mutation of p.S12N was associated with a significant risk of ABPA(OR:2.69 and 4.17 for GA and AA genotypes,P=0.003 and 0.029,respectively).Compared with patients with asthma,ABPA patients had a significantly higher heterozygous mutation(GA genotype),indicating that p.S12N might be a significant ABPA-susceptibility locus(aspergillus sensitized asthma:OR:3.02,P=0.009;aspergillus unsensitized asthma:OR:2.94,P=0.005).The mutant allele was preferentially expressed in ABPA patients with heterozygous CARD9^(S12N),which contributes to its functional alterations to facilitate Af-induced T_(H)2-mediated ABPA development.In terms of mechanism,Card9 wild-type(Card9^(WT))expression levels decreased significantly due to Af-induced decay of its messenger RNA compared to the heterozygous Card9 S12N.In addition,ABPA patients with heterozygous CARD9^(S12N)had increased

关键词： Allergic bronchopulmonary aspergillosis polymorphism Allelic expression imbalance Asthma

Influence of travel speed on microstructure and mechanical properties of wire + arc additively manufactured 2219 aluminum alloy

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Journal of Materials Science & Technology 2020年第2期37卷 143-153页

作者： Yinghui Zhou xin lin Nan Kang Weidong Huang Jiang Wang Zhennan Wang State Key Laboratory of Solidification Processing Northwestern Polytechnical UniversityXi’an 710072China Key Laboratory of Metal High Performance Additive Manufacturing and Innovative Design MIIT ChinaNorthwestern Polytechnical UniversityXi’an 710072China

Wire+arc additive manufacturing(WAAM)was preliminarily employed to fabricate the 2219 aluminum alloy.The influence of the electric arc travel speed(TS)on the macro-morphology,microstructure,and mechanical properties were investigated.The results indicated that as the electric arc TS increased,the size and the volume fraction of equiaxed grain decreased.The high arc TS during WAAM also promoted the precipitation of theθ(Al2Cu)phase.The volume fractions ofθ’’andθ’phases reached maximum values when TS is 350 and 250 mm/min,respectively.The thermal cycle facilitated the precipitation of theθ’phase.In addition,the micro-hardness and tensile strength of the alloy were analyzed,and the results indicated that samples fabricated at TS of 350 mm/min possessed finer equiaxed grain and exhibited higher ultimate tensile strength(273.5 MPa)and yield strength(182.9 MPa)compared to those fabricated at 250 mm/min.

关键词： Wire+arc additive manufacturing 2219 aluminum alloy Microstructure Mechanical properties

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薄板几何非线性弯曲分析的深度能量法

计算力学学报 2024年第3期41卷 556-563页

作者：彭林欣罗伟嫚黄钟民广西大学土木建筑工程学院南宁530004 广西大学广西防灾减灾与工程安全重点实验室工程防灾与结构安全教育部重点实验室南宁530004

发展了一种增量形式的深度能量法求解薄板几何非线性弯曲问题。根据最小势能原理和Von-Karman非线性理论,构建以薄板势能为驱动的增量式深度神经网络模型。首先用网格离散薄板求解域,通过Python读取网格数据计算Hammer积分点,并以此作... 详细信息

发展了一种增量形式的深度能量法求解薄板几何非线性弯曲问题。根据最小势能原理和Von-Karman非线性理论,构建以薄板势能为驱动的增量式深度神经网络模型。首先用网格离散薄板求解域,通过Python读取网格数据计算Hammer积分点,并以此作为训练集代入网络模型预测板的弯曲位移,再将荷载分成一系列的荷载增量,每个增量步中计算薄板势能作为神经网络的损失函数,以最小化势能为目标,结合Adam优化算法更新网络模型参数,待势能取驻值后再继续下一个荷载步的计算。本文求解了不同形状、不同边界条件下薄板的几何非线性弯曲问题,并将计算结果与文献解或有限元Abaqus解进行对比,研究表明,本文方法在求解薄板的几何非线性弯曲问题上具备有效性和准确性,且增量式的神经网络模型能够减小计算内存,有效提高计算效率和模型的稳定性。

关键词：几何非线性深度能量法增量式神经网络 Von-Karman非线性理论

维普期刊数据库博看期刊

Solidification Microstructure of Laser Additive Manufactured Ti—6Al—2Zr—2Sn—3Mo—1.5Cr—2Nb Titanium Alloy

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Journal of Materials Science & Technology 2016年第4期32卷 381-386页

作者： Qiang Zhang Jing Chen Lilin Wang Hua Tan xin lin Weidong Huang State Key Laboratory of Solidification Processing Northwestern Polytechnical University

Solidification microstructure of powder fed laser additive manufactured Ti-6Al--2Zr--2Sn--3Mo--1.5Cr--2Nb titanium alloy was investigated, The results showed that by deliberately increasing the powder feed rate, partially melted powders were retained at the top of the molten pool, which can promote heteroge- neous nucleus. Thus, each cladding layer is composed of two regions：（i） randomly orientated cellular structure region caused by partially melted powders at the top of each cladding layer; and （ii） epitaxial cellular structure region adjacent to the fusion line. Usually, randomly orientated cellular structure region was totally remelted for a wide range of process conditions. The remelting effect ensures the continuity of epitaxial growth of cellular structure and leads to the formation of columnar β grains, In order to obtain equiaxed grains the scanning velocity and powder feed rate should be carefully selected to enlarge the randomly orientated cellular structure region,

关键词： Laser additive manufacturePartially melted powdersEqoiaxed grains

High pressure floating-zone growth and property characterization of Cr-doped hexagonal YMnO_3 crystals

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Journal of Materials Science & Technology 2017年第9期33卷 1061-1066页

作者： Feng Wan Xiaojun Bai Kaikai Song Jianbang Zheng xin lin Chongde Cao Department of Applied Physics Northwestern Polytechnical University School of Mechanical Electrical & Information EngineeringShandong University (Weihai) State Key Laboratory of Solidification Processing School of Materials Science and EngineeringNorthwestern Polytechnical University

Large crystal growth of Cr-doped h-YMnO3has been investigated by using a high pressure optical floatingzone method. The size of the grown crystals is typically 60–70 mm in length and 4–5 mm in diameter. The structure of the grown crystals is analyzed by powder X-ray diffraction and scanning electron microscopy.The defects in the as-grown crystals, including low-angle grain boundary and inclusions are studied. An off-stoichiometric phenomenon is found with a slight Cr deficiency in different parts. The relationship between defects and growth conditions during crystal growth is also discussed. The magnetic properties show spin-glass phase features with weak ferromagnetic behavior below 30 K.

关键词： High pressure floating zone technique Crystal growth Cr-doped YMnO3 High vapor pressure compound

肉碱缺乏症性心肌病患儿血浆循环游离线粒体DNA定量分析及其临床意义

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中华实用儿科临床杂志 2024年第3期39卷 193-197页

作者：聂抒林欣徐阳韩燕燕吉林大学第一医院儿科长春130021

目的检测肉碱缺乏症性心肌病患儿血浆循环游离线粒体DNA(ccf-mtDNA)水平并探讨其临床意义。方法前瞻性病例对照研究。收集2017年7月至2022年6月吉林大学第一医院小儿心血管科病房收治的7例以心肌病为主要临床表现的原发性肉碱缺乏症(PCD... 详细信息

目的检测肉碱缺乏症性心肌病患儿血浆循环游离线粒体DNA(ccf-mtDNA)水平并探讨其临床意义。方法前瞻性病例对照研究。收集2017年7月至2022年6月吉林大学第一医院小儿心血管科病房收治的7例以心肌病为主要临床表现的原发性肉碱缺乏症(PCD)患儿(PCD组)、同期就诊的16例扩张型心肌病(DCM)患儿(DCM组)及50例健康体检儿童(健康对照组)血液样本,采用实时荧光定量PCR方法检测各组血浆ccf-mtDNA水平并比较其差异,分析PCD组中血浆ccf-mtDNA水平与血游离肉碱水平、心功能的相关性,并监测PCD组应用左旋肉碱治疗后ccf-mtDNA的水平变化。3组间比较采用Kruskal-Wallis检验,PCD组与健康对照组比较采用Mann-Whitney检验,PCD组内治疗前后比较采用配对Wilcoxon秩和检验,变量间相关分析采用Logistic回归分析。结果PCD组、DCM组患儿血浆ccf-mtDNA水平分别为3.69×10^(6)(1.09×10^(6)~7.26×10^(6))拷贝/L、0.99×10^(6)(0.25×10^(6)~4.10×10^(6))拷贝/L,明显高于健康对照组[0.09×10^(6)(0.01×10^(6)~0.35×10^(6))拷贝/L](H=33.34、24.69,均P0.05)。结论血浆ccf-mtDNA可能是肉碱缺乏症性心肌病的致病因素之一,其水平对此疾病的心脏病情评估具有一定的临床价值。

关键词：原发性肉碱缺乏症血浆循环游离线粒体DNA 心肌病

热态C_(5)F_(10)O/CO_(2)混合气体电击穿特性研究

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高压电器 2024年第4期60卷 10-16,23页

作者：崔兆轩林莘徐建源李磊沈阳工业大学电气工程学院沈阳110870

热态气体的临界击穿场强是评估高压断路器弧后电击穿特性的基础数据,文中研究了C_(5)F_(10)O/CO_(2)混合气体在C_(5)F_(10)O混合比例k=0~10%、压强0.1~2.0 MPa、温度300~4 000 K范围内的临界击穿场强。基于质量作用定律数学模型,得到不... 详细信息

热态气体的临界击穿场强是评估高压断路器弧后电击穿特性的基础数据,文中研究了C_(5)F_(10)O/CO_(2)混合气体在C_(5)F_(10)O混合比例k=0~10%、压强0.1~2.0 MPa、温度300~4 000 K范围内的临界击穿场强。基于质量作用定律数学模型,得到不同温度下混合气体的平衡组分,采用两项近似方法求解玻尔兹曼方程,分析混合气体的电子能量分布函数、折合电离和吸附系数,获得混合气体的临界折合击穿场强和临界击穿场强。结果表明:0.6 MPa下,温度低于3 000 K时,随着温度降低,k=0~10%混合气体的临界击穿场逐渐低于SF_(6);在温度高于3 000 K时,混合气体的临界击穿场强为SF_(6)的1.2倍以上,具有较强的绝缘能力。研究结果可为C_(5)F_(10)O/CO_(2)混合气体高压断路器弧后电击穿特性研究提供参考。

关键词： C_(5)F_(10)O/CO_(2)混合气体 SF_(6)替代气体电击穿特性临界击穿场强粒子组分玻尔兹曼方程