检索结果-南通市图书馆

Precipitation regulated soil nematode community and footprint in cropland ecosystems

Soil Ecology Letters 2023年第4期5卷 19-28页

作者： Pingting Guan Jianan Li Cao Hao Jingjing Yang Lihong Song ximei niu Ping Wang Mohammad Mahamood Donghui Wu State Environmental Protection Key Laboratory of Wetland Ecology and Vegetation Restoration School of EnvironmentNortheast Normal UniversityChangchun 130117China Key Laboratory of Vegetation Ecology Ministry of EducationNortheast Normal UniversityChangchun 130024China College of Agriculture Guizhou UniversityGuiyang 550025China Department of Biology Deanship of Educational ServicesQassim UniversityBuraydahSaudi Arabia Jilin Provincial Key Laboratory of Animal Resource Conservation and Utilization Northeast Normal UniversityChangchun 130117China Key Laboratory of Wetland Ecology and Environment Northeast Institute of Geography and AgroecologyChinese Academy of SciencesChangchun 130102China

●Nematode abundance and footprint show unimodal patterns with precipitation levels.●MAP governed nematode diversity along the precipitation gradient of agroecosystem.●Soil pH determined nematode abundance and footprint in low precipitation *** plays a crucial role in global biodiversity change across terrestrial *** is proven to affect soil organism diversity in natural ***,how precipitation change affects the function of the soil nematode community remains unclear in cropland ***,we tested soil nematode communities from different precipitation sites(300 mm to 900 mm)of the agricultural *** abundance of total nematodes,fungivores,and plant parasites,together with the footprint of fungivores was significantly affected by mean annual precipitation(MAP)in cropland *** parasites diversity and footprint showed negative relationships with *** random forest suggested plant parasite footprint was the most responsive to *** structural equation model revealed that MAP affected nematode abundance and footprint indirectly via soil pH;nematode diversity was affected by MAP *** conclude that precipitation could act as the main selection stress for nematode diversity among the large gradient of agricultural ***,the soil pH may act as a stress factor in determining nematode community and carbon flow in the soil food *** study emphasized that using nematode value by trophic group would provide a deep understanding of nematode response to precipitation in cropland ecosystems.

关键词： soil nematode community nematode carbon flux the Northeast China Transect agricultural ecosystem precipitation

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Applications of in-situ solid-state nuclear magnetic resonance in methanol to olefins reaction

引用

Science China Chemistry 2025年第1期68卷 134-151页

作者： Jing niu Shutao Xu Yingxu Wei Zhongmin Liu National Engineering Research Center of Lower-Carbon Catalysis Technology Dalian Institute of Chemical PhysicsChinese Academy of Sciences State Key Laboratory of Catalysis Dalian Institute of Chemical Physics Chinese Academy of Sciences University of Chinese Academy of Sciences

The methanol-to-olefins（MTO） reaction offers an alternative pathway for the production of low-carbon olefins from non-oil feedstocks. Fundamental research has been impeded by a lack of comprehensive understanding of its underlying mechanism,despite the significant progress made in industry. In-situ solid-state nuclear magnetic resonance（ss NMR） spectroscopy has emerged as a pivotal tool, offering crucial insights into key species under real-time operando conditions. Furthermore, the host–guest interaction between zeolites or surface species residing on zeolites and the reactant/active intermediates is revealed by the combination of in-situ13C MAS NMR and 2D correlation spectroscopy. Moreover, recent technological advancements in hyperpolarization（HP） methods, including HP129Xe NMR and dynamic nuclear polarization（DNP）, have significantly improved the sensitivity of ss NMR, enabling detailed structural and kinetic analysis as well as the detection of trace species. In this feature article, we summarized recent advancements in（in-situ） ss NMR spectroscopy applied to MTO reaction processes,encompassing mechanistic investigations at various stages and the intricate host–guest interactions. These theoretical insights into the dynamic evolution of MTO reactions lay a solid foundation for the optimization of catalytic processes and the development of efficient catalysts, thereby advancing the techniques towards more sustainable and economical production route for olefins.

关键词： MTO zeolites in-situ ssNMR reactive intermediates reaction mechanism

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Ubiquitin-specific protease 1 facilitates tumor immune escape from natural killer cells and predicts the prognosis in small cell lung cancer

引用

Oncology Research 2025年第1期33卷 213-224页

作者： SHIQIN JIANG YICHUN TANG FENG MA YUCHUN niu LEI SUN Department of Clinical Pharmacy Shenzhen Hospital of Integrated Traditional Chinese and Western MedicineShenzhen518104China Department of Pathology Zhujiang HospitalSouthern Medical UniversityGuangzhou510280China Department of Radiation Oncology The First People’s Hospital of FoshanFoshan528000China Department of Oncology The First Affiliated Hospital of Jinan UniversityJinan UniversityGuangzhou510630China Department of Oncology The First Dongguan Affiliated HospitalGuangdong Medical UniversityDongguan523721China

Objective:Small cell lung cancer(SCLC)is commonly recognized as the most fatal lung cancer *** substantial advances in immune checkpoint blockade therapies for treating solid cancers,their benefits are limited to a minority of patients with *** the present study,novel indicators for predicting the outcomes and molecular targets for SCLC treatment were ***:We conducted bioinformatics analysis to identify the key genes associated with tumor-infiltrating lymphocytes in *** functional role of the key gene identified in SCLC was determined both in vitro and in ***:A significant correlation was observed between patient survival and CD56dim natural killer(NK)cell ***,we noted that the hub gene ubiquitin-specific protease 1(USP1)is closely correlated with both CD56dim NK cells and overall survival in *** analysis revealed that USP1 is upregulated in *** addition,gene set enrichment analysis revealed that USP1 overexpression hinders NK cell-mediated immune *** co-cultivating NK-92 cells with SCLC cells,we demonstrated that NK cell cytotoxicity against SCLC could be improved either via USP1 knock-down or pharmacological ***,using a nude-mice xenograft tumor model,we noted that USP1 inhibition effectively suppressed tumor proliferation and increased the expression of NK cell-associated ***:Our study findings highlight the importance of NK cells in regulating ***1 overexpression can inhibit NK cell-mediated immunity;therefore,USP1 may serve not only as a prognostic biomarker but also as a potential molecular target of SCLC therapy.

关键词： Ubiquitin-specific protease 1(USP1) Natural killer(NK)cell Small cell lung cancer(SCLC) Prognosis Immune escape

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

甘肃省汛期小时降水的变化特征

引用

干旱气象 2018年第4期36卷 610-616页

作者：王胜郭海瑛牛喜梅中国气象局兰州干旱气象研究所甘肃省干旱气候变化与减灾重点实验室中国气象局干旱气候变化与减灾重点实验室甘肃兰州730020 甘肃省庆阳市气象局甘肃庆阳745000 甘肃省气象服务中心甘肃兰州730020

利用甘肃省71个国家气象站1975—2016年汛期(5—9月)逐小时降水量数据,采用线性趋势分析、空间插值等方法,对比分析了甘肃省内不同气候区(干旱区、半干旱区和半湿润区)逐时降水量时空分布特征,揭示了其变化规律。结果表明:(1)全省小时... 详细信息

利用甘肃省71个国家气象站1975—2016年汛期(5—9月)逐小时降水量数据,采用线性趋势分析、空间插值等方法,对比分析了甘肃省内不同气候区(干旱区、半干旱区和半湿润区)逐时降水量时空分布特征,揭示了其变化规律。结果表明:(1)全省小时降水比率(某小时降水量占日降水量的百分比)和降水频率一日内各时次分布不均匀,其中降水比率分布不均匀最明显的区域在干旱区,而降水频率分布不均匀最明显的区域在半湿润区。(2)全省小时降水比率低值集中在11:00—15:00,高值出现在20:00前后,主要在18:00—23:00;全省小时降水频率低值集中在12:00—17:00,高值主要在22:00至次日11:00。(3)小时降水比率的分布在3个不同气候区的差异不大;但小时降水频率半干旱区和半湿润区较大,数值也较为接近,而干旱区最小。甘肃省小时降水比率和降水频率均不存在明显的线性变化趋势。(4)全省午后降水的不稳定性要大于午前,5—8月午前降水量在一日中所占的比例小,而9月午前降水量大于午后降水量。(5)干旱区的小时降水比率对相应时次降水量的大小起主导作用,降水频率的作用次之;而半湿润区的降水比率和降水频率共同影响小时降水量。

关键词：甘肃逐小时降水量降水比率降水频率

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Weak KAM theory for two classes of almost periodic Hamiltonian systems

引用

Science China Mathematics 2025年

作者： Xun niu Kaizhi Wang Yong Li School of Mathematics and Statistics Center for Mathematics and Interdisciplinary SciencesNortheast Normal University School of Mathematical Sciences Shanghai Frontier Science Center of Modern Analysis (CMA-Shanghai)Shanghai Jiao Tong University Institute of Mathematics Jilin University

The purpose of this paper is to investigate the dynamics of Bohr almost periodic and Levitan almost periodic Hamiltonian systems via the weak KAM theory. We obtain minimal measures and weak KAM solutions in both cases. The weak KAM solution is a weak solution to the Hamilton-Jacobi equation, which formally transforms the original Hamiltonian systems into an integrable one. Consequently, we get the existence of an invariant torus in the aforementioned weak sense.

关键词：

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

C-C motif chemokine ligand 2/C-C motif chemokine receptor 2 pathway as a therapeutic target and regulatory mechanism for spinal cord injury

引用

Neural Regeneration Research 2025年第8期20卷 2231-2244页

作者： Xiangzi Wang Xiaofei niu Yingkai Wang Yang Liu Cheng Yang Xuyi Chen Zhongquan Qi School of Medicine Guangxi UniversityNanningGuangxi Zhuang Autonomous RegionChina Graduate School of Tianjin University of Traditional Chinese Medicine TianjinChina Characteristic Medical Center of People’s Armed Police Forces TianjinChina Fujian Maternity and Child Health Hospital FuzhouFujian ProvinceChina

Spinal cord injury involves non-reversible damage to the central nervous system that is characterized by limited regenerative capacity and secondary inflammatory *** expression of the C-C motif chemokine ligand 2/C-C motif chemokine receptor 2 axis exhibits significant differences before and after *** studies have revealed that the C-C motif chemokine ligand 2/C-C motif chemokine receptor 2 axis is closely associated with secondary inflammatory responses and the recruitment of immune cells following spinal cord injury,suggesting that this axis is a novel target and regulatory control point for *** review comprehensively examines the therapeutic strategies targeting the C-C motif chemokine ligand 2/C-C motif chemokine receptor 2 axis,along with the regenerative and repair mechanisms linking the axis to spinal cord ***,we summarize the upstream and downstream inflammatory signaling pathways associated with spinal cord injury and the C-C motif chemokine ligand 2/C-C motif chemokine receptor 2 *** review primarily elaborates on therapeutic strategies that target the C-C motif chemokine ligand 2/C-C motif chemokine receptor 2 axis and the latest progress of research on antagonistic drugs,along with the approaches used to exploit new therapeutic targets within the C-C motif chemokine ligand 2/C-C motif chemokine receptor 2 axis and the development of targeted ***,there are presently no clinical studies relating to spinal cord injury that are focusing on the C-C motif chemokine ligand 2/C-C motif chemokine receptor 2 *** review aims to provide new ideas and therapeutic strategies for the future treatment of spinal cord injury.

关键词： apoptosis C-C motif chemokine ligand 2/C-C motif chemokine receptor 2 pathway C-C motif chemokine receptor 2 antagonists chemokine ligand 2 chemokine receptor 2 inflammation macrophage microglia spinal cord injury therapeutic method

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Liposomes as versatile agents for the management of traumatic and nontraumatic central nervous system disorders:drug stability,targeting efficiency,and safety

引用

Neural Regeneration Research 2025年第7期20卷 1883-1899页

作者： Mingyu Zhang Chunyu Xiang Renrui niu Xiaodong He Wenqi Luo Wanguo Liu Rui Gu Department of Orthopedic Surgery China-Japan Union Hospital of Jilin UniversityChangchunJilin ProvinceChina

Various nanoparticle-based drug delivery systems for the treatment of neurological disorders have been widely ***,their inability to cross the blood–brain barrier hampers the clinical translation of these therapeutic *** are nanoparticles composed of lipid bilayers,which can effectively encapsulate drugs and improve drug delivery across the blood–brain barrier and into brain tissue through their targeting and ***,they can potentially treat traumatic and nontraumatic central nervous system *** this review,we outlined the common properties and preparation methods of liposomes,including thin-film hydration,reverse-phase evaporation,solvent injection techniques,detergent removal methods,and microfluidics ***,we comprehensively discussed the current applications of liposomes in central nervous system diseases,such as Alzheimer's disease,Parkinson's disease,Huntington's disease,amyotrophic lateral sclerosis,traumatic brain injury,spinal cord injury,and brain *** studies related to liposomes are still in the laboratory stage and have not yet entered clinical ***,their application as drug delivery systems in clinical practice faces challenges such as drug stability,targeting efficiency,and ***,we proposed development strategies related to liposomes to further promote their development in neurological disease research.

关键词： Alzheimer's disease amyotrophic lateral sclerosis brain tumors central nervous system Huntington's disease liposome drug delivery neurological disorders Parkinson's disease spinal cord injury traumatic brain injury

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Bidirectional regulation of the brain-gut-microbiota axis following traumatic brain injury

引用

Neural Regeneration Research 2025年第8期20卷 2153-2168页

作者： Xinyu You Lin niu Jiafeng Fu Shining Ge Jiangwei Shi Yanjun Zhang Pengwei Zhuang National Key Laboratory of Chinese Medicine Modernization Tianjin University of Traditional Chinese MedicineTianjinChina Haihe Laboratory of Modern Chinese Medicine Tianjin University of Traditional Chinese MedicineTianjinChina First Teaching Hospital of Tianjin University of Traditional Chinese Medicine TianjinChina National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion TianjinChina

Traumatic brain injury is a prevalent disorder of the central nervous *** addition to primary brain parenchymal damage,the enduring biological consequences of traumatic brain injury pose long-term risks for patients with traumatic brain injury;however,the underlying pathogenesis remains unclear,and effective intervention methods are *** dysfunction is a significant consequence of traumatic brain *** the most densely innervated peripheral tissue in the body,the gut possesses multiple pathways for the establishment of a bidirectional“brain-gut axis”with the central nervous *** gut harbors a vast microbial community,and alterations of the gut niche contribute to the progression of traumatic brain injury and its unfavorable prognosis through neuronal,hormonal,and immune pathways.A comprehensive understanding of microbiota-mediated peripheral neuroimmunomodulation mechanisms is needed to enhance treatment strategies for traumatic brain injury and its associated *** comprehensively reviewed alterations in the gut microecological environment following traumatic brain injury,with a specific focus on the complex biological processes of peripheral nerves,immunity,and microbes triggered by traumatic brain injury,encompassing autonomic dysfunction,neuroendocrine disturbances,peripheral immunosuppression,increased intestinal barrier permeability,compromised responses of sensory nerves to microorganisms,and potential effector nuclei in the central nervous system influenced by gut ***,we reviewed the mechanisms underlying secondary biological injury and the dynamic pathological responses that occur following injury to enhance our current understanding of how peripheral pathways impact the outcome of patients with traumatic brain *** review aimed to propose a conceptual model for future risk assessment of central nervous system-related diseases while elucidating novel insights into the bidirectional effec

关键词： traumatic brain injury brain-gut-microbiome axis gut microbiota neuroimmune immunosuppression host defense vagal afferents bacterial infection dorsal root ganglia nociception neural circuitry

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Microstructure Evolution and Mechanism of Strength Development of Fly Ash Paste

引用

Journal of Wuhan University of Technology(Materials Science) 2025年第1期40卷 152-163页

作者： MA Shuzhao WU Shunchuan HUANG Mingqing CHENG Haiyong JIANG Guanzhao niu Yonghui LIU Zemin SUN Wei Faculty of Land Resources Engineering Kunming University of Science and TechnologyKunming 650093China Zijin School of Ge-ology and Mining Fuzhou UniversityFuzhou 350108China

Three types of activators such as sodium hydroxide,calcium oxide and triethanolamine(TEA)are used to establish different activation environments to address the problems associated with the process of activating fly ash *** conducted mechanical tests and numerical simulations to understand the evolution of microstructure,and used environmental scanning electron microscopy(ESEM)and energy dispersive spectroscopy(EDS)techniques to analyze the microenvironments of the *** mechanical properties of fly ash paste under different activation conditions and the changes in the microstructure and composition were *** results revealed that under conditions of low NaOH content(1%-3%),the strength of the sample increased *** the content exceeded 4%,the rate of increase in strength *** on the results,the optimal NaOH content was identified,which was about 4%.A good activation effect,especially for short-term activation(3-7 d),was achieved using TEA under high doping *** activation effect was poor for long-term strength after 28 *** CaO content did not significantly affect the degree of activation *** maximum effect was exerted when the content of CaO was 2%.The virtual cement and concrete testing laboratory(VCCTL)was used to simulate the hydration process,and the results revealed that the use of the three types of activators accelerated the formation of Ca(OH)_(2) in the *** activators also corroded the surface of the fly ash particles,resulting in a pozzolanic *** active substances in fly ash were released efficiently,and hydration was *** pores were filled with hydration products,and the microstructure changed to form a new frame of paste filling that helped improve the strength of fly ash paste.

关键词： paste filling fly ash activator unconfined compressive strength microstructure hydration simulation

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

肿瘤相关成纤维细胞在乳腺癌中的作用

引用

国际肿瘤学杂志 2021年第10期48卷 614-617页

作者：王爱玲牛喜梅黄国福冷晓玲新疆医科大学第五附属医院肿瘤科乌鲁木齐830000 新疆医科大学附属肿瘤医院超声科乌鲁木齐830011

乳腺癌细胞与肿瘤微环境之间的相互作用在乳腺癌发生发展过程中发挥至关重要的作用。肿瘤相关成纤维细胞是肿瘤微环境中含量丰富的异质性基质细胞,通过分泌多种细胞因子、生长因子和趋化因子参与肿瘤血管的生成、治疗抵抗和远处转移,将... 详细信息

乳腺癌细胞与肿瘤微环境之间的相互作用在乳腺癌发生发展过程中发挥至关重要的作用。肿瘤相关成纤维细胞是肿瘤微环境中含量丰富的异质性基质细胞,通过分泌多种细胞因子、生长因子和趋化因子参与肿瘤血管的生成、治疗抵抗和远处转移,将其作为乳腺癌的靶向治疗及临床预后的生物标志物具有巨大潜力,也可为乳腺癌辅助治疗提供新思路。

关键词：乳腺肿瘤癌相关成纤维细胞肿瘤微环境

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：