检索结果-南通市图书馆

Aryl hydrocarbon receptor nuclear translocator 2 as a prognostic biomarker and immunotherapeutic indicator for clear cell renal cell carcinoma

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

BIOCELL 2023年第11期47卷 2397-2408页

作者： RENLONG ZHOU SHUANG LI xilin XIAO Department of Public Health Laboratory Sciences University of South ChinaHengyang421001China Department of Blood Transfusion Shenzhen Longhua District Central HospitalShenzhen518000China Bioinformatics R&D Department Hangzhou Mugu Technology Co.Ltd.Hangzhou310000China

Background:In many cancer types,aryl hydrocarbon receptor nuclear translocator 2(ARNT2)has been found to be associated with tumor cell proliferation and ***,the role of ARNT2 in clear cell renal cell carcinoma(ccRCC)has not been completely *** this study,the potential role of ARNT2 in ccRCC development was ***:A pan-cancer dataset(TCGA-TARGET-GTEx)was accessed from UCSC Xena Data ***2 expression in normal and tumor samples was *** Cox regression was performed to evaluate the prognostic value of *** sample gene set enrichment analysis(ssGSEA)was used to estimate the enrichment of functional pathways and gene *** and ESTIMATE methods evaluated the immune *** ARNT2 expression was determined in ccRCC tissue and cell lines using RT-qPCR and Western ***:ARNT2 expression was significantly dysregulated in 23 out of 30 cancer ***-cancer data revealed a strong correlation between ARNT2 expression and immune modulators,immune cell infiltration,and genomic *** ccRCC patients,the low-ARNT2 expression group had higher immune infiltration,CD8 T cells,and programmed cell death ligand 1 expression,as well as higher enrichment score of immunotherapeutic predictors than those in the high-ARNT2 expression ***-ARNT2 expression group was more responsive to ***,low ARNT2 expression was observed in ccRCC tissue and cell ***:Dysregulated ARNT2 expression is involved in cancer development and the modulation of the immune ***2 can be potentially used as a prognostic indicator and an immunotherapeutic indicator for ccRCC.

关键词： Pan-cancer Clear cell renal cell carcinoma Aryl hydrocarbon receptor nuclear translocator 2 Immune microenvironment Immunotherapy

Analysis of China Natural Gas Industry Prosperity Index for the 4th Quarter of 2022

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

China Oil & Gas 2022年第6期29卷 59-62页

作者： Shen xilin Liu fang Southwest Petroleum University China Natural Gas Industry Prosperity Index Research CenterSWPU

The statistics of the China Natural Gas Industry Prosperity Index showed that the China Natural Gas Industry Prosperity Index was 245.75 in the 4th quarter of 2022,up 3.8%from the 3rd quarter,a stably prosperous state in the short term and a very prosperous state in the medium to long term;the prosperity index of natural gas production companies was 332.75 in the 4th quarter of 2022,up 4.1%from the 3rd quarter,an increasingly prosperous state in the short term and a very prosperous state in the medium to long term;the prosperity index of natural gas sales companies was 168.87 in the 4th quarter of 2022,up 2.6%from the 3rd quarter,a recovery in the short term and a prosperous state in the medium to long term;the prosperity trend index of the natural gas industry in the coming year for the 4th quarter of 2022 was 432.56,up 3.5%from the 3rd quarter,a very prosperous state,indicating that natural gas industry experts are optimistic about the natural gas industry’s prosperity trend in the coming year(Fig.1 and Table 1).

关键词： companies Prosper quarter

鄂西走马地区大塘坡组顶部泥岩碎屑锆石LA-ICP-MS U-Pb年龄及其地质意义

在线全文

学校读者我要写书评

暂无评论

沉积与特提斯地质 2019年第1期39卷 22-31页

作者：李明龙田景春方喜林郑德顺许克元陈林曹文胜赵军冉中夏成都理工大学沉积地质研究院四川成都610059 湖北省地质局第二地质大队湖北恩施445000 河南理工大学资源环境学院河南焦作454000

地球在新元古代经历了Rodinia超大陆的聚合和解体,并发生了Sturtian和Marinoan两期全球规模的冰川事件。华南地区南华系古城组和南沱组冰碛岩分别对应Sturtian冰期和Marinoan冰期沉积记录,大塘坡组属于其间冰期沉积。对鄂西走马地区大... 详细信息

地球在新元古代经历了Rodinia超大陆的聚合和解体,并发生了Sturtian和Marinoan两期全球规模的冰川事件。华南地区南华系古城组和南沱组冰碛岩分别对应Sturtian冰期和Marinoan冰期沉积记录,大塘坡组属于其间冰期沉积。对鄂西走马地区大塘坡组顶部泥岩中的碎屑锆石进行了LA-ICP-MS U-Pb定年,锆石具有高Th/U比值(0.47～1.69),并显示明显的振荡环带,为岩浆成因;62颗锆石的62个数据点分析,获得的60个谐和年龄分布在651～2435Ma,主要峰值为～794Ma。最年轻单颗锆石U-Pb年龄651±7.7Ma,结合前人研究认为华南地区Marinoan冰期启动时间应晚于651Ma;碎屑锆石为亲扬子型,可能来自鄂中古陆和扬子北缘;分布最集中的751～851Ma年龄段内～850Ma峰值记录了扬子地台与华夏褶皱带碰撞拼合事件,而～820Ma、～800Ma、～760Ma等峰值则揭示了与Rodinia超大陆解体有关的幕式岩浆活动。

关键词： LA-ICP-MS U-Pb 定年碎屑锆石 Marinoan冰期 Rodinia超大陆大塘坡组走马地区

A fabrication method for adaptive dielectric gradient insulating components

在线全文

学校读者我要写书评

暂无评论

High Voltage 2023年第1期8卷 59-69页

作者： Zikui Shen Zhidong Jia Yanpeng Hao Zhenyu Xin xilin Wang School of Electric Power Engineering South China University of TechnologyGuangzhouChina Shenzhen International Graduate School(SIGS) Tsinghua UniversityShenzhenChina

Dielectric gradient components have advantages in electric field mitigation and insulation *** this paper,we propose a fabrication method for adaptive dielectric gradient components using in situ AC electric field,including the mechanism and the corresponding operational procedures for industrial *** on the electric polarisation and self-assembly effect of the filler particles in the liquid matrix,the chainlike structure in the high field strength region is constructed to enhance the local permittivity and mitigate the maximum of the spatial electric *** dielectric gradient basin insulator is prepared by this method,and its flashover voltage is increased by 12.8%compared with that of a homogeneous dielectric basin insulator,and the improvement is 20.8%when metal particles are present on the *** more non-uniform the initial electric field is,the greater the improvement in flashover *** method is expected to promote the industrial application of dielectric gradient insulating components.

关键词： dielectric gradient method

Large eddy simulation of a 3-D spatially developing turbulent round jet

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Science China(Technological Sciences) 2011年第11期54卷 2916-2923页

作者： ZHANG HuiQiang RONG Yi WANG Bing WANG xilin School of Aerospace Tsinghua University Beijing 100084 China

A three-dimensional large eddy simulation （LES） of a spatially developing round jet is carried out in cylindrical coordinates using a dynamic subgrid model with strong inflow instability. Evolutions of large-scale vortex structures represented by tangential vortices are obtained and compared with flow visualization. Also presented are three-dimensional spatial evolutions of coherent structure, which are of quasi two-dimensional Kelvin-Helmholtz instability and vortex rings as well as breaking up of the vortex rings with fully three-dimensional characteristics. Predicted results of mean velocity and turbulent intensity agree well with experiments. They are also compared with the results predicted by LES using standard Smagorinsky model and show good self-similarity. Turbulence spectrum of the predicted velocity shows the -5/3 decay for higher wave number, as expected for turbulent round jet flows. In addition, fl-test and y-test are carded out for the instantaneous velocity, showing that the present LES method can successfully predict the hierarchical structure of round jet.

关键词： large eddy simulation round jet spatially developing flow large-scale structure hierarchical structure

Multi-parametric geochemical survey on evaluation of hydrocarbon potential of trap structure in a desert area: A case of TD-2 structure in the Tarim Basin, China

在线全文

学校读者我要写书评

暂无评论

Chinese Journal Of Geochemistry 2011年第1期30卷 99-106页

作者： LI Zhiming ZHANG Changjiang SONG xilin Institute of Experimental Petroleum Geology RIPEP SINOPEC Wuxi 214151 China Department of Integrative Geophysical and Geochemical Exploration BGP Zhuozhou 072751 China

TD-2 structure is located in the eastern part of the Central Uplift zone of the Tarim Basin, China. It is a basement-uplift anticline-type structure confirmed by seismic and gravity prospecting, and it is expected to have good potential for oil and gas according to the analysis of regional geological evolution history. But further exploration such as drilling is suspended because of lacking direct geochemical information. Therefore, multi-parametric geochemical surveys, such as free hydrocarbons (C1-C5), acid hydrocarbons (C1-C5) and ?C, Hg of soil, were conducted. It is concluded in this paper that free hydrocarbons are obviously better than other geochemical parameters and could be used for evaluation of oil and gas potential of TD-2 structure in the desert area. Shapes of near-surface geochemical anomalies and geochemical characteristic parameters suggested that TD-2 structure was a dry gas-bearing structure at the early-middle dissipation stage. So TD-2 structure should have some promising potential for oil-gas. Multi-parametric geochemical survey provided important information for further drilling exploration.

关键词：地球化学调查耗散结构塔里木盆地潜力评价沙漠地区 TD 油气圈闭中国

HYDROELASTIC FATIGUE ANALYSIS AND LONG-TERM STRESS PREDICTION OF SALS RISER

在线全文

学校读者我要写书评

暂无评论

China Ocean Engineering 1990年第4期5卷 385-395页

作者： Gan, xilin Zhu, Shengchang Zhang, Jinlun China Ship Scientific Research Cent Wuxi China

In this paper the stress transfer function of a riser is obtained by using the theory of hydroelasticity. The two-parameter wave spectrum group is formed through the joint distribution of wave height and period. The wave spectrum group is transformed into the stress spectrum group by virtue of the stress tranfer function. The fatigue life and extreme stress are predicted by applying the random fatigue analysis technique and long-term prediction theory. The design scheme of a SALS riser in the South China Sea is analysed.

关键词： Elasticity Stresses Prediction

Learning efficient text-to-image synthesis via interstage cross-sample similarity distillation

在线全文

学校读者我要写书评

暂无评论

Science China(Information Sciences) 2021年第2期64卷 19-30页

作者： Fengling MAO Bingpeng MA Hong CHANG Shiguang SHAN xilin CHEN School of Information Science and Technology ShanghaiTech University Key Laboratory of Intelligent Information Processing of Chinese Academy of Sciences (CAS) Institute of Computing TechnologyChinese Academy of Sciences University of Chinese Academy of Sciences CAS Center for Excellence in Brain Science and Intelligence Technology

For a given text, previous text-to-image synthesis methods commonly utilize a multistage generation model to produce images with high resolution in a coarse-to-fine manner. However, these methods ignore the interaction among stages, and they do not constrain the consistent cross-sample relations of images generated in different stages. These deficiencies result in inefficient generation and discrimination. In this study, we propose an interstage cross-sample similarity distillation model based on a generative adversarial network(GAN) for learning efficient text-to-image synthesis. To strengthen the interaction among stages,we achieve interstage knowledge distillation from the refined stage to the coarse stages with novel interstage cross-sample similarity distillation blocks. To enhance the constraint on the cross-sample relations of the images generated at different stages, we conduct cross-sample similarity distillation among the stages. Extensive experiments on the Oxford-102 and Caltech-UCSD Birds-200-2011(CUB) datasets show that our model generates visually pleasing images and achieves quantitatively comparable performance with state-of-the-art methods.

关键词： generative adversarialnetwork (GAN) text-to-image synthesis knowledge distillation

Large Eddy Simulation of a dilute particleladen turbulent flow over a backwardfacing step

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Science China(Technological Sciences) 2008年第11期51卷 1957-1970页

作者： ZHANG HuiQiang WANG Bing CHAN CheongKi WANG xilin Department of Engineering Mechanics Tsinghua UniversityBeijing 100084China Department of Applied Mathematics Hong Kong Polytechnic UniversityHong KongChina

Dilute gas-particle turbulent flows over a backward-facing step are numerically simulated by Large Eddy Simulation (LES) for the continuous phase and Lagran- gian particle trajectory method for the particle phase. Predicted results of mean velocities and fluctuating velocities of both phases agree well with the experimental data, and demonstrate that the main characteristics of the flow are accurately captured by the simulations. Characteristics of separation and reattachments as well as essential features of the coherent structure are obtained, in which the processes of vortex roll up, growth, pairing and breaking up are shown in details. Particle dispersions are then investigated through particles’ instantaneous distri- butions in coherent structure as well as the mean and fluctuating properties of particle number density (PND). The predicted mean PND agree well with experiment results. For small particles, the instantaneous distributions show much preferential concentration, while their mean PND shows more uniform distribution in down- stream region. On the contrary, for large particles, their instantaneous distributions are much uniform (without clear preferential concentration) due to less effect of large eddy coherent, while their mean PND across the section is not uniform for more particles are distributed in the main flow region. The preferential concentra- tion of particles by the large-scale eddies can lead to a high fluctuating PND.

关键词： two-phase flow particle dispersion Large Eddy Simulation backward-facing step flow spatially developing flow particle number density