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High Voltage 2024年第1期9卷 81-93页

作者： Jun xie Zhe Zhou Ziqian Liu Haonan Tian Sigang Zhang qing xie Hebei Provincial Key Laboratory of Power Transmission Equipment Security Defense North China Electric Power UniversityBaodingChina State Grid Gansu Electric Power Company LanzhouChina

Fibre-reinforced polymer(FRP)/rigid polyurethane foam(RPUF)interface is susceptible to moisture intrusion in addition to natural ageing during operation.This study investigated the influence of moisture intrusion on the FRP/RPUF interface under natural ageing using experiments and molecular dynamics(MD)simulations.Water absorption,shear strength,and leakage current tests were used to clarify the changes in the interface performance.The degradation mechanism of moisture intrusion at the interface under natural ageing was revealed by MD simulation and micro-characterisation.The results show that the natural ageing of interfacial materials will slightly reduce the quality of the interface but will reduce the water resistance of the material and promote the process of water intrusion into the interface.In addition,water mainly invades the interface through RPUF.After water penetration,the interfacial bonding strength and insulation performance significantly decreased.Plasticisation and hydrolysis of interfacial materials are the main reasons for decreased interfacial adhesion.Hydrolysis can cause irreversible damage to the interface,increasing interface defects and water absorption.The vicious cycle of material hydrolysis is the ultimate cause of interfacial debonding.The polar molecules produced by this process and the water absorbed by the interface caused the degradation of the interface insulation performance.

关键词： interface polyurethane interfacial

Necroptosis contributes to non-alcoholic fatty liver disease pathoetiology with promising diagnostic and therapeutic functions

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World Journal of Gastroenterology 2024年第14期30卷 1968-1981页

作者： Hong-Ju Sun Bo Jiao Yan Wang Yue-Hua Zhang Ge Chen Zi-Xuan Wang Hong Zhao qing xie Xiao-Hua Song Department of General Medicine Qingdao Central HospitalUniversity of Health and Rehabilitation Sciences(Qingdao Central Medical Group)Qingdao 266042Shandong ProvinceChina Department of Gastroenterology Qingdao Central HospitalUniversity of Health and Rehabilitation Sciences(Qingdao Central Medical Group)Qingdao 266042Shandong ProvinceChina Department of Medical Administration Qingdao Central HospitalUniversity of Health and Rehabilitation Sciences(Qingdao Central Medical Group)Qingdao 266042Shandong ProvinceChina qingdao Medical College Qingdao UniversityQingdao 266042Shandong ProvinceChina Department of Infectious Diseases Ruijin HospitalShanghai Jiao Tong University School of MedicineShanghai 200025China

Nonalcoholic fatty liver disease(NAFLD)is the most prevalent type of chronic liver disease.However,the disease is underappreciated as a remarkable chronic disorder as there are rare managing strategies.Several studies have focused on determining NAFLD-caused hepatocyte death to elucidate the disease pathoe-tiology and suggest functional therapeutic and diagnostic options.Pyroptosis,ferroptosis,and necroptosis are the main subtypes of non-apoptotic regulated cell deaths(RCDs),each of which represents particular characteristics.Considering the complexity of the findings,the present study aimed to review these types of RCDs and their contribution to NAFLD progression,and subsequently discuss in detail the role of necroptosis in the pathoetiology,diagnosis,and treatment of the disease.The study revealed that necroptosis is involved in the occurrence of NAFLD and its progression towards steatohepatitis and cancer,hence it has potential in diagnostic and therapeutic approaches.Nevertheless,further studies are necessary.

关键词： Nonalcoholic fatty liver disease Apoptosis Necroptosis Cell death Diagnosis Treatment

基于DPSR模型的城市水安全评价与保障能力提升

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长江科学院院报 2024年第7期41卷 41-47,56页

作者：谢庆长沙理工大学水利与环境工程学院长沙410114 中共湖南省委党校湖南经济社会发展研究中心长沙410006

水安全评价是水资源开发利用与保护的基础,提升城市水安全有利于促进生态环境保护,支撑经济社会高质量发展。基于驱动-压力-状态-响应(DPSR)模型构建以资源安全、社会安全和经济安全为核心的水安全评价指标体系,运用熵权法确定指标权重... 详细信息

水安全评价是水资源开发利用与保护的基础,提升城市水安全有利于促进生态环境保护,支撑经济社会高质量发展。基于驱动-压力-状态-响应(DPSR)模型构建以资源安全、社会安全和经济安全为核心的水安全评价指标体系,运用熵权法确定指标权重,以长沙市为实例,对“十三五”期间城市水安全状况进行评估与分析。结果表明:长沙市水安全状况尽管从2018年“不安全”等级提升至2020年“安全”等级,但状态不稳定,进而制定了加强保水工程建设、提升水环境质量、加强水灾害防治能力3个方案,综合考虑方案投入成本并对比水安全提升效果,给出了先后实施方案2—方案1—方案3的长沙市水安全提升优化路径。

关键词：城市水安全 DPSR模型熵权法长沙市提升路径

基于非靶向代谢组学的沙枣花、叶片和幼枝的挥发性成分分析

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植物生理学报 2024年第2期60卷 363-376页

作者：解庆刘志红山西农业大学林学院山西晋中030801

本文运用顶空固相微萃取-气相色谱-质谱联用技术(HS-SPME-GC-MS)研究了不同发育阶段沙枣花(花蕾、全开和凋谢)、叶片和幼枝的挥发性成分,并采用主成分分析(PCA)、正交偏最小二乘法判别分析(OPLS-DA)等方法筛选出差异代谢物。结果表明,... 详细信息

本文运用顶空固相微萃取-气相色谱-质谱联用技术(HS-SPME-GC-MS)研究了不同发育阶段沙枣花(花蕾、全开和凋谢)、叶片和幼枝的挥发性成分,并采用主成分分析(PCA)、正交偏最小二乘法判别分析(OPLS-DA)等方法筛选出差异代谢物。结果表明,沙枣挥发油以酯类、烃类、醇类和醛类物质为主,主要成分为肉桂酸乙酯、β-罗勒烯和4-己烯-1-醇乙酸酯等。代谢组学分析共筛选出17种差异代谢物。其中沙枣花蕾中的特征成分为α-橙花叔醇、反式-2-己烯醇、十一醛和β-罗勒烯;沙枣花全开时的特征成分为肉桂酸乙酯和安息香酸乙酯;凋谢后沙枣花的特征成分为癸醛、庚醛、植酮和2-甲基丁酸乙酯;沙枣叶片的特征成分为4-己烯-1-醇乙酸酯和叶醇而沙枣幼枝的特征成分为壬醛、顺式-3-己烯基异戊酸酯、苯乙醇和3-己烯-1-醇。沙枣花、叶片和幼枝挥发性成分的代谢组学分析,可为沙枣精油的综合开发利用提供一定理论依据。

关键词：沙枣挥发性成分顶空固相微萃取气相色谱-质谱联用非靶向代谢组学

Effecacy of Biejia(Carapax Trionycis) and Ezhu(Rhizoma Curcumae Phaeocaulis) couplet medicine on epithelial-mesenchymal transition, invasion and migration of MDA-MB-231 triple negative breast cancer cells via PI3K/Akt/mTOR signaling pathway

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Journal of Traditional Chinese Medicine 2021年第6期41卷 853-861页

作者： ZHU Manjing xie Su xie qing ZHU Jiulong HUANG Yazhen Guizhou Medical University Guiyang 550004China the Affiliated Hospital of Guizhou Medical University Guiyang 550004China

OBJECTIVE:To investigate the efficacy of Biejia(Carapax Trionycis)and Ezhu(Rhizoma Curcumae Phaeocaulis)couplet medicine on epithelial-mesenchymal transition(EMT),invasion and migration of MDA-MB-231 triple negative breast cancer(TNBC)cells based on PI3K/Akt/mTOR signaling pathway.METHODS:MDA-MB-231 cells were treated with different medicated serum as Biejia-,Ezhu-,Biejia-Ezhu(BJ-,EZ-,BJ-EZ-)groups,intervened with no drug rat serum and paclitaxel with final concentration of 33 nM(IC50)as negative and positive control(NC and PC)groups.CCK-8 assay,scratch test,and Transwell assay were used to examine cell proliferation,invasion,and migration.The expression of E-cadherin,N-cadherin,Vimentin,MMP-2,MMP-9,PI3K,Akt,p-Akt,mTOR,and p-mTOR was determined by Western blot,and the m RNA expression of PI3K,Akt and mTOR was determined by real-time polymerase chain reaction.RESULTS:BJ-EZ group inhibited proliferation after 24,48,and 72 h compared with the NC group(P<0.05,<0.01 or<0.001)and reduced the invasion and migration of MDA-MB-231 cells(P<0.01 or<0.001).In addition,BJ-EZ group upregulated the expression of E-cadherin,downregulated the expression of N-cadherin,Vimentin,MMP-2,and MMP-9(P<0.05,P<0.01 or P<0.001),and inhibited the m RNA and protein expression of PI3K,Akt(p-Akt),mTOR(p-mTOR)(P<0.05,<0.01 or<0.001).CONCLUSION:Biejia(Carapax Trionycis)and Ezhu(Rhizoma Curcumae Phaeocaulis)couplet medicine can inhibit the proliferation,invasion,migration and EMT of MDA-MB-231 cells through PI3K/Akt/mTOR signaling pathway,and the effect is better than that of Biejia(Carapax Trionycis)or Ezhu(Rhizoma Curcumae Phaeocaulis)alone.

关键词： triple negative breast neoplasms epithelial-mesenchymal transition PI3K/Akt/mTOR signal transduction Biejia(Carapax Trionycis) Ezhu(Rhizoma Curcumae Phaeocaulis)

Design and prototyping of the readout electronics for the transition radiation detector in the high energy cosmic radiation detection facility

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Nuclear Science and Techniques 2024年第4期35卷 189-199页

作者： Jie-Yu Zhu Yang-Zhou Su Hai-Bo Yang Fen-Hua Lu Yan Yang Xi-Wen Liu Ping Wei Shu-Cai Wan Hao-qing xie Xian-Qin Li Cong Dai Hui-Jun Hu Hong-Bang Liu Shu-Wen Tang Cheng-Xin Zhao Institute of Modern Physics Chinese Academy of SciencesLanzhou 730000China School of Nuclear Science and Technology University of Chinese Academy of SciencesBeijing 100049China Guangxi Key Laboratory for Relativistic Astrophysics School of Physical Science and TechnologyGuangxi UniversityNanning 530004China

The high energy cosmic-radiation detection(HERD)facility is planned to launch in 2027 and scheduled to be installed on the China Space Station.It serves as a dark matter particle detector,a cosmic ray instrument,and an observatory for high-energy gamma rays.A transition radiation detector placed on one of its lateral sides serves dual purpose,(ⅰ)calibrating HERD's electromagnetic calorimeter in the TeV energy range,and(ⅱ)serving as an independent detector for high-energy gamma rays.In this paper,the prototype readout electronics design of the transition radiation detector is demonstrated,which aims to accurately measure the charge of the anodes using the SAMPA application specific integrated circuit chip.The electronic performance of the prototype system is evaluated in terms of noise,linearity,and resolution.Through the presented design,each electronic channel can achieve a dynamic range of 0–100 fC,the RMS noise level not exceeding 0.15 fC,and the integral nonlinearity was<0.2%.To further verify the readout electronic performance,a joint test with the detector was carried out,and the results show that the prototype system can satisfy the requirements of the detector's scientific goals.

关键词： HERD Dark matter particle detection TRD Readout electronics SAMPA Data acquisition Performance test

资源配置视角下绿色金融对绿色技术创新的影响研究

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经济问题 2024年第4期 52-59页

作者：潘明清谢清华崔冉宿迁学院经济与管理学院江苏宿迁223800 湛江科技学院粤西数智会计发展研究中心广东湛江524086 广西财经学院金融与保险学院广西南宁530003

基于资源配置视角,探究绿色金融与绿色技术创新的影响效应和内在机制。研究发现:绿色金融有助于增强绿色技术创新能力,且该促进效应具有显著的区域异质性;从作用渠道看,绿色金融可以通过研发资本和研发人才两条传导机制增强绿色技术创... 详细信息

基于资源配置视角,探究绿色金融与绿色技术创新的影响效应和内在机制。研究发现:绿色金融有助于增强绿色技术创新能力,且该促进效应具有显著的区域异质性;从作用渠道看,绿色金融可以通过研发资本和研发人才两条传导机制增强绿色技术创新能力;从异质性效应看,劳动力与资本资源错配严重制约了绿色金融对绿色技术创新能力的促进作用,尤其是东部地区的抑制效应更强。进一步讨论发现,绿色金融、资源配置对绿色技术创新具有显著正向空间效应。研究结论丰富了绿色金融理论体系,为我国大力发展绿色金融,促进绿色技术创新提供理论和经验依据。

关键词：绿色金融资源错配绿色技术创新研发资本研发人才

重金属污染与生态风险评价——基于自组织地图和正矩阵分解的临澧县土壤研究

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Journal of Central South University 2024年第4期31卷 1371-1382页

作者：邹昊李武清任伯帜谢青蔡昭奇陈禄源王瑾 School of Civil Engineering Hunan University of Science and TechnologyXiangtan 411201China Institute of Geological Survey of Hunan Province Changsha 410083China School of Resource Security Hunan University of Science and TechnologyXiangtan 411201China School of Earth Science and Spatial Information Hunan University of Science and TechnologyXiangtan 411201China College of Foreign Languages Hunan UniversityChangsha 410082China

土壤重金属污染一直是环境科学中备受关注的问题。本文对中国临澧县土壤中六种重金属(As、Cd、Cr、Cu、Zn和Pb)的污染水平、分布、来源及其对生态环境的影响进行了分析。样本浓度分析结果显示Cd的浓度均超过背景值,超标率达到100%,其余... 详细信息

土壤重金属污染一直是环境科学中备受关注的问题。本文对中国临澧县土壤中六种重金属(As、Cd、Cr、Cu、Zn和Pb)的污染水平、分布、来源及其对生态环境的影响进行了分析。样本浓度分析结果显示Cd的浓度均超过背景值,超标率达到100%,其余元素的平均浓度与背景值相近,超标率均在13.5%以下。地累计指数和富集因子指数均显示Cd是污染最严重的元素,其他元素则处于轻度污染级别以下。自组织地图(SOM)和正矩阵分解(PMF)的分析结果显示农业活动是土壤中重金属元素主要来源之一,而自然风化和工业污染也会导致土壤污染。Cd是临澧县土壤中污染最显著的元素,对生态环境造成的影响最大,达到较高风险等级。本研究为降低土壤重金属污染和生态环境风险提供了重要参考,同时也为相关部门制定有效的污染防治、生态环境保护政策提供了理论指导。

关键词：生态风险正矩阵分解重金属污染土壤自组织地图

中国式学习型大国建设:内涵、特征与推进方略

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成人教育 2024年第2期44卷 1-6页

作者：张彧谢清理驻马店幼儿师范高等专科学校河南驻马店463000 玉林师范学院广西玉林537000

中国式学习型大国是中国式现代化的重要组成部分和显著体现,推进中国式学习型大国建设应理解和把握其意义、内涵、特征与方略。文章从中国发展、发展中国家改革和人类发展等视角澄清了中国式学习型大国建设的世界历史意义,从根本保障、... 详细信息

中国式学习型大国是中国式现代化的重要组成部分和显著体现,推进中国式学习型大国建设应理解和把握其意义、内涵、特征与方略。文章从中国发展、发展中国家改革和人类发展等视角澄清了中国式学习型大国建设的世界历史意义,从根本保障、根本目的、核心主题、根本依靠和根本动力等角度阐明了中国式学习型大国建设的科学内涵,从规模化、普惠性、优质化、可持续性、包容性等方面分析了中国式学习型大国建设的基本特征,从学校继续教育、社会继续教育、终身学习文化、终身学习治理和国际话语权等维度建构了中国式学习型大国建设的推进方略。

关键词：中国式现代化学习型大国终身学习继续教育国际话语权

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文以情传:文化类综艺节目的共情传播机制

现代传播（中国传媒大学学报） 2024年第2期46卷 86-92,100页

作者：谢清果韦俊全厦门大学新闻传播学院

中国文化类综艺节目在文化主体性觉醒与影视新技术赋能的双重加持下,不断实现着自身审美之塑新与言说之飞跃。文化类综艺节目“大爆”与“出圈”,不仅得益于视听方式、文化内容的创新,更在于其通过表层视听展演触达到受众深层情感与心理... 详细信息

中国文化类综艺节目在文化主体性觉醒与影视新技术赋能的双重加持下,不断实现着自身审美之塑新与言说之飞跃。文化类综艺节目“大爆”与“出圈”,不仅得益于视听方式、文化内容的创新,更在于其通过表层视听展演触达到受众深层情感与心理,实现社会的情感同频共振。同时,共情传播标示着人类传播学从以往聚焦客观理性逐渐关注到人的情感本位。鉴于此,亟待从共情传播的视角,透过对文化类综艺节目共情传播现象及其内在机制的探析,深入去探讨文化类综艺何以披文入情、以情动人,以期思索文化类综艺节目的创作与传播。

关键词：共情机制情感传播共情传播文化类综艺节目中华文化传播