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Application Research of PETD Combined with MRI Nerve Root Water Imaging in the Minimally Invasive Treatment of LDH

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International Journal of Clinical Medicine 2024年第4期15卷 167-176页

作者： Guanhua Wang Zhe Shen Jinben Yu Shengjie Xu Weinan Xu Bing Xu xiaoyu ye Wenzhou Combined Traditional Chinese and Western Medicine Hospital of Zhejiang Chinese Medicine University Wenzhou China The Third Clinical Medical College Zhejiang Chinese Medical University Hangzhou China

Objective: This study aims to evaluate the safety and efficacy of PETD combined with nerve root water imaging of MRI for the treatment of lumbar disc herniation. Methods: A retrospective review was performed on 62 patients with lumbar disc herniation from March 2019 to March 2021. The study included an experimental group of 30 patients and a control group of 32 patients. The experimental group underwent PETD combined with nerve root water imaging of MRI, while the control group received traditional PETD treatment. The visual analogue scoring method (VAS score), and JOA lumbar spine function score before and after surgery were compared between the two groups, and efficacy was assessed and compared using the MacNab score. Results: The mean operation time was significantly reduced in the experimental group (56.43 ±10.40 minutes) compared to the control group (65.69 ±14.12 minutes). The VAS score was compared between the two groups with preoperative (p = 0.624), one month after surgery (p = 0.325), three months after surgery (p = 0.676), one year after surgery (p = 0.341);The JOA score was compared between the two groups with preoperative (p = 0.961), one month after the surgery (p = 0.266), three months after surgery (p = 0.185), one year after surgery (p = 0.870), they were no significant statistical difference;The efficacy evaluation of the last follow-up Macnab showed that all the 30 patients in the experimental group were excellent, 31 of 32 patients in the control group were excellent, 1 case was good;There was no statistical difference in the comparison between the two groups (p > 0.05). Conclusion: The study concludes that the combined approach of PETD with nerve root water imaging of MRI is a safe, effective, and more efficient alternative to conventional PETD for treating lumbar disc herniation.

关键词： Lumbar Disc Herniation Nerve Root Water Imaging Percutaneous Interforaminal Endoscopy Minimally Invasive Spine Surgery Discectomy

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空位浓度对γ-TiAl涂层阻尼性能的影响

稀有金属材料与工程 2024年第6期53卷 1761-1769页

作者：王宁杨帆叶枭宇邵长铖杜广煜姜文全辽宁石油化工大学机械工程学院辽宁抚顺113005 辽宁石油化工大学石油天然气工程学院辽宁抚顺113005 东北大学机械工程及自动化学院辽宁沈阳110819

为了研究空位缺陷对γ-TiAl涂层阻尼性能的影响,采用分子动力学方法(MD)对不同空位浓度的γ-TiAl涂层模型进行往复振动模拟计算。比较分析了应力-应变、储存势能、位错线密度、缺陷面积的变化及微观结构的变化机制。结果表明:随着空位... 详细信息

为了研究空位缺陷对γ-TiAl涂层阻尼性能的影响,采用分子动力学方法(MD)对不同空位浓度的γ-TiAl涂层模型进行往复振动模拟计算。比较分析了应力-应变、储存势能、位错线密度、缺陷面积的变化及微观结构的变化机制。结果表明:随着空位浓度的升高,γ-TiAl涂层能耗逐渐增加,弹性模量逐渐减小,涂层提前发生疲劳破坏;不同空位浓度γ-TiAl涂层的储存势能均呈周期性变化,变化幅度随空位浓度的升高而逐渐减小;在振动模拟过程中,空位缺陷会演化为位错线及其它缺陷,导致位错密度和缺陷面积升高,不同缺陷的运动、演化及湮灭是γ-TiAl涂层产生能耗的主要来源;另外,高空位浓度的γ-TiAl涂层内部产生较多的塑性变形,出现颈缩和孔洞等缺陷,使阻尼发生失效。

关键词：阻尼性能分子动力学 γ-TiAl涂层位错密度能量耗散

基于线性化模型组的无人直升机半物理实时仿真技术研究

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机械与电子 2024年第5期42卷 50-56页

作者：姚志豪祖家奎李晨毓叶晓宇南京航空航天大学自动化学院江苏南京211106

针对无人直升机非线性动力学模型的建模难度大、置信度低及不利于进行系统仿真验证问题展开研究。首先介绍了无人直升机的线性化模型组并围绕其开展非线性模型线性化处理研究;接着阐述基于线性化模型组的实时仿真算法及计算流程;最后设... 详细信息

针对无人直升机非线性动力学模型的建模难度大、置信度低及不利于进行系统仿真验证问题展开研究。首先介绍了无人直升机的线性化模型组并围绕其开展非线性模型线性化处理研究;接着阐述基于线性化模型组的实时仿真算法及计算流程;最后设计了基于线性化模型组的半物理仿真环境,完成实时仿真软件、仿真监控软件及FlightGear通信设计并通过仿真验证。结果表明,基于线性化模型组半物理实时仿真系统能够很好地满足工程需求,达到了预期的研究目标。

关键词：无人直升机非线性动力学模型线性化模型组半物理仿真

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无人机多源冗余传感器容错估计算法研究

机械与电子 2024年第1期42卷 47-52页

作者：桑可可祖家奎叶晓宇刘世龙南京航空航天大学自动化学院江苏南京211106

在无人机应用中,单余度传感器系统在定位导航精度、多任务处理与决策能力以及系统的鲁棒性和可靠性等方面有待进一步提升和改善。鉴于此,设计三余度传感器的冗余配置,对相应的余度系统采用非相似的滤波算法,提出一种多源冗余传感器容错... 详细信息

在无人机应用中,单余度传感器系统在定位导航精度、多任务处理与决策能力以及系统的鲁棒性和可靠性等方面有待进一步提升和改善。鉴于此,设计三余度传感器的冗余配置,对相应的余度系统采用非相似的滤波算法,提出一种多源冗余传感器容错估计算法对系统软/硬故障进行检测与隔离,通过加权平均投票计算出余度系统的权重因子进而有效地隔离故障系统,保证系统姿态信息的精度和可靠性。试验结果表明,该方法能够实现余度系统的软/硬故障的检测、识别与隔离,具有较好的实时性。

关键词：传感器可靠性多源冗余姿态信息实时性

Advancing cell-based therapy in sepsis:An anesthesia outlook

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Chinese Medical Journal 2024年第13期137卷 1522-1534页

作者： Hui ye xiaoyu Zou Xiangming Fang Department of Anesthesiology and Intensive Care The First Affiliated HospitalSchool of MedicineZhejiang UniversityHangzhouZhejiang 310003China The Children’s Hospital National Clinical Research Center for Child HealthSchool of MedicineZhejiang UniversityHangzhouZhejiang 312000China

Sepsis poses a health challenge globally owing to markedly high rates of morbidity and *** employing bundle therapy over two decades,approaches including transient organ supportive therapy and clinical trials focusing on signaling pathways have failed in effectively reversing multiple organ failure in patients with *** and appropriate perioperative management for surgical patients with concurrent sepsis is ***,innovative therapies focusing on remedying organ injuries are *** therapy has emerged as a promising therapeutic avenue for repairing local damage to vital organs and restoring homeostasis during perioperative treatment for *** the pivotal role of immune cell responses in the pathogenesis of sepsis,stem cell-based interventions that primarily modulate immune responses by interacting with multiple immune cells have progressed into clinical *** strides made in single-cell sequencing and gene-editing technologies have advanced the understanding of disease-specific immune responses in *** antigen receptor(CAR)-immune cell therapy offers an intriguing option for the treatment of *** review provides a concise overview of immune cell therapy,its current status,and the strides made in the context of sepsis research,discussing potential strategies for the management of patients with sepsis during perioperative stages.

关键词： Sepsis Perioperative Receptors,chimeric antigen Immunotherapy,adoptive Perfusion Tissue repair Multiple organ failure Shock,septic

High temperature treatment induced production of unreduced 2n pollen in Camellia oleifera

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Horticultural Plant Journal 2024年第3期10卷 879-896页

作者： Hongda Deng xiaoyu Zhang Song Sheng Yuxun Huang Ziqi ye Tongyue Zhang Xing Liu Zhiqiang Han The Laboratory of Forestry Genetics Central South University of Forestry and TechnologyChangshaHunan 410004China Yuelushan Laboratory ChangshaHunan 410128China Key Laboratory of Cultivation and Protection for Non-Wood Forest Trees of Ministry of Education Central South University of Forestry and TechnologyChangshaHunan 410004China National Forest and Seedling Workstation of Hunan Province The Forestry Department of Hunan ProvinceChangshaHunan 410004China

Unreduced gametes through chromosome doubling play a major role in the process of plant *** previous work confirmed that Camellia oleifera can produce natural 2n pollen,and it is possible to induce the 2n pollen formation by high temperature *** study focused on the optimization of the 2n pollen induction technique and the mechanisms of high temperature-induced2n pollen formation in *** found that the optimal protocol for inducing 2n pollen via high temperature was to perform 45℃with4 h at the prophaseⅠstage of the pollen mother cells(PMCs).Meanwhile,high temperature significantly decreased the yield and fertility of2n *** the observation of meiosis,abnormal chromosome and cytological behaviour was discovered under high-temperature treatment,and we confirmed that the formation of 2n pollen is caused by abnormal cell *** on weighted gene co-expression network analysis,fifteen hub genes related to cell cycle control were *** male flower buds were exposed to heat shock,polygalacturonase gene(CoPGX3)was significantly *** inferred that high temperature causes the CoPGX3 gene to be overexpressed and that CoPGX3 is redistributed into the cytosol where it degrades cytoplasmic pectin,which leads to an abnormal cell ***,abnormal cytokinesis resulted in the formation of dyads and triads,and PMCs divided to produce 2n *** findings provide new insights into the mechanism of 2n pollen induced by high temperature in a woody plant and lay a foundation for further ploidy breeding of ***.

关键词： Camellia oleifera Pollen mother cells(PMCs) High temperature Meiosis 2n pollen CoPGX3

Bioinspired Multifunctional Self-Sensing Actuated Gradient Hydrogel for Soft-Hard Robot Remote Interaction

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Nano-Micro Letters 2024年第4期16卷 139-152页

作者： He Liu Haoxiang Chu Hailiang Yuan Deliang Li Weisi Deng Zhiwei Fu Ruonan Liu Yiying Liu Yixuan Han Yanpeng Wang Yue Zhao xiaoyu Cui ye Tian College of Medicine and Biological Information Engineering Northeastern UniversityShenyang 110169People’s Republic of China Foshan Graduate School of Innovation Northeastern UniversityFoshan 528300People’s Republic of China

The development of bioinspired gradient hydrogels with self-sensing actuated capabilities for remote interaction with soft-hard robots remains a challenging endeavor. Here, we propose a novel multifunctional self-sensing actuated gradient hydrogel that combines ultrafast actuation and high sensitivity for remote interaction with robotic hand. The gradient network structure, achieved through a wettability difference method involving the rapid precipitation of MoO_(2) nanosheets, introduces hydrophilic disparities between two sides within hydrogel. This distinctive approach bestows the hydrogel with ultrafast thermo-responsive actuation(21° s^(-1)) and enhanced photothermal efficiency(increase by 3.7 ℃ s^(-1) under 808 nm near-infrared). Moreover, the local cross-linking of sodium alginate with Ca^(2+) endows the hydrogel with programmable deformability and information display capabilities. Additionally, the hydrogel exhibits high sensitivity(gauge factor 3.94 within a wide strain range of 600%), fast response times(140 ms) and good cycling stability. Leveraging these exceptional properties, we incorporate the hydrogel into various soft actuators, including soft gripper, artificial iris, and bioinspired jellyfish, as well as wearable electronics capable of precise human motion and physiological signal detection. Furthermore, through the synergistic combination of remarkable actuation and sensitivity, we realize a self-sensing touch bioinspired tongue. Notably, by employing quantitative analysis of actuation-sensing, we realize remote interaction between soft-hard robot via the Internet of Things. The multifunctional self-sensing actuated gradient hydrogel presented in this study provides a new insight for advanced somatosensory materials, self-feedback intelligent soft robots and human–machine interactions.

关键词： Self-sensing Gradient structure Bioinspired actuator Hydrogel sensor Remote interaction

多学科协作营养护理对乳腺癌术后化疗患者营养状况及免疫功能的影响

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中国医药科学 2024年第6期14卷 101-104,142页

作者：何美娟叶晓羽林丽清福建中医药大学附属第三人民医院肿瘤科福建福州350108

目的探析多学科协作营养护理对乳腺癌术后化疗患者营养状况的影响。方法选取2020年1月至2022年12月福建中医药大学附属第三人民医院收治的乳腺癌术后化疗患者80例,依据随机数表法分为两组,每组各40例。对照组采用传统护理干预,观察组采... 详细信息

目的探析多学科协作营养护理对乳腺癌术后化疗患者营养状况的影响。方法选取2020年1月至2022年12月福建中医药大学附属第三人民医院收治的乳腺癌术后化疗患者80例,依据随机数表法分为两组,每组各40例。对照组采用传统护理干预,观察组采用多学科协作营养护理干预。比较两组营养状况、遵医行为及免疫功能。结果两组干预前营养状况水平比较,差异无统计学意义(P>0.05),观察组干预后白蛋白(ALB)、血红蛋白(Hb)水平高于对照组,差异有统计学意义(P0.05),观察组干预后分化簇3^(+)(CD3^(+))、分化簇4^(+)(CD4^(+))、CD4^(+)/分化簇8^(+)(CD8^(+))水平高于对照组,差异有统计学意义(P0.05),干预后与对照组比较,观察组评分更高(P<0.05)。结论乳腺癌术后化疗患者采用多学科协作营养护理效果明显,患者营养状况得到明显改善,患者遵医行为提升,同时其身体免疫功能显著提高,临床上可借鉴及推广。

关键词：乳腺癌术后化疗多学科协作营养护理营养状况

体育旅游专业人才培养研究:需求、问题与策略

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盐城工学院学报（社会科学版） 2022年第5期35卷 74-79页

作者：叶小瑜南京体育学院体育产业与休闲学院江苏南京210014

运用文献资料法和文本分析法对我国体育旅游专业人才需求与培养现状进行研究。研究认为:1,在国家政策助力,经济新增长点驱动,人民美好生活需求引领和冬奥旅游热潮带动下,我国就业市场呈现出对体育旅游专业人才的迫切需求。2,探究我国体... 详细信息

运用文献资料法和文本分析法对我国体育旅游专业人才需求与培养现状进行研究。研究认为:1,在国家政策助力,经济新增长点驱动,人民美好生活需求引领和冬奥旅游热潮带动下,我国就业市场呈现出对体育旅游专业人才的迫切需求。2,探究我国体育旅游专业人才培养中存在的人才培养体系不明晰,专业特色不够鲜明;课程体系全而不专,实践环节重视不够;教学方式创新不足,评价手段较为单一;实践平台有待搭建,就业渠道亟须拓展等问题。3,提出对接国家战略和地区需求明确专业定位,聚焦专业核心技能重构课程体系,创新人才培养理念和教学方式方法,产学研多元协同推进实践平台建设,“政企校联动”精准对接促就业等策略。

关键词：体育旅游市场需求人才培养京张文化旅游带冰雪运动北京冬奥会