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Frontiers of Earth Science 2018年第3期12卷 532-544页

作者： xiaoyin tang Shuchun YANG Shengbiao HU Geothermal and Environmental Research Laboratory Xi'an Jiaotong University Xi'an 710049 China CNOOC Research Institute Beijing 100027 China Institute of Geology and Geophysics Chinese Academy of Sciences Beijing 100029 China

The Baiyun Sag, located in the deep-water area of the northern South China Sea, is the largest and deepest subbasin in the Pearl River Mouth Basin and one of the most important hydrocarbon-accumulation depression areas in China. Thermal history is widely thought to be of great importance in oil and gas potential assessment of a basin as it controls the timing of hydrocarbon generation and expulsion from the source rock. In order to unravel the paleo-heat flow of the Baiyun Sag, we first analyzed tectonic subsidence of 55 pseudo-wells constructed based on newly interpreted seismic profiles, along with three drilled wells. We then carried out thermal modeling using the multi-stage finite stretching method and calibrated the results using collected present-day vitrinite reflectance data and temperature data. Results indicate that the first and second heating of the Baiyun Sag after 49 Ma ceased at 33.9 Ma and 23 Ma. Reconstructed average basal paleo- heat flow values at the end of the rifting periods are -57.7- 86.2 mW/m2 and -66.7-97.3 mW/m2, respectively. Following the last heating period at 23 Ma, the study area has undergone a persistent thermal attenuation phase, and basal heat flow has cooled down to ～64.0-79.2 mW/m2 at present.

关键词： thermal history tectonic subsidence Baiyun Sag deep-water area South China Sea

How mammalian piRNAs instruct de novo DNA methylation of transposons

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Signal Transduction and Targeted Therapy 2020年第1期5卷 884-885页

作者： Zhiqing Li xiaoyin tang En-Zhi Shen Key Laboratory of Growth Control and Translational Research of Zhejiang Province School of Life SciencesWestlake UniversityHangzhouZhejiangChina Institute of Biology Westlake Institute for Advanced StudyHangzhouZhejiangChina Fudan University ShanghaiChina College of Life Sciences Zhejiang UniversityHangzhouZhejiangChina

A recent study published in Nature by Zoch et *** a novel MIWI2-associated protein SPOCD1 and shows its requirement for piRNA-guided young transposable elements(TEs)methylation and silencing.1 This research provided t... 详细信息

关键词： al instru insight

Zircon U-Pb geochronology,Hf isotopes,and geochemistry constraints on the age and tectonic affinity of the basement granitoids from the Qiongdongnan Basin,northern South China Sea

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Acta Oceanologica Sinica 2023年第3期42卷 19-30页

作者： Lijun Mi xiaoyin tang Haizhang Yang Shuchun Yang Shuai Guo China National Offshore Oil Corporation(CNOOC)Research Center Beijing 100028China Institute of Geomechanics Chinese Academy of Geological SciencesBeijing 100081China Key Laboratory of Paleomagnetism and Tectonic Reconstruction Ministry of Natural ResourcesBeijing 100081China Key Laboratory of Petroleum Geomechanics China Geological SurveyBeijing 100081China

Studies in the northern South China Sea(SCS)basement remain important for understanding the evolution of the Southeast Asian continental *** to a thick cover of sediments and scarce borehole penetration,little is known about the age and tectonic affinity of this *** this study,an integrated study of zircon U-Pb geochronology,Hf isotopes,and whole-rock major and trace elements on seven basement granitoids from seven boreholes of Qiongdongnan Basin has been carried *** zircon U-Pb results for these granitoids present middle-late Permian((270.0±1.2)Ma;(253±3.4)Ma),middle to late Triassic((246.2±3.4)Ma;(239.3±0.96)Ma;(237.9±0.99)Ma;(228.9±1.0)Ma)and Late Cretaceous ages((120.6±0.6)Ma).New data from this study,in combination with the previous dataset,indicates that granitoid ages in northern SCS basement vary from 270 Ma to 70.5 Ma,with three age groups of 270–196 Ma,162–142 Ma,and 137–71 Ma,*** for the late Paleozoic-Mesozoic rocks in the basement of the northern SCS,a few old zircon grains with the age of(2708.1±17)Ma to(2166.6±19)Ma provide clues to the existence of the pre-Proterozoic *** geochemical signatures indicate that the middle Permian-early Cretaceous granitoids from the Qiongdongnan Basin are I-type granites formed in a volcanic arc environment,which were probably related to the subduction of the Paleo-Pacific Plate.

关键词： Qiongdongnan Basin basement granitoids geochemistry U-Pb and Hf isotopes Paleo-Pacific Plate subduction

Thermal and exhumation history of the Songnan Low Uplift,Qiongdongnan Basin:constraints from the apatite fission-track and zircon(U-Th)/He thermochronology

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Acta Oceanologica Sinica 2024年第4期43卷 40-49页

作者： xiaoyin tang Kaixun Zhang Shuchun Yang Shuai Guo Xinyan Zhao Zhizhao Bai Institute of Geomechanics Chinese Academy of Geological SciencesBeijing 100081China Key Laboratory of Paleomagnetism and Tectonic Reconstruction Ministry of Natural ResourcesBeijing 100081China Key Laboratory of Petroleum Geomechanics China Geological SurveyBeijing 100081China China National Offshore Oil Corporation(CNOOC)Research Center Beijing 100028China

Significant advancements have been made in the study of Mesozoic granite buried hills in the Songnan Low Uplift(SNLU)of the Qiongdongnan *** findings indicate that the bedrock buried hills in this basin hold great potential for *** samples taken from the granite buried hills in the SNLU were analyzed using apatite fission track(AFT)and zircon(U-Th)/He data to unravel the thermal history of the basement *** information is crucial for understanding the processes of exhumation and alteration that occurred after its *** modeling of a sample from the western bulge of the SNLU revealed a prolonged cooling event from the late Mesozoic to the Oligocene period(~80-23.8 Ma),followed by a heating stage from the Miocene epoch until the present(~23.8 Ma to present).In contrast,the sample from the eastern bulge experienced a more complex thermal *** underwent two cooling stages during the late Mesozoic to late Eocene period(~80-36.4 Ma)and the late Oligocene period(~30-23.8 Ma),interspersed with two heating phases during the late Eocene to early Oligocene period(~36.4-30 Ma)and the Miocene epoch to recent times(~23.8-0 Ma),*** differences in exhumation histories between the western and eastern bulges during the late Eocene to Oligocene period in the SNLU can likely be attributed to differences in fault *** typical passive continental margin basins,the SNLU has experienced accelerated subsidence after the rifting phase,which began around 5.2 Ma *** possible mechanism for this abnormal post-rifting subsidence may be the decay or movement of the deep thermal source and the rapid cooling of the ***-term and multi-episodic cooling and exhumation processes play a key role in the alteration of bedrock and contribute to the formation of *** the other hand,rapid post-rifting subsidence(sedimentation)promotes the formation of cap rocks.

关键词： granite buried hills (U-Th)/He dating fission-track dating exhumation Songnan Low Uplift

Tectono-thermal evolution of the Liwan Sag, deepwater area in the Zhujiang River Mouth Basin, northern South China Sea

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Acta Oceanologica Sinica 2018年第2期37卷 66-75页

作者： tang xiaoyin HUANG Shaopeng YANG Shuchun JIANG Guangzheng JI Mo HU Shengbiao Geothermal and Environmental Research Laboratory Xi'an Jiaotong University Xi'an 710049 China State Key Laboratory of Lithospheric Evolution Institute of Geology and Geophysics Chinese Academy of Sciences Beijing 100049 China CNOOC Research Institute Beijing 100027 China

The Liwan Sag, with an area of 4 000 km-2, is one of the deepwater sags in the Zhujiang River（Pearl River） Mouth Basin, northern South China Sea. Inspired by the exploration success in oil and gas resources in the deepwater sags worldwide, we conducted the thermal modeling to investigate the tectono-thermal history of the Liwan Sag,which has been widely thought to be important to understand tectonic activities as well as hydrocarbon potential of a basin. Using the multi-stage finite stretching model, the tectonic subsidence history and the thermal history have been obtained for 12 artificial wells, which were constructed on basis of one seismic profile newly acquired in the study area. Two stages of rifting during the time periods of 49–33.9 Ma and 33.9–23 Ma can be recognized from the tectonic subsidence pattern, and there are two phases of heating processes corresponding to the *** reconstructed average basal paleo-heat flow values at the end of the rifting events are -70.5 and -94.2 mW/m^2 respectively. Following the heating periods, the study area has undergone a persistent thermal attenuation phase since 23 Ma and the basal heat flow cooled down to -71.8–82.5 mW/m^2 at present.

关键词： tectono-thermal evolution thermal history heat flow deepwater area Liwan Sag

Tectonic subsidence of the Zhu I Sub-basin in the Pearl River Mouth Basin, northern South China Sea

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Frontiers of Structural and Civil Engineering 2017年第4期11卷 729-739页

作者： xiaoyin tang Shuchun YANG Junzhang ZHU Zulie LONG Guangzheng JIANG Shaopeng HUANG Shengbiao HU Geothermal and Environmental Research Laboratory Xi'an Jiaotong University Xi'an 710049 China State Key Laboratory of Lithospheric Evolution Institute of Geology and Geophysics Chinese Academy of Sciences Beijing 100029 China CNOOC Research Institute Beijing 100027 China Shenzhen Branch of China National Offshore Oil Corporation Ltd Guangzhou 510240 China Department of Earth and Environmental Sciences University of Michigan Ann Arbor MI 48109-1005 USA

The Pearl River Mouth Basin, which is situated on the northern margin of the South China Sea, has attracted great attention not only because of its tectonic setting but also because of its abundant hydrocarbon resources. We have analyzed the Cenozoic tectonic subsidence history of 4 drilled wells and 43 artificial wells from the Zhu 1 Sub-basin of the Pearl River Mouth Basin by back-stripping, using newly interpreted seismic profiles. We also calculated the average tectonic sub- sidence rates of the four sags in the Zhu 1 Sub-basin. The rifting and post-rifting stages are separated by abrupt changes in the tectonic subsidence curves and average subsidence rates. In the eastem sags of the Zhu 1 Sub- basin, tectonic subsidence started to slow at ca. 30 Ma, compared with ca. 23.8 Ma in the western sags. This probably corresponds to the timing of break-up and suggests that tiffing in the Pearl River Mouth Basin ended earlier in the eastern sags than in the western sags. Anomalously accelerated tectonic subsidence occurred at 17.5-16.4 Ma during the post-tiffing stage, with average subsidence rates as high as 301.9 m/Myr. This distin- guishes the Pearl River Mouth Basin from classical Atlantic passive continental marginal basins, which demonstrate exponentially decaying post-rift tectonic subsidence.

关键词： tectonic subsidence Zhu 1 Sub-basin back-stripping Pearl River Mouth Basin South China Sea

Combined local therapy and CAR-GPC3 T-cell therapy in advanced hepatocellular carcinoma:a proof-of-concept treatment strategy

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Cancer Communications 2023年第9期43卷 1064-1068页

作者： Yaoping Shi Donghua Shi Jiachang Chi Dan Cui xiaoyin tang Yan Lin Siying Wang Zonghai Li Haojie Jin Bo Zhai Department of Interventional Oncology State Key Laboratory of Systems Medicine for CancerRenji HospitalShanghai Jiao Tong University School of MedicineShanghaiP. R. China Shanghai Cancer Institute State Key Laboratory of Systems Medicine for CancerRenji HospitalShanghai Jiao Tong University School of MedicineShanghaiP. R. China CARsgen Therapeutics Ltd. ShanghaiP.R.China

Dear Editor,Available evidence regarding the most suitable treatment strategies for hepatocellular carcinoma(HCC)with inferior vena cava tumor thrombus(IVCTT)is extremely limited,and the median overall survival time for these patients after liver resection is only 17.76 months[1].Other local or systemic treatments for HCC with IVCTT result in a median overall survival time ranging from 5.88 to 15.36 months[1–3].Thus,new therapeutic strategies are urgently needed to improve the survival of HCC patients with *** antigen receptor(CAR)T-cell therapy has seen success in treating B-cell neoplasms with impressive outcomes[4].However,this therapy alone has shown limited efficacy on solid tumors,such as HCC[5].

关键词： neoplasms hepatocellular treatment

交通改善、市场需求与城市生产率——兼论城市规模的调节效应

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城市发展研究 2024年第11期31卷 39-46+72页

作者：汤小银安虎森东北师范大学地理科学学院南开大学21世纪马克思主义研究院

城市作为资源要素集聚的空间载体，其规模决定了资源要素的分配和利用方式，从而对城市生产率产生影响。交通基础设施改善、市场需求规模增加会加快要素自由流动，促进城市要素集聚，因而有必要进一步探讨交通基础设施、市场需求规模和... 详细信息

城市作为资源要素集聚的空间载体，其规模决定了资源要素的分配和利用方式，从而对城市生产率产生影响。交通基础设施改善、市场需求规模增加会加快要素自由流动，促进城市要素集聚，因而有必要进一步探讨交通基础设施、市场需求规模和城市规模对城市生产率的协同影响。为了试图回答上述问题，在Henderson理论模型的基础上，纳入新的参数进行了理论探讨，并结合中国101个不同规模等级城市2015-2021年的平衡面板数据进行了实证检验。结果显示：市场需求规模扩大和交通基础设施改善将显著促进城市生产率的提高，且城市规模在其中发挥了调节作用。异质性分析也表明，城市规模和城市区位也都发挥着重要影响。

关键词：交通基础设施市场需求规模城市规模城市生产率要素集聚资源配置

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大地电磁测深在火山区地热研究中的应用

岩石学报 2017年第1期33卷 279-290页

作者：张炯黄少鹏傅饶唐晓音西安交通大学全球环境变化研究院地热与环境研究实验室西安710049 美国密歇根大学地球与环境科学系安娜堡MI48109-1005

大地电磁测深(MT)由于勘探深度范围较大,且对温度、流体、岩浆房和岩性等与热储相关的地质条件的敏感度较高,因而成为火山区地热勘探和岩石圈结构研究中常用的一种地球物理勘探手段。地壳和上地幔的电性结构与热结构之间存在着密切的联... 详细信息

大地电磁测深(MT)由于勘探深度范围较大,且对温度、流体、岩浆房和岩性等与热储相关的地质条件的敏感度较高,因而成为火山区地热勘探和岩石圈结构研究中常用的一种地球物理勘探手段。地壳和上地幔的电性结构与热结构之间存在着密切的联系,通过解读二者的关系,可以刻画更为精细的岩石圈结构模型,进而掌握火山区的构造特征和热演化过程,了解其岩石圈地球动力学机制。本文着重介绍了MT方法的原理以及从野外数据采集到后期数据处理的过程,综述了MT法的应用特点以及电导率与温度之间的关系,通过实例分析,介绍了国际上这一方法在火山区地热勘探和岩石圈热结构研究中的应用进展,展示了MT法在新西兰Taupo火山区Ngatamariki高温地热田0~3km地热资源勘探中的应用;以埃塞俄比亚Afar省的Tendaho地热田和Badi火山为例,分别讨论了0~20km和0~50km不同深度的电性结构特征及其与温度存在的内在联系,探讨了形成火山的驱动机制;以日本九州岛的Shinmoe-dake火山为例,介绍了大地电磁测深和温度监测在火山监测方面的应用。最后简述了国内MT法在火山区的应用进展以及存在的问题,并利用上地幔电导率与温度的关系以及岩石圈内硅酸盐熔体不同含水量引起的电导率随温度的变化关系,初步估算了长白山天池和阿尔山火山区的莫霍面以下的温度以及长白山天池火山区的高温岩浆房温度。

关键词：地热研究火山大地电磁测深岩浆房

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新发展格局下实现区域协调发展的路径探析

南京社会科学 2021年第8期 29-37页

作者：安虎森汤小银东北师范大学地理科学学院长春130024

我国区域协调发展,是一条通过不断进行理论和实践探索而逐步完善的具有中国特色的多元渐进式区域发展道路。区内区际发展不平衡不充分仍是我国区域经济发展的矛盾的主要方面,是实现区域协调发展所需攻破的最主要的堡垒。本文深入分析了... 详细信息

我国区域协调发展,是一条通过不断进行理论和实践探索而逐步完善的具有中国特色的多元渐进式区域发展道路。区内区际发展不平衡不充分仍是我国区域经济发展的矛盾的主要方面,是实现区域协调发展所需攻破的最主要的堡垒。本文深入分析了我国区域协调发展实践中存在的问题,提出了立足区域多元层次结构,精准制定发展目标和战略;加强区域多元开放联动,优化国土空间布局;健全区域多元协调机制,切实增进民生福祉的实现区域协调发展的有效路径。

关键词：区域协调发展不平衡不充分发展新发展格局新发展理念