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Effect of Sea Spray on the Numerical Simulation of Super Typhoon ‘Ewiniar’

Journal of Ocean University of China 2008年第4期7卷 362-372页

作者： ZHENG Jing fei Jianfang DU Tao WANG Yuan CUI xiaoyan HUANG Xiaogang Qiming Institute of Meteorology PLA University of Science ＆ Technology Nanjing 211101 P. R. China College of Physical and Environmental Oceanography Ocean University of China Qingdao 266100 P R. China Department of Atmospheric Science Nanjing University Nanjing 210093 P R. China Institute of Aeronautical Meteorology Air Force Academy of Equipment Beijing 100085 P. R. China Meteorology Observation Navy ofNo.91774 Shanghai 200083 R R. China

To study the potential effect of sea spray on the evolution of typhoons,two kinds of sea spray flux parameterization schemes developed by Andreas (2005) and Andreas and Wang (2006) and Fairall et al. (1994) respectively are incorporated into the regional atmospheric Mesoscale Model version 3.6 (MM5V3) of Pennsylvania State University/National Center for Atmospheric Research (PSU/NCAR) and the coupled atmosphere-sea spray modeling system is applied to simulate a Western Pacific super ty-phoon Ewiniar in 2006. The simulation results demonstrate that sea spray can lead to a significant increase in heat fluxes at the air-sea interface and the simulated typhoon’s intensity. Compared with the results without sea spray,the minimum sea level pressure reduces about 8hPa after taking account of sea spray by Fairall et al.’s parameterization (1994) and about 5hPa by Andreas’ (2005) and Andreas and Wang’s (2006) parameterization at the end of the model integration,while the maximum 10m wind speed increases about 17% and 15% on average,respectively,through the entire simulation time period. Taking sea spray into account also causes significant changes in Tropical Cyclone (TC) structure due to an enhancement of water vapor and heat transferred from the sea sur-face to the air; therefore,the center structure of the typhoon becomes more clearly defined and the wind speed around the typhoon eye is stronger in numerical experiments. The simulations show that different sea spray flux parameterizations make different modi-fications to the TC structure.

关键词： sea spray tropical cyclone flux parameterization numerical simulation

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SPM-IS: An auto-algorithm to acquire a mature soybean phenotype based on instance segmentation

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The Crop Journal 2022年第5期10卷 1412-1423页

作者： Shuai Li Zhuangzhuang Yan Yixin Guo xiaoyan Su Yangyang Cao Bofeng Jiang fei Yang Zhanguo Zhang Dawei Xin Qingshan Chen Rongsheng Zhu College of Engineering Northeast Agricultural UniversityHarbin 150030HeilongjiangChina College of Arts and Sciences Northeast Agricultural UniversityHarbin 150030HeilongjiangChina College of Agriculture Northeast Agricultural UniversityHarbin 150030HeilongjiangChina

Mature soybean phenotyping is an important process in soybean breeding;however, the manual process is time-consuming and labor-intensive. Therefore, a novel approach that is rapid, accurate and highly precise is required to obtain the phenotypic data of soybean stems, pods and seeds. In this research, we propose a mature soybean phenotype measurement algorithm called Soybean Phenotype Measure-instance Segmentation(SPM-IS). SPM-IS is based on a feature pyramid network, Principal Component Analysis(PCA) and instance segmentation. We also propose a new method that uses PCA to locate and measure the length and width of a target object via image instance segmentation. After 60,000 iterations, the maximum mean Average Precision(m AP) of the mask and box was able to reach 95.7%. The correlation coefficients R^(2) of the manual measurement and SPM-IS measurement of the pod length, pod width, stem length, complete main stem length, seed length and seed width were 0.9755, 0.9872, 0.9692, 0.9803,0.9656, and 0.9716, respectively. The correlation coefficients R^(2) of the manual counting and SPM-IS counting of pods, stems and seeds were 0.9733, 0.9872, and 0.9851, respectively. The above results show that SPM-IS is a robust measurement and counting algorithm that can reduce labor intensity, improve efficiency and speed up the soybean breeding process.

关键词： Soybean Feature pyramid network PCA Instance segmentation Deep learning

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The preparation of terephthalic acid by solvent-free oxidation of p-xylene with air over T(p-C1)PPMnC1 and Co(OAc)_2

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Chinese Chemical Letters 2011年第2期22卷 135-138页

作者： Yang Xiao xiaoyan Zhang Qin Bo Wang Ze Tan Can Cheng Guo Wei Deng Zhi Gang Liu He fei Zhang College of Chemistry and Chemical Engineering Hunan UniversityChangsha 410082China

An attempt has been made to prepare terephthalic acid（TPA） by solvent-free oxidation of p-xylene（PX） with air over tetra（pchlorophenylporphinato） manganese chloride（T（p-Cl）PPMnCl） and cobalt *** co-catalysis between T（p-Cl）PPMnCl and Co（OAc）_2 has been discovered under solvent-free *** yield could be increased significantly when T（p-Cl）PPMnCl and Co（OAc）_2 were used *** addition of T（p-Cl）PPMnCl into the reaction mixture over Co（OAc）_2 significantly accelerated the rate-determining step of the oxidation process of PX to *** effect of temperature on reaction was also investigated.

关键词： Terephthalic acid Solvent-free p-Xylene Oxidation Manganese porphyrin Cobalt acetate

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减轻某产品细长管内膛阴阳线腐蚀技术研究

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新技术新工艺 2019年第9期 34-37页

作者：张利峰李欧费晓燕王威吴涛李海杰荆政霖王雅君李松内蒙古北方重工业集团有限公司

某细长管为该产品中的重要零件,其内孔槽线要求进行电解加工成型。通过对电解加工特点的合理利用、制作专用工装以及制定专用工艺等方法,探讨了减轻电解加工后内膛膛线腐蚀的最佳办法,解决了某产品内膛出现“不均匀腐蚀斑”的问题,在成... 详细信息

某细长管为该产品中的重要零件,其内孔槽线要求进行电解加工成型。通过对电解加工特点的合理利用、制作专用工装以及制定专用工艺等方法,探讨了减轻电解加工后内膛膛线腐蚀的最佳办法,解决了某产品内膛出现“不均匀腐蚀斑”的问题,在成品满足生产需要后,可指导细长管的生产实践。

关键词：内孔槽细长管电解加工工装工艺阴极

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高强韧石油钻具调质热处理力学性能研究与应用

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新技术新工艺 2019年第7期 4-7页

作者：侯彪正霍进良费晓燕张利峰赵永光刘淑琴王晏恒王艳超内蒙古北方重工业集团有限公司

针对石油开采难度大的高投入井及故障处理成本高的海上油井,借助兵工企业在材料和工艺技术领域的军工优势,进行高强韧石油钻具调制热处理工艺应用研究。通过对高强韧石油钻具力学性能、晶粒度和疲劳寿命等指标的分析,合理选择高强韧石... 详细信息

针对石油开采难度大的高投入井及故障处理成本高的海上油井,借助兵工企业在材料和工艺技术领域的军工优势,进行高强韧石油钻具调制热处理工艺应用研究。通过对高强韧石油钻具力学性能、晶粒度和疲劳寿命等指标的分析,合理选择高强韧石油钻具材料,规定冶炼方法,控制材料非金属夹杂物和化学成分中的硫、磷含量。经过热处理试验,综合力学性能、金相组织、疲劳试验及扫描电镜分析,确定了满足高强韧石油钻具的最佳材料及热处理工艺方法。结果表明,P钢的各项技术指标满足高强韧石油钻具设计要求,在低应力条件下疲劳寿命更高,是4145H钢石油钻具的十倍以上。采用中频感应调质热处理的工艺方法,晶粒度更细小,综合力学性能更优。

关键词：高强韧石油钻具热处理综合力学性能晶粒度疲劳寿命扫描电镜

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Ferroelectricity of hafnium oxide-based materials:Current status and future prospects from physical mechanisms to device applications

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Journal of Semiconductors 2023年第5期44卷 78-121页

作者： Wanwang Yang Chenxi Yu Haolin Li Mengqi Fan Xujin Song Haili Ma Zheng Zhou Pengying Chang Peng Huang fei Liu xiaoyan Liu Jinfeng Kang School of Integrated Circuits Peking UniversityBeijing 100871China Beijing Advanced Innovation Center for Integrated Circuits Beijing 100871China Key Laboratory of Optoelectronics Technology Ministry of EducationBeijing University of TechnologyBeijing 100124China

The finding of the robust ferroelectricity in HfO_(2)-based thin films is fantastic from the view point of both the fundamentals and the *** this review article,the current research status of the future prospects for the ferroelectric HfO_(2)-based thin films and devices are presented from fundamentals to *** related issues are discussed,which include:1)The ferroelectric characteristics observed in HfO_(2)-based films and devices associated with the factors of dopant,strain,interface,thickness,defect,fabrication condition,and more;2)physical understanding on the observed ferroelectric behaviors by the density functional theory(DFT)-based theory calculations;3)the characterizations of microscopic and macroscopic features by transmission electron microscopes-based and electrical properties-based techniques;4)modeling and simulations,5)the performance optimizations,and 6)the applications of some ferroelectric-based devices such as ferroelectric random access memory,ferroelectric-based field effect transistors,and the ferroelectric tunnel junction for the novel information processing systems.

关键词： ferroelectricity HfO_(2)-based thin films physical mechanism characterization modeling and simulation applications

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Nuclear Aurora kinase A triggers programmed death-ligand 1-mediated immune suppression by activating MYC transcription in triple-negative breast cancer

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Cancer Communications 2021年第9期41卷 851-866页

作者： Shulan Sun Wei Zhou Xiaoxi Li fei Peng Min Yan Yajing Zhan Fan An xiaoyan Li Yunyong Liu Quentin Liu Haozhe Piao Central Laboratory Cancer Hospital of China Medical UniversityDalian Medical University Clinical Oncology CollegeLiaoning Cancer Hospital&InstituteShenyangLiaoning 110042P.R.China Institute of Cancer Stem Cell Dalian Medical UniversityDalianLiaoning 116044P.R.China State Key Laboratory of Oncology in South China Sun Yat-sen University Cancer CenterGuangzhouGuangdong 510060P.R.China Department of Pathology Cancer Hospital of China Medical UniversityLiaoning Cancer Hospital and instituteShenyangLiaoning 110042P.R.China Department of Cancer Prevention and Treatment Cancer Hospital of China Medical UniversityLiaoning Cancer Hospital&InstituteShenyangLiaoning 110042P.R.China Department of Neurosurgery Cancer Hospital of China Medical UniversityLiaoning Cancer Hospital&InstituteShenyangLiaoning 110042P.R.China

Background:Increasing studies have reported that oncogenes regulate components of the immune system,suggesting that this is a mechanism for *** kinase A(AURKA),a serine/threonine kinase,is involved in cell mitosis and is essential for tumor cell proliferation,metastasis,and drug ***,the mechanism by which AURKA is involved in immune response regulation is ***,this study aimed to investigate the role of AURKA in immune regulation in triple-negative breast cancer(TNBC).Methods:Peripheral blood mononuclear cells(PBMCs)were co-cultured with TNBC *** xCELLigence Real-Time Cell Analyzer-MP system was used to detect the killing efficiency of immune cells on TNBC *** expression of immune effector molecules was tested by quantitative real-time polymerase chain reaction(qRT-PCR)to evaluate immune ***,to validate AURKA-regulated immune response in vivo,4T1 murine breast cancer cell line with AURKA overexpression or downregulation was engrafted into BALB/c *** distribution and proportion of immune cells in tumors were further evaluated by immunohistochemistry and flow ***:Downregulation of AURKA in TNBC cells increased immune response by activating CD8^(+)T cell proliferation and *** rather than cytoplasmic AURKA-derived programmed death-ligand 1(PD-L1)expression was independent of its kinase *** investigations showed that nuclear AURKA increased PD-L1 expression via an MYC-dependent ***-L1 overexpression mostly reversed AURKA silencing-induced expression of immune effector molecules,including interleukin-(IL-2),interferon-γ(IFN-γ),and ***,AURKA expression was negatively correlated with the enrichment and activity of tumor-infiltrating CD8^(+)T cells in 4T1 engrafted BALB/c mouse ***:Nuclear AURKA elevated PD-L1 expression via an MYCdependent pathway and contributed to immune evasion in *** targeting nuclear AU

关键词： Aurora kinase A immune evasion immunotherapy MYC programmed death-ligand 1 triplenegative breast cancer

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Adaptive gradient-based source and mask co-optimization with process awareness

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Chinese Optics Letters 2019年第12期17卷 32-37页

作者： Yijiang Shen fei Peng xiaoyan Huang Zhenrong Zhang School of Automation Guangdong University of TechnologyMega Education Center SouthGuangzhou 510006China Guangxi Key Laboratory of Multimedia Communications and Network Technology School of ComputerElectronics and InformationGuangxi UniversityNanning 530004China

We develop a source and mask co-optimization framework incorporating the minimization of edge placement error(EPE)and process variability band(PV Band)into the cost function to compensate simultaneously for the image distortion and the increasingly pronounced lithographic process *** differentiable functions of the EPE and the PV Band are presented,and adaptive gradient methods are applied to break symmetry to escape suboptimal local *** on the initial mask conditions is also *** results demonstrate the efficacy of the proposed source and mask optimization approach in pattern fidelity improvement,process robustness enhancement,and almost unaffected performance with random initial masks.

关键词： optimization process gradient

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Enhancing single-molecule conductance of platinum (Ⅱ) complexes through synergistic aromaticity-assisted structural asymmetry

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Science China Chemistry 2020年第4期63卷 467-474页

作者： Ping Duan Junyang Liu Jin-Yun Wang Kai Qu Shuning Cai fei Wang Lichuan Chen xiaoyan Huang Ruihao Li Jia Shi Qian-Chong Zhang Wenjing Hong Zhong-Ning Chen State Key Laboratory of Structural Chemistry Fujian Institute of Research on the Structure of MatterChinese Academy of SciencesFuzhou 350002China State Key Laboratory of Physical Chemistry of Solid Surfaces Collaborative Innovation Center of Chemistry for Energy Materials(iChEM)NELCollege of Chemistry and Chemical EngineeringXiamen UniversityXiamen 361005China

Seeking the strategies of designing highly conductive molecular structures is one of the core researches in molecular *** asymmetric structure has manifested feasible properties in comprehensive fields, we introduce the structures of asymmetric platinum(Ⅱ) complexes into the charge transport study at single-molecule scale for the first time. The single-molecule conductance measurement results reveal that, in platinum(Ⅱ)-aryloligoynyl structures, the conductance of asymmetrically coordinated complexes is obviously higher than that of the symmetric isomers with the same molecular length, while the conductance is almost identical in symmetric and asymmetric platinum(Ⅱ)-oligoynyl complexes. Theoretical study uncovers that, upon connecting to the oligoynyl structure, the aromatic group effectively extends the π-system of the whole conductive backbone and gathers the HOMO population mainly on the longer oligoynyl ligand, which reduces the energy barrier in electron transport and enhances the conductance through HOMO energy lifting. This result provides feasible strategy for achieving high conductive molecular devices.

关键词： single-molecule conductance organometallic asymmetry conductance enhancement

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Titanium carbide nanosheets with defect structure for photothermal-enhanced sonodynamic therapy

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Bioactive Materials 2022年第2期7卷 409-419页

作者： Guangqiang Li xiaoyan Zhong Xianwen Wang fei Gong Huali Lei Yangkai Zhou Chengfei Li Zhidong Xiao Guoxi Ren Liang Zhang Zhiqiang Dong Zhuang Liu Liang Cheng College of Science State Key Laboratory of Agricultural MicrobiologyHuazhong Agricultural UniversityWuhan430070China Institute of Functional Nano&Soft Materials(FUNSOM) Jiangsu Key Laboratory for Carbon-Based Functional Materials&DevicesSoochow UniversitySuzhou215123China Department of Toxicology School of Public HealthMedical College of Soochow UniversitySuzhou215123China State Key Laboratory of Functional Materials for Informatics Shanghai Institute of Microsystem and Information TechnologyChinese Academy of SciencesShanghai200050China College of Biomedicine and Health College of Life Science and TechnologyHuazhong Agricultural UniversityWuhanHubei430070China

Sonodynamic therapy(SDT)has attracted widespread interest in biomedicine,owing to its novel and noninvasive therapeutic method triggered by ultrasound(US).Herein,the Ti_(3)C_(2) MXene nanosheets(Ti_(3)C_(2) NSs)are developed as good sonosensitizers via a two-step method of chemical exfoliation and high-temperature *** the high-temperature treatment,the oxygen defect of Ti_(3)C_(2) MXene nanosheets(H-Ti_(3)C_(2) NSs)is greatly ***,the electron(e^(-))and hole(h^(+))generated by US can be separated faster due to the improved degree of oxidation,and then the recombination of e^(-)-h^(+)can be prevented with the abundant oxygen defect under US irradiation,which induced the sonodynamic efficiency greatly to improve around 3.7-fold compared with Ti_(3)C_(2) NSs without high-temperature *** PEGylation,the H-Ti_(3)C_(2)-PEG NSs show good stability and *** vitro studies exhibit that the inherent property of mild photothermal effect can promote the endocytosis of H-Ti_(3)C_(2)-PEG NSs,which can improve the SDT *** vivo studies further display that the increased blood supply by the mild photothermal effect can significantly relieve hypoxia in the tumor microenvironment,showing photothermal therapy(PTT)enhanced *** importantly,the H-Ti_(3)C_(2)-PEG NSs can be biodegraded and excreted out of the body,showing no significant long-term *** work develops the defective H-Ti_(3)C_(2) NSs as high-efficiency and safe sonosensitizers for photothermal-enhanced SDT of cancer,extending the biomedical application of MXene-based nanoplatforms.

关键词： Ti_(3)C_(2)MXenes Oxygen defect Sonosensitizers Sonodynamic therapy Biosafety

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