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媒介地理学视角下北京宋庄艺术区的多重地方建构

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地理科学进展 2024年第2期43卷 316-330页

作者：陈晓雪冯健北京大学城市与环境学院北京100871

在社交媒体构建起全方位媒介化社会生活的现实背景和媒介与传播地理学成为地理学研究新方向的理论背景下,论文运用文本分析和深度访谈的质性研究方法,以北京宋庄艺术区为例,探究中国语境下媒介与传播对地方的多重建构。研究发现,政府及... 详细信息

在社交媒体构建起全方位媒介化社会生活的现实背景和媒介与传播地理学成为地理学研究新方向的理论背景下,论文运用文本分析和深度访谈的质性研究方法,以北京宋庄艺术区为例,探究中国语境下媒介与传播对地方的多重建构。研究发现,政府及主流媒体代表国家力量主导的传播领域,为实施地方品牌营造、地方形象重塑和发展战略转型,分别对宋庄艺术区实施了合法化、产业化与商业化三阶段的媒介建构策略。外部公众在社交媒体上对宋庄的媒介建构一方面服从政府塑造的宋庄作为文化艺术高地和打卡旅游地的形象,巩固了政府话语在地方传播和地方代言上的权威地位;另一方面又基于短暂的在地体验揭示出一种与官方话语不同的地方意象。艺术家作为长期生活的内部群体,通过草根和非正式的短视频实践,自下而上地将宋庄建构成一个与其日常生活经验和私人情感密切结合的地方,打破了他者视角对自身主体性与宋庄真实艺术生活的遮蔽。论文从媒介地理学的理论视角通过提供中国艺术区的案例研究,丰富了地方表征与建构的研究成果,同时讨论了媒介地方与现实地方以及不同实践主体之间的互动关系,对理解宋庄的发展特征以及少被关注的中国艺术家的生活境况具有重要意义。

关键词：媒介地理学地方表征地方建构社交媒体宋庄艺术区

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神话与科幻瘟疫叙事的共性研究

绥化学院学报 2022年第6期42卷 63-66页

作者：杨晓雪李媛西华师范大学文学院四川南充637002

神话是过去的科幻,科幻是将来的神话,而瘟疫则是人类历史的重要组成部分。同样以幻想性为基本文体特征的神话和科幻在建塑瘟疫的角色定位、叙述瘟疫的发生机制和抗疫手段这三个方面呈现出跨越时空限制的共通性。暗含了对人类的心灵抚慰... 详细信息

神话是过去的科幻,科幻是将来的神话,而瘟疫则是人类历史的重要组成部分。同样以幻想性为基本文体特征的神话和科幻在建塑瘟疫的角色定位、叙述瘟疫的发生机制和抗疫手段这三个方面呈现出跨越时空限制的共通性。暗含了对人类的心灵抚慰和生命关怀,呈现了人类共同体与自然的动态对话过程,显示了神力与技术相互交织的内在张力。

关键词：神话科幻瘟疫共性隐喻

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Diagnosis and Quantification Strategy of Right-to-Left Shunt caused by Patent Foramen Ovale——Simultaneous Study With Contrast Transcranial Doppler,Contrast Transthoracic and Transesophageal Echocardiography

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Diagnosis and Quantification Strategy of Right-to-Left Shunt...

Pathways to carbon neutrality in the built environment: Phase change materials

中国超声医学工程学会第十四届全国超声心动图学术会议

作者： yang xiaoxue Liu Baomin Wei Yajuan Zhai Nina The Second Affiliated Hospital of Xi’an Jiaotong University

Objectives:The purpose of this study was to compare the accuracy of contrast transcranial doppler ultrasonography(cTCD),contrast transthoracic echocardiography(cTTE) and contrast transesophageal echocardiography(cTEE) in the diagnosis and quantification of right to left shunt(RLS)due to patent foramen ovale,and to define the most suitable diagnostic strategy for its assessment in clinical ***:167 patients with headache,dizziness and cryptogenic stroke were recruited in the Second Affiliated Hospital of Xi’an Jiaotong University from December 2017 to May *** cTCD and cTTE were firstly performed among the patients who underwent routine echocardiography in order to rule out cardiac structural *** them 63 patients underwent further cTEE examination due to suboptimal contrast transthoracic echocardiographic image *** all the patients underwent cTCD,cTTE and cTEE examinations at baseline and Valsalva *** cTTE and cTEE,the severity of RLS was semiquantitatively assessed with images obtained from the four-chamber view by scaling the numbers of microbubbles in the left cardiac *** addition,cTEE examination was performed to record the PFO tunnel length and diameter in bicaval ***-square test was applied to determine the differences of positive rates and shunt detection results among the three *** kappa test was used to assess the concordance in quantifying the severity of the ***,we used Student t-test to calculate the severity of RLS-PFO based on the PFO tunnel length and diameter.P value less than 0.05 was considered statistically ***:We found that the positive detection rate of PFO-RLS was significantly higher at Valsalva maneuver than at rest in all three *** positive detection rate of PFO-RLS in cTCD was significantly higher than ***,there was no significant difference of positive rate between cTTE and *** the assessment of severe PFO-RLS,the cTCD

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Green Carbon 2024年第2期2卷 197-204页

作者： Wenzhu Lin xiaoxue Yao Wen Zhao Yiru Pu Steven Wang Department of Mechanical Engineering City University of Hong KongHong KongChina

Phase change materials(PCMs)are increasingly capturing the spotlight in the realm of building design and construction owing to their capacity to absorb and release thermal energy throughout phase *** review provides a comprehensive overview of PCMs,outlining their properties and applications in improving energy efficiency,comfort,and sustainability in *** delves into various types of PCMs,discussing their selection criteria,integration methods,and their impact on indoor climate and energy *** exploration covers both passive and active PCM systems across diverse building components,including implications for walls,roofs,windows,and floors,and integrated heating,ventilation and air conditioning(HVAC)and solar energy ***,the review addresses challenges associated with PCM implementation in building applications while considering future prospects in this field.

关键词： Phase change material Building Latent heat Energy storage Energy saving

DEAD-box helicase 17(DDX17)protects cardiac function by promoting mitochondrial homeostasis in heart failure

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Signal Transduction and Targeted Therapy 2024年第6期9卷 2774-2790页

作者： Mingjing Yan Junpeng Gao Ming Lan Que Wang Yuan Cao Yuxuan Zheng Yao yang Wenlin Li xiaoxue Yu Xiuqing Huang Lin Dou Bing Liu Junmeng Liu Hongqiang Cheng Kunfu Ouyang Kun Xu Shenghui Sun Jin Liu Weiqing Tang Xiyue Zhang Yong Man Liang Sun Jianping Cai Qing He Fuchou Tang Jian Li Tao Shen The Key Laboratory of Geriatrics Beijing Institute of GeriatricsInstitute of Geriatric MedicineChinese Academy of Medical SciencesBeijing Hospital/National Center of Gerontology of National Health CommissionBeijing 100730China Peking University Fifth School of Clinical Medicine Beijing 100730China Department of Laboratory Medicine Huashan HospitalShanghai Medical CollegeFudan UniversityShanghai 200040China Biomedical Pioneering Innovation Center School of Life SciencesPeking UniversityBeijing 100871China Emergency Center Zhongnan Hospital of Wuhan UniversityWuhan 430071China Department of Cardiology Beijing HospitalNational Center of GerontologyInstitute of Geriatric MedicineChinese Academy of Medical Sciences&Peking Union Medical CollegeBeijing 100730China Graduate School of Peking Union Medical College Beijing 100730China Department of Health Care Beijing HospitalNational Center of GerontologyInstitute of Geriatric MedicineChinese Academy of Medical SciencesBeijing 100730China Peking-Tsinghua Center for Life Sciences Academy for Advanced Interdisciplinary StudiesPeking UniversityBeijing 100871China Department of Pathology and Pathophysiology and Department of Cardiology at Sir Run Run Shaw Hospital Zhejiang University School of MedicineHangzhou 310058China Department of Cardiovascular Surgery Peking University Shenzhen HospitalShenzhen 518036China Experimental Technology Center for Life Sciences at Beijing Normal University Beijing 100875China

DEAD-box helicase 17(DDX17)is a typical member of the DEAD-box family with transcriptional cofactor *** DDX17 is abundantly expressed in the myocardium,its role in heart is not fully *** generated cardiomyocyte-specific Ddx17-knockout mice(Ddx17-cKO),cardiomyocyte-specific Ddx17 transgenic mice(Ddx17-Tg),and various models of cardiomyocyte injury and heart failure(HF).DDX17 is downregulated in the myocardium of mouse models of heart failure and cardiomyocyte ***-specific knockout of Ddx17 promotes autophagic flux blockage and cardiomyocyte apoptosis,leading to progressive cardiac dysfunction,maladaptive remodeling and progression to heart *** of DDX17 expression in cardiomyocytes protects cardiac function under pathological *** studies showed that DDX17 can bind to the transcriptional repressor B-cell lymphoma 6(BCL6)and inhibit the expression of dynamin-related protein 1(DRP1).When DDX17 expression is reduced,transcriptional repression of BCL6 is attenuated,leading to increased DRP1 expression and mitochondrial fission,which in turn leads to impaired mitochondrial homeostasis and heart *** also investigated the correlation of DDX17 expression with cardiac function and DRP1 expression in myocardial biopsy samples from patients with heart *** findings suggest that DDX17 protects cardiac function by promoting mitochondrial homeostasis through the BCL6-DRP1 pathway in heart failure.

关键词： DDX17 homeostasis cardiac

中国省域共同富裕水平的时空演进、地区差异及障碍因素研究

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统计与决策 2024年第7期40卷 22-27页

作者：魏晓雪安徽师范大学经济管理学院安徽芜湖241002

文章首先基于过程性、富裕度、共享性、可持续性四大维度构建了共同富裕评价指标体系;其次,采用熵权-TOPSIS法测度2005—2020年中国30个省份的共同富裕水平;最后,利用核密度估计分析共同富裕水平的时空演进趋势,运用Dagum基尼系数分解... 详细信息

文章首先基于过程性、富裕度、共享性、可持续性四大维度构建了共同富裕评价指标体系;其次,采用熵权-TOPSIS法测度2005—2020年中国30个省份的共同富裕水平;最后,利用核密度估计分析共同富裕水平的时空演进趋势,运用Dagum基尼系数分解地区差异,采用障碍因子诊断模型分析共同富裕的主要障碍因素。研究发现:样本期内中国省域共同富裕水平呈现增长趋势,存在典型的梯度化差异;富裕度水平高于共享性水平、过程性水平和可持续性水平;共同富裕水平整体呈现“东高西低、南高北低”的空间格局;东部、中部和西部地区的内部演进趋势存在异质性,地区间差异是总体差异的主要来源;共同富裕的主要影响因素来自创新驱动领域。

关键词：共同富裕评价体系时空演进差异分解障碍因素

基于精化预积分的GNSS/IMU/视觉多源融合定位方法

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北京航空航天大学学报 2024年第6期50卷 2026-2032页

作者：贾晓雪赵冬青肖国锐杨显赐杨朝永赖路广信息工程大学地理空间信息学院郑州450001

针对传统预积分算法固定地球重力值和忽略地球自转的问题,提出一种考虑地球自转和重力变化的惯性测量单元(inertial measurement unit, IMU)预积分算法。参照高精度捷联惯性导航解算的动力学模型,在IMU预积分动力学模型的姿态更新中引... 详细信息

针对传统预积分算法固定地球重力值和忽略地球自转的问题,提出一种考虑地球自转和重力变化的惯性测量单元(inertial measurement unit, IMU)预积分算法。参照高精度捷联惯性导航解算的动力学模型,在IMU预积分动力学模型的姿态更新中引入地球自转角速率,速度和位置更新中引入由地球自转引起的科里奥利加速度,同时将由载体位置引起的地球重力变化及时反馈至预积分算法中,详细推导了引入地球自转和重力变化后预积分算法的具体过程,实现对传统预积分模型的精化。并将精化的预积分算法应用于基于紧耦合全球导航卫星系统(global navigation satellite system, GNSS)/IMU/视觉多源融合系统中,实测实验结果表明:利用精化的预积分模型可使系统预积分的模型误差有效减小,显著提升多源融合系统整体的定位定姿精度,其中系统定位精度提升32.41%,航向角精度提升4.23%。

关键词： IMU预积分地球自转重力变化图优化多源融合定位

Research on Three-Dimensional Simulation of the Internal Arc Gear Skiving

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Mechanical Engineering Science 2024年第1期6卷 35-40页

作者： Xiaoqiang WU Rui XUE Erkuo GUO Dongzhou JIA Taiyan GONG Zengrong LI Haijun yang xiaoxue LI Xin JIANG Shuai DING Yong LIU Shitian LI School of Mechanical and Traffic Engineering Ordos Institute of TechnologyOrdosInner Mongolia017000China Tianjin TANHAS Technology Co. LTDTianjin301600China School of Mechanical Engineering Jiangsu UniversityZhenjiangJiangsu212002China College of Mechanical Engineering and Automation Liaoning University of TechnologyJinzhouLiaoning121001China Inner Mongolia Ruite Precision Mould Co. LTD.The First Machinery GroupBaotouInner Mongolia014030China Inner Mongolia University Of Technology College Of Energy And Power EngineeringHohhotInner Mongolia010051China

Aiming at the problems that the simulation accuracy which is reduced due to the simplification of the model,a three-dimensional simulation method based on solid modeling is being *** analyzing the motion relationship and positional relationship between the caries knife and the workpiece,the coordinate system of the caries machining was *** the MATLAB software,the cutting edge model and the blade sweeping surface model of the boring cutter are sequentially *** operation is performed on the blade swept surface formed by the tooth cutter teeth with time t and the workpiece tooth geometry as well as the undeformed three-dimensional chip geometry model and the instantaneous cogging geometry model are obtained at different *** the compare between gear end face simulation tooth profile and the theoretical inner arc tooth profile,we verified the accuracy and rationality of the proposed method.

关键词： gear skiving undeformed three-dimensional chips solid modeling

重组人CC16蛋白改善慢性阻塞性肺疾病模型小鼠肺功能及其机制

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中国病理生理杂志 2023年第10期39卷 1789-1795页

作者：郭民李婷杨晓雪高睿栗馨洋王海龙庞敏山西医科大学实验动物中心山西太原030001 山西医科大学第一医院呼吸与危重症医学科呼吸疾病防治与基础研究山西省重点实验室山西太原030001 山西医科大学基础医学研究中心山西晋中030600

目的:探究重组人CC16蛋白(rhCC16)对慢性阻塞性肺疾病(COPD)模型小鼠肺功能的改善作用及其机制。方法:40只BALB/c雄性小鼠随机均分为对照组、COPD模型组、COPD+PBS组和COPD+rhCC16组,每组10只。采用被动吸烟6月法制备COPD模型小鼠,从熏... 详细信息

目的:探究重组人CC16蛋白(rhCC16)对慢性阻塞性肺疾病(COPD)模型小鼠肺功能的改善作用及其机制。方法:40只BALB/c雄性小鼠随机均分为对照组、COPD模型组、COPD+PBS组和COPD+rhCC16组,每组10只。采用被动吸烟6月法制备COPD模型小鼠,从熏烟16周开始,在熏烟前2 h用2.5μg/g rhCC16或等体积PBS对熏烟小鼠进行滴鼻干预,制备COPD+rhCC16组或COPD+PBS组。造模及干预结束后检测各组小鼠肺功能;HE染色观察各组小鼠肺组织形态结构;RT-qPCR法检测各组小鼠肺组织P16和P21的mRNA表达;免疫组织化学法检测各组小鼠肺组织P16、P21、衰老相关β-半乳糖苷酶(SA-β-Gal)、p-P38及磷酸化细胞外信号调节激酶1/2(p-ERK1/2)蛋白表达情况。结果:与对照组相比,COPD模型组小鼠0.3秒内用力呼气容积(FEV0.3)/用力肺活量(FVC)比值降低(P<0.05),气道阻力增加(P<0.05),肺顺应性降低(P<0.05);小鼠肺泡壁破裂塌陷,肺泡大小不均匀,多呈不规则扩大,管腔狭窄,管壁增厚;小鼠肺组织P16和P21的mRNA表达水平显著升高(P<0.05),小鼠肺组织P16、P21、SA-β-Gal、p-P38和p-ERK1/2蛋白表达量升高(P<0.05);与COPD模型组相比,rhCC16干预组小鼠各项肺功能指标均有缓解(P<0.05),肺组织病理损伤减轻,小鼠肺组织P16和P21 mRNA表达水平降低(P<0.05),小鼠肺组织P16、P21、SA-β-Gal、p-P38和p-ERK1/2蛋白表达量降低(P<0.05);PBS组各项指标与COPD组相似。结论:rhCC16可能通过P38 MAPK/ERK1/2信号通路减轻COPD小鼠肺组织衰老,进而改善COPD模型小鼠肺功能。

关键词：慢性阻塞性肺疾病肺功能 CC16蛋白衰老 P38 MAPK/ERK1/2信号通路