检索结果-南通市图书馆

Initial Experience of nIR-II Fluorescence Imaging-Guided Surgery in Foot and Ankle Surgery

Engineering 2024年第9期40卷 19-27页

作者： xiaoxiao fan.jie y.n. Huwei ni Qiming Xia Xiaolong Liu Tianxiang Wu Lin Li Paras n.Prasad Chao Liu Hui Lin Jun Qian Department of General Surgery Sir Run Run Shaw HospitalSchool of MedicineZhejiang UniversityHangzhou 310016China Centre for Optical and Electromagnetic Research&International Research Center for Advanced Photonics College of Optical Science and EngineeringZhejiang UniversityHangzhou 310058China Department of Orthopedics Sir Run Run Shaw HospitalSchool of MedicineZhejiang UniversityHangzhou 310016China Institute for Lasers Photonicsand BiophotonicsDepartment of ChemistryState University of New YorkBuffaloNY 14260-3000USA Zhejiang Engineering Research Center of Cognitive Healthcare Sir Run Run Shaw HospitalSchool of MedicineZhejiang UniversityHangzhou 310016China College of Biomedical Engineering and Instrument Science Zhejiang UniversityHangzhou 310027China

Optical imaging in the second near-infrared(nIR-II;900-1880 nm)window is currently a popular research topic in the field of biomedical *** study aimed to explore the application value of nIR-II fluorescence imaging in foot and ankle surgeries.A lab-established nIR-II fluorescence surgical navigation system was developed and used to navigate foot and ankle surgeries which enabled obtaining more high-spatial-frequency information and a higher signal-to-background ratio(SBR)in nIR-II fluorescence images compared to nIR-I fluorescence images;our result demonstrates that nIR-II imaging could provide higher-contrast and larger-depth images to *** types of clinical application scenarios(diabetic foot,calcaneal fracture,and lower extremity trauma)were included in this *** the nIR-II fluorescence imaging technique,we observed the ischemic region in the diabetic foot before morphological alterations,accurately determined the boundary of the ischemic region in the surgical incision,and fully assessed the blood supply condition of the ***-II fluorescence imaging can help surgeons precisely judge surgical margins,detect ischemic lesions early,and dynamically trace the perfusion *** believe that portable and reliable nIR-II fluorescence imaging equipment and additional functional fluorescent probes can play crucial roles in precision surgery.

关键词： Second near-infrared fluorescence imaging Foot and ankle surgery Indocy.n.ne green Imaging-guided surgery

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Hot-band absorption of indocy.n.ne green for advanced anti-stokes fluorescence bioimaging

引用

Light(Science & Applications) 2021年第10期10卷 1877-1888页

作者： Jing Zhou xiaoxiao fan Di Wu jie Liu yuhuang Zhang Zikang ye Dingwei Xue Mubin He Liang Zhu Zhe Feng Andrey.n.Kuzmin Wen Liu Paras n.Prasad Jun Qian State Key Laboratory of Modern Optical Instrumentations Centre for Optical and Electromagnetic ResearchCollege of Optical Science and EngineeringInternational Research Center for Advanced PhotonicsZhejiang UniversityHangzhou 310058China Sir Run-Run Shaw Hospital School of MedicineZhejiang UniversityHangzhou 310016China Key Laboratory of Flexible Electronics(KLOFE)Institute of Advanced Materials(IAM) Nanjing Tech University(Nanjing Tech)Nanjing 211800China Department of Chemistry Zhejiang UniversityHangzhou 310058China Interdisciplinary Institute of neuroscience and Technology(ZIInT) College of Biomedical Engineering and Instrument ScienceZhejiang UniversityHangzhou 310027China Institute for Lasers Photonicsand BiophotonicsDepartment of ChemistryUniversity at BuffaloState University of New YorkBuffaloNY 14260USA Key Laboratory of Optical Information Detection and Display Technology of Zhejiang Zhejiang Normal UniversityJinhua 321004China

Bright anti-Stokes fluorescence(ASF)in the first near-infrared spectral region(nIR-I,800 nm–900 nm)under the excitation of a 915 nm continuous wave(CW)laser,is observed in Indocy.n.ne Green(ICG),a dye approved by the Food and Drug Administration for clinical *** dependence of fluorescence intensity on excitation light power and temperature,together with fluorescence lifetime measurement,establish this ASF to be originated from absorption from a thermally excited vibrational level(hot-band absorption),as shown in our experiments,which is stronger than the upconversion fluorescence from widely-used rare-earth ion doped *** test the utility of this ASF nIR-I probe for advanced bioimaging,we successively apply it for biothermal sensing,cerebral blood vessel tomography and blood stream ***,in combination with L1057 nanoparticles,which absorb the ASF of ICG and emit bey.n. 1100 nm,these two probes generate multi-mode images in two fluorescent channels under the excitation of a single 915 nm CW *** channel is used to monitor two overlapping organs,urinary system&blood vessel of a live mouse,while the other shows urinary system *** in intraoperative real-time monitoring,such multi-mode imaging method can be beneficial for visual guiding in anatomy of the urinary system to avoid any accidental injury to the surrounding blood vessels during surgery.

关键词： absorption excitation anatomy

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

由超拍电子伏特加速器产生的超高能伽马射线气泡

引用

Science Bulletin 2024年第4期69卷 449-457页

作者： LHAASO Collaboration Zhen Cao Chuandong Gao Cong Li Ruo-yu Liu Ruizhi y.n. 不详 Key Laboratory of Particle Astrophyics&Experimental Physics Division&Computing Center Institute of High Energy PhysicsChinese Academy of SciencesBeijing 100049China University of Chinese Academy of Sciences Beijing 100049China TIAnFU Cosmic Ray Research Center ChengduChina Institute of Frontier and Interdisciplinary Science Shandong UniversityQingdao 266237China School of Astronomy and Space Science Nanjing UniversityNanjing 210023China University of Science and Technology of China Hefei 230026China

We report the detection of aγ-ray bubble spanning at least 100deg2 in ultra-high energy(UHE)up to a few PeV in the direction of the star-forming region Cy.n.s X,imply.n. the presence super PeVatron(s)accelerating protons to at least 10 PeV.A log-parabola form with the photon indexΓ(E)=(2.71±0.02)+(0.11±0.02)×log10(E/10 TeV)is found fitting the gamma-ray energy spectrum of the bubble *** sources,“hot spots”correlated with very massive molecular clouds,and a quasi-spherical amorphousγ-ray emitter with a sharp central brightening are observed in the *** the core of~0.5°,spatially associating with a region containing massive OB association(Cy.n.s OB2)and a microquasar(Cy.n.s X-3),as well as previously reported multi-TeV sources,an enhanced concentration of UHEγ-rays is observed with 2 photons at energies above 1 *** general feature of the bubble,the morphology,and the energy spectrum,are reasonably reproduced by the assumption of a particle accelerator in the core,continuously injecting protons into the ambient medium.

关键词： Cosmic rays γ-rays Interstellar medium Star cluster

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Evidence for particle acceleration approaching PeV energies in the W51 complex

引用

Science Bulletin 2024年第18期69卷 2833-2841页

作者： LHAASO Collaboration Zhen Cao F.Aharonian Axikegu y.X.Bai y.W.Bao D.Bastieri X.J.Bi y.J.Bi W.Bian A.V.Bukevich Q.Cao W.y.Cao Zhe Cao J.Chang J.F.Chang A.M.Chen E.S.Chen H.X.Chen Liang Chen Lin Chen Long Chen M.J.Chen M.L.Chen Q.H.Chen S.Chen S.H.Chen S.Z.Chen T.L.Chen y.Chen n.Cheng y.D.Cheng M.y.Cui S.W.Cui X.H.Cui y.D.Cui B.Z.Dai H.L.Dai Z.G.Dai Danzengluobu X.Q.Dong K.K.Duan J.H.fan y.Z.fan J.fang J.H.fang K.fang C.F.Feng H.Feng L.Feng S.H.Feng X.T.Feng y.Feng y.L.Feng S.Gabici B.Gao C.D.Gao Q.Gao W.Gao W.K.Gao M.M.Ge L.S.Geng G.Giacinti G.H.Gong Q.B.Gou M.H.Gu F.L.Guo X.L.Guo y.Q.Guo y.y.Guo y.A.Han M.Hasan H.H.He H.n.He J.y.He y.He y.K.Hor B.W.Hou C.Hou X.Hou H.B.Hu Q.Hu S.C.Hu D.H.Huang T.Q.Huang W.J.Huang X.T.Huang X.y.Huang y.Huang X.L.Ji H.y.Jia K.Jia K.Jiang X.W.Jiang Z.J.Jiang M.Jin M.M.Kang I.Karpikov D.Kuleshov K.Kurinov B.B.Li C.M.Li Cheng Li Cong Li D.Li F.Li H.B.Li H.C.Li Jian Li jie Li K.Li S.D.Li W.L.Li W.L.Li X.R.Li Xin Li y.Z.Li Zhe Li Zhuo Li E.W.Liang y.F.Liang S.J.Lin B.Liu C.Liu D.Liu D.B.Liu H.Liu H.D.Liu J.Liu J.L.Liu M.y.Liu R.y.Liu S.M.Liu W.Liu y.Liu y.n.Liu Q.Luo y.Luo H.K.Lv B.Q.Ma L.L.Ma X.H.Ma J.R.Mao Z.Min W.Mitthumsiri H.J.Mu y.C.nan A.neronov L.J.Ou P.Pattarakijwanich Z.y.Pei J.C.Qi M.y.Qi B.Q.Qiao J.J.Qin A.Raza D.Ruffolo A.Sáiz M.Saeed D.Semikoz L.Shao O.Shchegolev X.D.Sheng F.W.Shu H.C.Song yu.V.Stenkin V.Stepanov y.Su D.X.Sun Q.n.Sun X.n.Sun Z.B.Sun J.Takata P.H.T.Tam Q.W.Tang R.Tang Z.B.Tang W.W.Tian C.Wang C.B.Wang G.W.Wang H.G.Wang H.H.Wang J.C.Wang Kai Wang Kai Wang L.P.Wang L.y.Wang P.H.Wang R.Wang W.Wang X.G.Wang X.y.Wang y.Wang y.D.Wang y.J.Wang Z.H.Wang Z.X.Wang Zhen Wang Zheng Wang D.M.Wei J.J.Wei y.J.Wei T.Wen C.y.Wu H.R.Wu Q.W.Wu S.Wu X.F.Wu y.S.Wu S.Q.Xi J.Xia G.M.Xiang D.X.Xiao G.Xiao y.L.Xin y.Xing D.R.Xiong Z.Xiong D.L.Xu R.F.Xu R.X.Xu W.L.Xu L.Xue D.H.y.n.J.Z.y.n.T.y.n.C.W.y.n. C.y.y.n. F.y.n. F.F.y.n. L.L.y.n. M.J.y.n. R.Z.y.n. W.X.y.n. y.H.yao Z.G.yao L.Q.y.n.n.y.n.X.H.you Z.y.you y.H.yu Q.yuan H.yue H.D.Zeng T.X.Zeng W.Zeng M.Zha B.B.Zhang F.Zhang H.Zhang 不详 Key Laboratory of Particle Astrophysics&Experimental Physics Division&Computing Center Institute of High Energy PhysicsChinese Academy of SciencesBeijing 100049China University of Chinese Academy of Sciences Beijing 100049China TIAnFU Cosmic Ray Research Center ChengduChina Dublin Institute for Advanced Studies 31 Fitzwilliam Place2 DublinIreland Max-Planck-Institut for nuclear Physics P.O.Box 103980Heidelberg 69029Germany School of Physical Science and Technology&School of Information Science and Technology Southwest Jiaotong UniversityChengdu 610031China School of Astronomy and Space Science Nanjing UniversityNanjing 210023China Center for Astrophysics Guangzhou UniversityGuangzhou 510006China Tsung-Dao Lee Institute&School of Physics and Astronomy Shanghai Jiao Tong UniversityShanghai 200240China Institute for nuclear Research of Russian Academy of Sciences Moscow 117312Russia Hebei normal University Shijiazhuang 050024China University of Science and Technology of China Hefei 230026China State Key Laboratory of Particle Detection and Electronics China Key Laboratory of Dark Matter and Space Astronomy&Key Laboratory of Radio Astronomy Purple Mountain ObservatoryChinese Academy of SciencesNanjing 210023China Research Center for Astronomical Computing Zhejiang LaboratoryHangzhou 311121China Key Laboratory for Research in Galaxies and Cosmology Shanghai Astronomical ObservatoryChinese Academy of SciencesShanghai 200030China School of Physics and Astronomy Yunnan UniversityKunming 650091China Key Laboratory of Cosmic Rays(Tibet University) Ministry of EducationLhasa 850000China national Astronomical Observatories Chinese Academy of SciencesBeijing 100101China School of Physics and Astronomy(Zhuhai)&School of Physics(Guangzhou)&Sino-French Institute of nuclear Engineering and Technology(Zhuhai) Sun Yat-sen UniversityZhuhai 519000&Guangzhou 510275GuangdongChina Institute of Frontier and Interdisciplinary Science Shandong UniversityQingdao 266237China APC UniversitéParis Cité

Theγ-ray emission from the W51 complex is widely acknowledged to be attributed to the interaction between the cosmic rays(CRs)accelerated by the shock of supernova remnant(SnR)W51C and the dense molecular clouds in the adjacent star-forming region,***,the maximum acceleration capability of W51C for CRs remains *** on observations conducted with the Large High Altitude Air Shower Observatory(LHAASO),we report a significant detection ofγrays emanating from the W51 complex,with energies from 2 to 200 *** LHAASO measurements,for the first time,extend theγ-ray emission from the W51 complex bey.n. 100 TeV and reveal a significant spectrum bending at tens of *** combining the"π^(0)-decay bump"featured data from Fermi-LAT,the broadbandγ-ray spectrum of the W51 region can be well-characterized by a simple pp-collision *** observed spectral bending feature suggests an exponential cutoff at~400 TeV or a power-law break at~200 TeV in the CR proton spectrum,most likely providing the first evidence of SnRs serving as CR accelerators approaching the PeV ***,two young star clusters within W51B could also be theoretically viable to produce the most energeticγrays observed by *** findings strongly support the presence of extreme CR accelerators within the W51 complex and provide new insights into the origin of Galactic CRs.

关键词： UHE c-ray Cosmic rays SnR W51C Star clusters

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

影响肘管综合征尺神经前置临床效果的因素

引用

中国矫形外科杂志 2024年第4期32卷 326-331页

作者：康乐范琳琳崔建强胡宇宁徐林曲军杰滨州医学院烟台附属医院山东烟台264100

[目的]探讨影响肘管综合征尺神经前置术疗效的影响因素。[方法]对2018年12月—2021年6月行手术治疗的89例肘管综合征患者资料进行回顾性分析。采用顾氏分级评价临床状态,依据末次随访时患者顾氏评级将患者分为优良组和不佳组,采用单因... 详细信息

[目的]探讨影响肘管综合征尺神经前置术疗效的影响因素。[方法]对2018年12月—2021年6月行手术治疗的89例肘管综合征患者资料进行回顾性分析。采用顾氏分级评价临床状态,依据末次随访时患者顾氏评级将患者分为优良组和不佳组,采用单因素比较的二元逻辑回归分析探讨影响肘管综合征尺神经前置术疗效的影响因素。[结果]所有患者均顺利完成尺神经松解前置术,未出现切口感染、不愈合等不良并发症。术后随访时间18~36个月,平均26.5个月。末次随访根据顾氏肘管综合征功能评定标准评价恢复情况,优46例,良25例,可11例,差7例,优良率为79.8%。评定为优和良的患者共71例划入良好组;评定为可和差的患者共18例划入不佳组,单因素比较表明:不佳组的糖尿病史[是/否,(10/61)vs(7/11),P=0.017],肘部外伤史[(5/66)vs(10/8),P0.05)。逻辑回归结果表明:糖尿病(OR=4.652,95%CI 1.091~19.832,P=0.038)、肘部外伤史(OR=10.111,95%CI 2.252~45.398,P=0.003)、术前疾病程度(OR=4.193,95%CI 1.138~15.456,P=0.031)是肘管综合征尺神经前置临床效果不佳的独立危险因素。[结论]糖尿病、肘部外伤史、术前疾病程度重是肘管综合征尺神经前置临床效果不佳的危险因素,应引起临床医生的重视。

关键词：肘管综合征尺神经卡压尺神经前置术预后影响因素

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Synthesis, Crystal Structure and non-covalent Interactions Analysis of novel n-Substituted Thiosemicarbazone

引用

Chemical Research in Chinese Universities 2019年第3期35卷 471-477页

作者： ZHAnG Xing HUAnG jie ZHAnG yu QI fan WAnG Sifan SOnG Jirong Shaanxi Key Laboratory of Physico-inorganic Chemistry School of Chemical Engineering Northwest UniversityXi'an 710069P.R.China Ministry of Science and Technology the Palace MuseumBeijing 100009P.R.China

()*￡-1 -(4-Fluorobenzylidene)^l-(4-ethylphenyl)thiosemicarbazone was synthesized via the reaction of 4-(4-ethylphenyl)thiosemicarbazide and 4-fluorobenzaldehyde. The title compound was characterized by FTIR, and 13C nMR, mass spectrometry and elemental analysis techniques. Structural property of the title compound was displayed by the X-ray single crystal diffraction. The title compound crystallized in triclinic space group Pl witli a=0.6494(4) nm,a=0.7971(5) nm, c=1.5492( 10) nm,a=83.690( 11)°,β=84.185(10)。γ=84.348(11)。molecular formula Ci6H16Fn3S,Mr=301.39,V=0.7868(9) nm^3, Z=2, Dc=1.272 g/cm……3,^000)=316,“=0.213 mm-1, 5=1.02, 7?=O.O513, and cw7[Z>2o(Z)]=0.1662. The intennolecular interactions in the crystal structure were explained using the Hirshfeld surface and their associated two-dimensional fingerprint plots. The title compound showed C-H-S(l-x,-y,-z) and nH(1-y,-z) intermolecular interactions, and formed the supramolecular self-assemblies through R2^2(12) and R2^2(8) ring motifs. Shape index and curvediiess were performed to further understand some unique weak interactions, for instance, the weakπ…π stacking contacts in molecular structure witli difierent characteristic regions. Besides, the reduced density gradient(RDG) function provided a real-space function for discussing non-covalent interactions within molecule, such as hydrogen bonds, weak van der Waals interactions and attractive or repulsive effects.

关键词： novel n-substituted thiosemicarbazone non-covalent interaction Reduced desity gradient(RDG) function Hirshfeld surface analysis

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Optimization of performance of the KM2A full array using the Crab nebula

引用

Chinese Physics C 2024年第6期48卷 169-178页

作者：曹臻 F.Aharonian 安琪阿西克古白云翔包逸炜 D.Bastieri 毕效军毕玉江蔡金庭曹晴曹文羽曹喆常进常劲帆陈尚明陈恩生陈亮陈林陈龙陈明君陈玛丽陈起辉陈素弘陈天禄陈阳程宁程耀东崔明阳崔树旺崔晓红崔昱东戴本忠代洪亮戴子高单增罗布 D.della Volpe 董绪强段凯凯樊军辉范一中方军方堃冯存峰封莉冯少辉丰晓婷冯有亮 S.Gabici 高博高川东高林青高启高卫高伟康葛茂茂耿利斯 G.Giacinti 龚光华苟全补顾旻皓郭福来郭晓磊郭义庆郭莹莹韩毅昂何会海贺昊宁何佳银何新波何钰 M.Heller 贺远强侯博文侯超侯贤胡红波胡铨胡世聪黄代绘黄天奇黄文俊黄性涛黄晓渊黄勇黄志成季筱璐贾焕玉贾康江琨姜晓巍姜泽军金敏康明铭柯通 D.Kuleshov.K.Kurinov 李兵兵李澄李骢李丹李飞李海波李会财李华阳李军李剑李捷李凯李文龙李文莲李秀荣李昕李一卓李哲黎卓梁恩维梁云峰林苏杰刘冰刘成刘栋刘虎刘海东刘佳刘江来刘金艳刘茂元柳若愚刘四明刘伟刘怡刘以农鲁睿罗晴吕洪魁马伯强马玲玲马欣华毛基荣闵振 W.Mitthumsiri 穆慧君南云程 A.neronov 区子维庞彬宇 P.Pattarakijwanich 裴致远齐孟尧祁业情乔冰强秦家军 D.Ruffolo A.Sáiz D.Semikoz 邵澄宇邵琅 O.Shchegolev 盛祥东舒富文宋慧超 yu.V.Stenkin V.Stepanov 苏扬孙秦宁孙晓娜孙志斌谭柏轩唐庆文唐泽波田文武王超王昌贝王广威王洪光王惠惠王建成汪凯王利苹王玲玉王培汉王冉王为王祥高王祥玉王阳王玉东王岩谨王忠海王仲翔王振王铮韦大明魏俊杰魏永健文韬吴超勇吴含荣武莎吴雪峰吴雨生席邵强夏捷夏君集项光漫肖迪泫肖刚辛广广辛玉良邢祎熊峥徐东莲徐仁峰徐仁新徐伟立薛良闫大海颜景志颜田杨朝文杨帆杨冯帆杨何文杨佳盈杨莉莉杨明洁杨睿智杨深邦姚玉华姚志国叶一锰尹丽巧尹娜游晓浩游智勇于艳红袁强岳华曾厚敦曾婷轩曾玮查敏张彬彬张丰张海明张恒英张建立张丽霞张力张鹏飞张佩佩张瑞张少博张少如张寿山张潇张笑鹏张云峰张毅张勇赵兵赵静赵雷赵立志赵世平郑福周斌周浩周佳能周猛周平周荣周勋秀祝成光祝凤荣朱辉朱科军左雄 LHAASO Collaboration Key Laboratory of Particle Astrophyics&Experimental Physics Division&Computing Center Institute of High Energy PhysicsChinese Academy of SciencesBeijing 100049China University of Chinese Academy of Sciences Beijing 100049China Tianfu Cosmic Ray Research Center Chengdu 610000China Dublin Institute for Advanced Studies 31 Fitzwilliam Place2 DublinIreland Max-Planck-Institut for nuclear Physics P.O.Box 10398069029 HeidelbergGermany State Key Laboratory of Particle Detection and Electronics China University of Science and Technology of China Hefei 230026China School of Physical Science and Technology&School of Information Science and Technology Southwest Jiaotong UniversityChengdu 610031China School of Astronomy and Space Science Nanjing UniversityNanjing 210023China Center for Astrophysics Guangzhou UniversityGuangzhou 510006China Hebei normal University Shijiazhuang 050024China Key Laboratory of Dark Matter and Space Astronomy&Key Laboratory of Radio Astronomy Purple Mountain ObservatoryChinese Academy of SciencesNanjing 210023China Tsung-Dao Lee Institute&School of Physics and Astronomy Shanghai Jiao Tong UniversityShanghai 200240China Key Laboratory for Research in Galaxies and Cosmology Shanghai Astronomical ObservatoryChinese Academy of SciencesShanghai 200030China Key Laboratory of Cosmic Rays(Tibet University) Ministry of EducationLhasa 850000TibetChina national Astronomical Observatories Chinese Academy of SciencesBeijing 100101China School of Physics and Astronomy(Zhuhai)&School of Physics(Guangzhou)&Sino-French Institute of nuclear Engineering and Technology(Zhuhai) Sun Yat-sen UniversityZhuhai 519000&Guangzhou 510275China School of Physics and Astronomy Yunnan UniversityKunming 650091China Département de Physique nucléaire et Corpusculaire Facultéde SciencesUniversitéde Genève24 Quai Ernest Ansermet1211 GenevaSwitzerland Institute of Frontier and Interdisciplinary Science Shandong UniversityQingdao 266237China APC Universit'e Paris Cit'eCNRS/IN2P3CEA/IRFUObservat

The full array of the Large High Altitude Air Shower Observatory(LHAASO)has been in operation since July *** its kilometer-square array(KM2A),we optimized the selection criteria for very high and ultrahigh energyγ-rays using data collected from August 2021 to August 2022,resulting in an improvement in significance of the detection in the Crab nebula of approximately 15%,compared with that of previous *** the implementation of these new selection criteria,the angular resolution was also significantly improved by approximately 10%at tens of *** aspects of the full KM2A array performance,such as the pointing error,were also calibrated using the Crab *** resulting energy spectrum of the Crab nebula in the energy range of 10-1000 TeV are well fitted by a log-parabola model,which is consistent with the previous results from LHAASO and other experiments.

关键词： γ-ray Crab nebula significance

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Enhancing charge storage of O-doped perovskite fluorides via in-situ electrochemical oxidation for high-performance potassium-ion capacitors

引用

Journal of Materials Science & Technology 2023年第27期158卷 111-120页

作者： Jing Zhao Zicheng Cai yue fan y.n.n Wang yu Song jie Liu Shuangwen Li Di Guo Xiaoxia Liu Department of Chemistry Northeastern UniversityShenyang 110819China School of Resources and Civil Engineering Northeastern UniversityShenyang 110819China national-local Joint Engineering Research Center of High-efficient Exploitation Technology for Refractory Iron Ore Resources Shenyang 110819China School of Materials Engineering North China Institute of Aerospace EngineeringLangfang 065000China

Potassium ion capacitors(PICs)are regarded as promising large-scale aqueous energy storage ***,due to the poor K^(+)transport kinetics and the structural instability of the cathode materials,the key issues of limited energy density and poor cyclic stability are obstacles to the in-depth growth of ***,a novel O-doped perovskite fluoride is demonstrated via an in-situ electrochemical oxidation strategy as the cathode for PICs,introducing additional defects that improve the capacitance and facilitate the reaction kinetics of the *** the electrochemical oxidation process,it is discovered that the perovskite fluoride crystal tends to transform into disordered O-doped KMnF 3(K_(x)MnF_(y)O_(z)),realizing a structural reconstruction at the electrode material/electrolyte *** First-principles calculations based on density functional theory(DFT)are performed to confirm that the improved electrical conduc-tivity and low ionic adsorption energy may be ascribed to the substitution of oxygen for *** obtained K_(1.14)MnF_(1.17)O_(1.26) cathode achieves a high specific capacitance of 694 F g^(-1) at 1 A g^(-1),as well as high capacitance retention of 91.3%after 10,000 charge/discharge cycles in mild K_(2)SO_(4) *** study provides an effective strategy to improve the capacitive performance of perovskite fluoride cathode materials in electrochemical energy storage.

关键词： Perovskite fluorides O-doped Potassium-ion capacitors Charge storage mechanism

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

HITS-CLIP reveals sex-differential RnA binding and alterative splicing regulation of SRm160 in Drosophila

引用

Journal of Molecular Cell Biology 2019年第2期11卷 170-181页

作者： Chen Qiu yu Zhang yu-jie fan Ting-Lin Pang y.n.Su Shuai Zhan y.n.-Zhen Xu CAS Key Laboratory of Insect Developmental and Evolutionary Biology Institute of Plant Physiology and Ecology Chinese Academy of Sciences Shanghai 200032 China University of Chinese Academy of Sciences Shanghai 200032 China CAS Center for Excellence in Molecular Cell Science Chinese Academy of Sciences Shanghai 200032 China CAS Center for Excellence in Molecular Plant Sciences Chinese Academy of Sciences Shanghai 200032 China

Serine/arginine (SR)-rich proteins are critical for the regulation of alternative splicing (AS), which generates multiple mRnA isoforms from one gene and provides protein diversity for cell differentiation and tissue development. Genetic evidence suggests that Drosophila genital-specific overexpression of SR-related nuclear matrix protein of 160 kDa (SRml60), an SR prot&n with a PWI RnA-binding motif, causes defective development only in male flies and results in abnonnal male genital structures and abnormal testis. However, the molecular characterization of SRm160 is limited. Using the high-throughput sequencing of RnA isolated by crosslinking immunoprecipitation (HITS-CLIP) method in two sex-specific embry.n.c cell lines, S2 from the male and Kc from the female, we first identified the genome-wide RnA-binding characteristics of SRm160, which preferred binding to the exonic tri-nucleotide repeats GCA and AAC. We then validated this binding through both in vitro gel-shift assay and in vivo splicing of minigenes and found that SRm160 level affects AS of many transcripts. Furthermore, we identified 492 differential binding sites (DBS) of SRm160 vary.n. between the two sex-specific cell *** these DBS-containing genes, splicing factors were highly enriched, including transformer, a key regulator in the sex determination cascade. Analyses of fly mutants demonstrated that the SRm160 level affects AS isoforms of transformer. These findings shed crucial light on SRm160's RnA-binding specificity and regulation of AS in Drosophila sex determination and development.

关键词： SR protein SRm160 HITS-CLIP RnA-binding motif Drosophila sexual development

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Polymyxin for the treatment of intracranial infections of extensively drug-resistant bacteria in children after neurosurgical operation

引用

World Journal of Pediatrics 2020年第5期16卷 528-532页

作者： Jing ye Lin-Hua Tan Zhi-Peng Shen y.n.Song yu Deng-Ming Lai jie fan Qiang Shu Department of Surgical ICU Children's HospitalZhejiang University School of MedicineNational Clinical Research Center For Child HealthHangzhou 310052China Department of neurosurgery Children's HospitalZhejiang University School of MedicineNational Clinical Research Center For Child HealthHangzhou 310052China Department of Infectious Diseases Sir Run Run Shaw HospitalZhejiang University School of MedicineHangzhou 310003China Department of neonatal Surgery Children's HospitalZhejiang University School of MedicineNational Clinical Research Center For Child HealthHangzhouZhejiangChina Department of Surgery University of Pittsburgh School of MedicinePittsburghPAUSA Research and Development Veterans Affairs Pittsburgh Healthcare SystemPittsburghPAUSA McGowan Institute for Regenerative Medicine University of PittsburghPittsburghPAUSA Department of Thoracic and Cardiovascular Surgery Children's HospitalZhejiang University School of MedicineNational Clinical Research Center For Child HealthNo.3333 Bin-Sheng RoadBin-Jiang DistrictHangzhou 310052China

Background Increased meningitis caused by extensively drug-resistant bacillary presents a significant challenge in antibiotic *** aim of our study was to evaluate the efficacy and safety of polymyxin in the treatment of post-neurosurgical meningitis due to the extensively drug-resistant bacillary in *** We performed a retrospective study on post-neurosurgical meningitis caused by the extensively drug-resistant bacillary in children,who were treated with polymyxin for≥3 *** Among five post-neurosurgical meningitis cases that were included,the children were infected by Acinetobacter baumannii(n=3),Klebsiella pneumonia(n=l),and Pseudomonas aeruginosa(n=1).The drug susceptibility test showed that they were extensively drug-resistant *** patients received intravenous polymyxin *** children received intravenous combined with intraventricular injection of polymyxin *** patient infected by Klebsiella pneumonia eventually died of septic *** serious adverse effects of polymyxin were *** Polymyxin is a safe and effective therapy for post-neurosurgical,multidrug-resistant bacillary meningitis in children.

关键词： Drug resistance Meningitis neurosurgical procedures Polymyxin

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：