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A new interacting capillary bundle model on the multiphase flow in micropores of tight rocks

Petroleum Science 2024年第2期21卷 1099-1112页

作者： Wen-Quan Deng Tian-bo Liang Wen-zhong Wang Hao Liu Jun-Lin Wu Fu-Jian Zhou National Key Laboratory of Petroleum Resources and Engineering China University of Petroleum(Beijing)Beijing102249China

Surfactants are widely used in the fracturing fluid to enhance the imbibition and thus the oil recovery rate. However, current numerical models cannot capture the physics behind capillary imbibition during the wettability alteration by surfactants. Although the interacting capillary bundle(ICB) model shows potential in characterizing imbibition rates in different pores during wettability alteration, the existing ICB models neglect the influence of wettability and viscosity ratio on the imbibition behavior, making it difficult to accurately describe the oil-water imbibition behavior within the porous media. In this work,a new ICB mathematical model is established by introducing pressure balance without assuming the position of the leading front to comprehensively describe the imbibition behavior in a porous medium under different conditions, including gas-liquid spontaneous imbibition and oil-water *** the pore size distribution of a tight rock is known, this new model can predict the changes of water saturation during the displacement process in the tight rock, and also determine the imbibition rate in pores of different sizes. The water saturation profiles obtained from the new model are validated against the waterflooding simulation results from the CMG, while the imbibition rates calculated by the model are validated against the experimental observations of gas-liquid spontaneous imbibition. The good match above indicates the newly proposed model can show the water saturation profile at a macroscopic scale while capture the underlying physics of the multiphase flow in a porous medium at a microscopic scale. Simulation results obtained from this model indicate that both wettability and viscosity ratio can affect the sequence of fluid imbibition into pores of different sizes during the multiphase flow, where less-viscous wetting fluid is preferentially imbibed into larger pores while more-viscous wetting fluid tends to be imbibed into smaller pores. Fur

关键词： Imbibition Multiphase flow Tight rock Interacting capillary bundle model Wettability

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A converged ubiquitin-proteasome pathway for the degradation of TOC and TOM tail-anchored receptors

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Journal of Integrative Plant Biology 2024年第5期66卷 1007-1023页

作者： Meijing Yang Shuai chen Shey-Li Lim Lang Yang Jia Yi zhong Koon Chuen Chan Zhizhu Zhao Kam-bo Wong Junqi Wang boon Leong Lim School of Biological Sciences University of Hong KongPokfulam 999077Hong KongChina Department of Biology Southern University of Science and TechnologyShenzhen 518055China School of Biomedical Engineering Shenzhen UniversityShenzhen 518060China School of Life Sciences The Chinese Universityof Hong KongShatin 999077HongKongChina State Key Laboratory of Agrobiotechnology The Chinese University of Hong KongShatin 999077Hong KongChina HKU Shenzhen Institute of Research and Innovation Shenzhen 518052China

In plants,thousands of nucleus-encoded proteins translated in the cytosol are sorted to chloroplasts and mitochondria by binding to specific receptors of the TOC(translocon on the outer chloroplast membrane)and the TOM(translocon on the outer mitochondrial membrane)complexes for import into those *** degradation pathways for these receptors are ***,we discovered a converged ubiquitin-proteasome pathway for the degradation of Arabidopsis thaliana TOC and TOM tail-anchored *** receptors are ubiquitinated by E3 ligase(s)and pulled from the outer membranes by the AAA+adenosine triphosphatase CDC48,after which a previously uncharacterized cytosolic protein,transmembrane domain(TMD)-binding protein for tail-anchored outer membrane proteins(TTOP),binds to the exposed TMDs at the C termini of the receptors and CDC48,and delivers these complexes to the 26S proteasome.

关键词： 26S proteasome CDC48 SP1 TOC TOM ubiquitination

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The pathogenesis of chronic subdural hematoma in the perspective of neomembrane formation and related mechanisms

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BIOCELL 2024年第6期48卷 889-896页

作者： MINGYUE HUANG JUNFEI DAI XIANLIANG zhong JIN WANG JIANzhong XU bo DU School of Medicine Southern University of Science and TechnologyShenzhen518055China Department of Emergency Shenzhen People’s HospitalThe Second Clinical Medical College of Jinan UniversityThe First Affiliated Hospital of Southern University of Science and TechnologyShenzhen518055China

Chronic subdural hematoma(CSDH)is a disease characterized by capsuled blood products that progressively occupy the intracranial space,causing intracranial hypertension and compression in the *** frequently occurs in all demographics,especially in the elderly,but the pathogenesis of CSDH remains *** this review,we discuss the origin,development,and current treatment strategies of *** theﬁrst time,we analyzed the cellular and molecular compositions of hematoma membranes with a focus on neomembrane formation,a complex early-stage interactive event in hematoma *** hypothesize that in patients with CSDH,dural border cells(DBCs)might be induced to synthesize collagen or serum proteins might accumulate at the dura and arachnoid layers at the site of injury,thereby encapsulating the *** formation may trigger inﬂammatory responses after subdural hemorrhage,promotingﬁbroblast-involved extracellular matrix(ECM)deposition and aberrant angiogenesis within the outer ***,ECM deposition and angiogenesis mutually inﬂuence each other and are modulated by inﬂammatory *** illustrating the complex and interactive mechanism of neomembrane formation,we aim to provide a novel insight into CSDH pathogenesis and propose directions for future research as well as advancements in treatment strategies for this disease.

关键词： Chronic subduralhematoma Inflammation Angiogenesis Extracellular matrix Hyperfibrinolysis

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Mechanical Janus lattice with plug-switch orientation

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Theoretical & Applied Mechanics Letters 2024年第1期14卷 23-26页

作者： Yupei Zhang Jiawei zhong Zhengcai Zhao Ruiyu Bai Yanqi Yin Yang Yu bo Li State Key Laboratory for Manufacturing System EngineeringShaanxi Key Laboratory of Intelligent Robots School of Mechanical Engineering Xi’an Jiaotong UniversityXi’an 710049China Qian Xuesen Honors College Xi’an Jiaotong UniversityXi’an 710049China

In recent years,materials with asymmetric mechanical response properties(mechanical Janus materials)have been found possess numerous potential applications,*** absorption and vibration *** this study,we propose a novel mechanical Janus lattice whose asymmetric mechanical response can be switched in orientation by a *** finite element analysis and experimental verification,this lattice exhibits asymmetric displacement responses to symmetric ***,with such a plug structure inside,individual lattices can switch the orientation of asymmetry and thus achieve reprogrammable design of a mechanical structure with chained *** reprogrammable asymmetry of this material will offer multiple functions in design of mechanical metamaterials.

关键词： Janus Non-reciprocity Programmability Mechanical metamaterial

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Dimensional regulation in gigantic molybdenum blue wheels featuring{(W)Mo_(5)}motifs for enhanced proton conductivity

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Nano Research 2024年第9期17卷 8261-8268页

作者： Yu-Lun Wu Jing Du Hai-Ying Zhang Ming-Jun Hou Qiao-Yue Li Wei-Chao chen Kui-Zhan Shao bo Zhu Chao Qin Xin-Long Wang zhong-Min Su Key Laboratory of Polyoxometalate and Reticular Material Chemistry of Ministry of Education Department of ChemistryNortheast Normal UniversityChangchun 130024China Hebei Key Laboratory of Organic Functional Molecules National Demonstration Center for Experimental Chemistry EducationTesting and Analysis CenterCollege of Chemistry and Materials ScienceHebei Normal UniversityShijiazhuang 050024China State Key Laboratory of Supramolecular Structure and Materials Institute of Theoretical ChemistryCollege of ChemistryJilin UniversityChangchun 130021China

Dimensional regulation in polyoxometalates is an effective strategy during the design and synthesis of polyoxometalates-based high proton conductors,but it is not available to ***,the precise regulation of dimensionality has been realized in an unprecedented gigantic molybdenum blue wheel family featuring pentagonal{(W)Mo5}motifs through optimizing the molar ratio of Mo/W,including[Gd_(2)Mo_(124)W_(14)O_(422)(H_(2)O)62]38-(0D-{Mo_(124)W_(14)},1),[Mo_(126)W_(14)O441(H_(2)O)51]^(70-)(1D-{Mo_(126)W_(14)}n,2),and[Mo_(124)W_(14)O_(430)(H_(2)O)50]60-(2D-{Mo_(124)W_(14)}n,3).Such important{(W)Mo5}structural motif brings new reactivity into gigantic Mo blue *** are different numbers and sites of{Mo2}defects in each wheel-shaped monomer in 1-3,which leads to the monomers of 2 and 3 to form 1D and 2D architectures via Mo-O-Mo covalent bonds driven by{Mo2}-mediated H_(2)O ligands substitution process,respectively,thus achieving the controllable dimensional *** expected,the proton conductivity of 3 is 10 times higher than that of 1 and 1.7 times higher than that of *** continuous proton hopping sites in 2D network are responsible for the enhanced proton conductivity with lower activation *** study highlights that this dimensional regulation approach remains great potential in preparing polyoxometalates-based high proton conductive materials.

关键词： polyoxometalate molybdenum blue wheels Mo/W mixed-addenda polyoxometalates dimensional regulation proton conduction

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A nano-sheet graphene-based enhanced thermal radiation composite for passive heat dissipation from vehicle batteries

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Nano Materials Science 2024年第4期6卷 443-455页

作者： Ji-Xiang Wang Christopher Salmean Jiaxin Li Chaojie Lei Jun Li Mingliang zhong bo Qi Yufeng Mao Hebei Key Laboratory of Man-machine Environmental Thermal Control Technology and Equipment Hebei Vocational University of Technology and Engineering College of Electrical Energy and Power EngineeringYangzhou University Department of Mechanical and Aerospace Engineering The Hong Kong University of Science and Technology Taizhou Wavexploration Energy Ltd. Department of Electrical and Computer Engineering University of Toronto China Academy of Launch Vehicle Technology Beijing Sino-Spark Technology Co. Ltd. School of Environmental Science and Engineering Suzhou University of Science and Technology Institute of Optics and Electronics Chinese Academy of Sciences National Key Laboratory of Optical Field Manipulation Science and Technology Chinese Academy of Sciences

In response to thermal runaway(TR) of electric vehicles, recent attention has been focused on mitigation strategies such as efficient heat dredging in battery thermal management. Thermal management with particular focus on battery cooling has been becoming increasingly significant. TR usually happened when an electric vehicle is unpowered and charged. In this state, traditional active battery cooling schemes are disabled, which can easily lead to dangerous incidents due to loss of cooling ability, and advanced passive cooling strategies are therefore gaining importance. Herein, we developed an enhanced thermal radiation material, consisting of ～1 μm thick multilayered nano-sheet graphene film coated upon the heat dissipation surface, thereby enhancing thermal radiation in the nanoscale. The surface was characterized on the nanoscale, and tested in a battery-cooling *** found that the graphene-based coating's spectral emissivity is between 91 % and 95 % in the mid-infrared region, and thermal experiments consequently illustrated that graphene-based radiative cooling yielded up to15.1 % temperature reduction when compared to the uncoated analogue. Using the novel graphene surface to augment a heat pipe, the temperature reduction can be further enlarged to 25.6 %. The new material may contribute to transportation safety, global warming mitigation and carbon neutralization.

关键词： Battery thermal management Nano-sheet graphene Functional material Passive cooling Thermal radiation

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Molecular mechanism of a coastal cyanobacterium Synechococcus *** 7002 adapting to changing phosphate concentrations

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Marine Life Science & Technology 2024年第3期6卷 562-575页

作者： Qiao-Wei Sun Yu Gao Jordan Wang Fei-xue Fu cheng-Wen Yong Shuang-Qing Li Hai-Long Huang Wei-zhong chen Xin-Wei Wang Hai-bo Jiang School of Marine Sciences Ningbo UniversityNingbo 315211China Southern Marine Science and Engineering Guangdong Laboratory(Zhuhai) Zhuhai 519080China School of Life Sciences Central China Normal UniversityWuhan 430079China Department of Biological Sciences University of Southern CaliforniaLos AngelesCA 90089USA

Phosphorus concentration on the surface of seawater varies greatly with different environments,especially in *** molecular mechanism by which cyanobacteria adapt to fluctuating phosphorus bioavailability is still *** this study,transcriptomes and gene knockouts were used to investigate the adaptive molecular mechanism of a model coastal cyanobacterium Synechococcus *** 7002 during periods of phosphorus starvation and phosphorus recovery(adding sufficient phosphorus after phosphorus starvation).The findings indicated that phosphorus deficiency affected the photosynthesis,ribosome synthesis,and bacterial motility pathways,which recommenced after phosphorus was *** more,most of the metabolic pathways of cyanobacteria were enhanced after phosphorus recovery compared to the control which was kept in continuous phosphorus replete *** on transcriptome,54 genes potentially related to phosphorusdeficiency adaptation were selected and knocked out individually or in *** was found that five mutants showed weak growth phenotype under phosphorus deficiency,indicating the importance of the genes(A0076,A0549-50,A1094,A1320,A1895)in the adaptation of phosphorus *** mutants were found to grow better than the wild type under phosphorus deficiency,suggesting that the products of these genes(A0079,A0340,A2284–86)might influence the adaptation to phosphorus *** analysis revealed that cyanobacteria exposed to highly fluctuating phosphorus concentrations have more sophisticated phosphorus acquisition *** results elucidated that Synechococcus *** 7002 have variable phosphorus response mechanisms to adapt to fluctuating phosphorus concentration,providing a novel perspective of how cyanobacteria may respond to the complex and dynamic environments.

关键词： Synechococcus sp PCC 7002 Phosphorus fluctuation Cyanobacteria ・Gene knockout Molecular mechanism

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Finite-temperature ductility-brittleness and electronic structures of Al_(n)Sc(n=1,2 and 3)

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Rare Metals 2024年第8期43卷 3974-3989页

作者： Xue-Qian Wang Ying Zhao Hao-Xuan Liu Shu-chen Sun Hong-bo Yang Jia-Min zhong Gan-Feng Tu Song Li Yu-Dong Zhang Claude Esling Hai-Le Yan Liang Zuo Key Laboratory for Anisotropy and Texture of Materials(Ministry of Education) School of Material Science and EngineeringNortheastern UniversityShenyang 110819China School of Metallurgy Northeastern UniversityShenyang 110819China Rare Earth Functional Materials(Xiong'an)Innovation Center Co. Ltd.Xiong'an 071700China Laboratoire d'étude des Microstructures et de Mécanique des Matériaux(LEM3) Unikersitéde Lorraine57045MetzFrance

Finite-temperature ductility-brittleness and electronic structures of Al_(3)Sc,Al_(2)Sc and AlSc are studied comparatively by first-principles calculations and ab initio molecular *** show that Al_(3)Sc and Al_(2)Sc are brittle at both ground state and finite temperatures,while AlSc possesses a significantly superior *** ground state,AlSc is ductile from Pugh's and Poisson's criteria,while it is brittle in Pettifor's *** ductility of all Al_(3)Sc,Al_(2)Sc and AISc improves greatly with the elevated ***,the Cauchy pressure of AlSc undergoes a transition from negative to *** T>600 K,AlSc is unequivocally classified as ductile from all criteria *** all compounds,the Al-Al bond originated from s-p and p-p orbital hybridizations,and the Al-Sc bond dominated by p-d covalent hybridization,are the first and second strongest chemical bonds,*** explain the difference in mechanical properties,the mean bond strength(MBS)is introduced in this *** weaker Al-Al bond in AlSc,leading to a smaller MBS,could be the origin of the softer elastic stiffness and superior intrinsic *** longer length of the Al-Al bond in AlSc is responsible for its weaker bond ***,the enhanced metallicity of the Al-Al bond in AlSc would also contribute to its exceptional *** longer length of the Al-Al bond in AISc is responsible for its weaker bond ***,the enhanced metallicity of the Al-Al bond in AlSc would also contribute to its exceptional ductility.

关键词： Al-Sc Target materials Intrinsic ductility Finite-temperature elastic constant First-principles calculation

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High-capacity device-independent quantum secure direct communication based on hyper-encoding

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Fundamental Research 2024年第4期4卷 851-857页

作者： Hui Zeng Ming-Ming Du Wei zhong Lan Zhou Yu-bo Sheng College of Science Nanjing University of Posts and TelecommunicationsNanjing 210023China College of Electronic and OpticalEngineering &College ofFlexible Electronics(Future Technology)Nanjing University of Posts and TelecommunicationNanjing 210023China Institute of Quantum Information and Technology Nanjing University of Posts and TelecommunicationsNanjing 210003China

Quantum secure direct communication(QSDC)can directly transmit secret messages through quantum channel without ***-independent(DI)QSDC guarantees the message security relying only on the observation of the Bell-inequality violation,but not on any detailed description or trust of the devices'inner *** with conventional QSDC,DI-QSDC has relatively low secret message *** increase DI-QSDC's secret messages capacity,we propose a high-capacity DI-QSDC protocol based on the hyper-encoding *** total message leakage rate of our DI-QSDC protocol only relies on the most robust degree of *** provide the numerical simulation of its secret message capacity altered with the communication *** work serves as an important step toward thefurther development of DI-QSDC systems.

关键词： Quantum cryptography Device-independent Quantum secure direct communication Hyper-encoding Hyperentangled Bell state measurement Secret message capacity

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High Hydrostatic Pressure Exacerbates Bladder Fibrosis through Activating Piezo1

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当代医学科学（英文） 2024年第4期44卷 718-725页

作者： bo-lang DENG Dong-xu LIN Zhi-peng LI Kang LI Peng-yu WEI Chang-cheng LUO Meng-yang ZHANG Quan ZHOU Zheng-long YANG zhong chen Department and Institute of Urology Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430030China Department of Rehabilitation Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430030China School of Mechanical Science and Engineering Huazhong University of Science and TechnologyWuhan 430074China

Objective:Bladder outlet obstruction(boO)results in significant fibrosis in the chronic stage and elevated bladder ***1 is a type of mechanosensitive(MS)channel that directly responds to mechanical *** identify new targets for intervention in the treatment of boO-induced fibrosis,this study investigated the impact of high hydrostatic pressure(HHP)on Piezo1 activity and the progression of bladder ***:Immunofluorescence staining was conducted to assess the protein abundance of Piezo1 in fibroblasts from obstructed rat *** fibroblasts were cultured under normal atmospheric conditions(0 cmH2O)or exposed to HHP(50 cmH2O or 100 cmH2O).Agonists or inhibitors of Piezol,YAP1,and ROCK1 were used to determine the underlying ***:The Piezo1 protein levels in fibroblasts from the obstructed bladder exhibited an elevation compared to the control *** significantly promoted the expression of various pro-fibrotic factors and induced proliferation of ***,the protein expression levels of Piezol,YAP1,ROCK1 were elevated,and calcium influx was increased as the pressure *** effects were attenuated by the Piezol inhibitor *** Piezo1 activator Yoda1 induced the expression of pro-fibrotic factors and the proliferation of fibroblasts,and elevated the protein levels of YAP1 and ROCK1 under normal atmospheric conditions in ***,these effects could be partially inhibited by YAP1 or ROCK ***:The study suggests that HHP may exacerbate bladder fibrosis through activating Piezo1.

关键词： Piezo1 bladder outlet obstruction fibrosis high hydrostatic pressure

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