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Research on internal gravity waves in the Martian atmosphere based on Tianwen-1 and Mars Global Surveyor occultation data

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Earth and Planetary Physics 2024年第6期8卷 890-898页

作者： Luo Xiao CunYing Xiao Xiong Hu ZeWei Wang xiaoqi wu Institute for Frontiers in Astronomy and Astrophysics Beijing Normal UniversityBeijing 102206China School of Physics and Astronomy Beijing Normal UniversityBeijing 100875China State Key Laboratory of Space Weather National Space Science CenterChinese Academy of SciencesBeijing 100045China Key Laboratory of Science and Technology on Environmental Space Situation Awareness National Space Science CenterChinese Academy of SciencesBeijing 100190China

Internal gravity waves(IGWs)are critical in driving Martian atmospheric motion and *** study investigates Martian IGWs by using high-resolution data from China’s Tianwen-1 mission and the National Aeronautics and Space Administration’s Mars Global Surveyor(MGS)by the radio occultation(RO)*** IGW parameters,such as vertical and horizontal wavelengths,intrinsic frequency,and energy density,are extracted based on vertical temperature profiles from the Martian surface to~50 km *** reveal that the Martian IGWs are predominantly small-scale waves,with vertical wavelengths between 6 and 13 km and horizontal wavelengths extending to thousands of *** waves propagate almost vertically and exhibit low intrinsic frequencies close to the inertial frequency,with the characteristic of low-frequency inertial ***-1 data indicate stronger IGW activity,higher energy density,and less dissipation than MGS data in the northern ***,MGS data in the southern hemisphere show higher buoyancy frequencies and lower vertical wavelengths,suggesting more stable atmospheric conditions conducive to IGW *** extracted IGW characteristics can enhance our understanding of the atmospheric dynamics on Mars and contribute valuable information for parameterization in global circulation models.

关键词： internal gravity waves Mars Tianwen-1 Mars Global Surveyor radio occultation

The scientific connotation of oil and gas formations under deep fluids and organic-inorganic interaction

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Science China Earth Sciences 2019年第3期62卷 507-528页

作者： Quanyou LIU Dongya ZHU Qingqiang MENG Jiayi LIU xiaoqi wu Bing ZHOU Qi FU Zhijun JIN State Key Laboratory of Shale Oil and Gas Enrichment Mechanisms and Effective Development Structure & Sedimentary Reservoir Laboratory Petroleum Exploration & Production Research InstituteSINOPEC Department of Earth and Atmospheric Sciences University of Houston

As a relatively stable craton block in the earth system, the petroliferous basin is influenced by the evolution of the earth system from the early development environment of source rocks, hydrocarbon formation, and reservoir dissolution to hydrocarbon accumulation or destruction. As a link between the internal and external factors of the basin, deep fluids run through the whole process of hydrocarbon formation and accumulation through organic-inorganic interaction. The nutrients carried by deep fluids promote the bloom of hydrocarbon-generating organisms and extra addition of carbon and hydrogen source, which are beneficial to the development of high-quality source rock and enhancement of the hydrocarbon generation potential. The energy carried by the deep fluid promotes the early maturation of the source rock and facilitates the hydrocarbon generation by activation and hydrogenation in high-mature hydrocarbon sources. The dissolution alteration of carbonate rocks and clastic reservoirs by CO_2-rich deep fluids improves the deep reservoir space, thus extending the oil and gas reservoir space into greater depth. The extraction of deeply retained crude oil by deep supercritical CO_2 and the displacement of CH_4 in shale have both improved the hydrocarbon fluidity in deep and tight reservoirs. Simultaneously, the energy and material carried by deep fluids(C, H, and catalytic substances) not only induce inorganic CH_4 formation by Fischer-Tropsch(F-T) synthesis and "hydrothermal petroleum" generation from organic matter by thermal activity but also cause the hydrothermal alteration of crude oil from organic sources. Therefore, from the perspective of the interaction of the earth's sphere, deep fluids not only input a significant amount of exogenous C and H into sedimentary basins but also improve the reservoir space for oil and gas, as well as their enrichment and accumulation efficiencies.

关键词： Organic-inorganic interaction Deep fluid Hydrocarbon generation from hydrogenation Dissolution alteration Displacement

The first extra-large helium-rich gas field identified in a tight sandstone of the Dongsheng Gas Field,Ordos Basin,China

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Science China Earth Sciences 2022年第5期65卷 874-881页

作者： Weilong PENG Quanyou LIU Ying ZHANG Huichong JIA Dongya ZHU Qingqiang MENG xiaoqi wu Shang DENG Yongsheng MA State Key Laboratory of Shale Oil and Gas Enrichment Mechanisms and Effective Development Beijing 100083China Petroleum Exploration and Production Research Institute SINOPECBeijing 100083China Exploration and Production Research Institute SINOPEC North China BranchZhengzhou 450006China Ma Yongsheng’s Laboratory Beijing 100083China SINOPEC Company Limited Beijing 100728China

Helium gas is a scarce but important strategic resource,which is usually associated with natural ***,only one extra-large helium-rich gas field has been found in China:the Hetianhe Gas Field in the Tarim *** paper reports a new example,the Dongsheng Gas Field(DGF)in the Ordos *** this study,92 natural gas samples from the DGF were analyzed for helium content and isotope composition using isotope mass *** natural gas samples were found to have an average helium content of 0.133%,with 65(70.7%)of the samples having a helium content of 0.1%or *** on the proven natural gas reserves of the DGF,the proven geological helium reserves were calculated to be 1.96×10^(8)m^(3),suggesting that it represents the first extra-large helium-rich natural gas reservoir to be hosted in tight sandstone in *** ^(3)He/^(4)He ratios of 5 natural gas samples from the DGF are within the range of 3.03×10^(−8)–3.44×10^(−8).Therefore,the helium in the gas field is thought to be of typical crustal origin and to have formed in the granitic basement that is rich in uranium and *** accumulation of helium-rich natural gas was controlled by regional tectonic *** along the fault connecting the reservoir with the basement caused release of the helium gas,which entered the overlying strata along the fault and accumulated with conventional hydrocarbon *** on the structural background and the distribution of helium source rocks in the Ordos Basin,the main helium source rocks with high exploration potential are located in deep strata within the north and middle parts of the basin.

关键词： Helium gas Granitic basement Radiogenesis Dongsheng Gas Field Ordos Basin

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Epigenetic regulation of phosphodiesterase 4d in restrictive cardiomyopathy mice with cTnI mutations

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Science China(Life Sciences) 2020年第4期63卷 563-570页

作者： Weian Zhao xiaoqi wu Zhiyuan Wang Bo Pan Lifei Liu Lingjuan Liu Xupei Huang Jie Tian Department of Cardiology Heart CentreChildren’s Hospital of Chongqing Medical UniversityMinistry of Education Key Laboratory of Child Development and DisordersKey Laboratory of Pediatrics in ChongqingChongqing International Science and Technology Cooperation Center for Child Development and DisordersChongqing 400014China Department of anesthesiology The Children’s Hospital of Chongqing Medical UniversityChongqing 400014China Department of Biomedical Science Charlie E.Schmidt College of MedicineFlorida Atlantic UniversityBoca Raton 33414USA

Epigenetic regulations play an important role in disease *** this study,we have investigated epigenetic regulations in restrictive cardiomyopathy mice with cTnI 193 His *** results demonstrated that phosphodiesterase(PDEs)4d was down-regulated in the heart of these *** studies showed that the epigenetic modifications were associated with enhanced acetylation of histone 3 lysine 4 and lysines 9,whereas tri-methylation of histone 3 lysine 4,were decreased in histones near the PDE4d gene promoter *** binding levels of histone transmethylase SMYD1 and histone deacetylase HDAC1 were increased in the gene promoter regions in cTnI193 His transgenic *** immune-fluorescent labeling we found an evidence of cTnI existence in the nucleus of cardiomyocytes and Western blotting further confirmed that both wild type and mutated cTnI could be detected in the cell nucleus of the ***,an interaction between cTnI and SMYD1,or cTnI and HDAC1 was *** of the mutated cTnI in cultured cardiomyocytes reduced the expression of *** data suggest that the decrease of PDE4d expression in RCM mice caused by cTnI mutations may be related to epigenetic regulation,i.e.,histone acetylation and methylation,and cTnI might be involved in this procedure via an interaction with HDAC1 and SMAD1 in the hearts.

关键词： phosphodiesterase epigenetics histone modifications restrictive cardiomyopathy cardiac troponinⅠ

Distributions and accumulation mechanisms of helium in petroliferous basins

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Science China Earth Sciences 2024年第10期67卷 3143-3168页

作者： Pengpeng LI Quanyou LIU Dongya ZHU Di ZHU Zheng ZHOU xiaoqi wu Qingqiang MENG Jiahao LV Yu GAO Institute of Energy Peking UniversityBeijing 100871China Northwest Institute of Eco-Environment and Resources Chinese Academy of SciencesLanzhou 730000China Petroleum Exploration&Production Research Institute SINOPECBeijing 102206China Energy Research Institute Qilu University of Technology(Shandong Academy of Sciences)Jinan 250014China Lancaster Environment Centre Lancaster UniversityLA14YQUK Institute of Geology and Geophysics Chinese Academy of SciencesBeijing 100029China University of Chinese Academy of Sciences Beijing 100049China

Helium is an irreplaceable strategic mineral resource, and commercial helium-rich gas fields(He>0.1%) worldwide are typically discovered serendipitously during hydrocarbon exploration efforts. According to an analysis of 75 helium-rich gas fields and 1048 natural gas samples worldwide, helium in natural gas generally exhibits “scarce”, “accompanying”, and“complex” properties, and helium-rich gas fields often occur at depths 1%). However, geological reserves in the former two types of gas fields are mainly in the range of 10^(7)–10^(11)m^(3), whereas in the latter, they are only in the range of 10^(5)–10^(7)m^(3). There are nevertheless notable disparities in the genesis and migration patterns between helium and gaseous hydrocarbons. Helium necessitates carriers(such as formation water, hydrocarbon fluids, N_(2), mantle-derived fluids, etc.) during both accumulation and long-distance migration processes, where migration conduits are not confined to sedimentary strata, and may extend to the basin's basement, lower crust, and even lithospheric mantle. However, the accumulation conditions of both helium and gaseous hydrocarbons are generally considered equivalent. The presence of gaseous hydrocarbons facilitates both the rapid exsolution of helium within helium-containing fluids and subsequent efficient aggregation in gaseous hydrocarbons, while both reduce helium diffusion and diminish escape flux. In terms of caprock, gypsum, salt, and thick shale as sealing layers contribute to the long-term preservation of helium over geological timescales. Large helium-rich gas fields, predominantly crust-derived gas fields, are primarily concentrated in uplifted zones of ancient cratonic basins and their peripheries. Based on a diagram of the He concentration versus He/N_(2) ratio, crust-derived helium fields can be categorized as basement, combined basement-s

关键词： Helium resource Geochemical characteristics Helium source rock Helium supply pattern Accumulation mechanism Determination of favorable zones

3-Methyladenine potentiates paclitaxel-induced apoptosis and phosphorylation of cyclin-dependent kinase 1 at thr161 in nasopharyngeal carcinoma cell

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BIOCELL 2024年第5期48卷 861-872页

作者： xiaoqi wu YECHUAN HE YEQIN YUAN XIAN TAN LIN ZHU DANLING WANG BINYUAN JIANG Hengyang Medical School University of South ChinaHengyang421001China Institute for Future Sciences University of South ChinaChangsha410008China Medical Research Center The Affiliated Changsha Central HospitalHengyang Medical SchoolUniversity of South ChinaChangsha410004China Department of Clinical Laboratory The Affiliated Changsha Central HospitalHengyang Medical SchoolUniversity of South ChinaChangsha410004China

Background:Nasopharyngeal carcinoma(NPC)exhibits a significant prevalence in the southern regions of China,and paclitaxel(PTX)is frequently employed as a medication for managing advanced ***,drug resistance is typically accompanied by a poor *** the synergistic potential of combining multiple chemotherapeutic agents may represent a promising avenue for optimizing treatment ***:This study investigated whether 3-Methyladenine(3-MA)could potentiated the effect of PTX and its potential molecular *** were divided into the following categories:Negative control(NC)with the solvent dimethyl sulfoxide(DMSO,0.5%v/v),PTX(400 nM),3-MA(4 mM),and PTX(400 nM)+3-MA(4 mM).The viability of NPC cells was assessed using both the cell counting kit-8(CCK-8)assay and the colony formation *** observation was performed to identify morphological cell *** cytometry was used to assess cell cycle status,mitochondrial membrane potential(MMP),and apoptotic *** blotting was conducted to quantify the protein ***:3-MA enhanced PTX-specific inhibition of NPC cell ***,either alone or in combination with 3-MA,caused cell cycle halt at the G2/M phase in the majority of NPC cells,and the combination treatment of PTX with 3-MA induced a higher rate of NPC cell death compared to PTX *** blotting results revealed the combination of PTX with 3-MA heightened activation of cyclin-dependent kinase 1(CDK1),a key molecule in shifting cells from mitotic arrest to apoptosis,led to a reduction in Myeloid Cell Leukemia 1(MCL-1)expression and an increase in Poly(ADP-ribose)polymerase(PARP)***:The concurrent administration of PTX with 3-MA effectively enhances PTX’s inhibitory impact on NPC and activates the apoptosis signal regulated by CDK1.

关键词： Nasopharyngeal carcinoma Paclitaxel 3-Methyladenine Cell cycle Apoptosis

Geochemical Characteristics and Genetic Types of Natural Gas in the Xinchang Gas Field, Sichuan Basin, SW China

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Acta Geologica Sinica(English Edition) 2017年第6期91卷 2200-2213页

作者： wu xiaoqi LIU Quanyou LIU Guangxiang WANG Ping LI Huaji MENG Qingqiang CHEN Yingbin ZENG Huasheng wuxi Research Institute of Petroleum Geology Petroleum Exploration and Production Research InstituteSINOPEC Petroleum Exploration and Production Research Institute SINOPEC Exploration and Development Research Institute Southwest Branch CompanySINOPEC

The molecular compositions and stable carbon and hydrogen isotopic compositions of natural gas from the Xinchang gas field in the Sichuan Basin were investigated to determine the genetic types. The natural gas is mainly composed of methane （88.99%-98.01%）, and the dryness coefficient varies between 0.908 and 0.997. The gas generally displays positive alkane carbon and hydrogen isotopic series. The geochemical characteristics and gas-source correlation indicate that the gases stored in the 5th member of the Upper Triassic Xujiahe Formation are coal-type gases which are derived from source rocks in the stratum itself. The gases reservoired in the 4th member of the Xujiahe Formation and Jurassic strata in the Xinchang gas field are also coal-type gases that are derived from source rocks in the 3rd and 4th members of the Xujiahe Formation. The gases reservoired in the 2nd member of the Upper Triassic Xujiahe Formation are mainly coal-type gases with small amounts of oil-type gas that is derived from source rocks in the stratum itself. This is accompanied by a small amount of contribution brought by source rocks in the Upper Triassic Ma＇antang and Xiaotangzi formations. The gases reservoired in the 4th member of the Middle Triassic Leikoupo Formation are oil-type gases and are believed to be derived from the secondary cracking of oil which is most likely to be generated from the Upper Permian source rocks.

关键词： natural gas geochemical characteristics genetic types Xinchang gas field western Sichuan Basin

Gas source of the Middle Jurassic Shaximiao Formation in the Zhongjiang large gas field of Western Sichuan Depression:Constraints from geochemical characteristics of light hydrocarbons

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Energy Geoscience 2024年第2期5卷 141-151页

作者： xiaoqi wu Jun Yang Ping Wang Huaji Li Yingbin Chen Chunhua Ni Huasheng Zeng wuxi Research Institute of Petroleum Geology Petroleum Exploration and Production Research InstituteSINOPECWuxi214126China Key Laboratory of Hydrocarbon Accumulation SINOPECWuxi214126China No.3 Gas Production Plant Southwest Petroleum BranchSINOPECDeyang618000China

The Zhongjiang gas field is a typical large gas field in terrigenous strata of the Western Sichuan *** remains debatable which member of the Upper Triassic Xujiahe Formation served as the source rocks and how significant the member contributed to the gas accumulations in the Zhongjiang gas *** this study,we analyzed the essential characteristics of the Lower Jurassic source rocks and the geochemical features of light hydrocarbons in natural gas from the 2nd(T_(3)χ^(2))and 4th members(T_(3)χ^(4))of the Upper Triassic Xujiahe Formation(T_(3)χ),as well as the Middle Jurassic Shaximiao(J_(2)s)and Qianfoya(J_(2)q)*** on this,we explored the sources of the natural gas in the Zhongjiang gas field and determined the natural gas migration patterns and their effects on the properties of light hydrocarbons in the natural *** results indicate that the Lower Jurassic lacustrine source rocks of the Zhongjiang gas field contain humic organic matter,with vitrinite reflectance(R_(0))values ranging from 0.86%to 0.98%.Samples meeting the criterion for effective source rocks[total organic carbon(TOC)content≥0.75%]exhibited an average TOC content of merely 1.02%,suggesting significantly lower hydrocarbon generation potential than source rocks in the underlying T3x,which show higher thermal maturity and TOC *** natural gas samples from T_(3)χ^(2),T_(3)χ^(4),J_(2)s,and J_(2)q reservoirs,their C_(5-7)iso-alkane content was significantly higher than their n-alkane content,and their methylcyclohexane(MCH)index ranged from 59.0%to 77.3%,indicating the predominance of methylcyclohexane in C_(7)light *** indicated by the origin identification and gas-source correlation based on the geochemical features of light hydrocarbons,the natural gas in the Zhongjiang gas field is typical coal-derived *** gas from the primary pay zone of the Shaximiao Formation,with significantly high K_(1),(P_(2)+N_(2))/C_(7),and P_(3)/C_(7)values,predominantly ori

关键词： Zhongjiang gas field Source rock Origin of natural gas Light hydrocarbon geochemistry Natural gas migration

Learning Effects of the General Subject AI Teacher-Led Courses: A Pilot Study

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Frontiers of Education in China 2023年第4期18卷 377-399页

作者： HUANG Fuquan wu xiaoqi QIU Shiying LIU Yuliang ZENG Wenjie CHEN Siyu The Lab for Neuroscience and Artificial Intelligence in Moral Learning South China Normal UniversityGuangzhou 510631China

The development of artificial intelligence(AI)technologyandthedemand for general-subject teaching give birth to general-subject AI teacher-led *** this study,79 fourth-grade pupils from two classes in a primary school in Guangzhou City are selected as the *** research methods of interview,classroom observation,and questionnaire survey are used to explore the effects of the AI general-subject teacher on pupils’learning effectiveness based on the framework of anthropomorphic learning process *** results show that the AI general-subject teacher can significantly enhance pupils’learning motivation(including intrinsic motivation and extrinsic motivation),increase pupils’learning engagement(including behavioral engagement,cognitive engagement,and emotional engagement),and improve pupils’learning outcomes(including knowledge and skills,process and method,emotional attitude and values).The findings confirm the important role of the AI general-subject teacher as the main instructor to promote pupils’efficient learning and provide a significant reference for solving the shortage problem of excellent teachers and reducing the burden on teachers and reducing the burden on teachers.

关键词： artificial intelligence(AI)teacher general-subject teacher learning motivation learning engagement learning outcomes