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金氏鼻渊方治疗鼻窦炎肺气虚寒证的疗效及对IL-6、IL-8、TNF-α、TGF-β1水平的影响

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四川中医 2024年第5期42卷 162-165页

作者：朱晓朴李敏苏州市中西医结合医院耳鼻咽喉科江苏苏州215101

目的:观察金氏鼻渊方治疗鼻窦炎肺气虚寒证的临床疗效及对鼻分泌物白细胞介素(IL)-6、IL-8、肿瘤坏死因子(TNF)-α、转化生长因子(TGF)-β1水平的影响。方法:选取2021年9月~2023年6月苏州市中西医结合医院耳鼻咽喉科门诊接诊的慢性鼻窦... 详细信息

目的:观察金氏鼻渊方治疗鼻窦炎肺气虚寒证的临床疗效及对鼻分泌物白细胞介素(IL)-6、IL-8、肿瘤坏死因子(TNF)-α、转化生长因子(TGF)-β1水平的影响。方法:选取2021年9月~2023年6月苏州市中西医结合医院耳鼻咽喉科门诊接诊的慢性鼻窦炎病例共计100例,根据随机数字法分为对照组与观察组各50例。对照组患者予常规药物治疗;观察组患者予金氏鼻渊方服用。两组均连续观察1个月。比较两组患者主观病情评分、鼻窦CT评分与鼻内镜检测评分、治疗效果以及鼻分泌物IL-6、IL-8、TNF-α、TGF-β1水平。结果:治疗后,两组病例视觉模拟量表(VAS)、Lund-Mackay、Lund-Kennedy评分显著减少,且观察组减少更显著(P<0.05);1个月疗程后,观察组病例的总有效率为94.00%,显著高于对照组(78.00%)(P<0.05);1个月疗程后,两组患者鼻分泌物IL-6、IL-8、TNF-α、TGF-β1水平明显减少,且观察组减少更显著(P<0.05)。结论:金氏鼻渊方治疗鼻窦炎肺气虚寒证的临床疗效显著,能改善患者的临床症状,抑制炎症反应。

关键词：金氏鼻渊方鼻窦炎肺气虚寒证白细胞介素-6 白细胞介素-8 肿瘤坏死因子-α 转化生长因子β1

数智赋能研究生“导学思政”的内在机理和行动逻辑

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齐鲁师范学院学报 2024年第1期39卷 37-43页

作者：元静张晓普上海工程技术大学材料科学与工程学院上海松江201600 上海工程技术大学化学化工学院上海松江201600

深入推进数智赋能研究生“导学思政”建设是提升研究生思想政治教育的内在要求、遵循研究生人才培养规律的现实需求、落实立德树人根本任务的必然选择。厘清数智化和研究生导学思政两个基本概念的内涵,通过对研究生“导学思政”的教育... 详细信息

深入推进数智赋能研究生“导学思政”建设是提升研究生思想政治教育的内在要求、遵循研究生人才培养规律的现实需求、落实立德树人根本任务的必然选择。厘清数智化和研究生导学思政两个基本概念的内涵,通过对研究生“导学思政”的教育对象、教育内容和教育过程数智化赋能变化的阐释,明确数智化赋能研究生“导学思政”的本质,分析其实践困境,科学提出“核心圈层—关键圈层—辐射圈层”逐级递进的行动逻辑。

关键词：数智化赋能导学思政研究生内在机理行为逻辑

Fast action on short-lived climate pollutants and nature-based solutions to help countries meet carbon neutrality goals

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Advances in Climate Change Research 2022年第4期13卷 564-577页

作者： xiaopu SUN Pu WANG Tad FERRIS Hui LIN Gabrielle DREYFUS Bai-he GU Durwood ZAELKE Yi WANG Institute for Governance&Sustainable Development Washington DC20016USA Institutes of Science and Development Chinese Academy of SciencesBeijing 100190China School of Public Policy and Management University of Chinese Academy of SciencesBeijing 100049China Department of Physics Georgetown UniversityWashington DC20057USA Bren School of Environmental Science&Management University of California Santa BarbaraSanta Barbara CA 93106USA

Scientific studies show that fast actions to reduce near-term warming are essential to slowing self-reinforcing climate feedbacks and avoiding irreversible tipping *** cutting CO_(2) emissions only marginally impacts near-term warming,This study identifies two of the most ffective mitigation strategies to limit near-term warming beyond CO_(2) mitigation,namely reducing short-lived climate pollutants(SLCPs)and promoting targeted nature-based solutions(NbS),and comprehensively reviews the latest scientifie progress in these *** show that quickly reducing SLCP emissions,particularly hydrofuorocarbons(HFCs),methane,and black carbon,from ll relevant sectors can avoid up to 0.6℃ of warming by ***,promoting targeted NbS that protect and enhance natural carbon sinks ncluding in forests,wetlands,grasslands,and agricultural lands,can avoid emssions of 23.8 Gt of CO_(2)e per year in 2030,without jeopardizing food security and *** on the scientific evidence,we provided a series of policy recommendations on SLCPs and NbS,including:1)implementing the Kigali Amendment to reduce HFC emissions;2)deploying cost-effective,sector-based measures to reduce methane and black carbon emissions;and 3)implementing targeted NbS to protect and enhance existing carbon sinks and shifting away from forest-burning *** fast-acting strategies on SLCPs and NbS will play a key role in securing the most avoided warming in the near-term and help countries meet their mid-century carbon neutrality ***,we proposed future research topics,including:improving measurement and monitoring systems and techniques for SLCP emissions;developing and improving assessments of marginal abatement costs for SLCP mitigation in dfferent sectors;better quantifying the avoided warming potential from protecting dfferent types of natural carbon sinks by 2030,2050,and over longer periods;and identifying whether there are any biomass types for energy sources that

关键词： Non-CO_(2)mitigation Short-lived elimate pollutants Climate feedbacks and tipping points Near-term warming Methane Hydrofuorocarbons(HFCs) Black carbon Nature-based solutions(NbS)

Distributed fixed-time attitude coordinated control for multiple spacecraft with actuator saturation

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Chinese Journal of Aeronautics 2022年第4期35卷 292-302页

作者： Han GAO Yuanqing XIA xiaopu ZHANG Guangchen ZHANG School of Automation Beijing Institute of TechnologyBeijing 100081China

This paper investigates the distributed fixed-time attitude coordinated control problem for multiple spacecraft subject to actuator saturation under the directed topology. First, a distributed fixed-time observer is presented for each follower spacecraft to estimate the leader spacecraft’s states. Compared with the commonly used fixed-time observer, the settling time of the proposed fixed-time observer can be easily adjusted by some free design parameters. Next, a distributed fixed-time control scheme is derived by using the estimates of the leader spacecraft’s states and the adding a power integrator technique. When considering actuator saturation, an auxiliary system is utilized to compensate the saturation. Further, a rigorous theoretical proof is provided to show that the practical fixed-time stability of the closed-loop system is ensured. Finally, simulation results illustrate the benefits and effectiveness of the developed control scheme.

关键词： Multiple spacecraft Distributed attitude control Fixed-time observer Fixed-time controller Actuator saturation

基于有限体积法的功能梯度材料流固耦合传热一体化计算

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武汉科技大学学报 2024年第4期47卷 272-281页

作者：龚京风陈金梦宣领宽宫小朴江致远武汉科技大学汽车与交通工程学院湖北武汉430065 上汽通用汽车有限公司武汉分公司湖北武汉430208

为提高功能梯度材料(FGMs)流固耦合传热性能分析的准确性,本文提出了一种二维FGMs流固耦合传热问题一体化计算方法。基于有限体积法离散控制方程,将物性参数和变量储存在单元中心,把耦合面当成特殊的内部面处理,采用中心差分格式处理离... 详细信息

为提高功能梯度材料(FGMs)流固耦合传热性能分析的准确性,本文提出了一种二维FGMs流固耦合传热问题一体化计算方法。基于有限体积法离散控制方程,将物性参数和变量储存在单元中心,把耦合面当成特殊的内部面处理,采用中心差分格式处理离散方程中的面单元参数。通过FGMs圆环热传导算例,讨论了高斯法和最小二乘法两种梯度求解方法对于不同网格的适应性。结果表明,对于非结构化网格,最小二乘法比高斯法具有更好的适应性。对于结构化网格,两种方法都具有良好的适用性。因此,本文采用最小二乘法计算离散方程中的梯度,应用有限体积法求解FGMs方板热传导、自然对流和FGMs流固耦合传热问题。计算结果与文献或商用软件计算结果吻合良好,验证了本文方法的有效性。

关键词：有限体积法流固耦合传热功能梯度材料一体化计算中心差分

Experimental investigation of face instability for tunnels in sandy cobble strata

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Underground Space 2023年第3期10卷 199-216页

作者： Qiguang Di Pengfei Li Mingju Zhang xiaopu Cui Key Laboratory of Urban Security and Disaster Engineering Ministry of EducationBeijing University of TechnologyBeijing 100124China

In order to investigate the influence of face instability for tunnels with different burial depths in sandy cobble strata on earth pressure and the instability region,geomechanical model tests and numerical simulations were *** continuous excavation method was adopted to reduce the pressure of the soil bin and restore the real engineering *** pressure in three directions of the obser-vation section in front of the tunnel face was monitored during the tunneling of the *** of the lateral stress ratios at dif-ferent stages were also *** instability area of the shield tunnel face in sandy cobble strata with different burial depth ratios during the instability stage was obtained based on the change ratio of earth pressure and compared with existing *** earth pressure began to change when the excavation was one shield diameter away from the observation section,and when the excavation reached the observation section,the earth pressure decreased *** burial depth of shield tunnel in the sandy cobble strata has a significant impact on the evolution of soil arch and the size of the failure *** numerical simulation of the continuum medium cannot reflect the stress redistribution characteristics of the granular body like sandy cobble strata,and the failure area or stress distur-bance area obtained by the model test is larger than the numerical simulation *** methods have deviations in analyzing the failure area of shield tunnel face in sandy cobble *** provides not only guidance for shield tunnel excavation engineering in sandy cobble strata,but also a reference for the theoretical research on failure areas.

关键词： Geomechanical model test Sandy cobble strata Face stability Arching effect Shield tunnel

Analytical solutions of limit support pressure and vertical earth pressure on cutting face for tunnels

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Underground Space 2023年第5期12卷 65-78页

作者： Pengfei Li xiaopu Cui Junwei Xia Xinyu Wang Key Laboratory of Urban Security and Disaster Engineering Ministry of EducationBeijing University of TechnologyBeijing 100124China China Railway 19 Bureau Group Rail Traffic Engineering Co.LTD Beijing 101399China School of Civil Engineering Henan Polytechnic UniversityJiaozuo 454000China

This paper focuses on theoretical analytical models to calculate the limit support pressure and vertical earth pressure on the cutting face for *** failure zone is divided into two parts:a sliding failure zone and an upper loosen zone,and the limit support pressure calculation equation is *** verify the rationality of the theoretical model,it was compared with the existing theory,numerical simulation,and centrifugal test,and then the parameter analysis was carried *** results show that the results of this paper agree well with the existing theory,numerical simulation,and centrifugal *** inclination angle of the proposed mechanism is determined based on the results of the existing centrifuge test,and the recommended inclination angle is between 52°+φ/2 and 54°+φ/*** method is proven to be safe and *** can provide a theoretical basis for similar projects.

关键词： Instability and failure Excavation face stability Global method Soil arch effect Limit support pressure

Calibration method of mesoscopic parameter in sandy cobble soil triaxial test based on PFC3D

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Frontiers of Structural and Civil Engineering 2023年第12期17卷 1924-1933页

作者： Pengfei LI xiaopu CUI Yingjie WEI Junwei XIA Xinyu WANG Key Laboratory of Urban Security and Disaster Engineering of Ministry of Education Beijing University of TechnologyBeijing 100124China China Railway 14th Bureau Group Co. Ltd.Jinan 250014China China Railway 19 Bureau Group Rail Traffic Engineering Co. Ltd.Beijing 101399China School of Civil Engineering Henan Polytechnic UniversityJiaozuo 454000China

This paper presents a rapid and effective calibration method of mesoscopic parameters of a threedimensional particle flow code(PFC3D)model for sandy cobble *** method is based on a series of numerical tests and takes into account the significant influence of mesoscopic parameters on macroscopic ***,numerical simulations are conducted,with five implementation ***,the multi-factor analysis of variance method is used to analyze the experimental results,the mesoscopic parameters with significant influence on the macroscopic response are singled out,and their linear relations to macroscopic responses are estimated by multiple linear ***,the parameter calibration problem is transformed into a multi-objective function optimization *** simulation results are in good agreement with laboratory results both qualitatively and *** results of this study can provide a basis for the calibration of microscopic parameters for the investigation of sandy cobble soil mechanical behavior.

关键词： sandy cobble soil particle flow code orthogonal experiment regression analysis multi-objective optimization calibration

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应急广播传输覆盖类行业标准解读

广播与电视技术 2024年第2期51卷 16-22页

作者：刘春江马艳马小朴国家广播电视总局广播电视科学研究院北京100866 国家广播电视总局广播电视规划院北京100045

本文主要从术语定义、应急广播消息封装协议、应急广播前端和终端处理要求等方面对《有线数字电视应急广播系统技术规范》《模拟调频广播应急广播技术规范》等应急广播传输覆盖类行业标准的修订情况进行了说明。

关键词：应急广播传输覆盖技术标准