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Effects of substituting Ni with M (M=Cu, Al and Mn) on microstructures and electrochemical characteristics of La-Mg-Ni system (PuNi_3-type) electrode alloys

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Rare Metals 2006年第z1期25卷 25-32页

作者： ZHANG Yanghuan ZHAO Dongliang DONG xiaoping REN Huiping guo Shihai WANG Xinlin Department of Functional Material Research Central Iron and Steel Research Institute Beijing 100081 China School of Material Inner Mongolia University of Science and Technology Baotou 014010 China Department of Functional Material Research Central Iron and Steel Research Institute Beijing 100081 China Department of Functional Material Research Central Iron and Steel Research Institute Beijing 100081 China School of Material University of Science and Technology Beijing Beijing 100083 China School of Material Inner Mongolia University of Science and Technology Baotou 014010 China Department of Functional Material Research Central Iron and Steel Research Institute Beijing 100081 China Department of Functional Material Research Central Iron and Steel Research Institute Beijing 100081 China

In order to improve the electrochemical cycle stability of La-Mg-Ni system (PuNi3-type) hydrogen storage alloy, Ni in the alloys was partially substituted by M (M=Cu, Al, Mn). A new La-Mg-Ni system electrode alloys La0.7Mg0.3Ni2.55-xCo0.45Mx (M=Cu, Al, Mn; x=0, 0.1) were prepared by casting and rapid quenching. The effects of element substitution and rapid quenching on the microstructures and electrochemical performances of the alloys were investigated. The results by XRD, SEM and TEM show that the alloys have a multiphase structure, including the (La, Mg)Ni3 phase, the LaNi5 phase and the LaNi2 phase. The rapid quenching and element substitution have an imperceptible influence on the phase compositions of the alloys, but both change the phase abundance of the alloys. The rapid quenching significantly improves the composition homogeneity of the alloys and markedly decreases the grain size of the alloys. The Cu substitution promotes the formation of an amorphous phase in the as-quenched alloy, and a reversal result by the Al substitution. The electrochemical measurement indicates that the element substitution decreases the discharge capacity of the alloys, whereas it obviously improves the cycle stability of the alloys. The positive influence of element substitution on the cycle life of the alloys is in sequence Al>Cu>Mn, and negative influence on the discharge capacity is in sequence Al>Mn>Cu. The rapid quenching significantly enhances the cycle stability of the alloys, but it leads to a different extent decrease of the discharge capacity of the alloys.

关键词： element substitution rapid quenching La-Mg-Ni system electrode alloy microstructures electrochemical performances

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Deciphering the regulatory code of histone modifications in plants

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Journal of Genetics and Genomics 2022年第11期49卷 1064-1067页

作者： Zhaohong Li Dongwei Li Ye Li xiaoping guo Ruolin Yang State Key Laboratory of Crop Stress Biology for Arid Areas College of Life SciencesInstitute of Future AgricultureNorthwest Agriculture&Forestry UniversityYanglingShaanxi 712100China

Eukaryotic genomes are compacted into histone-wrapped chromatin,which provides an opportunity to fine-tune the gene expression by dynamically impeding or reinforcing the accessibility of the genome to the transcription factors(TFs)and *** modification of histones is one of the various mechanisms to regulate DNA exposure by altering the physical properties of nucleosomes(Klemm et al.,2019).In plants,histone modifications play a critical role in establishing the cell identity and responding to environmental cues,including responses to temperature,alterations of flowering time(Liu et al.,2010;He et al.,2021).

关键词： cues establishing nucleosome

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Seed-specific overexpression of cotton GhDGAT1 gene leads to increased oil accumulation in cottonseed

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The Crop Journal 2021年第2期9卷 487-490页

作者： Peng Wu Xiaolan Xu Jingwen Li Jun Zhang Siyuan Chang Xiyan Yang xiaoping guo National Key Laboratory of Crop Genetic Improvement Huazhong Agricultural UniversityWuhan 430070HubeiChina

As the main byproduct of cotton fiber,the cotton seed yields about 1.6 times that of fiber,with its oil rich in unsaturated fatty acids,mainly linoleic *** is desirable for breeders to increase the oil content of cottonseed without affecting the yield and quality of cotton *** this study,a seed-specific promoter-(alpha-globulin gene promoter-)driven GhDGAT1 overexpression vector(P_(aGlob)-GhDGAT1)was constructed and used to transform an upland cotton line YZ1(Gossypium hirsutum).Overexpression of the cotton gene GhDGAT1 in cotton seeds increased its total oil content from 4.7%to 13.9%in different transgenic lines and different *** the increase of oil content,the composition and contents of the main fatty acids in cotton seed also changed,as reflected by the contents of the main saturated fatty acids and unsaturated oleic ***1 could be used to increase oil content and improve oil composition in cottonseed.

关键词： aGP promoter Cotton Fatty acid GhDGAT1 Seed oil

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Duration of humoral immunity from smallpox vaccination and its cross-reaction with Mpox virus

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Signal Transduction and Targeted Therapy 2023年第10期8卷 4942-4948页

作者： Entao Li xiaoping guo Dongxiang Hong Qizan Gong Wenyu Xie Tingting Li Jian Wang Xia Chuai Sandra Chiu Department of Laboratory Medicine The First Affiliated Hospital of USTCDivision of Life Sciences and MedicineUniversity of Science and Technology of ChinaHefeiAnhui China Division of Life Sciences and Medicine University of Science and Technology of ChinaHefeiAnhuiChina Department of Clinical Laboratory First Affiliated Hospital of Anhui Medical UniversityHefeiAnhuiChina State Key Laboratory of Virology Wuhan Institute of VirologyCenter for Biosafety Mega ScienceChinese Academy of SciencesWuhanHubeiChina Core Unit of National Clinical Research Center for Laboratory Medicine HefeiAnhuiChina Key Laboratory of Anhui Province for Emerging and Reemerging Infectious Diseases HefeiAnhuiChina

The ongoing pandemic caused by mpox virus(MPxV)has become an international public health emergency that poses a significant threat to global *** vaccinia virus Tiantan strain(VTT)was used to vaccinate against smallpox in China 42 years *** is urgent to assess the level of immunity to smallpox in individuals vaccinated 43 or more years ago and evaluate their immunological susceptibility to MPxV.

关键词： immunity vaccination susceptibility

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KLF4 expression is associated with differentiation stages of leukemia cells in both cell lines and patients

KLF4 expression is associated with differentiation stages of...

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2012年江浙沪儿科学术年会暨浙江省医学会儿科学分会学术年会、儿内科疾病诊治新进展国家级学习班

作者： xiaoping guo Yongmin Tang Division of Hematology-oncology Children's Hospital of Zhejiang University School of Medicine

Background and Objectives Biomarkers on malignant cells may predict prognostic significance. Krüppel-like factor 4 (KLF4) has been reported to be expressed variably on leukemia cells, but its expression patterns in leukemias with different differentiation stages and its prognostic significance remain to be elucidated. The aim of this study was to examine the KLF4 expression in human leukemias and its clinical significance. Materials and Methods RT-PCR and real-time PCR were used to detect KLF4 expression in 9 leukemia cell lines and 101 leukemia patients. MRD was detected with flow cytometry in 39 bone marrows at the time of remission induction. Results KLF4 mRNA expressed in 5/16 (31.25%) AML and 11/28 (39.29%) ALLcases, significantly lower than that in control (9/11 (81.82%), p<0.05). Lower expressions of KLF4 in AML-M1 vs other subtypes of AML (p<0.05), C-ALL vs Pre-B ALL (p=0.045), Pro-T ALL vs T-ALL (p<0.05) were found, indicating the significant association with the differentiation stages of leukemias. Observation using leukemia cell lines showed the similar ***4 expression levels were inversely related to the MRD levels, particularly in patients with AML (r = -0.52, p = 0.024). Conclusions KLF4 expression level is associated with differentiation stages of leukemias and with low levels of MRD in AML, which may predict a better outcome.

关键词： AML MRD KLF4 expression is associated with differentiation stages of leukemia cells in both cell lines and patients

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基于测地线距离统计量的多工况间歇过程监测

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化工学报 2015年第1期66卷 291-298页

作者：郭小萍李婷李元沈阳化工大学信息工程学院辽宁沈阳110142

针对间歇过程数据具有非线性和多工况的特点,提出一种基于测地线距离统计量(geodesic distance statistic,GDS)的监测方法。首先,对多工况间歇过程数据按批次方向展开及标准化,利用主元分析(principal component analysis,PCA)方法进行... 详细信息

针对间歇过程数据具有非线性和多工况的特点,提出一种基于测地线距离统计量(geodesic distance statistic,GDS)的监测方法。首先,对多工况间歇过程数据按批次方向展开及标准化,利用主元分析(principal component analysis,PCA)方法进行降维;然后,在降维空间获得赋权邻接矩阵,提出采用改进的Dijkstra(improved Dijkstra,IDijkstra)算法使Dijkstra算法更易于实现,计算各批次之间的测地线距离,用以表征非线性多工况数据之间的实际最短距离,更好地体现批次数据之间的局部近邻关系。通过构造测地线距离α次方统计量Dα进行过程监测,与欧氏距离平方和D2相比将减小边缘训练数据距离的偏离程度。最后,通过在数值仿真和工业仿真实例中的应用,验证所提算法的有效性。

关键词：多工况非线性间歇过程测地线距离算法

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基于鲁棒测地线距离的复杂间歇过程故障检测

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仪器仪表学报 2014年第12期35卷 2681-2689页

作者：郭小萍李婷李元沈阳化工大学信息工程学院沈阳110142

针对多工况间歇过程受噪声等影响使数据呈现出离群点、非线性等特征,本文提出一种基于鲁棒测地线距离(RGD)的故障检测方法。首先利用局部离群概率(LOP)剔除离群点之后标准化,减轻噪声干扰,提高故障检测的鲁棒性;接着,采用多向主元分析(M... 详细信息

针对多工况间歇过程受噪声等影响使数据呈现出离群点、非线性等特征,本文提出一种基于鲁棒测地线距离(RGD)的故障检测方法。首先利用局部离群概率(LOP)剔除离群点之后标准化,减轻噪声干扰,提高故障检测的鲁棒性;接着,采用多向主元分析(MPCA)进行特征提取,获得主元;然后,在主元空间求得赋权邻接矩阵,通过改进的迪科斯彻(IDijkstra)算法计算各批次间的测地线距离,表征数据间的实际最短距离,从而更好地体现批次数据间的局部近邻关系。最后,通过构造测地线距离α次方统计量Lo D进行过程故障检测,与欧氏距离平方和统计量相比可提高样本的有效性,减小边缘训练数据距离的偏离程度。在人工三臂螺旋数值仿真和半导体工业实例中进行应用,结果表明了所提算法的有效性。

关键词：多工况间歇过程监视局部离群概率测地线距离改进迪科斯彻算法

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基于改进重构贡献图的故障定位方法

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仪器仪表学报 2015年第5期36卷 1193-1200页

作者：郭小萍杨猛李元沈阳化工大学信息工程学院沈阳110142

针对重构贡献(RBC)方法仅适合单变量故障的定位及贡献图中出现拖尾效应(SE)的问题,本文提出一种基于改进重构贡献图(MRBCP)的故障定位方法。采用概率主元分析(PPCA)建立监视模型和统一量度的监视统计量,克服PCA方法中不同量度的监视统... 详细信息

针对重构贡献(RBC)方法仅适合单变量故障的定位及贡献图中出现拖尾效应(SE)的问题,本文提出一种基于改进重构贡献图(MRBCP)的故障定位方法。采用概率主元分析(PPCA)建立监视模型和统一量度的监视统计量,克服PCA方法中不同量度的监视统计量造成的诊断结果不一致的缺点。对于故障样本,以变量的重构监视统计量为贡献统计量,通过组合最大化思想对故障变量进行逐次定位。在历史故障信息未知的情况下,能够进行多变量故障的定位,然后在定位出的故障变量中进行贡献图分析,进一步对故障变量实现准确定位,从而避免了拖尾效应。通过数值案例和TE过程——实际化工过程的真实模拟过程进行实验,并与基本RBC方法、基于PCA的MRBCP方法进行比较,结果表明了所提方法的有效性。

关键词：故障定位概率主元分析拖尾效应改进重构贡献图

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Cytochrome P450 mono-oxygenase CYP703A2 plays a central role in sporopollenin formation and ms5ms6 fertility in cotton

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Journal of Integrative Plant Biology 2022年第10期64卷 2009-2025页

作者： Huanhuan Ma Yuanlong Wu Ruiling Lv Huabin Chi Yunlong Zhao Yanlong Li Hongbo Liu Yizan Ma Longfu Zhu xiaoping guo Jie Kong Jianyong Wu Chaozhu Xing Xianlong Zhang Ling Min National Key Laboratory of Crop Genetic Improvement Huazhong Agricultural UniversityWuhan 430070China College of Biology and Agricultural Resources Huanggang Normal UniversityHuanggang 438000China College of Plant Science and Technology Huazhong Agricultural UniversityWuhan 430070China Institute of Economic Crops Xinjiang Academy of Agricultural SciencesXinjiang 830091China State Key Laboratory of Cotton Biology Institute of Cotton Research of Chinese Academy of Agricultural SciencesAnyang 455000China

The double-recessive genic male-sterile(ms)line ms5 ms6 has been used to develop cotton(Gossypium hirsutum)hybrids for many years,but its molecular-genetic basis has remained ***,we identified the Ms5 and Ms6 loci through map-based cloning and confirmed their function in male sterility through CRISPR/Cas9 gene ***5 and Ms6 are highly expressed in stages 7–9 anthers and encode the cytochrome P450 mono-oxygenases CYP703A2-A and *** ms5 mutant carries a single-nucleotide C-to-T nonsense mutation leading to premature chain termination at amino acid 312(GhCYP703A2-A^(312aa)),and ms6 carries three nonsynonymous substitutions(D98E,E168K,and G198R)and a synonymous mutation(L11L).Enzyme assays showed that GhCYP703A2 proteins hydroxylate fatty acids,and the ms5(GhCYP703A2-A^(312aa))and ms6(GhCYP703A2-D^(D98E,E168K,G198R))mutant proteins have decreased enzyme *** and lipidomic analyses showed that in ms5 ms6 plants,C12–C18 free fatty acid and phospholipid levels are significantly elevated in stages 7–9 anthers,while stages 8–10 anthers lack sporopollenin fluorescence around the pollen,causing microspore degradation and male ***,our characterization uncovered functions of GhCYP703A2 in sporopollenin formation and fertility,providing guidance for creating male-sterile lines to facilitate hybrid cotton production and therefore exploit heterosis for improvement of cotton.

关键词： cotton cytochrome P450 mono-oxygenase doublerecessive genic male sterility sporopollenin formation

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危机传播中的新闻发言人制度

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中国广播电视学刊 2006年第3期 28-29,27页

作者：郭小平武汉大学新闻与传播学院

新闻发言人，即“国家、政党、社会团体任命或指定的专职（比较小的部门为兼职）新闻发布人员，其职位一般是该部门中层以上的负责人。新闻发言人的职责是在一定时间内就某一重大事件或时局的问题．举行新闻发布会．或约见个别记者．发... 详细信息

新闻发言人，即“国家、政党、社会团体任命或指定的专职（比较小的部门为兼职）新闻发布人员，其职位一般是该部门中层以上的负责人。新闻发言人的职责是在一定时间内就某一重大事件或时局的问题．举行新闻发布会．或约见个别记者．发布有关新闻或阐述本部门的观点立场，并代表有关部门回答记者的提问。”

关键词：新闻发言人制度危机传播新闻发布会社会团体重大事件部门负责人记者

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