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Progress in Electrospun Fibers for Manipulating Cell Behaviors

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Advanced Fiber Materials 2023年第4期5卷 1241-1272页

作者： Yingnan Liu Qingxia Guo xiaopei zhang Yuanfei Wang Xiumei Mo Tong Wu Institute of Neuroregeneration and Neurorehabilitation Qingdao Medical CollegeQingdao UniversityQingdao 266071ShandongChina State Key Laboratory for Modification of Chemical Fibers and Polymer Materials Donghua UniversityShanghai 201620China Central Laboratory Qingdao Stomatological Hospital Affiliated to Qingdao UniversityQingdao 266001ShandongChina College of Chemistry Chemical Engineering and BiotechnologyDonghua UniversityShanghai 201620China Shandong Key Laboratory of Medical and Health Textile Materials Collaborative Innovation Center for Eco‑textiles of Shandong Province and the Ministry of EducationCollege of Textiles&ClothingQingdao 266071ShandongChina

The manipulation of cell behaviors is essential to maintaining cell functions,which plays a critical role in repairing and regenerating damaged *** this end,a rich variety of tissue-engineered scaffolds have been designed and fabricated to serve as matrix for supporting cell growth and *** others,scaffolds made of electrospun fibers showed great potential in regulating cell behaviors,mainly owing to their capability of replicating the dimension,composition,and function of the natural extracellular *** particular,electrospun fibers provided both topological cues and biofunctions simply by adjusting the electrospinning parameters and/or *** this review,we summarized the most recent applications and advances in electrospun nanofibers for manipulating cell ***,the engineering of the secondary structures of individual fibers and the construction of two-dimensional nanofiber mats and nanofiber-based,three-dimensional scaffolds were ***,the functionalization strategies,such as endowing the fibers with bioactive,physical,and chemical cues,were ***,the typical applications of electrospun fibers in controlling cell behaviors(i.e.,cell adhesion and proliferation,infiltration,migration,neurite outgrowth,stem cell differentiation,and cancer cell capture and killing)were *** together,this review will provide valuable information to the specific design of nanofiber-based scaffolds and extend their use in controlling cell behaviors for the purpose of tissue repair and regeneration.

关键词： Electrospun nanofibers Structures Functionalization Cell behaviors Tissue repair and regeneration

多模式教学提高神经重症专业中西医临床教学质量的探讨

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中国卫生产业 2024年第5期21卷 235-237页

作者：卢鸿基张小培李惠平王立新广州中医药大学第二附属医院神经重症科广东广州510120

神经重症是近十多年来逐步发展起来的重症医学亚专科,具有专业性强、多学科融合、有创操作多等特点,对于神经重症医学专业的研究生来说,学习难度大,使用传统的教学模式进行教学,难以满足现代化教学需求。本文探讨运用清单式教学模式、... 详细信息

神经重症是近十多年来逐步发展起来的重症医学亚专科,具有专业性强、多学科融合、有创操作多等特点,对于神经重症医学专业的研究生来说,学习难度大,使用传统的教学模式进行教学,难以满足现代化教学需求。本文探讨运用清单式教学模式、“文献复习课”教学法、以问题为基础的学习(Problem-based Learning,PBL)教学法、多媒体和模拟操作等方法,提升神经重症中西医临床教学质量。

关键词：神经重症多模式教学教学质量

神经重症患者留置双腔胃肠营养管护理专家共识

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护理学杂志 2024年第18期39卷 48-52+81页

作者：张晓梅袁超罗彦嗣李慧娟杜敏张小培李淑恩项丽君崔艳丽南方医科大学南方医院神经内科中山大学附属第三医院护理部广州市中西医结合医院护理部广东省中医院神经重症科东莞市人民医院普济院区神经内科ICU

目的形成神经重症患者留置双腔胃肠营养管护理专家共识，推动护士规范、安全、有效地实施双腔胃肠营养管喂养，满足患者营养需求。方法检索、评价和汇总神经重症患者胃肠营养管护理的相关证据，提取相关的推荐意见，形成专家共识初稿... 详细信息

目的形成神经重症患者留置双腔胃肠营养管护理专家共识，推动护士规范、安全、有效地实施双腔胃肠营养管喂养，满足患者营养需求。方法检索、评价和汇总神经重症患者胃肠营养管护理的相关证据，提取相关的推荐意见，形成专家共识初稿，通过1轮专家函询和2轮专家论证会，结合专家意见修改、完善各条目内容，形成专家共识终稿。结果最终形成的专家共识包括神经重症患者双腔胃肠营养管喂养的操作性定义、置管适应证、置管禁忌证、置管及维护、拔管指征5个方面。结论形成的专家共识实用性较强，可为神经重症患者双腔胃肠营养管的临床护理实践和质量控制提供指导依据。

关键词：神经重症肠内营养双腔胃肠营养管胃管肠管管饲喂养胃肠减压专家共识

Recent advances in functional fiber electronics

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SusMat 2021年第1期1卷 105-126页

作者： xiaopei zhang Huijuan Lin Huan Shang Jingsan Xu Jixin Zhu Wei Huang Key Laboratory of Flexible Electronics and Institute of Advanced Materials Jiangsu National Synergetic Innovation Center for Advanced MaterialsNanjing Tech UniversityNanjingP.R.China School of Chemistry Physics and Mechanical EngineeringQueensland University of TechnologyBrisbaneQueenslandAustralia Frontiers Science Center for Flexible Electronics Xi’an Institute of Flexible Electronics(IFE)and Xi’an Institute of Biomedical Materials&EngineeringNorthwestern Polytechnical University(NPU)Xi’anP.R.China

Rapid development ofwearable electronicswith various functionalities has stimulated the demand to construct functional fiber devices due to their merits of mechanical flexibility,weavability,miniaturization,and *** this end,fiber components which can realize the functions of energy storage and conversion,actuating plus sensing have gained increasing ***,we summarize the recent progress with respect to fiber material preparation,innovative structure design,and device performance in this review,also highlighting the possibility of integrated fiber electronics as an extension of application,the remaining challenges and future perspectives toward next-generation smart systems and to facilitate their commercialization.

关键词： actuator energy storage device fiber material integration system strain detection

Promotion of Neurite Outgrowth and Extension Using Injectable Welded Nanofibers

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Chemical Research in Chinese Universities 2021年第3期37卷 522-527页

作者： FENG Zhendong zhang xiaopei LIU Na WANG Yue ZHOU Ziyi GLEBOV O.Oleg WU Tong Institute of Neuroregeneration and Neurorehabilitation Qingdao UniversityQingdao266071P.R.China Qingdao Medical College Qingdao UniversityQingdao266071P.R.China Department of Old Age Psychiatry The Institute of PsychiatryPsychology&NeuroscienceKing’s College LondonDe Crespigny ParkDenmark HillLondonSE58AFUK

We report a general strategy to develop injectable welded nanofibers to facilitate the outgrowth and extension of *** this case,nonwoven mats of uniaxially aligned poly(caprolactone)(PCL)nanofibers were firstly cut into several small pieces with fixed fiber lengths of 25,50 and 100µm,respectively,using a cryotome.A tissuelyser was employed to homogenize and disperse the short nanofibers to a homogeneous *** tuning treatment duration from 100 s to 400 s,the temperature of the suspension was brought close to the melting point of *** such,the short nanofibers were welded at their cross points while the fibers far away from the cross points remain the original *** showed that the viability of neuroblastoma SH-SY5Y cells and their neurite outgrowth and extension were enhanced with the use of such welded short *** together,this study provides a simple way to generate injectable welded nanofibers,holding potential in affecting neurite outgrowth and extension for nerve repair,in particular,in the central nervous system.

关键词： Electrospinning Nanofiber Welding Injectable Neurite outgrowth

Experimental observation of topologically protected defect states in silicon waveguide arrays

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Chinese Optics Letters 2020年第5期18卷 16-20页

作者： Tianying Lin Ze Chen xiaopei zhang He Li Xiaoping Liu Haibin Lu National Laboratory of Solid State Microstructures and College of Engineering and Applied Sciences Nanjing UniversityNanjing 210093China Collaborative Innovation Center of Advanced Microstructures Nanjing UniversityNanjing 210093China

Photonic waveguide arrays provide a simple and versatile platform for simulating conventional topological ***,we investigate a novel one-dimensional(1D)topological band structure,a dimer chain,consisting of silicon waveguides with alternating self-coupling and *** mode theory is used to study topological features of such a *** is found that topological invariants of our proposed model are described by the global Berry phase instead of the Berry phase of the upper or lower energy band,which is commonly used in the1 D topological models such as the Su–Schrieffer–Heeger ***,we design an array configuration composed of two dimer patterns with different global Berry phases to realize the topologically protected *** topologically protected propagation feature is simulated based on the finite-difference time-domain method and then observed in the *** results provide an in-depth understanding of the dynamics of the topological defect state in a 1D silicon waveguide array,and may provide different routes for on-chip lightwave shaping and routing.

关键词： fiber optics fiber optics communications fiber optics imaging

Ore-controlling Regularitiesof Structureinthe Lehong Lead-zinc Deposit, Northeastern Yunnan

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Acta Geologica Sinica(English Edition) 2017年第S1期91卷 197-198页

作者： CUI Junhao HAN Runsheng ZHAO Dong zhang xiaopei Faculty of Land Resources Engineering University of Science and TechnologyKunming Southwest Institute of Geological Survey Geological Survey Center for Non-ferrous Metals Resources

1 Introduction The Lehonglead-zincdeposit is a large-sized Pb-Zn depositnewly found in recent years in the Sichuan-Yunnan-Guizhou Lead-zinc Poly-metallic Mineralization Area,which occurrenceis strictly

关键词： REE Pb Zn Northeastern Yunnan Ore-controlling Regularitiesof Structureinthe Lehong Lead-zinc Deposit

The seismic CT method in measuring rock bodies

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Applied Geophysics 2006年第3期3卷 192-195页

作者： Du Lizhi zhang xiaopei Niu Jianjun Wang Xuege Feng Guolei College of Construction Engineering Jilin University Changchun 130026 China College of Resource and Environment Jilin University Changchun 130026 China

The seismic computed tomography （CT） method is derived from the basic principles of X-ray section scanning first applied in medical science. The method records P-wave arrivals between shots and receivers in separate boreholes. Using the velocity information from 2D seismic P-wave arrival inversion, we can determine the distribution of velocity in rock and soil bodies. This paper introduces a practical case of using the seismic CT method for detecting the structure of the rocks for tunnel engineering and to utilize SIRT algorithms for doing first arrival time iterative inversion. Compared with other exploration methods, it is more efficient and accurate.

关键词： seismic computed tomography P-wave velocity travel time inversion.

Quantitative Analysis of Mineralization-Alteration Index about the Huize Lead-zinc district in Northeast Yunnan, China

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Acta Geologica Sinica(English Edition) 2017年第S1期91卷 249-250页

作者： zhang xiaopei HAN Runsheng ZHAO Dong QIU Wenlong HE Jiaojiao CUI Junhao Faculty of Land Resource Engineering Kunming University of Science and Technology South-West Institute of Geological Survey Geological Survey Center for Nonferrous Metals Resources

1 Introduction The super-large Huize lead-zinc ore district is one of the most representative lead-zinc deposits in Northeastern Yunnan poly-metallic deposit concentration *** far,studies(Liu and Lin,1999;Han et al.,2007)on the type of deposits like the Huize lead-zinc deposit,focused on deposit genesis,the sources of metallogenic materials,

关键词： Pb Zn China Quantitative Analysis of Mineralization-Alteration Index about the Huize Lead-zinc district in Northeast Yunnan