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Electroacupuncture with different waveforms for primary dysmenorrhea:A randomized controlled trial

Journal of Traditional Chinese Medical Sciences 2024年第3期11卷 357-362页

作者： xiaona wu Jingxue Yuan Jinxia Ni Xiuli Ma Ziniu Zhang Yini Hua Juwei Dong Bob Peng Wang Dongzhimen Hospital Beijing University of Chinese MedicineBeijing 100700China New Zealand College of Chinese Medicine Auckland 17467New Zealand

Objective To observe and compare the clinical effects of different electroacupuncture waveforms on primary *** This was a prospective,randomized,three-group,parallel-controlled *** with primary dysmenorrhea were randomly divided into dense-sparse wave,continuous wave,and discontinuous wave groups in a 1:1:1 *** lateral Ciliao(BL 32)points were *** three groups started treatment 3–5 days before menstruation,once a day for six sessions per course of treatment,one course of treatment per menstrual cycle,and three menstrual *** primary outcome measure was the proportion with an average visual analog scale(VAS)score reduction of≥50%from baseline for dysmenorrhea in the third menstrual cycle during *** secondary outcome measures included changes in dysmenorrhea VAS scores,Cox Menstrual Symptom Scale scores and the proportion of patients taking analgesic *** The proportion of cases where the average VAS score for dysmenorrhea decreased by≥50%from baseline in the third menstrual cycle was not statistically significant(P>.05).Precisely 30 min after acupuncture and regarding immediate analgesia on the most severe day of dysmenorrhea,there was a statistically significant difference in the dense-sparse wave group compared with the other two groups during the third menstrual cycle(P<.05).Additionally,there was a statistically significant difference between the dense-sparse wave and discontinuous wave groups 24 h after acupuncture(P<.05).Conclusions Waveform electroacupuncture can alleviate primary dysmenorrhea and its related symptoms in *** three groups showed similar results in terms of short-and long-term analgesic efficacy and a reduction in the number of patients taking analgesic *** achieving immediate analgesia,the dense-sparse wave group was slightly better than the other two groups.

关键词： Waveforms Ciliao(BL 32) Electroacupuncture Primary dysmenorrhea Randomized controlled trial Dense-sparse waves Continuous waves Discontinuous waves

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MXene基复合水凝胶在修复感染创面中的研究进展

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复合材料学报 2024年第7期41卷 3427-3441页

作者：吴晓娜汪宜宇赵凯黑龙江大学生命科学学院农业微生物技术教育部工程研究中心黑龙江省寒区植物基因与生物发酵重点实验室哈尔滨150080 台州学院生命科学学院浙江省植物进化生态学与保护重点实验室台州市生物医药与高端剂型重点实验室台州318000

感染创面严重危害着人类的生活质量甚至是生命健康,因此研发高效且副作用小的抗菌生物材料用于修复感染创面具有广阔的市场前景。二维过渡金属碳化物(MXene)是一种新型的二维片状材料,具有优异的抗菌性能,其抗菌机制主要包括物理捕获理... 详细信息

感染创面严重危害着人类的生活质量甚至是生命健康,因此研发高效且副作用小的抗菌生物材料用于修复感染创面具有广阔的市场前景。二维过渡金属碳化物(MXene)是一种新型的二维片状材料,具有优异的抗菌性能,其抗菌机制主要包括物理捕获理论、红外热效应、活性氧(ROS)生成理论、胞间分子泄露理论等,因此MXene有望成为一种更安全、有效、广谱的抗菌手段。通过水凝胶包裹MXene制成的MXene复合水凝胶比单纯水凝胶具有更佳的抗菌、抗氧化性以及光热效应等优势。本文综述了MXene的抗菌机制,并就近年来报道的MXene复合水凝胶修复感染创面的研究进行全面综述和总结。

关键词： MXene 复合水凝胶抗菌创面修复应用

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乡村振兴视角下红色文旅产业融合发展研究

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山东农业工程学院学报 2024年第7期41卷 54-58页

作者：吴小娜河南警察学院河南郑州450046

红色文旅是乡村旅游的重要形式,能够振兴乡村的产业、生态环境、文化以及人才。党的十九届五中全会再次强调,将发展红色旅游和乡村旅游作为文化建设的重要内容。红色文化和乡村旅游具有共生效应,能够在相互促进的作用机制中激发经济潜... 详细信息

红色文旅是乡村旅游的重要形式,能够振兴乡村的产业、生态环境、文化以及人才。党的十九届五中全会再次强调,将发展红色旅游和乡村旅游作为文化建设的重要内容。红色文化和乡村旅游具有共生效应,能够在相互促进的作用机制中激发经济潜力、促进乡村发展。探索红色精神、红色遗迹与乡村旅游项目的融合发展路径成为推进这一工作的关键,研究过程从打造红色文旅品牌、多元产业汇聚、红色景区规划设计、旅游资源整合等方面提出了具体的融合发展策略。

关键词：乡村振兴红色文旅产业融合发展路径

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电动自行车综合治理对策研究——以深圳市为例

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交通与运输 2024年第S1期40卷 190-193页

作者：田浩洋吴小娜李锦彬深圳市城市交通规划设计研究中心股份有限公司深圳518000

随着电动自行车保有量激增,深圳城市交通管理面临一系列新的挑战。为构建安全有序的电动自行车出行环境,本研究基于数据调查,分析深圳市电动自行车的发展现状与问题,针对非机动车道不足、配建标准低、停车充电设施不完善、信息化手段不... 详细信息

随着电动自行车保有量激增,深圳城市交通管理面临一系列新的挑战。为构建安全有序的电动自行车出行环境,本研究基于数据调查,分析深圳市电动自行车的发展现状与问题,针对非机动车道不足、配建标准低、停车充电设施不完善、信息化手段不足、监管闭环难等问题,提出设施供给优化和治理能力提升的对策。

关键词：电动自行车综合治理交通秩序交通安全对策

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人工智能视觉识别系统在外来医疗器械检查中的应用效果

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护士进修杂志 2024年第2期39卷 161-163,203页

作者：吴小娜陈慧何倩刘佳微四川大学华西医院/华西护理学院洗浆消毒供应中心四川成都610041

目的探讨人工智能视觉识别系统在消毒供应中心(CSSD)外来骨科医疗器械包装质量的应用效果。方法我院于2022年1月将采集在CSSD处置的骨科外来器械信息,包括(图像、名称规格、数量)等传送至人工智能视觉识别系统中存档,实现图像数据分... 详细信息

目的探讨人工智能视觉识别系统在消毒供应中心(CSSD)外来骨科医疗器械包装质量的应用效果。方法我院于2022年1月将采集在CSSD处置的骨科外来器械信息,包括(图像、名称规格、数量)等传送至人工智能视觉识别系统中存档,实现图像数据分析与回溯、归档预警提示。即选取2021年2-12月系统应用前我院消毒供应中心接收处理的9 600包骨科外来器械为对照组。2022年1月-11月系统应用后的9 600包为观察组,比较2组医疗器械包装质量及管理工作情况(包装质量、平均耗时、使用满意度)。结果观察组医疗器械包装质量优于对照组,差异有统计学意义(P<0.05);包装平均耗时及使用满意度优于对照组,差异有统计学意义(P<0.05)。结论人工智能视觉识别系统在CSSD外来骨科医疗器械包装环节,核查应用中效果较好。提升包装质量的同时,也优化了外来骨科医疗器械管理流程、提高了手术室满意度和工作效率。

关键词：消毒供应中心人工智能视觉识别外来骨科医疗器械包装质量

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Effect of potassium permanganate dosing position on the performance of coagulation/ultrafiltration combined process

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Chinese Journal of Chemical Engineering 2018年第1期26卷 89-95页

作者： He Zhao Liang Wang Hongwei Zhang xiaona wu Bin Zhao Fei Han School of Environmental Science and Technology Tianjin UniversityTianjin 300072China State Key Laboratory of Separation Membranes and Membrane Processes Tianjin Polytechnic UniversityTianjin 300387China School of Civil Engineering and Transportation Hebei University of TechnologyTianjin 300401China

The effects of potassium permanganate(KMnO_4)dosing position on the natural organic matter(NOM)removal as well as membrane fouling were investigated in the coagulation/ultrafiltration combined ***_4 oxidation altered the NOM characteristics in terms of hydrophobicity and molecular weight,and destroyed humic substances originated from terraneous organisms in raw *** optimal KMnO_4 dosage was 0.5 mg·L^(-1) in the peroxidation enhanced coagulation process with respect to the dissolved organic carbon(DOC)*** KMnO_4 was dosed into both upstream and downstream of coagulation,namely in the proposed twoposition dosing mode,coagulation and KMnO_4 oxidation worked individually on the apparent DOC ***,compared to the KMnO_4 addition prior to or after coagulation,the two-position dosing mode dramatically alleviated membrane fouling and reduced fouling *** was attributed to the change of NOM characteristics as a result of KMnO_4 addition prior to coagulation and the presence of MnO_2 on membrane surface as a result of KMnO_4 addition prior to *** work may provide useful information for the application of KMnO_4 oxidation in the coagulation/ultrafiltration combined system.

关键词： Potassium permanganate Coagulation Dosing position Ultrafiltration Fouling

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Major ozonated autohemotherapy promotes the recovery of upper limb motor function in patients with acute cerebral infarction

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Neural Regeneration Research 2013年第5期8卷 461-468页

作者： xiaona wu Zhensheng Li Xiaoyan Liu Haiyan Peng Yongjun Huang Gaoquan Luo Kairun Peng Department of Neurology Guangzhou General Hospital of Guangzhou Military Command

Major ozonated autohemotherapy is classically used in treating ischemic disorder of the lower limbs In the present study, we performed major ozonated autohemotherapy treatment in patients with acute cerebral infarction, and assessed outcomes according to the U.S. National Institutes of Health Stroke Score, Modified Rankin Scale, and transcranial magnetic stimulation motor-evoked potential. Compared with the control group, the clinical total effective rate and the cortical potential rise rate of the upper limbs were significantly higher, the central motor conduction time of upper limb was significantly shorter, and the upper limb motor-evoked potential amplitude was significantly increased, in the ozone group. In the ozone group, the National Institutes of Health Stroke Score was positively correlated with the central motor conduction time and the motor-evoked potential amplitude of the upper limb. Central motor conduction time and motor-evoked potential amplitude of the upper limb may be effective indicators of motor-evoked potentials to assess upper limb motor function in cerebral infarct patients. Furthermore, major ozonated autohemotherapy may promote motor function recovery of the upper limb in patients with acute cerebral infarction.

关键词： neural regeneration clinical practice ozone cerebral infarction evoked potential motor upper limbs upper limb paralysis motor function central motor conduction time amplitude National Institutes of Health Stroke Score grants-supported paper photographs-containing paper neuroregenertion

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降钙素、血管内皮生长因子C在甲状腺髓样癌患者中的表达及临床意义

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癌症进展 2024年第8期22卷 914-916,928页

作者：张昆黄华武晓娜邢珂郑朝阳南阳市第二人民医院颈部甲状腺外科河南南阳473000 南阳医学高等专科学校基础医学部河南南阳473000

目的探讨降钙素(Ctn)、血管内皮生长因子C(VEGFC)在甲状腺髓样癌(MTC)患者中的表达及临床意义。方法选取82例MTC患者和71例健康体检者,分别作为观察组和对照组,采用酶联免疫吸附试验检测Ctn和VEGFC水平。比较两组受试者及不同TNM分期MT... 详细信息

目的探讨降钙素(Ctn)、血管内皮生长因子C(VEGFC)在甲状腺髓样癌(MTC)患者中的表达及临床意义。方法选取82例MTC患者和71例健康体检者,分别作为观察组和对照组,采用酶联免疫吸附试验检测Ctn和VEGFC水平。比较两组受试者及不同TNM分期MTC患者的Ctn、VEGFC水平。对MTC患者随访1年,根据随访情况分为预后良好组和预后不良组。比较预后良好组和预后不良组MTC患者的临床特征,采用Logistic回归模型分析MTC患者预后的影响因素。结果观察组患者Ctn、VEGFC水平均明显高于对照组,差异均有统计学意义(P﹤0.01)。Ⅲ~Ⅳ期MTC患者Ctn、VEGFC水平均明显高于Ⅰ~Ⅱ期患者,差异均有统计学意义(P﹤0.01)。预后良好组和预后不良组患者的TNM分期、淋巴结转移情况、Ctn水平、VEGFC水平比较,差异均有统计学意义(P﹤0.05)。多因素Logistic回归分析结果显示,TNM分期为Ⅲ~Ⅳ期、淋巴结转移、Ctn水平升高、VEGFC水平升高均是MTC患者预后不良的独立危险因素(P﹤0.05)。结论Ctn、VEGFC在MTC患者中表达均升高,且其表达水平与MTC的发生发展及预后密切相关。

关键词：甲状腺髓样癌降钙素血管内皮生长因子C 预后

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Shock-induced energy localization and reaction growth considering chemical-inclusions effects for crystalline explosives

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Defence Technology（防务技术） 2024年第3期33卷 278-294页

作者： Ruqin Liu Yanqing wu Xinjie Wang Fenglei Huang xiaona Huang Yushi Wen State Key Laboratory of Explosion Science and Technology Beijing Institute of TechnologyBeijing100081China School of Power and Mechanical Engineering Wuhan UniversityWuhan430072HubeiChina Institute of Chemical Materials China Academy of Engineering Physics(CAEP)Mianyang621999SichuanChina

Chemical inclusions significantly alter shock responses of crystalline explosives in macroscale gap experiments but their microscale dynamics origin remains *** shock-induced energy localization,overall physical responses,and reactions in a-1,3,5-trinitro-1,3,5-triazinane(a-RDX)crystal entrained various chemical inclusions were investigated by the multi-scale shock technique implemented in the reactive molecular dynamics *** indicated that energy localization and shock reaction were affected by the intrinsic factors within chemical inclusions,i.e.,phase states,chemical compositions,and *** atomic origin of chemical-inclusions effects on energy localization is dependent on the dynamics mechanism of interfacial molecules with free space volume,which includes homogeneous intermolecular compression,interfacial impact and shear,and void collapse and *** introducing various chemical inclusions,the initiation of those dynamics mechanisms triggers diverse decay rates of bulk RDX molecules and hereby impacts on growth speeds of final *** chemical inclusions can reduce the effectiveness of the void during the shock *** the shockwave velocity of 9 km/s,the parent RDX decay rate in RDX entrained amorphous carbon decreases the most and is about one fourth of that in RDX with a vacuum void,and solid HMX and TATB inclusions are more reactive than amorphous carbon but less reactive than dry air or acetone *** lessdense shocking system denotes the greater increases in local temperature and stress,the faster energy liberation,and the earlier final reaction into equilibrium,revealing more pronounced responses to the present intense *** quantitative models associated with the relative system density(RD_(sys))were proposed for indicating energy-localization mechanisms and evaluating initiation safety in the shocked crystalline ***_(sys)is defined by the density ratio of defective RDX to perfec

关键词： Shock responses Energy localization Crystalline explosives Chemical inclusions Reactive molecular dynamics

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Dual-extraction modeling:A multi-modal deeplearning architecture for phenotypic prediction and functional gene mining of complex traits

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Plant Communications 2024年第9期5卷 54-71页

作者： Yanlin Ren Chenhua wu He Zhou xiaona Hu Zhenyan Miao State Key Laboratory for Crop Stress Resistance and High-Efficiency Production Center of BioinformaticsCollege of Life SciencesNorthwest A&F UniversityYanglingShaanxi 712100China College of Chemistry&Pharmacy Northwest A&F UniversityYanglingShaanxi 712100China Key Laboratory of Biology and Genetics Improvement of Maize in Arid Area of Northwest Region Ministry of AgricultureNorthwest A&F UniversityYanglingShaanxi 712100China

Despite considerable advances in extracting crucial insights from bio-omics data to unravel the intricate mechanisms underlying complex traits,the absence of a universal multi-modal computational tool with robust interpretability for accurate phenotype prediction and identification of trait-associated genes remains a *** study introduces the dual-extraction modeling(DEM)approach,a multi-modal deep-learning architecture designed to extract representative features from heterogeneous omics datasets,enabling the prediction of complex trait *** comprehensive benchmarking experiments,we demonstrate the efficacy of DEM in classification and regression prediction of complex *** consistently exhibits superior accuracy,robustness,generalizability,and ***,we establish its effectiveness in predicting pleiotropic genes that influence both flowering time and rosette leaf number,underscoring its commendable *** addition,we have developed user-friendly software to facilitate seamless utilization of DEM’s *** summary,this study presents a state-of-the-art approach with the ability to effectively predict qualitative and quantitative traits and identify functional genes,confirming its potential as a valuable tool for exploring the genetic basis of complex traits.

关键词： deep learning complex traits multi-omics phenotypic prediction gene mining

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