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Frequency converting and digital modulation of light derived from lanthanide for signal encoding and logic computing

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InfoMat 2024年第7期6卷 102-113页

作者： Haisheng Chen Jiaying Shen xiaona du Songhua Cai Feng Guo Weng Fu Io Tianhong Zhou Zhengang Dong Taiyu Bian Jiaxing Guo Weiwei Liu Yang Zhang Zhenping Wu Jianhua Hao Institute of Modern Optics and Tianjin Key Laboratory of Micro-Scale Optical Information Science and Technology Nankai UniversityTianjinthe People's Republic of China State Key Laboratory of Information Photonics and Optical Communications&School of Science Beijing University of Posts and TelecommunicationsBeijingthe People's Republic of China Institute of Photoelectric Thin Film Devices and Technology College of Electronic Information and Optical EngineeringNankai UniversityTianjinthe People's Republic of China Department of Applied Physics The Hong Kong Polytechnic UniversityHung HomHong Kongthe People's Republic of China The Hong Kong Polytechnic University Shenzhen Research Institute Shenzhenthe People's Republic of China

Modulation of light underpins a central part of modern ***-ventional optical modulators based on refractive-index and absorption varia-tion in the presence of an electric field serve as the workhorse for diverse photonic ***,these approaches based on electro-refraction or electro-absorption effect impose limitations on frequency converting and signal ***-activated phosphors offer a promising plat-form for nonlinear frequency conversion with an abundant ***,we propose a novel approach to achieve frequency conversion and digital modula-tion of light signal by coupling lanthanide luminescence with an electrically responsive ferroelectric *** technological benefits of such paradigm-shifting solution are highlighted by demonstrating a quasi-continuous and enhancement of the lanthanide *** ability to locally manipulate light emission can convert digital information signals into visible waveforms,and visualize electrical logic and arithmetic *** proof-of-concept device exhibits perspectives for developing light-compatible logic *** results pave the way to design more controllable lanthanide photonics with desired opto-electronic coupling.

关键词： dynamic modulation ferroelectric thin film lanthanide luminescence signal encoding upconversion luminescence

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Textured Perovskite/Silicon Tandem Solar Cells Achieving Over 30% Efficiency Promoted by 4-Fluorobenzylamine Hydroiodide

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Nano-Micro Letters 2024年第9期16卷 557-570页

作者： Jingjing Liu Biao Shi Qiaojing Xu Yucheng Li Yuxiang Li Pengfei Liu Zetong SunLi Xuejiao Wang Cong Sun Wei Han Diannan Li Sanlong Wang Dekun Zhang Guangwu Li xiaona du Ying Zhao Xiaodan Zhang Renewable Energy Conversion and Storage Center Solar Energy Conversion CenterInstitute of Photoelectronic Thin Film Devices and TechnologyNankai UniversityTianjin 300350People’s Republic of China Key Laboratory of Photoelectronic Thin Film Devices and Technology of Tianjin Tianjin 300350People’s Republic of China Haihe Laboratory of Sustainable Chemical Transformations Tianjin 300192People’s Republic of China Engineering Research Center of Thin Film Photoelectronic Technology of Ministry of Education Tianjin 300350People’s Republic of China Collaborative Innovation Center of Chemical Science and Engineering(Tianjin) Tianjin 300072People’s Republic of China Center of Single‑Molecule Sciences Institute of Modern OpticsTianjin Key Laboratory of Micro‑Scale Optical Information Science and TechnologyCollege of Electronic Information and Optical EngineeringNankai University38 Tongyan RoadJinnan DistrictTianjin 300350People’s Republic of China Shenzhen Research Institute of Nankai University 16Th FloorYantian Science and Technology BuildingHaishan StreetYantian DistrictShenzhen 518083People’s Republic of China

Monolithic textured perovskite/silicon tandem solar cells(TSCs)are expected to achieve maximum light capture at the lowest cost,potentially exhibiting the best power conversion ***,it is challenging to fabricate high-quality perovskite films and preferred crystal orientation on commercially textured silicon substrates with micrometersize ***,we introduced a bulky organic molecule(4-fluorobenzylamine hydroiodide(F-PMAI))as a perovskite *** is found that F-PMAI can retard the crystallization process of perovskite film through hydrogen bond interaction between F^(−)and FA^(+)and reduce(111)facet surface energy due to enhanced adsorption energy of F-PMAI on the(111)***,the bulky molecular is extruded to the bottom and top of perovskite film after crystal growth,which can passivate interface defects through strong interaction between F-PMA+and undercoordinated Pb^(2+)/I^(−).As a result,the additive facilitates the formation of large perovskite grains and(111)preferred orientation with a reduced trap-state density,thereby promoting charge carrier transportation,and enhancing device performance and *** perovskite/silicon TSCs achieved a champion efficiency of 30.05%based on a silicon thin film tunneling *** addition,the devices exhibit excellent longterm thermal and light stability without *** work provides an effective strategy for achieving efficient and stable TSCs.

关键词： Perovskite crystallization (111)preferred orientation Defect passivation Perovskite/silicon tandem solar cells

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Local GABAergic Signaling within Sensory Ganglia Gates Peripheral Nociceptive Transmission

Local GABAergic Signaling within Sensory Ganglia Gates Perip...

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中国神经科学学会第十二届全国学术会议

作者： xiaona du Han hao Caixue Wang Xinmeng Li Hailin Zhang Nikita Gamper Department of Pharmacology Hebei Medical University Faculty of Biological Sciences University of Leeds

Objective It is generally assumed that integration of somatosensory information is a function of the central nervous system. We aim to describe fully functional GABAergic communication within rodent peripheral sensory ganglia and show that it can modulate transmission of pain-related signals from the peripheral sensory nerves to the CNS. Methods The expression of components of GABAergic circuit in DRG was tested by RT-PCR and immunofluorecent measurment. Sniffer patch and HPLC-MS methods were used to measure GABA release from DRG. Effects of DRG GABAergic circuit on pain behaviors were tested by focal application of GABA, or activating GABAergic neuron in rat/mice through optogenetic or chemogenentic approaches. Intraplantar injection of bradykinin was the method using to induce acute pain of animal. CFA injection and CCI model were used as chronic pain model. Thresholds of animal responding to mechanical and thermal stimulations were measured by Von Frey filament and Hargreaves tests. Results i) Sensory neurons express major proteins necessary for GABA synthesis and release. ii) Sensory neurons released GABA in response to depolarization. iii) In vivo focal infusion of GABA or GABA re-uptake inhibitor to sensory ganglia dramatically reduced acute peripherally-induced nociception and alleviated neuropathic and inflammatory pain. iv) Focal application of GABA receptor antagonists to sensory ganglia induced or exacerbated peripherally-induced nociception. v) Chemogenetic or optogenetic depolarization of GABAergic DRG neurons in vivo reduced acute and chronic peripherally-induced nociception. vi) GABA depolarized the majority of sensory neuron somata, yet produced a net inhibitory effect on the nociceptive transmission due to the filtering effect at nociceptive fiber t-junctions. Conclusion Our findings indicate that peripheral somatosensory ganglia represent a hitherto underappreciated site of somatosensory signal integration and offer a novel target for therapeutic i

关键词： DRG GABA pain transmission gate control theory

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养殖业扶贫对饲料企业发展影响分析

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中国饲料 2021年第16期 122-125页

作者：杜晓娜北京大学政府管理学院北京100871

养殖业作为饲料企业的下游企业对饲料企业的发展有着较大影响,随着脱贫攻坚任务的完成,很多地区的养殖业扶贫也趋于完善,使得这些地区的养殖业发展对饲料企业发展有较好的带动作用。本文从养殖业扶贫入手,对目前饲料企业与养殖业发展之... 详细信息

养殖业作为饲料企业的下游企业对饲料企业的发展有着较大影响,随着脱贫攻坚任务的完成,很多地区的养殖业扶贫也趋于完善,使得这些地区的养殖业发展对饲料企业发展有较好的带动作用。本文从养殖业扶贫入手,对目前饲料企业与养殖业发展之间的关系进行了深度分析,从推动饲料企业与养殖业的深度融合、打造饲料产业信息化发展态势、申请相关的政策支持及加强饲料企业内部创新等方面提出了发展路径,为实现饲料企业与养殖业更好地融合发展提供了思路。

关键词：养殖业扶贫扶贫政策饲料企业产业融合

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Effects of Conditional PDI Knockout in DRG Nociceptor Neurons on Mice Pain Behaviors

Effects of Conditional PDI Knockout in DRG Nociceptor Neuron...

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中国神经科学学会第十二届全国学术会议

作者： Yongxue zhang Zeyao Pu Fengwu Chen Yating An Wei Zhang Yi Wu Hailin Zhang xiaona du Deparment of Pharmacology Hebei Medical University Cyrus Tang Hematology Center Jiangsu Institute of Hematology Collaborative Innovation Center of Hematology Soochow University

Objective: PDI（PDIA1） is the prototype member of protein disulfide isomerases（PDIs） family. We found in the preliminary study that PDI（PDIA1） is highly expressed in neurons of dorsal root ganglia（DRG）. The present study is to explore the role of PDI in pain. Methods: We first used Cre-lox P recombinase system to conditional knockout PDI（PDI CKO） in DRG neurons. The PDI CKO mice were generated by crossing SNS-Cre mice with PDIfl/+ mice and efficiency of PDI conditional knockout in DRG was tested by immunofluorescence imaging and western blotting. Then we compared the pain behaviors of WT and PDI CKO mice under basic condition, acute pain and chronic pain situation. Results: The expression of PDI in DRG tissue of nociceptors-specific PDI knockout mice was markedly decreased. Compared to the WT mice, PDI CKO mice show increased mechanical pain thresholds. The nocifensive behaviors induced by a plantar injection of bradykinin were significantly reduced in PDI CKO mice. And the thermal hyperalgesia induced by a plantar injection of CFA was increased in PDI CKO ***: Conditional knockout PDI from nociceptive DRG neurons significantly reduces the sensitivity to mechanical stimulation and alleviates the pain behaviors of acute and chronic pain in mice. PDI should play an important role in generation of nociceptive sensation.

关键词： Protein disulfide isomerases PDI SNS DRG pain

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合欢对精神疾病的药理作用及机制研究进展

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药物评价研究 2024年第8期47卷 1929-1936页

作者：黄辰杰樊明理杜晓娜施学丽广西中医药大学研究生学院广西南宁530200 防城港市中医医院科教科广西防城港538000 广西中医药大学壮医药学院广西南宁530001

合欢Albizia julibrissin是一种药食两用的中药材,在临床中应用广泛。合欢的主要药用部位有合欢皮和合欢花,内含多种有效成分,具有抗炎、抗氧化、抗抑郁、镇静催眠等多种药理作用。研究显示合欢皮和合欢花及有效成分能通过调节神经递质... 详细信息

合欢Albizia julibrissin是一种药食两用的中药材,在临床中应用广泛。合欢的主要药用部位有合欢皮和合欢花,内含多种有效成分,具有抗炎、抗氧化、抗抑郁、镇静催眠等多种药理作用。研究显示合欢皮和合欢花及有效成分能通过调节神经递质表达、减轻氧化应激及炎症反应、调控相关信号通路等机制起到改善及治疗抑郁症、焦虑症等精神疾病的目的。主要对合欢皮、合欢花及有效成分抗抑郁和抗焦虑等治疗精神疾病的药理作用及机制的研究现状进行综述,旨在为合欢作为抗精神疾病药物的开发与应用提供参考。

关键词：合欢合欢皮合欢花精神疾病抑郁症焦虑症

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低温反硝化过程中pH对亚硝酸盐积累的影响

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环境化学 2016年第8期35卷 1657-1662页

作者：李思倩路立王芬杜晓娜季民天津大学环境科学与工程学院天津300072 天津市城市规划设计研究院天津300201

以乙酸钠为单一碳源,在C/N比为3、温度为12—14℃的低C/N比、低温条件下通过间歇试验研究p H对反硝化亚硝酸盐积累规律影响.试验结果发现,在C/N为3时,p H值在7—9的范围内都能形成亚硝酸盐积累.反应时间为60 min时,亚硝酸盐积累率最大可... 详细信息

以乙酸钠为单一碳源,在C/N比为3、温度为12—14℃的低C/N比、低温条件下通过间歇试验研究p H对反硝化亚硝酸盐积累规律影响.试验结果发现,在C/N为3时,p H值在7—9的范围内都能形成亚硝酸盐积累.反应时间为60 min时,亚硝酸盐积累率最大可达50%左右.低温SBR反应器连续试验研究表明,p H值为7.4±0.1和p H值为8.4±0.1时,序批式活性污泥法(SBR)出水亚硝酸盐积累率分别为51%和48%,取p H值为7.4±0.1条件下SBR反应器活性污泥进行酶活力测定发现,硝酸盐还原酶活力是亚硝酸盐还原酶活力的1.2倍,硝酸盐还原酶活力与亚硝酸盐还原酶活力对外界条件变化敏感程度不同,亚硝酸盐还原酶对外界条件变化更为敏感,其受到的抑制作用要大于硝酸盐还原酶,进而造成NO-2-N的积累.

关键词：反硝化亚硝酸盐积累 pH 酶活力

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EGF enhances the migration of cancer cells by up-regulation of TRPM7

EGF enhances the migration of cancer cells by up-regulation ...

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第九届全国钙信号和细胞功能研讨会

作者： Haixia Gao,Xingjuan Chen,xiaona du,Bingcai Guan,Yani Liu and Hailin Zhang The Key Laboratory of Neural and Vascular Biology,Ministry of Education The Key Laboratory of Pharmacology and Toxicology for New Drugs,Department of Pharmacology,Hebei Medical University,Shijiazhuang,China.

Ion channels involved in the migration of tumor cells that is required for their invasion and metastasis In this *** describe the interaction of TRPM7 channel and EGF in the migration of lung cancer *** TRPM7 currents in A549 cells were first characterized by means of electropbysiology,pharmacology and RNA *** found that removing Cafrom the extracellular solution not only potentiated a large inward current,but also abolished the outward rectification.200 uM 2-APB inhibited the outward and the inward TRPM7 current and at the same time restored the property

关键词： Cell=cancer Method=electrophysiology,cell biology Topic=migration

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2016—2020年北京市西城区出生缺陷人群监测资料分析

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中国优生与遗传杂志 2022年第12期30卷 2267-2269页

作者：杜晓娜胡天艳北京市西城区妇幼保健院北京100054

目的了解2016—2020年北京市西城区人群出生缺陷发生情况及影响因素。方法对2016—2020年期间在北京市西城区居住的产妇所分娩的胎婴儿资料进行分析。结果 2016—2020年共监测76155例胎婴儿,出生缺陷儿1715例,出生缺陷总发生率为22.52... 详细信息

目的了解2016—2020年北京市西城区人群出生缺陷发生情况及影响因素。方法对2016—2020年期间在北京市西城区居住的产妇所分娩的胎婴儿资料进行分析。结果 2016—2020年共监测76155例胎婴儿,出生缺陷儿1715例,出生缺陷总发生率为22.52‰,出生缺陷发生率呈逐年上升趋势。2016—2020年(2017年除外),位于前三位的出生缺陷均为先天性心脏病、外耳其他畸形和隐睾。男性出生缺陷儿发生率(24.25‰)高于女性(20.67‰),35岁及以上产妇分娩的胎婴儿出生缺陷发生率(26.34‰)高于35岁以下产妇(21.40‰),母亲为本市的出生缺陷儿发生率(25.01‰)高于母亲为外地者(17.90‰),差异有统计学意义。死胎死产儿和42天内死亡的婴儿出生缺陷发生率明显增加,分别为280.00‰、157.89‰。结论 2016—2020年,北京市西城区出生缺陷发生率呈逐年增高趋势,先天性心脏病发生率始终位于首位。男性胎婴儿、母亲为本市户籍及35岁及以上产妇分娩的胎婴儿出生缺陷发生率明显增加。出生缺陷是引起胎婴儿死亡的主要原因。

关键词：出生缺陷发生率人群北京市

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血浆D-二聚体检测对下肢深静脉血栓早期的诊断价值

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中国卫生标准管理 2017年第14期8卷 101-103页

作者：郭桂军杜晓娜乐陵市人民医院检验科山东乐陵253600

目的研究血浆D-二聚体检测诊断下肢深静脉血栓的早期效果。方法选取我院2015年4月—2017年4月收治的58例疑似下肢深静脉血栓者以及同期同例数健康者作为研究对象,疑似下肢深静脉血栓者为观察组,健康者为对照组,分析两组研究对象D-二聚... 详细信息

目的研究血浆D-二聚体检测诊断下肢深静脉血栓的早期效果。方法选取我院2015年4月—2017年4月收治的58例疑似下肢深静脉血栓者以及同期同例数健康者作为研究对象,疑似下肢深静脉血栓者为观察组,健康者为对照组,分析两组研究对象D-二聚体含量的差异。结果观察组对比对照组在D-二聚体含量上差异显著,具有统计学意义(P<0.05)。结论 D-二聚体是体内血栓状态及血栓形成的重要指标,本次研究发现疑似病例的D-二聚体含量与健康者相比差异显著,因此D-二聚体是判断下肢深静脉血栓的重要参考标准。

关键词：血浆D-二聚体下肢深静脉血栓早期诊断

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