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Hard-rock tunnel lithology identification using multiscale dilated convolutional attention network based on tunnel face images

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Frontiers of Structural and Civil Engineering 2023年第12期17卷 1796-1812页

作者： Wenjun ZHANG Wuqi ZHANG Gaole ZHANG Jun HUANG Minggeng LI Xiaohui WANG Fei YE xiaoming guan School of Civil Engineering Tianjin UniversityTianjin 300350China School of Civil Engineering and Architecture Guangxi UniversityNanning 530004China Jiangxi Communications Design and Research Institute Co. Ltd.Nanchang 330000China China Railway 18th Bureau Group Co. Ltd.Tianjin 300222China School of Highway Chang'an UniversityXi'an 710064China School of Civil Engineering Qingdao University of TechnologyQingdao 266033China

For real-time classification of rock-masses in hard-rock tunnels,quick determination of the rock lithology on the tunnel face during construction is *** by current breakthroughs in artificial intelligence technology in machine vision,a new automatic detection approach for classifying tunnel lithology based on tunnel face images was *** method benefits from residual learning for training a deep convolutional neural network(DCNN),and a multi-scale dilated convolutional attention block is *** block with different dilation rates can provide various receptive fields,and thus it can extract multi-scale ***,the attention mechanism is utilized to select the salient features adaptively and further improve the performance of the *** this study,an initial image data set made up of photographs of tunnel faces consisting of basalt,granite,siltstone,and tuff was first *** classifying and enhancing the training,validation,and testing data sets,a new image data set was generated.A comparison of the experimental findings demonstrated that the suggested approach outperforms previous classifiers in terms of various indicators,including accuracy,precision,recall,F1-score,and computing ***,a visualization analysis was performed to explain the process of the network in the classification of tunnel lithology through feature ***,this study demonstrates the potential of using artificial intelligence methods for in situ rock lithology classification utilizing geological images of the tunnel face.

关键词： hard-rock tunnel face intelligent lithology identification multi-scale dilated convolutional attention network image classification deep learning

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Single incision laparoscopic myomectomy in pregnancy

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Gynecology and Obstetrics Clinical Medicine 2022年第2期2卷 96-99页

作者： Brooke Thigpen Tara Harris Sowmya Sunkara xiaoming guan Department of Obstetrics and Gynecology Baylor College of MedicineHoustonTXUSA

The prevalence of fibroids in pregnancy ranges from 2%to 10%.About 10%of these fibroids lead to complications in pregnancy including pain,intrauterine growth restriction,morbidly adherent placentation,placental abruption,dystocia,and postpartum hemorrhage.1 Pain is the most common complication of fibroids during pregnancy.2 Causes of pain include increased pressure on the fibroid itself,torsion of a pedunculated fibroid,and degeneration due to rapid fibroid growth.2 Pain can first be managed conservatively with rest,hydration,and analgesics;however,if pain is refractory to conservative management,surgical management with myomectomy may be indicated.3 Spyropoulou K et al.4 performed a review of the literature regarding myomectomy in *** review found that majority of myomectomies in pregnancy were performed via laparotomy with overall favorable pregnancy outcomes and few complications,concluding that myomectomy in pregnancy is safe in cases not responding to conservative management.

关键词： conservative torsion hydration

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The evolution of sacrocolpopexy and development of novel techniques via natural orifice transluminal endoscopic surgery

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Gynecology and Obstetrics Clinical Medicine 2021年第2期1卷 68-69页

作者： Tamisa Koythong xiaoming guan Division of Minimally Invasive Gynecology Department of Obstetrics and GynecologyBaylor College of MedicineHoustonTXUSA

Prolapse of one or more pelvic organs through the vagina,such as the uterus,bladder,or rectum,is an increasingly common occurrence in the aging female population,with rates approaching 60%of parous women.1 Its associated symptoms of vaginal bulge or bladder,bowel,or sexual dysfunction can drastically affect a woman's quality of *** surgical options for the treatment pelvic organ prolapse exist and may involve autologous tissue repair or the use of biological or synthetic *** sacrocolpopexy,first described in 1957 by Arthure and Savage,involves using the sacrum as a point of support for the vaginal apex.2 The technique was further refined by Huguier and Scali by the incorporation of a graft to improve tissue strength and to improve postoperative anatomical cure rates.3 For many surgeons,abdominal sacrocolpopexy is the preferred surgical technique as it has demonstrated superior outcomes with higher postoperative success rates through restoration of normal anatomy and lower rates of prolapse recurrence and postoperative dyspareunia.

关键词： Sacrocolpopexy Endoscopic surgery Transvaginal

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Translation considerations of drug discovery for Parkinson’s disease: Challenges and Opportunities

Translation considerations of drug discovery for Parkinson’...

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中国神经科学学会第十二届全国学术会议

作者： xiaoming guan Neurodegeneration DPU Glaxo Smith Kline R＆D China

Parkinson’s disease（PD） is a highly debilitating neurodegenerative disease, affecting millions worldwide. As the world population ages, the incidence of PD increases rapidly. Despite great success in developing symptomatic treatment of motor dysfunctions, duration of efficacy of such drugs is limited and significant side effects often take place over period of treatment. To date, no medicines are available that slow or halt the progression of PD by intervening the underlying disease pathogenesis. The lack of success in developing disease modifying medicines are due to a number of challenges, including lack of validated drug targets, translatable PD animal models, qualified biomarkers for disease mechanisms and robust/sensitive clinical efficacy readout. Recent advancement in human genetics, biomarker discovery and innovative clinical trial design/measurement provided exciting opportunities for developing next generation of transformative medicines for PD.

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Evaluation of CD24 as a marker to rapidly define the mesenchymal stem cell phenotype and its differentiation in human nucleus pulposus

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Chinese Medical Journal 2014年第8期127卷 1474-1481页

作者： guan xiaoming Ma Xun Zhang Li Feng Haoyu Ma Zhuo Department of Orthopaedics Surgery Second Hospital Shanxi Medical University Taiyuan Shanxi 030001 China Department of Orthopaedics Surgery Da Yi Hospital Shanxi Medical University Taiyuan Shanxi 030032 China

Background Recent studies have indicated that human nucleus pulposus contain mesenchymal stem cells （NP-MSCs）. However, the immunophenotypic variation of NP-MSCs in vitro was unclear. The present study was conducted to address the immunophenotypic variation of mesenchymal stem cells in nucleus pulposus under continuous proliferation in vitro and show the difference between mesenchymal stem cells and nucleus pulposus cell. Methods Tissue samples were obtained from thoracolumbar burst fracture patients and degenerative disc disease patients who underwent discectomy and fusion procedures. Flow cytometric and laser scanning confocal microscope （LSCM） were used to detect the variation of mesenchymal stem cells in nucleus pulposus which were expressing CD105 and CD24 in condition with or without transforming growth factor [31 （TGF-131）. Results More than 90% of the analyzed primary cells of mesenchymal stem cells in nucleus pulposus fulfilled the general immunophenotyping criteria for MSCs, such as CD44, CD105 and CD29, but the marker of mature NP cells characterized as CD24 was negative. In continuous cultures, the proportion of mesenchymal stem cells which were expressing CD44, CD105 and CD29 in nucleus pulposus gradually decreased. The mesenchymal stem cells in nucleus pulposus cells were positive for CD105 and CD29, with slight positivity for CD44. The CD24 expression gradually increased in proliferation. Bi- parametric flow cytometry and laser scanning confocal microscopy confirmed the presence of cells which were expressing CD105 and CD24 independently, and only a small part of cells expressed both CD105 and CD24 simultaneously. TGF-{31 could stimulate mesenchymal stem cells in nucleus pulposus to express CD24. Conclusions Non-degenerative and degenerative NP contains mesechymal stem cells. The variation of CD24 can be used as a marker to identify the NP-MSCs differentiation into NP-like cells.

关键词： CD24 mesenchymal stem cell nucleus pulposus

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劳动者技能、劳动力流动与收入再分配

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财经科学 2006年第2期 31-37页

作者：管晓明南开大学经济学院经济研究所

二元经济下劳动力的流动和收入再分配是经济学界长期关注的焦点问题之一。本文从标准的刘易斯模型所体现的经济及制度环境入手建立模型,分析劳动者技能、劳动力流动与收入再分配三者之间的关系,对照中国当前实际指明问题所在并提供相应... 详细信息

二元经济下劳动力的流动和收入再分配是经济学界长期关注的焦点问题之一。本文从标准的刘易斯模型所体现的经济及制度环境入手建立模型,分析劳动者技能、劳动力流动与收入再分配三者之间的关系,对照中国当前实际指明问题所在并提供相应的对策建议,为我国当前及今后相当长时期妥善处理劳动力流动及再分配问题提供了参考。

关键词：劳动者技能劳动力流动收入再分配

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从算法治理到治理算法:国家治理现代化的技术审视——基于技术政治学的分析视角

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甘肃行政学院学报 2023年第6期 49-67,125,126页

作者：关晓铭黄淮学院经济与管理学院河南驻马店463000

不管是深刻认知社会的规范而系统的学术研究,还是追求国家治理效能的持续改善,都需要从现代政治学,特别是技术政治学的视角对算法治理进行深入而系统的探究。算法治理具有两面性,既通过数据化、标准化和流程化等建构逻辑,强化、提升国... 详细信息

不管是深刻认知社会的规范而系统的学术研究,还是追求国家治理效能的持续改善,都需要从现代政治学,特别是技术政治学的视角对算法治理进行深入而系统的探究。算法治理具有两面性,既通过数据化、标准化和流程化等建构逻辑,强化、提升国家治理的效能,也带来个体主体性的消解、国家权威性的弱化和社会歧视性的出现等诸多治理风险。通过对算法治理的风险研判和因果循证,本文建议为规避算法治理的内生和衍生风险、增强算法治理的实效性和针对性,治理算法应该以协商民主路径赋予公民更多机会、权利和资源参与决策和议程。

关键词：算法治理国家权威社会歧视日常领域协商民主

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项目制:国家治理现代化的技术选择--技术政治学的视角

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甘肃行政学院学报 2020年第5期 87-102,127页

作者：关晓铭黄淮学院经济与管理学院河南驻马店463000

不管是社会学还是公共管理学都强调项目制是国家为适应现代社会而采取的治理策略,却忽视了项目制的内在属性,即项目制是一种技术。项目制的技术逻辑不仅能够协调多元项目主体的一致性行动,而且能够提高国家治理的科学化和精细化水平,从... 详细信息

不管是社会学还是公共管理学都强调项目制是国家为适应现代社会而采取的治理策略,却忽视了项目制的内在属性,即项目制是一种技术。项目制的技术逻辑不仅能够协调多元项目主体的一致性行动,而且能够提高国家治理的科学化和精细化水平,从而提高公共事务运作的标准化、专业性和效率化,避免了财政资源配置的随意行为。然而,由于技术自主、专家陷阱和结构替代的限制,项目制实施效果远未达到预期并且经常受到批判。通过对项目制技术属性和实践偏离的深度剖析,深刻地意识到为避免项目制的技术风险、增强项目制的实效性,项目制运作应该纳入公民参与。

关键词：项目制技术自主专家陷阱结构替代公民参与

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脊髓型颈椎病手术入路及减压融合方式的选择策略

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中华骨科杂志 2019年第23期39卷 1478-1484页

作者：关晓明马迅山西白求恩医院(山西医学科学院)骨科太原030032

脊髓型颈椎病是骨科常见病及多发病,尤其是多节段脊髓型颈椎病,致病因素多样,临床症状重,影像学表现复杂,大多伴有严重的神经功能损害,严重影响患者的生活质量,部分患者甚至在轻微外伤后即出现严重的颈脊髓损伤症状,危及生命.因此需早诊... 详细信息

脊髓型颈椎病是骨科常见病及多发病,尤其是多节段脊髓型颈椎病,致病因素多样,临床症状重,影像学表现复杂,大多伴有严重的神经功能损害,严重影响患者的生活质量,部分患者甚至在轻微外伤后即出现严重的颈脊髓损伤症状,危及生命.因此需早诊断,早治疗,手术治疗是目前最为有效的方法,可以有效解除脊髓压迫因素,重建颈椎功能稳定性.但是如何选择手术入路及减压融合方式是临床争议的焦点.脊髓型颈椎病手术治疗的首要目的是彻底解除对脊髓的压迫,因此结合影像学特点决定减压和重建术式是手术成功的关键.致压因素主要位于脊髓前方,以椎间盘突出、轻度骨赘或局限性后纵韧带骨化为主,病变节段少,致压范围小,颈椎后凸或局部后凸畸形,手术易于切除致压物和需要矫正矢状位失衡者,可以采用前方入路;减压融合方式可选择经椎间隙、经椎体次全切或混合减压方式,另外为了更多地保留颈椎活动功能可以选择人工椎间盘置换和融合固定相结合的方式.致压因素主要位于脊髓后方,黄韧带肥厚或骨化,先天性发育性椎管狭窄,脊髓前方致压因素多,范围大,病变节段长,难以从前方彻底切除,前路手术风险极大者,可采用后方入路;虽然后路手术为间接减压,但借助脊髓后移能起到改善神经功能的作用,并发症少,安全性相对较高.另外经后入路还可以利用椎弓根或侧块螺钉达到减压效果,并矫正后凸畸形.两种入路及相关减压方式,均有各自的手术绝对适应证与相对适应证.前后路联合手术具有彻底减压和坚强固定的优势,但创伤大、风险高,临床应用需谨慎.无论如何选择入路,均应以完善的影像学资料结合临床症状与体征为基础,明确脊髓的致压病理因素、脊髓损害的轻重、受压范围的大小和责任节段,进而制定个体化手术方案.

关键词：脊髓型颈椎病后纵韧带骨化手术入路病变节段黄韧带肥厚后凸畸形减压效果轻微外伤

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圆外区域求解Helmholtz方程

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高等学校计算数学学报 2006年第4期28卷 289-298页

作者：关晓明林伟中山大学数学系中山大学数学系广州 510275

1引言许多科学和工程计算问题都可以归结为无界区域上的偏微分方程边值问题．而求解椭圆方程边值问题的常用技术是有限元方法,可是对于无界区域,在用有限元方法求解时,往往遇到困难．最简单的办法显然是直接略去区域的无界部分求解,但... 详细信息

1引言许多科学和工程计算问题都可以归结为无界区域上的偏微分方程边值问题．而求解椭圆方程边值问题的常用技术是有限元方法,可是对于无界区域,在用有限元方法求解时,往往遇到困难．最简单的办法显然是直接略去区域的无界部分求解,但这样做或者导致过低的计算精度,或者要付出很高的计算代价．边界归化,即将求解偏微分方程边值问题转化为边界积分方程,是求解某些无界区域问题的强有力的手段．自70年代以来,有限元和

关键词： wavelet Helmholtz equation natural boundary element method numerical solution.

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