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MOOC视频讲座中的元话语:与大学传统讲座及学科特性的对比分析

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Chinese Journal of Applied Linguistics 2024年第2期47卷 309-331,366页

作者：于晓莉美国教育学院

基于Hyland(2018)的元话语人际关系模型,本研究探讨了MOOC视频讲师对元话语的使用,并将其与传统大学讲师的使用进行了比较。本研究还调查了MOOC视频讲座中元话语的学科差异。MOOC语料库由16个MOOC组成,涉及三个学科领域,包括艺术与人文... 详细信息

基于Hyland(2018)的元话语人际关系模型,本研究探讨了MOOC视频讲师对元话语的使用,并将其与传统大学讲师的使用进行了比较。本研究还调查了MOOC视频讲座中元话语的学科差异。MOOC语料库由16个MOOC组成,涉及三个学科领域,包括艺术与人文科学、工程与物理科学以及社会科学。研究结果表明,尽管存在细微差别,但MOOC语料库中出现频率最高的元话语与大学讲座中的元话语模式相似,这揭示了MOOC与传统面对面讲座在使用元话语方面的显著相似性。然而,不同的教学情境和师生关系确实造成了元话语使用的差异。总体而言,与大学讲师相比,MOOC视频讲师使用了更多的交互式元话语,但使用的交互式元话语较少。从跨学科角度看,元话语在MOOC视频讲座中的使用在很大程度上受到学科特点的影响。包含更多特定学科内容、需要密集认知努力的MOOC往往使用更多互动元话语和参与标记;而对于可能包含更多视角而非基本事实的MOOC,似乎更频繁地使用助推器和态度标记。本研究对各学科在运用元话语方面所呈现的差异,深入探讨了其潜在原因与具体目的。

关键词：元话语人际模型学术口语话语 MOOC 学科差异

医共体模式下“互联网+安宁疗护”的实践与思考

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中国护理管理 2024年第5期24卷 765-768页

作者：乐英南俞晓利钱颖浙江省舟山市普陀区人民医院重症医学科浙江省舟山市316100 浙江大学医学院附属邵逸夫医院血液科

目的:探索医共体模式下“互联网+安宁疗护”的服务模式,以提高舟山市海岛地区终末期患者或老年患者生命末期的生活质量。方法:通过组建安宁疗护专业团队,开展医共体模式同质化管理,发挥“互联网+”优势,实现患者从医疗机构到居家线上安... 详细信息

目的:探索医共体模式下“互联网+安宁疗护”的服务模式,以提高舟山市海岛地区终末期患者或老年患者生命末期的生活质量。方法:通过组建安宁疗护专业团队,开展医共体模式同质化管理,发挥“互联网+”优势,实现患者从医疗机构到居家线上安宁疗护的身体、心理、精神及社会支持等多方位的照护和人文关怀。结果:截至2023年9月30日,为103位患者及患者家属提供了安宁疗护服务,患者及家属的满意度达98.8%。结论:医共体模式下“互联网+安宁疗护”模式在实践中显示出其在海岛地区的强大适用性,值得未来进一步推广。

关键词：医共体模式互联网+安宁疗护海岛地区实践与思考

A three-parameter logistic regression model

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Statistical Theory and Related Fields 2021年第3期5卷 265-274页

作者： xiaoli yu Shaoting Li Jiahua Chen School of Mathematics and Statistics University of British ColumbiaVancouverCanada School of Mathematics and Statistics Dongbei University of Finance and EconomicsDalianPeople’s Republic of China School of Mathematics and Statistics Yunnan UniversityKunmingPeople’s Republic of China

Dose–response experiments and data analyses are often carried out according to an optimal design under a model assumption.A two-parameter logistic model is often used because of its nice mathematical properties and plausible stochastic response mechanisms.There is an extensive literature on its optimal designs and data analysis strategies.However,a model is at best a good approximation in a real-world application,and researchers must be aware of the risk of model mis-specification.In this paper,we investigate the effectiveness of the sequential EDdesign,the D-optimal design,and the up-and-down design under the three-parameter logistic regression model,and we develop a numerical method for the parameter estimation.Simulations show that the combination of the proposed model and the data analysis strategy performs well.When the logistic model is correct,this more complex model has hardly any efficiency loss.The three-parameter logistic model works better than the two-parameter logistic model in the presence of model mis-specification.

关键词： effective dose level optimal design sequential ED-design up-and-down design vertex direction method

Analysis of a 1 kW organic Rankine cycle using a scroll expander for engine coolant and exhaust heat recovery

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Frontiers in Energy 2017年第4期11卷 527-534页

作者： Yiji LU Anthony Paul ROSKILLY Long JIANG Longfei CHEN xiaoli yu Sir Joseph Swan Centre for Energy Research Newcastle University Newcastle NE1 7RU UK Institute of Refrigeration and Cryogenics Shanghai Jiao TongUniversity Shanghai 200240 China School of Energy and Power Engineering Beihang University Beijing 100191 China Department of Energy Engineering Zhejiang University Hangzhou310027 China

The development of engine waste heat recov- ery technologies attracts ever increasing interests due to the rising strict policy requirements and environmental con- cerns. This paper presented the study of engine coolant and exhaust heat recovery using organic Rankine cycle （ORC）. Eight working fluids were selected to evaluate and compare the performance of the integrated waste heat recovery system. Rather than the conventional engine ORC system mainly focusing on the utilization of exhaust energy, this work proposed to fully use the engine coolant energy by changing the designed parameters of the ORC system. The case study selected a small engine as the heat source to drive the ORC system using a scroll expander for power production. The evaluation results suggest that under the engine rated condition, the solution to fully recover the engine coolant energy can achieve a higher power generation performance than that of the conven- tional engine ORC system. The results suggest that adding a recuperator to the ORC system can potentially improve the system performance when the working fluids are dry and the overall dumped heat demand of the system can be reduced by 12% under optimal conditions. When the ORC evaporating and condensing temperature are respectivelyset at 85℃ and 30℃, the integrated engine waste heat recovery system can improve the overall system efficiency by 9.3% with R600, R600a or n-Pentane as the working fluid.

关键词： organic Rankine cycle scroll expander cool-ant and exhaust recovery internal combustion engine

Metagenomic insights into the effects of submerged plants on functional potential of microbial communities in wetland sediments

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Marine Life Science & Technology 2021年第4期3卷 405-415页

作者： Binhao Wang Xiafei Zheng Hangjun Zhang xiaoli yu Yingli Lian Xueqin Yang Huang yu Ruiwen Hu Zhili He Fanshu Xiao Qingyun Yan Environmental Microbiomics Research Center School of Environmental Science and EngineeringSouthern Marine Science and Engineering Guangdong Laboratory(Zhuhai)Sun Yat-Sen UniversityGuangzhou 510006China Institute of Soil and Water Resources and Environmental Science College of Environmental and Resource SciencesZhejiang UniversityHangzhou 310058China College of Life and Environmental Sciences Hangzhou Normal UniversityHangzhou 310036China College of Agronomy Hunan Agricultural UniversityChangsha 410128China

Submerged plants in wetlands play important roles as ecosystem engineers to improve self-purification and promote elemental cycling.However,their effects on the functional capacity of microbial communities in wetland sediments remain poorly understood.Here,we provide detailed metagenomic insights into the biogeochemical potential of microbial communities in wetland sediments with and without submerged plants(i.e.,Vallisneria natans).A large number of functional genes involved in carbon(C),nitrogen(N)and sulfur(S)cycling were detected in the wetland sediments.However,most functional genes showed higher abundance in sediments with submerged plants than in those without plants.Based on the comparison of annotated functional genes in the N and S cycling databases(i.e.,NCycDB and SCycDB),we found that genes involved in nitrogen fixation(e.g.,nifD/H/K/W),assimilatory nitrate reduction(e.g.,nasA and nirA),denitrification(e.g.,nirK/S and nosZ),assimilatory sulfate reduction(e.g.,cysD/H/J/N/Q and sir),and sulfur oxidation(e.g.,glpE,soeA,sqr and sseA)were significantly higher(correctedp<0.05)in vegetated vs.unvegetated sediments.This could be mainly driven by environmental factors including total phosphorus,total nitrogen,and C:N ratio.The binning of metagenomes further revealed that some archaeal taxa could have the potential of methane metabolism including hydrogenotrophic,acetoclastic,and methylotrophic methanogenesis,which are crucial to the wetland methane budget and carbon cycling.This study opens a new avenue for linking submerged plants with microbial functions,and has further implications for understanding global carbon,nitrogen and sulfur cycling in wetland ecosystems.

关键词： Submerged plants Metagenome Elemental cycling Methanogenesis Verstraetearchaeota

Environmental selection and evolutionary process jointly shape genomic and functional profiles of mangrove rhizosphere microbiomes

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mLife 2023年第3期2卷 253-266页

作者： xiaoli yu Qichao Tu Jihua Liu Yisheng Peng Cheng Wang Fanshu Xiao Yingli Lian Xueqin Yang Ruiwen Hu Huang yu Lu Qian Daoming Wu Ziying He Longfei Shu Qiang He yun Tian Faming Wang Shanquan Wang Bo Wu Zhijian Huang Jianguo He Qingyun Yan Zhili He State Key Laboratory for Biocontrol Southern Marine Science and Engineering Guangdong Laboratory(Zhuhai)School of Environmental Science and EngineeringEnvironmental Microbiomics Research CenterSun Yat‐sen UniversityGuangzhouChina Institute of Marine Science and Technology Shandong UniversityQingdaoChina College of Forestry&Landscape Architecture South China Agricultural UniversityGuangzhouChina Southern Marine Science and Engineering Guangdong Laboratory(Zhuhai) School of Marine ScienceSun Yat‐sen UniversityGuangzhouChina Department of Civil and Environmental Engineering The University of TennesseeKnoxvilleTennesseeUSA Key Laboratory of the Ministry of Education for Coastal and Wetland Ecosystems School of Life SciencesXiamen UniversityXiamenChina xiaoliang Research Station for Tropical Coastal Ecosystems and Key Laboratory of Vegetation Restoration and Management of Degraded Ecosystems South China Botanical GardenChinese Academy of SciencesGuangzhouChina School of Life Sciences Sun Yat‐sen UniversityGuangzhouChina

Mangrove reforestation with introduced species has been an important strategy to restore mangrove ecosystem functioning.However,how such activities affect microbially driven methane(CH4),nitrogen(N),and sulfur(S)cycling of rhizosphere microbiomes remains unclear.To understand the effect of environmental selection and the evolutionary process on microbially driven biogeochemical cycles in native and introduced mangrove rhizospheres,we analyzed key genomic and functional profiles of rhizosphere microbiomes from native and introduced mangrove species by metagenome sequencing technologies.Compared with the native mangrove(Kandelia obovata,KO),the introduced mangrove(Sonneratia apetala,SA)rhizosphere microbiome had significantly(p<0.05)higher average genome size(AGS)(5.8 vs.5.5 Mb),average 16S ribosomal RNA gene copy number(3.5 vs.3.1),relative abundances of mobile genetic elements,and functional diversity in terms of the Shannon index(7.88 vs.7.84)but lower functional potentials involved in CH4 cycling(e.g.,mcrABCDG and pmoABC),N2 fixation(nifHDK),and inorganic S cycling(dsrAB,dsrC,dsrMKJOP,soxB,sqr,and fccAB).Similar results were also observed from the recovered Proteobacterial metagenome-assembled genomes with a higher AGS and distinct functions in the introduced mangrove rhizosphere.Additionally,salinity and ammonium were identified as the main environmental drivers of functional profiles of mangrove rhizosphere microbiomes through deterministic processes.This study advances our understanding of microbially mediated biogeochemical cycling of CH_(4),N,and S in the mangrove rhizosphere and provides novel insights into the influence of environmental selection and evolutionary processes on ecosystem functions,which has important implications for future mangrove reforestation.

关键词： average genome size functional potential mangrove rhizosphere metagenome metagenome-assembled genome

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基于约束理论优化医院互联网诊疗流程的研究

江苏卫生事业管理 2024年第2期35卷 167-169,173页

作者：俞小莉翁卫群南通市第一人民医院门诊部江苏南通226001

目的:探讨基于约束理论优化医院互联网诊疗就医流程,分析实施效果。方法:选取南通市第一人民医院2022年9月-2023年3月门诊线上线下就诊患者为研究对象。应用约束理论调研分析患者使用医院互联网诊疗平台现状和影响因素,并根据调研结果... 详细信息

目的:探讨基于约束理论优化医院互联网诊疗就医流程,分析实施效果。方法:选取南通市第一人民医院2022年9月-2023年3月门诊线上线下就诊患者为研究对象。应用约束理论调研分析患者使用医院互联网诊疗平台现状和影响因素,并根据调研结果优化互联网诊疗流程,比较优化前后互联网诊疗平台使用率。结果:流程优化后,互联网诊疗平台使用率由0.39%提高至4.63%;医生接诊响应时间由37.31±4.11降至10.37±3.60分钟;患者互联网医院就诊满意度由79.03±5.16提高至94.89±7.15,差异均有统计学意义(P <0.001)。结论:基于约束理论优化医院互联网诊疗就医流程,可以明显提高互联网诊疗使用率,缩短医生接诊响应时间,提升患者就医体验。

关键词：约束理论互联网诊疗就医流程优化

Involvement of GluA1-AMPAR-mediated LTP in time-dependent decline of cognitive function in rats with temporal lobe epilepsy

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Acta Epileptologica 2021年第1期3卷 7-14页

作者： Xiaoqing Luo xiaoli yu Jufang Liang Ruidi Sun Cheng Li Jun Jiang Department of Electrophysiology Wuhan Children’s Hospital(Wuhan Maternal and Child Healthcare Hospital)Tongji Medical CollegeHuazhong University of Science and TechnologyNo.100 of Hong Kong RoadJiang’an District430016 WuhanChina

Background:Cognitive impairment is one of the common comorbidities in patients with temporal lobe epilepsy(TLE),but the underlying mechanisms remain largely unknown.Previous studies have found significant decay of hippocampal long-term potentiation(LTP)in TLE rats with cognitive impairment.As the activation ofα-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptors(AMPARs)is responsible for LTP formation and learning and memory,we investigated whether AMPARs are involved in the LTP inhibition and the TLE-associated cognitive impairments.Methods:TLE rat model was established by intraperitoneal injection of lithium chloride-pilocarpine on postnatal day 21(P21).Learning and memory performance,hippocampal expression of membrane GluA1-AMPARs,and hippocampal LTP were tested by behavioral tests,western blotting,and field potential recording,respectively,at 1,5 and 13 weeks after induction of status epilepticu(SE).Finally,the effects of(S)-AMPA,an agonist of AMPARs,on LTP and cognitive function were tested.Results:Results of behavioral tests revealed an time-dependent decline in the learning and memory of TLE rats when compared to the age-matched controls at week 5 and 13,rather than at week 1 after the induction of SE.Western blotting showed that the hippocampal expression of membrane GluA1 was significantly decreased in a time-dependent manner in the TLE rats when compared to the age-matched controls at weeks 5 and 13,rather than at week 1 after the induction of SE.Similarly,the hippocampal LTP was inhibited in a time-dependent manner in TLE rats at weeks 5 and 13,rather than at week 1 after the induction of SE.Moreover,intra-hippocampal injection of(S)-AMPA ameliorated the deficits in learning as well as spatial and emotional memory in a dosedependent manner,and partially reversed the inhibition of CA1 LTP in the TLE rats at week 13 after the induction of SE.Conclusions:The reduced expression of hippocampal membrane GluA1 may be involved in LTP decay in CA1 and cognition impairment in TLE rats.

关键词： Cognitive impairment Temporal lobe epilepsy Long-term potentiation Hippocampus AMPA receptor

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大功率燃料电池建模与电压一致性分析

储能科学与技术 2024年第3期13卷 952-962页

作者：包敏杰俞小莉黄瑞陈俊玄陈孝炀郅文彬浙江大学工程师学院浙江杭州310015 浙江大学能源工程学院浙江杭州310027 浙江省汽车智能热管理科学与技术重点实验室浙江台州317299

随着燃料电池堆朝着大功率发展,其工作时单体间的不一致性更加明显,长时间处于恶劣工作条件的单体寿命会明显短于其他单体,并导致电池堆的寿命大幅缩减。为探究不同运行参数对大功率燃料电池单体工作性能一致性的影响规律,首先,建立了... 详细信息

随着燃料电池堆朝着大功率发展,其工作时单体间的不一致性更加明显,长时间处于恶劣工作条件的单体寿命会明显短于其他单体,并导致电池堆的寿命大幅缩减。为探究不同运行参数对大功率燃料电池单体工作性能一致性的影响规律,首先,建立了包括流体网络模型、燃料电池电压模型和燃料电池热阻模型三个部分的110 kW大功率燃料电池模型。其次,开展燃料电池稳态试验,对所建立的燃料电池模型进行试验验证,仿真与试验结果误差在5%以内。最后,基于模型仿真,以电压最大偏差率为评价指标,分别探究工作电流、冷却水流量和冷却水进口温度三个运行参数对燃料电池电压一致性的影响规律。仿真结果表明,工作电流对燃料电池单体电压一致性的影响程度更大,其次是冷却水进口温度,最后是冷却水流量。本研究有助于大功率燃料电池发动机的结构优化设计以及为热管理控制策略开发提供指导。

关键词：燃料电池电压一致性最大偏差率