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乌海市生态环境与经济协调发展评价

干旱区资源与环境 2017年第5期31卷 94-99页

作者：塔娜宁小莉内蒙古师范大学地理科学学院呼和浩特010020 包头师范学院资源与环境学院包头014030

以内蒙古乌海市为研究对象,采用2004-2014年的数据构建评价指标体系,基于熵值法确定权重,并运用协调发展度模型对研究区域的生态环境与经济协调发展水平进行评价与分析。结果表明:在2004-2014年间,乌海市生态环境与经济协调发展水平从... 详细信息

以内蒙古乌海市为研究对象,采用2004-2014年的数据构建评价指标体系,基于熵值法确定权重,并运用协调发展度模型对研究区域的生态环境与经济协调发展水平进行评价与分析。结果表明:在2004-2014年间,乌海市生态环境与经济协调发展水平从失调衰退型过渡到勉强协调型再到优质协调型;在此期间,经济评价指数与生态环境评价指数存在偏差,但此差值在不断下降。因此,乌海市生态环境与经济之间的发展步调趋于协调方向。

关键词：生态环境经济发展协调发展度评价乌海市

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包头市生态城市建设中社会进步指标评价

干旱区资源与环境 2014年第11期28卷 12-16页

作者：程莉宁小莉包头师范学院资源与环境学院包头014030

包头市地处我国干旱半干旱地区,生态环境比较脆弱,作为我国北方重要的资源城市和重工业城市,建设生态城市是城市未来发展的必然选择。以生态城市建设中社会生态建设作为研究对象,采用层次分析法(AHP)和专家咨询法等,从人口素质、生活质... 详细信息

包头市地处我国干旱半干旱地区,生态环境比较脆弱,作为我国北方重要的资源城市和重工业城市,建设生态城市是城市未来发展的必然选择。以生态城市建设中社会生态建设作为研究对象,采用层次分析法(AHP)和专家咨询法等,从人口素质、生活质量和城市管理三个方面构建了包头市生态城市建设社会进步三级评价指标体系,采用10/10-18/2标度确定它们的权重分别为0.163、0.300和0.537;并对包头市2012年生态城市建设中社会进步进行评价。结果表明:包头市生态城市建设中社会进步水平很低,其中人口素质水平指数0.68,生活质量指数0.78,城市管理指数0.45;存在重视基础设施建设,忽视科研投入、人才培养与引进、环境保护等方面的建设。社会生态建设应该是今后包头市生态城市建设的重要内容。

关键词：生态城市社会进步指标评价层次分析法(AHP) 包头市

Summarization and comparison of dermoscopic features on different subtypes of rosacea

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Chinese Medical Journal 2022年第12期135卷 1444-1450页

作者： Wenmin Fei Yang Han Ang Li Keke Li xiaoli ning Chengxu Li Wenju Wang Rusong Meng Yong Cui Department of Dermatology China-Japan Friendship HospitalBejing 100029China Graduate School Peking Union Medical College and Chinese Academy of Medical SciencesBejng 100730China Graduate School of Peking University Health Science Center Bejing 100191China Department of Dermatology Chengdu Second People's HospitalChengduSichuan 610017China Department of Dermatology Specialty Medical Center of the Air ForceChinese People's Liberation ArmyBeijing 100142China

Background:The dermoscopic features of rosacea have already been ***,the current findings are incomplete,and little is known about phymatous ***,this study aimed to summarize and compare the dermoscopic features and patterns of three rosacea subtypes(erythematotelangiectatic[ETR],papulopustular[PPR],and phymatous[PHR])in the Chinese Han population and to evaluate whether these features differ with patients’genders,ages,and ***:Dermoscopic images of 87 rosacea patients were collected in non-polarized and polarized dermoscopy contact modes at 20-fold *** features,including vessels,scales,follicular findings,and other structures,were summarized and ***::The reticular linear vessels and red diffuse structureless areas of ETR were *** PPR,red diffuse structureless areas,reticular linear vessels,yellow scales,follicular plugs,and follicular pustules were typical dermoscopic *** common dermoscopic features of PHR were:orange diffuse structureless areas,linear vessels with branches,perifollicular white color,orange focal structureless areas,and white *** following features statistically differed among the three rosacea subtypes:reticular linear vessels(P<0.001),unspecific linear vessels(P=0.005),linear vessels with branches(P<0.001),yellow scales(P=0.001),follicular plugs(P<0.001),perifollicular white color(P<0.001),red diffuse structureless areas(P=0.022),orange diffuse structureless areas(P<0.001),red focal structureless areas(P=0.002),orange focal structureless areas(P=0.003),white lines(P<0.001),follicular pustules(P<0.001),and black vellus hairs(P<0.001).Conclusions:The dermoscopic patterns of ETR are red diffuse structureless areas and reticular linear *** PPR,the pattern comprehends combinations of red diffuse structureless areas,reticular linear vessels,yellow scales,follicular plugs,and follicular ***,PHR is characterized by remarkable orange d

关键词： Rosacea Dermoscopic features Patterns Summarizations Comparisons

阴山北麓农牧交错区居民点空间分异特征——以包头市达尔罕茂明安联合旗为例

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干旱区资源与环境 2020年第5期34卷 78-84页

作者：张鑫宁小莉佟宝全内蒙古师范大学地理科学学院呼和浩特010022 包头师范学院资源与环境学院包头014030

探究农牧交错区居民点的空间分异特征,对于农牧交错区的居民点调整、重构与发展和生态环境修复与可持续发展具有重要意义。运用最近邻指数法、核密度估计法、全局聚类检验、空间"热点"探测、Voronoi图Cv值和实地考察等方法,深入分析阴... 详细信息

探究农牧交错区居民点的空间分异特征,对于农牧交错区的居民点调整、重构与发展和生态环境修复与可持续发展具有重要意义。运用最近邻指数法、核密度估计法、全局聚类检验、空间"热点"探测、Voronoi图Cv值和实地考察等方法,深入分析阴山北麓农牧交错区居民点的空间分异特征。结果表明:2016年,达茂旗居民点分布整体较为聚集,呈"东南密西北疏"的空间差异,研究区居民点斑块规模相差悬殊,小型居民点占主体;区域上,居民点分布格局呈现出明显的区域差异性,"冷热点"分异明显,呈现局部集中趋势;在乡镇尺度上,石宝镇空间分布类型属于随机分布,其它几个乡镇的空间分布属于集群分布;农业生产区居民点规模分布大而密集,牧业生产区居民点规模分布呈现小而零散的分布特点。总体上,分析该农牧交错区的空间分异特征,可对整个农牧交错区居民点空间布局调整、优化提供重要的借鉴价值。

关键词：农牧交错区居民点空间分异达茂旗

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包头市经济发展水平预测分析

干旱区资源与环境 2016年第2期30卷 45-50页

作者：宁小莉于佳生包头师范学院资源与环境学院包头014030 内蒙古科技大学经济与管理学院包头014010

城市经济的发展水平不仅体现在经济增长速度的提升,还体现在经济规模、结构、质量和效益的统筹兼顾。如何因地制宜地进行经济评价,并对其发展趋势进行科学合理地预测,是经济建设亟待解决的一项重大课题。文中在建立经济发展指标体系的... 详细信息

城市经济的发展水平不仅体现在经济增长速度的提升,还体现在经济规模、结构、质量和效益的统筹兼顾。如何因地制宜地进行经济评价,并对其发展趋势进行科学合理地预测,是经济建设亟待解决的一项重大课题。文中在建立经济发展指标体系的基础上,采用GM(1,1)模型,对2014-2020年包头市城市建设中的各项经济指标以及经济发展总体水平进行预测。结果表明,在没有其他因素变化的情况下,除"第三产业占GDP比重"外,其它各项指标均朝着良好的方向发展。但收入性指标增长落后于GDP增幅、经济结构失衡、经济发展方式粗放依然是制约未来包头市经济发展的主要因素。同时,GM(1,1)模型能够很好地拟合经济发展状况,适合预测经济发展的各项指标,预测结果良好。

关键词：经济发展指标体系 GM(1,1)模型包头市

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不确定需求下带有数量折扣的零售商定购策略

物流技术 2014年第6期33卷 192-194页

作者：宁晓利南阳师范学院经济与管理学院河南南阳473061

针对需求无法预知的情形,假设需求速度在一定范围内波动,从在线理论和竞争分析的角度出发,为零售商设计在线意义下的订购策略Aon,并证明了零售商采用此策略时的成本接近顾客需求确定时的最小成本,最多不超过其常数倍。最后通过算例分析... 详细信息

针对需求无法预知的情形,假设需求速度在一定范围内波动,从在线理论和竞争分析的角度出发,为零售商设计在线意义下的订购策略Aon,并证明了零售商采用此策略时的成本接近顾客需求确定时的最小成本,最多不超过其常数倍。最后通过算例分析验证了这一结论,为零售商的运营提供指导性建议。

关键词：数量折扣在线策略离线最优策略订购批量

Construction of a 12-metal Zn(Ⅱ)-Nd(Ⅲ) nanocluster for ratiometric fluorescence detection of inflammatory marker neopterin

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Journal of Rare Earths 2025年第2期43卷 270-275页

作者： Huanyin Yu Xiaoping Yang xiaoli Lv Xianfeng Huang College of Chemistry and Materials Engineering Wenzhou UniversityZhejiang Key Laboratory of Carbon MaterialsKey Lab of Biohealth Materials and Chemistry of Wenzhou

A 12-metal Zn（Ⅱ）-Nd（Ⅲ） cluster 1（sizes:1.8 nm×2.0 nm×2.0 nm） was synthesized from a long-chain type Schiff base *** displays ratiometric fluorescence response to neopterin（Neo） with high selectivity and sensitivity,which can be expressed by the equation I545nm/I1060nm=A·[Neo]2+B·[Neo]+C.1 is used to quantitatively test Neo concentrations in fetal calf serum（FCS） and urine,and the recovery ranges are 98.57%-103.82% and 99.25%-103.50%,respectively,while the relative standard deviations（RSDs） are 7.89%-9.46% and 1.85%-4.16%,*** limits of detection of 1 to Neo in FCS and urine are 0.034 and 0.021 μmol/L,respectively.

关键词： Neopterin NIR luminescence Rare earths Ratiometric fluorescence detection Zn(II)-Nd(III) nanocluster

Deficiency of two-pore segment channel 2 contributes to systemic lupus erythematosus via regulation of apoptosis and cell cycle

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Chinese Medical Journal 2022年第4期135卷 447-455页

作者： Keke Li Jingkai Xu Ke Xue Ruixing Yu Chengxu Li Wenmin Fei xiaoli ning Yang Han Ziyi Wang Jun Shu Yong Cui Department of Dermatology China-Japan Friendship HospitalBeijing 100029China Graduate School of Peking Union Medical College Chinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100730China Institute of Clinical Medical Science China-Japan Friendship HospitalBeijing 100029China

Background:Systemic lupus erythematosus(SLE)is a complex autoimmune disease,and the mechanism of SLE is yet to be fully *** aim of this study was to explore the role of two-pore segment channel 2(TPCN2)in SLE ***:Quantitative reverse transcription polymerase chain reaction(qRT-PCR)was used to detect the expression ofTPCN2 in *** performed a loss-of-function assay by lentiviral construct in Jurkat and THP-1 *** ofTPCN2 were confirmed at the RNA level by qRT-PCR and protein level by Western *** Count Kit-8 and flow cytometry were used to analyze the cell proliferation,apoptosis,and cell cycle ofTPCN2-deficient *** addition,gene expression profile ofTPCN2-deficient cells was analyzed by RNA sequencing(RNA-seq).Results:TPCN2 knockdown with short hairpin RNA(shRNA)-mediated lentiviruses inhibited cell proliferation,and induced apoptosis and cell-cycle arrest of G2/M phase in both Jurkat and THP-1 *** analyzed the transcriptome of knockdown-TPCN2-Jurkat cells,and screened the differential genes,which were enriched for the G2/M checkpoint,complement,and interleukin-6-Janus kinase-signal transducer and activator of transcription pathways,as well as changes in levels of forkhead box O,phosphatidylinositol 3-kinase/protein kinase B/mechanistic target of rapamycin,and T cell receptor pathways;moreover,TPCN2 significantly influenced cellular processes and biological ***:TPCN2 might be a potential protective factor against SLE.

关键词： TPCN2 Systemic lupus erythematosus RNA sequencing analysis Apoptosis Cell cycle

Asking one mechanism in glial cells during neuroinflammation

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Neural Regeneration Research 2025年第4期20卷 1077-1078页

作者： xiaoli Guo Chikako Harada Takayuki Harada Visual Research Project Tokyo Metropolitan Institute of Medical ScienceTokyoJapan

Multiple sclerosis(MS),which is characterized by inflammatory demyelination in the central nervous system(CNS),is the most common neurological disease in the young adult *** autoimmune encephalomyelitis(EAE),an animal model of MS,is often used in preclinical *** data indicate that in addition to immune cells such as T cells and dendritic cells,CNS resident microglia and astrocytes play important roles in demyelinating neuroinflammation(Healy et al.,2022).In particular,microglia are key immune-competent cells that can respond to environmental *** depletion of transforming growth factor-β-activated kinase 1,a mitogen-associated protein kinase kinase kinase,in microglia is reported to reduce CNS inflammation and diminish axonal and myelin damage *** suggests that elucidating the mechanisms of microglia-specific responses during pathologies may help in the development of treatments that reduce EAE/MS disease severity(Goldmann et al.,2013).

关键词： inflammation clinical