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Effect of Online Social Networking on Emotional Status and Its Interaction with Offline Reality during the Early Stage of the COVID-19 Pandemic in China

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International Journal of Mental Health Promotion 2023年第9期25卷 1041-1052页

作者： Xiaolin Lu xiaolei miao Department of Physical Education Xidian UniversityXi’an710126China Department of Sociology Xi’an Jiaotong UniversityXi’an710049China

Background:During the early stages of the COVID-19 pandemic in China,social interactions shifted to online spaces due to lockdowns and social distancing measures.As a result,the impact of online social networking on users’emotional status has become stronger than ever.This study examines the association between online social networking and Internet users’emotional status and how offline reality affects this relationship.Methods:The study utilizes cross-sectional online survey data(n=3004)and Baidu Migration big data from the first 3 months of the pandemic.Two dimensions of online networking are measured:social support and information sources.Results:First,individuals’online social support(β=0.16,p<0.05)and information sources(β=0.08,p<0.01)are both positively associated to their emotional status during the epidemic.Second,these positive associations are moderated by social status and provincial pandemic control interventions.With regards to the moderation effect of social status,the constructive impact of information sources on emotional well-being is more pronounced among individuals from vulnerable groups compared to those who are not.With regard to the moderation effect of provincial interventions,online social support has the potential to alleviate the adverse repercussions of high rates of confirmed COVID-19 cases and strict lockdown measures while simultaneously augmenting the favorable effects of recovery.Conclusion:The various dimensions of social networking exert distinct effects on emotional status through diverse mechanisms,all of which must be taken into account when designing and adapting pandemic-control interventions.

关键词： COVID-19 emotional status online social networking social support information sources

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Honokiol attenuates acetaminophen-induced acute liver injury by inhibiting hepatic CYP1A2 activity and improving liver mitochondrial dysfunction

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Chinese Herbal Medicines 2023年第2期15卷 231-239页

作者： xiaolei miao Chengting Jin Jiao Liu Junjun Wang Yong Chen Hubei Key Laboratory of Biotechnology of Chinese Traditional Medicine National&Local Joint Engineering Research Center of High-throughput Drug Screening TechnologyHubei UniversityWuhan 430062China School of Pharmacy Hubei University of Science and TechnologyXianning 437100China

Objective:Acetaminophen(APAP)overdose is a common cause of liver injury.This study aimed to investigate the protective effect of honokiol(Hon)against APAP-induced hepatotoxicity and its potential mechanism.Methods:C57BL/6 mice were administrated with Hon(10 and 30 mg/kg)after APAP(300 mg/kg)treatment.On 1.5 h and 5 h after Hon treatment,mice were sacrificed.Serum and liver were collected.And then,liver injury-related indexes,APAP metabolism-related indexes,mitochondrial respiratory chain function-related indexes,and mitochondrial membrane function-related protein expression were evaluated.Results:It was found that Hon significantly decreased serum alanine aminotransferase(ALT)/aspartate aminotransferase(AST)activity and glutathione(GSH)depletion,increased hepatic catalase(CAT)and GSH peroxidase(GSH-Px)activities,reduced hepatic MDA and 3-nitrotyrosine contents,inhibited hepatic CYP1A2 activity and APAP protein adducts(APAP-CYS)formation.Meanwhile,oxidative phosphorylation capacity of complex I and electron transfer capacity of complex IV in mitochondrial respiratory chain was increased,whereas the release of H2O2 in the mitochondria was decreased following Hon treatment.Furthermore,Hon markedly down-regulated p-JNK in both cytosol and mitochondria,and obviously inhibited the release of apoptosis inducing factor(AIF)and endonuclease G(EndoG)from mitochondria to cytosol.Conclusion:Hon alleviated APAP-induced liver injury through the following pathways:Reducing the production of APAP-CYS by inhibiting CYP1A2 activity;Ameliorating hepatic oxidative stress by increasing the levels of hepatic CAT,GSH-Px and GSH;Improving mitochondrial respiratory chain function by promoting oxidative phosphorylation capacity of complex I and electron transfer capacity of complex IV;Improving the function of mitochondrial membrane by inhibiting p-JNK and its translocation to mitochondria,thereby reducing the release of AIF and EndoG.

关键词： acetaminophen CYP1A2 honokiol liver mitochondrial dysfunction Magnolia officinalis Rehd.et Wils. oxidant stress

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中国居民体育锻炼城乡差异的内在机制与变化趋势(2010—2021)

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北京体育大学学报 2024年第3期47卷 70-84页

作者：鲁肖麟缪晓雷西安电子科技大学体育部陕西西安710126 西安交通大学人文学院社会学系陕西西安710049

我国居民体育锻炼的城乡差异持续存在、不可忽视。体育参与的城乡融合发展是建设体育强国的必由之路,也是高质量发展的应有之义。研究聚焦中国特色社会主义新时代十余年来的城乡体育锻炼,使用中国综合社会调查(CGSS2010-2021)合并数据,... 详细信息

我国居民体育锻炼的城乡差异持续存在、不可忽视。体育参与的城乡融合发展是建设体育强国的必由之路,也是高质量发展的应有之义。研究聚焦中国特色社会主义新时代十余年来的城乡体育锻炼,使用中国综合社会调查(CGSS2010-2021)合并数据,运用多元线性回归、边际效应分析、倾向值匹配等量化方法分析我国居民体育锻炼频率的城乡差异与变迁趋势,比较经济地位、文化资本、社会资本和数字赋能4种机制对城乡居民体育锻炼频率的作用及其演变,分析发现:1)十余年间我国居民体育锻炼频率整体上显著提升,但仍然存在城乡差异。2)在控制个体因素后,体育锻炼频率的城乡净差异持续缩小。3)4种机制对体育锻炼的作用显著且存在城乡差异。对于农村居民,社会资本和文化资本的体育锻炼促进作用不断增强,数字赋能作用减弱;对于城市居民,社会资本的作用减弱而数字赋能的作用增强。研究结果既证明了全民健身和乡村振兴等相关政策举措成效显著,也要求在未来的政策实践中更加关注城乡社会背景与体育文化差异,增强农村体育锻炼促进措施的针对性,以实现覆盖城乡、全民共享的中国式现代化体育强国。

关键词：体育锻炼城乡差异变迁趋势机制比较

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基于SPOC的翻转课堂教学方法在麻醉科住院医师神经阻滞教学中的应用

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中国高等医学教育 2024年第1期 74-76页

作者：苗晓蕾穆博然魏昌伟首都医科大学附属北京朝阳医院首都医科大学附属北京朝阳医院教育处北京100020

目的:探讨基于SPOC的翻转课堂教学方法在麻醉科住院医师神经阻滞教学中的应用效果。方法:选取2021年1月至2021年3月在麻醉科规范化培训的38名住院医师为研究对象,随机分为试验组(n=19)和对照组(n=19)。试验组采用基于SPOC的翻转课堂教... 详细信息

目的:探讨基于SPOC的翻转课堂教学方法在麻醉科住院医师神经阻滞教学中的应用效果。方法:选取2021年1月至2021年3月在麻醉科规范化培训的38名住院医师为研究对象,随机分为试验组(n=19)和对照组(n=19)。试验组采用基于SPOC的翻转课堂教学方法,对照组采用传统教学方法。结果:试验组学生理论考核成绩明显优于对照组(P0.05)。问卷调查结果显示,这种教学方法获得了试验组学生的广泛认可。结论:在麻醉科规范化培训住院医师神经阻滞教学中,采用基于SPOC的翻转课堂教学方法取得了良好的教学效果。

关键词： SPOC 翻转课堂麻醉学神经阻滞

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基于熵权TOPSIS模型对白芨多糖脱蛋白体系的评价研究

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食品工业科技 2024年第7期45卷 76-85页

作者：袁高阳秦心睿聂晓兵金文芳杨玉玉刘诗菡范宝磊苗潇磊湖北科技学院药学院湖北咸宁437100 辐射化学与功能材料湖北省重点实验室湖北咸宁437100 湖北省智慧康养产业研究院湖北咸宁437100

利用熵权TOPSIS模型对比Sevage法、乙腈法和三氯乙酸(TCA)法脱除粗白芨多糖(BSP)蛋白的效果,探究熵权TOPSIS用于BSP脱蛋白体系评价的合理性。以BSP保留率和蛋白质脱除率综合评分,筛选出最佳处理条件;构建出包括单糖组分、氧化自由基清... 详细信息

利用熵权TOPSIS模型对比Sevage法、乙腈法和三氯乙酸(TCA)法脱除粗白芨多糖(BSP)蛋白的效果,探究熵权TOPSIS用于BSP脱蛋白体系评价的合理性。以BSP保留率和蛋白质脱除率综合评分,筛选出最佳处理条件;构建出包括单糖组分、氧化自由基清除能力(ORAC)、DPPH自由基半数清除浓度(IC_(50))在内的9个具体评价指标的白芨多糖脱蛋白评价体系,以紫外分光光度计和傅里叶变换红外光谱仪扫描为辅,以熵权TOPSIS对三种白芨多糖除蛋白方案的结果进行评价。经过综合评分,Sevage法最佳萃取次数为1次,此时的蛋白质脱除率为22.9%,多糖保留率为99.11%;乙腈法最佳质量浓度为60%,蛋白质脱除率为89.11%,多糖保留率为97.36%;TCA法最佳质量浓度为10%,蛋白质脱除率为70.64%,多糖保留率为70.03%;对比同浓度下三种多糖的ORAC值和IC_(50)发现,乙腈法处理的多糖ORAC值高于阳性对照组(P<0.05),Sevage法处理后的多糖具有最强的抗氧化活性;白芨多糖脱蛋白评价体系经熵权TOPSIS模型分析结果表明Sevage法脱蛋白效果最优与预期结果相符。研究结果表明熵权TOPSIS模型可用于白芨多糖脱蛋白体系评价。

关键词：白芨多糖体外抗氧化活性白芨多糖脱蛋白评价体系熵权TOPSIS模型

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互联共信:数字时代的线上社会资本与普遍信任

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开放时代 2023年第6期 102-116,M0006页

作者：缪晓雷西安交通大学社会学系

普遍信任体现了对社会一般个体的认同倾向,能够反映出对社会整体的信心与信念。普遍信任的影响因素和提升机制是实现社会高质量发展的重要议题。在数字时代,互联网实现了人际关系的“互联”,本文关注互联网使用能否进一步带来社会的“... 详细信息

普遍信任体现了对社会一般个体的认同倾向,能够反映出对社会整体的信心与信念。普遍信任的影响因素和提升机制是实现社会高质量发展的重要议题。在数字时代,互联网实现了人际关系的“互联”,本文关注互联网使用能否进一步带来社会的“共信”,即互联网使用能否提升社会普遍信任水平。基于社会资本因素论,本研究认为数字社会的线上社会资本通过认同逻辑和认知逻辑提升社会普遍信任,通过使用2021年的社会网络与职业经历调查数据进行实证研究发现:线上社会资本的内聚型和外联型两个维度都可以提升普遍信任;存在互联网使用提升线上社会资本,进而提升普遍信任的积极路径;互联网休闲娱乐使用会降低普遍信任,但与外联型线上社会资本存在交互作用,可以通过外联型线上社会资本的提升来弥补对普遍信任的负向影响。

关键词：线上社会资本内聚型外联型普遍信任

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Advancing electrochemical drilling process via coupling of flow field and electric field in pulsating state generated by a novel tube tool

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Chinese Journal of Aeronautics 2024年第4期37卷 542-555页

作者： Liang CHENG xiaolei CHEN Zhisen YE Yongjun ZHANG State Key Laboratory of Precision Electronic Manufacturing Technology and Equipment Guangdong University of TechnologyGuangzhou 510006China Guangdong Key Laboratory of Advanced Manufacturing Technology of Marine Energy Equipment Guangdong University of TechnologyGuangzhou 510006China Guangzhou Key Laboratory of Nontraditional Machining and Equipment Guangdong University of TechnologyGuangzhou 510006China

This paper introduces an improvement to electrochemical drilling process by coupling flow field and electric field in pulsating state. A novel tube with half-wedged shape at the end(HW-tube) is prepared, with both sidewall and wedged part of the HW-tube insulated. Only the flat part is utilized to provide electric field for electrochemical drilling. By rotating the HW-tube, both flow field and electric field in pulsating state are generated, alternating in different positions within the inter-electrode gap(IEG). The pulsating flow field enhances the mass transfer process, while pulsating electric field disperses material dissolution process and distribution of electrolytic byproducts. Both pulsating fields are coupled at the same frequency, further enhancing the electrochemical drilling process. Simulation results indicate that both flow field and electric field in pulsating state are generated. Compared to the traditional tube, the HW-tube significantly reduces the number of residual particles in IEG, and this number is further reduced by increasing the rotation speed. Experimental results reveal that the surface quality and dimensional uniformity of small hole are improved with HW-tube. With feed rate of 2.22 mm/min, a small hole with diameter of 1.52± 0.017 mm is drilled, resulting in a surface roughness of 0.331 μm.

关键词： Small holes Electrochemical drilling Tools Pulsating flow field Pulsating electric field

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Parallelization strategies for resolved simulations of fluid-structure-particle interactions

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Applied Mathematics and Mechanics(English Edition) 2024年第5期45卷 857-872页

作者： Jianhua QIN Fei LIAO Guodan DONG xiaolei YANG The State Key Laboratory of Nonlinear Mechanics Institute of MechanicsChinese Academy of SciencesBeijing 100190China Interdisciplinary Center for Fundamental and Frontier Sciences Nanjing University of Science and TechnologyJiangyin 214443Jiangsu ProvinceChina School of Aeronautics Northwestern Polytechnical UniversityXi'an 710072China School of Engineering Sciences University of Chinese Academy of SciencesBeijing 100049China

Fluid-structure-particle interactions in three spatial dimensions happen in many environmental and engineering flows.This paper presents the parallel algorithms for the hybrid diffuse and sharp interface immersed boundary(IB)method developed in our previous work.For the moving structure modeled using the sharp interface IB method,a recursive box method is developed for efficiently classifying the background grid nodes.For the particles modeled using the diffuse interface IB method,a‘master-slave’approach is adopted.For the particle-particle interaction(PPI)and particle-structure interaction(PSI),a fast algorithm for classifying the active and inactive Lagrangian points,which discretize the particle surface,is developed for the‘dry’contact approach.The results show that the proposed recursive box method can reduce the classifying time from 52seconds to 0.3 seconds.Acceptable parallel efficiency is obtained for cases with different particle concentrations.Furthermore,the lubrication model is utilized when a particle approaches a wall,enabling an accurate simulation of the rebounding phenomena in the benchmark particle-wall collision problem.At last,the capability of the proposed computational framework is demonstrated by simulating particle-laden turbulent channel flows with rough walls.

关键词： particle-resolved direct numerical simulation particle-laden flow complex geometry resolved fluid-structure-particle interaction(RFSPI) immersed boundary(IB)method

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Multiple exciton generation effect in photocatalytic overall water splitting

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Science China Chemistry 2024年第2期67卷 424-425页

作者： xiaolei Guo Ji-Jun Zou Key Laboratory for Green Chemical Technology of Ministry of Education School of Chemical Engineering and TechnologyTianjin UniversityTianjin300072China

This highlight is based on recent research published in Nature Energy by Li and co-workers [1] from Northwestern Polytechnology University, reporting an exceeding 100% internal quantum efficiency(IQE) in photocatalytic overall water splitting. This breakthrough promises a bright future for efficient photocatalyst design by utilizing the multiple exciton effect(MEG).

关键词： splitting effect utilizing

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Game-changing insights on vertebral skeletal stem cells in bone metastasis and therapeutic horizons

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Oncology Research 2024年第1期32卷 95-98页

作者： QIUQIANG CHEN xiaolei ZHAO WENXUE MA Key Laboratory for Translational Medicine The First Affiliated HospitalHuzhou University School of MedicineHuzhou313000China Department of Urology Huaihe Hospital of Henan UniversityKaifeng475004China Department of Medicine Moores Cancer CenterSanford Stem Cell InstituteUniversity of California San DiegoLa Jolla92093USA

Greenblatt and his team have unveiled vertebral skeletal stem cells(vSSCs)as a critical player in the landscape of bone metastasis.This commentary delves into the transformative discoveries surrounding vSSCs,emphasizing their distinct role in bone metastasis compared to other stem cell lineages.We illuminate the unique properties and functions of vSSCs,which may account for the elevated susceptibility of vertebral bones to metastatic invasion.Furthermore,we explore the exciting therapeutic horizons opened by this newfound understanding.These include potential interventions targeting vSSCs,modulation of associated signaling pathways,and broader implications for the treatment and management of bone metastasis.By shedding light on these game-changing insights,we hope to pave the way for novel strategies that could revolutionize the prognosis and treatment landscape for cancer patients with metastatic bone disease.

关键词： Vertebral skeletal stem cells(vSSCs) Stem cell research Metastasis Breast prostate and lung cancers Spinal metastasis Matthew Greenblatt Genetic expressions

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