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Chinese social media reaction to the MERS-CoV and avian influenza A(H7N9) outbreaks

Infectious Diseases of Poverty 2013年第1期2卷 259-269,258页

作者： Isaac Chun-Hai Fung King-wa Fu Yuchen Ying Braydon Schaible Yi Hao Chung-Hong Chan Zion Tsz-Ho Tse Department of Epidemiology Jiann-Ping Hsu College of Public HealthGeorgia Southern UniversityStatesboroGeorgiaUSA Journalism and Media Studies Center The University of Hong KongHong Kong Special Administrative RegionChina Department of Computer Science The University of GeorgiaAthensGeorgiaUSA Department of Biostatistics Jiann-Ping Hsu College of Public HealthGeorgia Southern UniversityStatesboroGeorgiaUSA College of Engineering The University of GeorgiaAthensGeorgiaUSA

Background:As internet and social media use have skyrocketed,epidemiologists have begun to use online data such as google query data and Twitter trends to track the activity levels of influenza and other infectious *** China,Weibo is an extremely popular microblogging site that is equivalent to *** on the wealth of public opinion data contained in posts on Weibo,this study used Weibo as a measure of the Chinese people’s reactions to two different outbreaks:the 2012 Middle East Respiratory Syndrome Coronavirus(MERS-CoV)outbreak,and the 2013 outbreak of human infection of avian influenza A(H7N9)in ***:Keyword searches were performed in Weibo data collected by The University of Hong Kong’s Weiboscope *** values were determined for each keyword and reaction values per million posts in the days after outbreak information was released to the ***:The results show that the Chinese people reacted significantly to both outbreaks online,where their social media reaction was two orders of magnitude stronger to the H7N9 influenza outbreak that happened in China than the MERS-CoV outbreak that was far away from ***:These results demonstrate that social media could be a useful measure of public awareness and reaction to disease outbreak information released by health authorities.

关键词： H7N9 logging Middle

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无线传感器网络分布式同步协议

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西安电子科技大学学报 2016年第4期43卷 105-110,134页

作者：王晶张帅高丹王营冠中国科学院上海微系统与信息技术研究所无线传感网与通信重点实验室上海201899

针对无线传感器网络同步问题,提出分布式时间同步和分布式数据同步的解决方法.前者要求簇头网络进行局部信息交互,并采用低通滤波技术去除噪声干扰;后者为节点提供网络数据均值,要求簇头网络执行比例一致性算法,簇头在迭代过程中引入簇... 详细信息

针对无线传感器网络同步问题,提出分布式时间同步和分布式数据同步的解决方法.前者要求簇头网络进行局部信息交互,并采用低通滤波技术去除噪声干扰;后者为节点提供网络数据均值,要求簇头网络执行比例一致性算法,簇头在迭代过程中引入簇内节点数量.实验结果表明,分布式时间同步具备抗噪声能力,该算法在前期收敛速度最快.网格状网络和随机网络实验表明,分布式时间同步和分布式数据同步的通信开销非常低,它们的收敛速度均高于普通数据同步.

关键词：无线传感器网络同步分簇通信开销收敛速度

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Synthesis, Crystal Structure and Characterization of a New Manganese(Ⅱ) Tetracarboxylate

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Chinese Journal of Structural Chemistry 2008年第2期27卷 167-170页

作者： YINg Shao-Ming FANg Xiao-Niu ZHANg Ding-wa CHEN Wen-Tong LIU Jiu-Hui Department of Chemistry Jinggangshan College Ji＇an Jiangxi 343009 China

By hydrothermal synthesis, a manganese（H） tetracarboxylate [Mn（2,2′-bipyridi- ne）（btec）0.5（HEO）]En （H4btec = 1,2,4,5-benzenetetracarboxylic acid） was obtained and characterized by single-crystal X-ray diffraction, IR, elemental analysis and thermogravimetric analysis. It crystallizes in triclinic, space group P1, with a = 7.721（4）, b = 8.905（5）, c = 10.712（6）A, a = 80.899（8）, β = 70.371（8）, y = 78.201（8）°, Z = 2, V= 675.8（7）A3, Mr= 354.20, De= 1.741 g/cm^3,μ = 1.007 mm^-1, F（000） = 360, S = 0.956, （△/σ）max = 0.000, the final R = 0.0490 and wR = 0.1262. This compound presents an infinite 1D polymer featuring a double-chain structure. The Mn（Ⅱ） ion is five-coordinated. The four carboxylate groups of btec4- are all deprotonated and coordinated to four Mn atoms in a monodentate fashion, forming a 1D double chain structure with a cavity. Such chains are interconnected by π-π stacking interactions into 2D layers which are further interlinked into a supramolecular structure by hydrogen bonds.

关键词： hydrothermal synthesis tetracarboxylate crystal structure double chain

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Supramolecular Manipulation of Intracellular Acidic Vesicles to Improve Cellular Self-Repair and Self-Defense

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CCS Chemistry 2024年第6期6卷 1487-1498页

作者： Ziyi wa.g Chen Sun Yu Dong Yuan-Fu Ding Chen Zhao Ian wa Ho Jiahong Lu Ruibing wa.g State Key Laboratory of Quality Research in Chinese Medicine Institute of Chinese Medical SciencesUniversity of MacaoTaipaMacao 999078China

Lysosomes are the“cell stomach”that digests various species including macromolecules and pathogens for self-repair and self-defense upon fusion with endosomes,autophagosomes,and ***,artificially manipulating intracellular vesicles could potentially promote lysosome-mediated intracellular digestion for disease prevention and ***,a supramolecular strategy to efficiently tether and fuse acidic vesicles(i.e.,lysosomes,late endosomes,autolysosomes,and phagosomes)has been developed for the first time to enhance the digestion of cellular wastes and foreign matter,including pathogens.A linear polyethylene glycol(PEg)derivative dually tagged with morpholine(MOR)and adamantane(ADA)on the opposite side,namely,MOR-PEg-ADA,was designed to target intracellular acidic vesicles via MOR and to decorate their surfaces with ***,the addition of cucurbit[7]uril(CB[7])grafted hyaluronic acid(HA)induced supramolecular tethering and fusion of acidic vesicles via strong host-guest interactions between CB[7]of CB[7]-HA and ADA residing on the surface of acidic *** a proof-ofconcept,the overall cellular metabolism,including endogenous autophagy and the exogenous endocytosis and phagocytosis,was effectively upregulated,demonstrating that supramolecular regulation of the dynamics of intracellular acidic vesicles may promote the lysosome’s digestion to significantly improve cellular self-repair and self-defense.

关键词： supramolecular chemistry organelle regulation intracellular acidic vesicles lysosomes selfdefense self-repair

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Two Innovative Techniques to Study the Environmental Impacts of Urban Forms

Two Innovative Techniques to Study the Environmental Impacts...

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第四届粤港澳可持续发展研讨会

作者： U wa TANg Department of Civil and Environmental Engineering University of Macau

This paper introduces two innovative techniques,i.e.,the vehicle-following measuring technique and the high-spatial resolution air/noise modeling technique,that have been used recently to study of urban environment in the Macao *** related interna- tional conference papers have been awarded as one of the best student papers in the annual din- ner of the Hong Kong Society for Transportation Studies in 2007 and the annual dinner of the International Association of Chinese Professionals in geographic Information Sciences in 2008. By using the vehicle-following measuring technique,vehicle gaseous emissions(NO, CO,CO and HC)and driver’s particle exposures(PM1,PM2.5,and PM10)have been measured during heavy traffic congestion in urban *** with the traditional la- boratory tests,the vehicle-following measurement technique can obtain a wide variety of vehi- cle emission data on the road as cooperation from the vehicle’s owners is no longer necessary. By using the high-spatial resolution modeling technique,traffic-induced air and noise pollu- tions in front of individual building facades on both sides of the road can be *** two innovative techniques have the capability to provide city decision-makers with a different perspective on vehicle transport and urban form that both impact air quality and noise.

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Cutaneous Metastases Arising from Synovial Sarcoma： A Case Report

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Chinese Medical Journal 2017年第24期130卷 3019-3020页

作者： Xue Zeng Li Li wa-Li Liu Department of Dermatology Guang'anmen Hospital China Academy of Chinese Medical Sciences Beijing 100053 China Department of Dermatopathology Guang'anmen Hospital China Academy of Chinese Medical Sciences Beijing 100053 China

To the Editor：Synovial sarcoma （SS） is a relatively rare type of soft tissue sarcoma that constitutes approximately 8% of all soft tissue *** frequently occurs in the para-articular structures of the limbs and is predominantly found in the lower *** other involved locations of invasion are lung,lymph nodes,and ***,the skin is rarely involved.[1-3] Here,we reported an extremely rare case ofbiphasic SS presenting with disseminated cutaneous metastases.

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免疫毒素和中枢神经系统肿瘤

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国外医学（肿瘤学分册） 1993年第1期20卷 33-34页

作者： Hall wa 秦力

本文综述了免疫毒素治疗中枢神经系统肿瘤的基本原理、体内外实验的研究进展,以及临床应用的初步效果,并介绍了免疫毒素的毒副反应及其防治方法.

关键词：中枢神经系统肿瘤免疫毒素

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Challenges and opportunities in the production of magnesium parts by directed energy deposition processes

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Journal of Magnesium and Alloys 2024年第5期12卷 1663-1686页

作者： gürel Cam Ali günen Iskenderun Technical University Faculty of Engineering and Natural SciencesDepartment of Mechanical Engineering31200 Iskenderun-HatayTurkey Iskenderun Technical University Faculty of Engineering and Natural SciencesDepartment of Metallurgy and Materials Engineering31200 Iskenderun-HatayTurkey

Mg-alloys have gained considerable attention in recent years for their outstanding properties such as lightweight,high specific strength,and corrosion resistance,making them attractive for applications in medical,aerospace,automotive,and other transport ***,their widespread application is hindered by their low formability at room temperature due to limited slip *** Mg-alloys have low mechanical properties due to the presence of casting defects such as porosity and anisotropy in addition to the high *** casting methods benefit from established process optimization techniques for these problems,additive manufacturing methods are increasingly replacing casting methods in Mg alloys as they provide more precise control over the microstructure and allow specific grain orientations,potentially enabling easier optimization of anisotropy properties in certain *** metal additive manufacturing(MAM)technology also results in some manufacturing defects such as inhomogeneous microstructural evolution and porosity and additively manufactured Mg alloy parts exhibit lower properties than the wrought parts,they in general exhibit superior properties than the cast ***,MAM is a promising technique to produce Mg alloy *** energy deposition processes,particularly wire arc directed energy deposition(wa-DED),have emerged as an advantageous additive manufacturing(AM)technique for metallic materials including magnesium alloys,offering advantages such as high deposition rates,improved material efficiency,and reduced production costs compared to subtractive ***,the inherent challenges associated with magnesium,such as its high reactivity and susceptibility to oxidation,pose unique hurdles in the application of this *** review paper delves into the progress made in the application of DED technology to Mg-alloys,its challenges,and ***,the predominant imperfections,notably inhomo

关键词： Additive manufacturing DED processes Arc-DED Wire arc additive manufacturing(waAM) 3-D printing High deposition rate

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Protective effects of a polymethoxy flavonoids-rich Citrus aurantium peel extract on liver fibrosis induced by bile duct ligation in mice

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Asian Pacific Journal of Tropical Medicine 2016年第12期9卷 1135-1141页

作者： Seol-wa Lim Dong-Ryung Lee Bong-Keun Choi Hong-Suk Kim Seung Hwan Yang Joo-Won Suh Kyung Soo Kim graduate School of Biomedicine & Health Sciences Catholic University Nutra Pharm Tech Interdisciplinary Program of Biomodulation Myongji University Department of Biotechnology Chonnam National University Center for Nutraceutical and Pharmaceutical Materials Myongji University

Objective: To evaluate the possible protective effect of Citrus aurantium peel extract(CAE) against apoptosis in cholestatic liver fibrosis induced by bile duct ligation in mice. Methods: Male ICR mice were divided to 5 groups: 1) Control group(Sham-operated mice), 2) Cholestatic liver injury group induced by bile duct ligation(BDL), 3) BDL mice treated with silymarin(200 mg/kg) for 4 weeks, 4) BDL mice treated with 50 mg/kg CAE for 4 weeks, 5) BDL mice treated with 200 mg/kg CAE for 4 weeks. Mice were sacrificed and liver fibrosis was evaluated by serum and hepatic tissue biochemistry tests and liver histopathological examination. Effects of CAE on inflammation and apoptosis gene regulation were investigated through real-time PCR. CAE effect on lipid metabolism related signaling was determined by western blot analysis. Results: In BDL mice, administration of CAE for 4 weeks markedly attenuated liver fibrosis based on histopathological alteration. Serum and hepatic tissue biochemistry results revealed that CAE(50 and 200 mg/kg) decreased the levels of alanine transaminase, aspartate transaminase, gamma glutamyl transferase, total bilirubin, nitric oxide, and thiobarbituric acid reactive substances. Real-time PCR and western blot analysis showed that CAE regulated inflammation, apoptosis, and lipid metabolism factors increased by BDL. Interleukin family, tumor necrosis factor α, and related apoptosis factors m RNA levels were increased by BDL treatment. However, these increases were suppressed by CAE administration. In addition, CAE effectively increased phosphorylation of AMPactivated protein kinase, nuclear factor E2-related factor 2, and related cytoprotective proteins. Conclusions: CAE can efficiently regulate BDL-induced liver injury with antioxidant, antiinflammatory, and antiapoptotic activities.

关键词： Liver injury Bile duct ligation Cholestasis Citrus aurantium peel extract Hepatic fibrosis

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针对α网的最优线性约束转换方法

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西安电子科技大学学报 2015年第5期42卷 183-187,212页

作者：张丽赵良煦王寿光汪成英浙江工商大学信息与电子工程学院浙江杭州310018

针对不可控影响子网为α网的一类Petri网,提出了将给定的广义互斥约束转换成最优允许线性约束的方法.该方法首先获得了该网的不可控影响子网;其次,提出了转换后的禁止库所集集合的求解算法;最后,根据禁止库所集集合构造了"逻辑或"形式... 详细信息

针对不可控影响子网为α网的一类Petri网,提出了将给定的广义互斥约束转换成最优允许线性约束的方法.该方法首先获得了该网的不可控影响子网;其次,提出了转换后的禁止库所集集合的求解算法;最后,根据禁止库所集集合构造了"逻辑或"形式的最大允许线性约束.并且通过一个例子,说明了该方法的有效性.

关键词： Petri网离散事件系统禁止状态不可控变迁

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