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Journal of International Education and Practice 2019年第1期2卷 1-14页

作者： Jing Zhao xiaojing zou Wenpeng Shang Institutional Research Old Dominion UniversityNorfolkUnited States Chinese and Culture College Beijing Normal UniversityBeijingChina College of Foreign Studies Jinan UniversityGuangzhouChina

The purpose of the study was to further investigate the validity of the instrument used for col-lecting preservice teachers'perceptions of sel-fficacy adapting the three-level hierarchical generalized linear modeling(HGLM)*** serve the purpose,the study used data collct-ed by the research team which elicited preservice teachers'self-efficacy beliefs using Teachers'Sense of Efficacy Scale(TSES).HGLM were used to analyze the *** of the HGLM analyses(at level-two)showed that one item in the scale displayed gender *** item became DIF item when the context variable was added to the level-two ***,the effect of the context on the DIF item was not big.

关键词： HGLM Teachers'Sense of Efficacy Scale DIF

A Collaborative Medical Diagnosis System Without Sharing Patient Data

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ZTE Communications 2022年第3期20卷 3-16页

作者： NAN Yucen FANG Minghao zou xiaojing DOU Yutao Albert Y.ZOMAYA College of Intelligence Science and Technology National University of Defense TechnologyChangsha 410003China Tongji Hospital Tongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430074China Center for Distributed and High Performance Computing University of SydneySydney 2008Australia

As more medical data become digitalized,machine learning is regarded as a promising tool for constructing medical decision support *** with vast medical data volumes,machine learning is still not fully exploiting its potential because the data usually sits in data silos,and privacy and security regulations restrict their access and *** address these issues,we built a secured and explainable machine learning framework,called explainable federated XGBoost(EXPERTS),which can share valuable information among different medical institutions to improve the learning results without sharing the patients’ *** also reveals how the machine makes a decision through eigenvalues to offer a more insightful answer to medical *** study the performance,we evaluate our approach by real-world datasets,and our approach outperforms the benchmark algorithms under both federated learning and non-federated learning frameworks.

关键词： explainable machine learning federated learning secured data analysis medical applications

Post-mortem tissue proteomics reveals the pathogenesis of multi-organ injuries of COVID-19

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National Science Review 2021年第11期8卷 88-91页

作者： Yang Qiu Di Wu Wanshan Ning Jiqian Xu Ting Shu Muhan Huang Rong Chen Jiancheng Zhang Yang Han Qingyu Yang Ruiting Li Xiaobo Yang Yaxin Wang xiaojing zou Shangwen Pan Chaolin Huang Yu Xue You Shang Xi Zhou State Key Laboratory of Virology Wuhan Institute of Virology Chinese Academy of Sciences Joint Laboratory of Infectious Diseases and Health Wuhan Institute of Virology and Wuhan Jinyintan Hospital Wuhan Institute of Virology Chinese Academy of Sciences Center for Translational Medicine Wuhan Jinyintan Hospital MOE Key Laboratory of Molecular Biophysics Hubei Bioinformatics and Molecular Imaging Key Laboratory Center for Artificial Intelligence Biology College of Life Science and Technology Huazhong University of Science and Technology Department of Clinical Laboratory Union Hospital Tongji Medical CollegeHuazhong University of Science and Technology Department of Critical Care Medicine Union Hospital Tongji Medical College Huazhong University of Science and Technology Joint Laboratory of Infectious Diseases and Health Wuhan Institute of Virology and Wuhan Jinyintan Hospital Wuhan Jinyintan Hospital Institute of Anesthesiology and Critical Care Medicine Union Hospital Tongji Medical CollegeHuazhong University of Science and Technology

Multi-organ injuries are a major complication of severe Coronavirus Disease2019 (COVID-19).However,its pathogenesis is barely ***,we profile host responses to fatal SARSCoV-2 infection by performing quantitative proteomics of 19 post-mortem samples of 8 different organs or tissues,including lungs,liver,intestine,kidney,

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Remimazolam besylate for sedation of postoperative patients in intensive care units: a phase I, open label, dose-finding study

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Chinese Medical Journal 2022年第17期135卷 2134-2136页

作者： Yun Tang Xiaobo Yang Huaqing Shu Yuan Yu Jiqian Xu Shangwen Pan xiaojing zou Shiying Yuan You Shang Department of Critical Care Medicine Union HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhanHubei 430022China

To the Editor:Remimazolam besylate is a novel,ultrashort-acting benzodiazepine with a rapid and a predictable onset and offset profile,no accumulation and extended effect,and independence of organ elimination.

关键词： finding independence elimination

Extracorporeal membrane oxygenation in adult patients with sepsis and septic shock: Why, how, when, and for whom

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Journal of Intensive Medicine 2024年第1期4卷 62-72页

作者： Hongling Zhang Youdong Xu Xin Huang Shunyin Yang Ruiting Li Yongran Wu xiaojing zou Yuan Yu You Shang Department of Critical Care Medicine Union HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhanHubei430022China Department of Intensive Care Unit Affiliated Lu’an HospitalAnhui Medical UniversityLu’anAnhui237000China

Sepsis and septic shock remain the leading causes of death in intensive care *** patients with sepsis fail to respond to routine treatment and rapidly progress to refractory respiratory and circulatory failure,necessitating extracorporeal membrane oxygenation(ECMO).However,the role of ECMO in adult patients with sepsis has not been fully *** to existing studies,ECMO may be a viable salvage therapy in carefully selected adult patients with *** choice of venovenous,venoarterial,or hybrid ECMO modes is primarily determined by the patient’s oxygenation and hemodynamics(distributive shock with preserved cardiac output,septic cardiomyopathy(left,right,or biventricular heart failure),or right ventricular failure caused by acute respiratory distress syndrome).Veno-venous ECMO can be used in patients with sepsis and severe acute respiratory distress syndrome when conventional mechanical ventilation fails,and early application of veno-arterial ECMO in patients with sepsis-induced refractory cardiogenic shock may be critical in improving their chances of *** ECMO is indicated,the choice of an appropriate mode and determination of the optimal timing of initiation and weaning are critical,particularly in an experienced ECMO ***,some special issues,such as ECMO flow,anticoagulation,and antibiotic therapy,should be noted during the management of ECMO support.

关键词： Extracorporeal membrane oxygenation Sepsis Shock Acute respiratory distress syndrome(ARDS) Septic cardiomyopathy Mod

脂多糖对心肌细胞缺氧诱导因子-1α表达的影响

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临床心血管病杂志 2010年第8期26卷 629-631页

作者：高翔毛奕邹晓静杨乐华中科技大学同济医院综合科武汉430030 华中科技大学协和医院心内科华中科技大学协和医院麻醉科华中科技大学同济医院急诊内科

目的:观察脂多糖(LPS)对心肌细胞损伤及缺氧诱导因子-1α(HIF-1α)表达的影响。方法:培养新生乳鼠心肌细胞,以LPS(1μg/ml)分别作用0～4h,建立脓毒症心肌抑制细胞模型,测定各时点细胞存活率、LDH漏出率、锥虫蓝摄取率及肌酸激酶(CK)活... 详细信息

目的:观察脂多糖(LPS)对心肌细胞损伤及缺氧诱导因子-1α(HIF-1α)表达的影响。方法:培养新生乳鼠心肌细胞,以LPS(1μg/ml)分别作用0～4h,建立脓毒症心肌抑制细胞模型,测定各时点细胞存活率、LDH漏出率、锥虫蓝摄取率及肌酸激酶(CK)活性。用免疫印迹法测定LPS对HIF-1α表达的影响。结果:LPS处理后,LDH漏出率、锥虫蓝摄取率及CK活性均明显上调,而细胞存活率下调,同时伴HIF-1α表达明显上调。结论:LPS能导致明显的心肌损伤;同时伴随HIF-1α表达明显上调,但HIF-1α在脓毒症心肌抑制中扮演的角色尚需进一步研究。

关键词：心肌抑制脂多糖缺氧诱导因子-1α

丹参酮ⅡA磺酸钠对TGF-β1诱导的心房纤维化效应的影响

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中国医院药学杂志 2023年第14期43卷 1550-1553页

作者：杨乐刘刚郝洪真邹晓静华中科技大学同济医学院附属同济医院急诊科/重症医学科湖北武汉430030 华中科技大学同济医学院药理学系湖北武汉430030 华中科技大学同济医学院附属协和医院重症医学科湖北武汉430022

目的:观察丹参酮ⅡA磺酸钠(sodium tanshinoneⅡA sulfonate,STS)对转换生长因子-β1(TGF-β1)诱导的心房纤维化效应的影响。方法:培养新生乳鼠心房成纤维细胞。MTT比色法测定心房成纤维细胞增殖率,[3H]脯氨酸掺入测定心房成纤维细胞合... 详细信息

目的:观察丹参酮ⅡA磺酸钠(sodium tanshinoneⅡA sulfonate,STS)对转换生长因子-β1(TGF-β1)诱导的心房纤维化效应的影响。方法:培养新生乳鼠心房成纤维细胞。MTT比色法测定心房成纤维细胞增殖率,[3H]脯氨酸掺入测定心房成纤维细胞合成胶原速率。共聚焦荧光显微镜及Western blot检测Ⅰ/Ⅲ型胶原表达、Smad2磷酸化及核转移。结果:TGF-β1处理24 h后,心房成纤维细胞增殖明显增强,同时Ⅰ/Ⅲ型胶原表达及Smad2磷酸化/核转移亦明显增强。丹参酮ⅡA磺酸钠各浓度组以上效应均减弱。结论:丹参酮-ⅡIA磺酸钠能明显减轻TGF-β1诱导的心房纤维化效应,机制与调控Smad2磷酸化及核转移相关。

关键词：丹参酮-ⅡA磺酸钠心房纤维化转化生长因子-β1

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基于XML的异构数据库系统的研究

微计算机信息 2007年第24期23卷 160-162页

作者：邹晓静刘伟卢贤玲解放军信息工程大学电子技术学院401教研室

提出了利用XML解决异构数据库信息共享和透明访问的方案。介绍了数据库的异构性,XML的技术特点。通过基于XML的信息建模,以及XML文档和数据库模式之间的模板映射,实现了异构数据库之间的透明访问。提出了XML数据仓库的模型,结合XML和数... 详细信息

提出了利用XML解决异构数据库信息共享和透明访问的方案。介绍了数据库的异构性,XML的技术特点。通过基于XML的信息建模,以及XML文档和数据库模式之间的模板映射,实现了异构数据库之间的透明访问。提出了XML数据仓库的模型,结合XML和数据仓库的优势,实现了异构数据源的信息共享和决策支持。

关键词：异构数据库 XML 信息共享数据仓库

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猫适口性的影响因素和评价方法研究进展

中国饲料 2023年第3期 107-110页

作者：邹小敬徐赓王帅玉中国农业大学动物医学院北京100193 山东省沂南县畜牧发展促进中心山东临沂276300 中国农业大学中兽医药创新中心北京100193

随着人们物质生活水平的提高,越来越多的人选择饲养伴侣动物来丰富精神生活。猫咪已经成为我国最受欢迎的伴侣动物之一,据《2021中国宠物行业白皮书》显示,相较于宠物犬,宠物猫的饲养量有明显上升,且多分布于一线城市。猫粮和猫罐头作... 详细信息

随着人们物质生活水平的提高,越来越多的人选择饲养伴侣动物来丰富精神生活。猫咪已经成为我国最受欢迎的伴侣动物之一,据《2021中国宠物行业白皮书》显示,相较于宠物犬,宠物猫的饲养量有明显上升,且多分布于一线城市。猫粮和猫罐头作为养猫刚需,其需求量也随之攀升。在科学养宠的风潮下,适口性作为一种评价猫粮吸引力的方法也成为了一个热门话题。本文将对猫适口性的影响因素和评价方法进行综述。

关键词：猫饮食行为适口性饲料

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基于数据仓库题库分析子系统的分析与设计

微计算机信息 2006年第7X期22卷 222-223页

作者：卢贤玲邹晓静陈震解放军信息工程大学电子技术学院 450004 河南有色岩土工程公司 450007

题库系统作为一种教育测量工具,应具有考试分析功能以提高其利用率及教学质量。该文详细论述了如何实现题库分析子系统数据仓库模型的设计和实现,并对该子系统各主要模块功能进行了详细分析。

关键词：分析系统数据模型数据仓库