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A Self-sensing TSA-actuated Anthropomorphic Robot Hand

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Journal of Bionic Engineering 2024年第3期21卷 1174-1190页

作者： Chanchan Xu Shuai Dong Yifan Ma Jingwei Zhan Yucheng wang xiaojie wang Institute of Intelligent Machines Hefei Institutes of Physical ScienceChinese Academy of SciencesHefei230031China CAS Key Laboratory of Mechanical Behavior and Design of Materials Department of Precision Machinery and Precision InstrumentationUniversity of Science and Technology of ChinaHefei230026China Institutes of Physical Science and Information Technology Anhui UniversityHefei230601China

This paper introduces a self-sensing anthropomorphic robot hand driven by Twisted String Actuators(TSAs).The use of TSAs provides several advantages such as muscle-like structures,high transmission ratios,large output forces,high efficiency,compactness,inherent compliance,and the ability to transmit power over ***,conventional sensors used in TSA-actuated robotic hands increase stiffness,mass,volume,and complexity,making feedback control *** address this issue,a novel self-sensing approach is proposed using strain-sensing string based on Conductive Polymer Composite(CPC).By measuring the resistance changes in the strain-sensing string,the bending angle of the robot hand's fingers can be estimated,enabling closed-loop control without external *** developed self-sensing anthropomorphic robot hand comprises a 3D-printed structure with five fingers,a palm,five self-sensing TSAs,and a 3D-printed *** studies validate the self-sensing properties of the TSA and the anthropomorphic robot ***,a real-time Virtual Reality(VR)monitoring system is implemented for visualizing and monitoring the robot hand's movements using its self-sensing *** research contributes valuable insights and advancements to the field of intelligent prosthetics and robotic end grippers.

关键词： Anthropomorphic robot hand Twisted string actuator Self-sensing Conductive polymer composite Virtual reality monitoring

A survey on semantic communications:Technologies,solutions,applications and challenges

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Digital Communications and Networks 2024年第3期10卷 528-545页

作者： Yating Liu xiaojie wang Zhaolong Ning MengChu Zhou Lei Guo Behrouz Jedari School of Communication and Information Engineering Chongqing University of Posts and TelecommunicationsChongqing 400065China Baotou Vocational&Technical College Baotou 014035China School of Information and Electronic Engineering Zhejiang Gongshang UniversityHangzhou 310018China Department of Electrical and Computer Engineering New Jersey Institute of TechnologyNewarkNJ 07102USA Nokia Finland

Semantic Communication(SC)has emerged as a novel communication paradigm that provides a receiver with meaningful information extracted from the source to maximize information transmission throughput in wireless networks,beyond the theoretical capacity *** the extensive research on SC,there is a lack of comprehensive survey on technologies,solutions,applications,and challenges for *** this article,the development of SC is first reviewed and its characteristics,architecture,and advantages are ***,key technologies such as semantic extraction,semantic encoding,and semantic segmentation are discussed and their corresponding solutions in terms of efficiency,robustness,adaptability,and reliability are *** of SC to UAV communication,remote image sensing and fusion,intelligent transportation,and healthcare are also presented and their strategies are ***,some challenges and future research directions are presented to provide guidance for further research of SC.

关键词： Semantic communication Semantic coding Semantic extraction Semantic communication framework Semantic communication applications

Glutathione-depleted cyclodextrin pseudo-polyrotaxane nanoparticles for anti-inflammatory oxaliplatin(Ⅳ) prodrug delivery and enhanced colorectal cancer therapy

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Chinese Chemical Letters 2024年第4期35卷 280-286页

作者： Wenjia wang Xingyue He xiaojie wang Tiantian Zhao Osamu Muraoka Genzoh Tanabe Weijia Xie Tianjiao Zhou Lei Xing Qingri Jin Hulin Jiang State Key Laboratory of Natural Medicines China Pharmaceutical UniversityNanjing 210009China Faculty of Pharmacy Kinki University HigashiosakaOsaka 577-8502Japan State Key Laboratory of Natural Medicines(SKLNM)and Department of Medicinal Chemistry School of PharmacyChina Pharmaceutical UniversityNanjing 210009China School of Pharmacy Hangzhou Medical CollegeHangzhou 311399China College of Pharmacy Yanbian UniversityYanji 133002China

Oxaliplatin(Oxa) is the first-line chemotherapeutic drug for the treatment of colorectal cancer(CRC). However, long-term Oxa chemotherapy can induce inflammation and increase the levels of cyclooxygenase-2(COX-2) and prostaglandin E2(PGE2), which can promote tumor metastasis. Moreover,high glutathione(GSH) levels in CRC cells significantly reduce Oxa sensitivity and seriously restrict the clinical application of Oxa. Herein, an Oxa(Ⅳ) prodrug with anti-inflammatory properties(desmethyl naproxe, DN) and GSH-depleting cyclodextrin pseudo-polyrotaxane carriers were prepared and further self-assembled into micellar nanoparticles(designated DNPt@PPRI). The relesae of DN from DNPt@PPRI can reduce the level of PGE2 to inhibit inflammation and tumor metastasis by decreasing COX-2 protein,and also synergize with Oxa to inhibit tumor. More importantly, GSH depletion can reduce the detoxification of Oxa and further enhance chemotherapy-induced apoptosis. DNPt@PPRI have a good GSH depletion ability to enhance the sensitivity of Oxa, indicating a potential in the synergistic chemotherapy and chemo-sensitization of colorectal cancer.

关键词： Oxaliplatin Glutathione depletion Tetravalent platinum prodrug Synergistic therapy Colorectal cancer

Mating behaviors in ovoviviparous black rockfish(Sebastes schlegelii):molecular function of prostaglandin E2 as both a hormone and pheromone

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Marine Life Science & Technology 2024年第1期6卷 15-30页

作者： Likang Lyu Yijia Yao Songyang Xie xiaojie wang Haishen Wen Yun Li Jianshuang Li Chenpeng Zuo Shaojing Yan Jingyi Dong Xin Qi Key Laboratory of Mariculture(Ocean University of China) Ministry of EducationOcean University of ChinaQingdao 266003China Institute of Evolution and Marine Biodiversity Ocean University of ChinaQingdao 266003China

Prostaglandins(PGs)are profound hormones in teleost sexual behavior,especially in *** act as pheromones that affect the olfactory sensory neurons of males,inducing the initiation of a series of mating ***,the molecular mechanism by which PGs trigger mating behavior in ovoviviparous teleosts is still *** the present study,we employed the ovoviviparous black rockfish(Sebastes schlegelii),an economically important marine species whose reproductive production is limited by incomplete fertilization,as a model *** results showed that when the dose of PGE2 was higher than 10 nmol/L,a significant(P<0.05)increase in mating behaviors was ***-fluorescence in situ hybridization indicated that PGE2 could fire specific neurons in different brain regions and receptor cells in the olfactory *** combining with specific neurons in the central nervous system(CNS),a series of genes related to reproduction are *** intracerebroventricular administration of PGE_(2) significantly increased lhb levels(P<0.05)in both ***,steroidogenesis in gonads was also affected,inducing an increase(P<0.05)in E_(2) levels in males and T levels in ***_(2) levels were also increased significantly(P<0.05)in both *** present study revealed that PGE2 can activate mating behavior in black rockfish in both hormone and pheromone pathways,leading to variations in sex steroid levels and activation of reproductive *** results provide not only novel insight into the onset of mating behaviors in ovoviviparous teleosts but also solutions for the incomplete fertilization caused by natural mating in cage aquaculture.

关键词： Black rockfish Mating behavior Ovoviviparity Prostaglandin E2

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结肠癌手术相关韧带结构的膜解剖认识

中华胃肠外科杂志 2024年第9期27卷 898-903页

作者：王枭杰福建医科大学附属协和医院结直肠外科福州350001

与结肠癌手术相关的韧带主要包括胃结肠韧带、膈结肠韧带和脾结肠韧带。在传统开放手术年代,外科医师常通过大把钳夹结扎处理韧带。近年来,随着膜解剖研究的兴起与发展,结直肠外科医师在高清腹腔镜视野的协助下,逐步对各传统解剖结构逐... 详细信息

与结肠癌手术相关的韧带主要包括胃结肠韧带、膈结肠韧带和脾结肠韧带。在传统开放手术年代,外科医师常通过大把钳夹结扎处理韧带。近年来,随着膜解剖研究的兴起与发展,结直肠外科医师在高清腹腔镜视野的协助下,逐步对各传统解剖结构逐本溯源,基于膜解剖理念的手术更趋于精细化。本文结合笔者解剖学研究观察结果,对与结肠癌手术相关韧带的膜解剖本质进行辨析,并探讨其手术学和肿瘤学意义。胃结肠韧带在网膜囊区和非网膜囊区具有不同的膜解剖结构。在网膜囊区,除结肠旁路径以外,网膜弓下路径亦是从胃结肠韧带进入网膜囊的备选方法。在非网膜囊区,切开覆盖于胃系膜横结肠系膜间隙表面的大网膜是进入该间隙的膜桥。横结肠癌和结肠肝曲癌发生网膜弓淋巴结转移的概率很低,筛选该组淋巴结转移的高危患者进行清扫,仍具有生存获益。脾结肠韧带由胃背侧系膜的脾门区结构(包含胰腺系膜)和结肠脾曲系膜互相紧靠融合形成,其间存在天然无血分离平面,在该路径内分离可避免遭遇传统分离路径中遇到的胃网膜左动脉分支。目前尚无证据支持脾曲结肠癌需行脾门区胃背侧系膜组织切除或胃网膜弓淋巴结清扫。

关键词：结肠肿瘤手术韧带膜解剖胃网膜弓淋巴结胰腺系膜

Construction of laser-induced graphene/silver nanowire composite structures for low-strain, high-sensitivity flexible wearable strain sensors

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Science China Technological Sciences 2024年

作者： YANG PingAn ZHAO JingYuan LI Rui ZHOU ZhiHao GUI YinGang SUN RuiXue WU DeCheng wang xiaojie School of Automation Chongqing University of Posts and Telecommunications College of Engineering and Technology Southwest University Bio-inspired Robotics and Intelligent Material Laboratory Institute of Advanced Manufacturing Technology Hefei Institutes of Physical Science Chinese Academy of Sciences

Sandwich-structured flexible sensors based on graphene have high sensitivity and stability. When graphene is combined with a flexible substrate in a sandwich structure, the weak bonding between them compromises the sensor's stability and sensitivity at low strains. This presents challenges in monitoring subtle physiological activities, such as hand bending and pulse rate. For this purpose, laser-induced graphene(LIG) is proposed to be used to prepare flexible sensors in order to improve the sensitivity and stability of the sensors at low strains. Polydimethylsiloxane(PDMS) with low modulus and polyimide(PI) with rich carbon content are selected as precursor materials for LIG, and graphene is formed through laser induction. Subsequently, silver nanowires(Ag NWs) solution is added to LIG to give the sensor low strain and high sensitivity performance. When the PI/PDMS ratio is 1:3, the Ag NWs/LIG flexible strain sensor exhibits excellent sensitivity(GF=778.468) over a small strain range(8.76%-11.25%). Meanwhile, the sensor still shows excellent stability after 2000 cycle experiments. The Ag NWs/LIG flexible strain sensor shows good performance when placed on the back of the hand, around the eyes, etc. It is demonstrated that Ag NWs/LIG flexible strain sensors have good application potential in human physiological activity monitoring, health management and medical fields, and provide a low-strain, high-sensitivity sensor design strategy for flexible wearable devices.

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超越与经世:熊十力人生哲学的两大面向

广东社会科学 2024年第2期 83-91页

作者：王晓洁陕西省社会科学院西安710065

熊十力的人生哲学产生于近现代内忧外患的民族危机之中,建基于体用不二的本体论之上,承载着他志在提升国人道德、赓续中华文化的人生理想,彰显着他刚健不屈、积极向上的人生态度。这一人生哲学具有超越与经世两大基本面向,实现了形上与... 详细信息

熊十力的人生哲学产生于近现代内忧外患的民族危机之中,建基于体用不二的本体论之上,承载着他志在提升国人道德、赓续中华文化的人生理想,彰显着他刚健不屈、积极向上的人生态度。这一人生哲学具有超越与经世两大基本面向,实现了形上与形下的统一,为国人道德的自我完善提供了一条具有民族性和时代性的实践路径,代表了中国近现代知识分子为挽救民族危亡和世道人心所做的一种理论探索与现实努力。

关键词：超越经世人生哲学修养工夫

人口老龄化与少子化趋势下税收政策的应对策略

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经济与管理 2024年第4期38卷 70-76页

作者：王晓洁河北经贸大学财政税务学院河北石家庄050061

人口老龄化和少子化是当前我国经济社会发展面临的基本国情,对我国社会经济发展既有挑战和冲击,也有机遇。一方面,老龄化、少子化会带来人口红利的消失,与养老相关的财政支出压力增大,并通过影响消费需求、劳动参与率、劳动力成本等因... 详细信息

人口老龄化和少子化是当前我国经济社会发展面临的基本国情,对我国社会经济发展既有挑战和冲击,也有机遇。一方面,老龄化、少子化会带来人口红利的消失,与养老相关的财政支出压力增大,并通过影响消费需求、劳动参与率、劳动力成本等因素对税基产生影响。另一方面,人口老龄化会也会带来新的发展机遇,如用工成本增加倒逼企业进行技术创新、老年人口增加助力银发经济崛起等,为税收征收开辟新的增长点。为此,我国税收政策要积极适应老龄化、少子化带来的新变化,积极应对挑战,抓住机遇,调整完善有利于促进生育、促进企业技术创新、助推银色经济发展、促进低龄老年人再就业的税收政策,以促进老龄化进程中的经济发展和社会稳定,为未来的可持续发展奠定基础。

关键词：人口老龄化、少子化挑战与机遇税收政策

TGase催化的壳寡糖糖基化修饰玉米肽的抗氧化活性

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中国油脂 2024年第9期49卷 43-49页

作者：童玲王晓杰齐齐哈尔大学食品与生物工程学院黑龙江齐齐哈尔161006

为进一步提高玉米肽的抗氧化活性,以玉米醇溶蛋白源活性肽为原料,利用谷氨酰胺转氨酶(TGase)催化壳寡糖(分子质量1500 Da)与玉米肽共价结合制备玉米糖肽,研究壳寡糖的糖基化修饰对玉米肽抗氧化活性的影响,并对玉米糖肽进行体外模拟胃肠... 详细信息

为进一步提高玉米肽的抗氧化活性,以玉米醇溶蛋白源活性肽为原料,利用谷氨酰胺转氨酶(TGase)催化壳寡糖(分子质量1500 Da)与玉米肽共价结合制备玉米糖肽,研究壳寡糖的糖基化修饰对玉米肽抗氧化活性的影响,并对玉米糖肽进行体外模拟胃肠消化,表征玉米糖肽在体内发挥抗氧化活性的潜力。结果表明:TGase催化的壳寡糖共价结合使玉米肽的肽含量和体外消化率显著提高;在质量浓度为2.0 mg/mL时,TGase催化壳寡糖糖基化修饰使玉米肽的DPPH自由基、羟自由基、超氧阴离子自由基清除率,Fe^(2+)螯合率和还原力提高,体外消化使玉米糖肽的DPPH自由基、羟自由基清除率和还原力提高,而Fe^(2+)螯合率和超氧阴离子自由基清除率降低。综上,TGase途径的壳寡糖糖基化反应使玉米肽的抗氧化活性显著提高,且体外消化可以促进玉米糖肽抗氧化活性的释放(Fe^(2+)螯合能力和超氧阴离子自由基清除能力除外)。

关键词：玉米肽壳寡糖玉米糖肽体外消化抗氧化活性