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Direct observation of hydrogen-trapping sites in newly developed high-strength mooring chain steel by atom probe tomography

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Progress in Natural Science:Materials International 2013年第4期23卷 446-452页

作者： Xiaoying Cheng Zhijuan Zhang Wenqing Liu xiaojiao wang Laboratory for Microstructures Shanghai University Institute of Materials Shanghai University

Hydrogen-trapping sites were directly observed by using a three-dimensional atom probe(3DAP) in high-strength mooring chain *** typical 3DAP datasets show that trapping hydrogen is mainly enriched in retained austenite,and secondarily in *** addition,these interfaces between ferrite and carbide are segregated by phosphorus,but do not admit hydrogen.

关键词： Steel Hydrogen-trapping sites Atom probe tomography High-strength Retained austenite Interfaces

Catalytic effects of V-and O-species derived from PrF_(3)/V_(2)C for efficient hydrogen storage in MgH_(2)

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Nano Research 2024年第8期17卷 7117-7125页

作者： Zhenluo Yuan Yuhang wang Xiuxiu Zhang Shuyan Guan xiaojiao wang Liqiang Ji Qiuming Peng Shumin Han Yanping Fan Baozhong Liu College of Chemistry and Chemical Engineering Henan Polytechnic UniversityJiaozuo 454000China Henan Famous Diamond Co. Ltd.Mengzhou 454763China School of Chemical Engineering Zhengzhou UniversityZhengzhou 450001China Collaborative Innovation Center of Steel Technology University of Science and Technology BeijingBeijing 100083China State Key Laboratory of Metastable Materials Science and Technology Yanshan UniversityQinhuangdao 066004China

Magnesium hydride(MgH_(2))is considered as an ideal hydrogen storage material with excellent hydrogen capacity,but the slow kinetics impedes its ***,an efficient additive of V2C MXene-anchored PrF_(3) nanoparticles(PrF_(3)/V_(2)C)was synthesized,which presents excellent catalytic effect in improving the reversibility and stability of hydrogen storage in MgH_(2).The initial dehydrogenation temperature of the 5 wt.% PrF_(3)/V_(2)C-containing MgH_(2)(182℃) is 105℃ lower than that of pure MgH_(2),and 6.5 wt.%hydrogen is rapidly released from 5 wt.%PrF_(3)/V_(2)C-added MgH_(2)sample in 6 min at 240℃.In addition,5 wt.%PrF_(3)/V_(2)C-containing MgH_(2) sample possesses outstanding reversible hydrogen storage capability of 6.5 wt.% after 10 cycles of dehydrogenation and *** analysis shows that the introduction of Pr improves the stability of V-species(V^(0)and V^(2+))and O-species(lattice oxygen(OL)and vacancy oxygen(OV))formed during ball milling,promotes the interaction between V-species and O-species,and enhances their reversibility,which contributes to the significant improvement in re/dehydrogenation reversibility and cycling stability of MgH_(2).This study provides effective ideas and strategies for the purpose of designing and fabricating high-efficient catalysts for solid-state hydrogen storage materials.

关键词： hydrogen storage materials MgH_(2) dehydrogenation reversibility cyclic stability

Size-selective hybridization chain reaction for accurate signal amplification in living cancer cells

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Science China Chemistry 2024年第12期67卷 4259-4266页

作者： Ting Chen xiaojiao wang Rongrong Gao Meihe Yuan Mei Chen Xiao-Bing Zhang Guoliang Ke State Key Laboratory of Chemo/Biosensing and Chemometrics College of Chemistry and Chemical EngineeringCollege of Materials Science and EngineeringHunan UniversityChangsha 410082China

Accurate signal amplification in living cells is highly important in biomedical research and medical *** from its enzyme-free,efficient isothermal signal amplification ability,hybridization chain reaction(HCR)plays an important role in intracellular signal amplification;however,HCR fails the accurate signal amplification in the situation when the properties of some biological targets and analogues are too ***,their signal amplification accuracy for mature mi RNAs is unsatisfactory due to the signal interference of precursor micro RNAs(abbreviated as pre-mi RNAs),which also contain the sequence of mature mi ***,we develop the first example of size-selective hybridization chain reaction probe for accurate signal amplification,which achieved accurate and sensitive biosensing of mature mi RNAs in living cancer *** probe,termed as q Tcage,consists of a DNA nanocage for size-selective responsive to mature mi RNAs,as well as a quadrivalent tetrahedral DNA structure for HCR signal *** from the size-selectivity of DNA nanocage,shorter mature mi RNAs(19–23 nt)rather than longer pre-mi RNAs(60–70 nt)could enter the cavity to release triggers strand,which activates HCR reaction for fluorescence signal *** probe efficiently reduces signal interference of pre-mi RNAs and improves the imaging sensitivity for intracellular mature mi RNAs,which was successfully applied for mature mi RNAs imaging during drug ***,this strategy provides the hybridization chain reaction with the feature of size-selective ability,which holds promise for further accurate signal amplification in biological processes study and clinical diagnostics.

关键词： hybridization chain reaction microRNA DNA nanotechnology

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The Ap-2α/Elk-1 axis regulates Sirpα-dependent tumor phagocytosis by tumor-associated macrophages in colorectal cancer

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Signal Transduction and Targeted Therapy 2020年第1期5卷 2065-2076页

作者： xiaojiao wang Xi Luo Chuan Chen Ye Tang Lian Li Banghui Mo Houjie Liang Songtao Yu Department of Oncology Southwest HospitalArmy Medical University30 Gaotanyan StreetChongqing 400038People’s Republic of China Cancer Center Daping Hospital and Research Institute of SurgeryArmy Medical UniversityChongqing 402560People’s Republic of China Department of Oncology Tong Liang District HospitalChongqing 402560People’s Republic of China

The inhibitory receptor signal regulatory protein-α(Sirpα)is a myeloid-specific immune checkpoint that engages the“don’t eat me”signal CD47,which is expressed on tumor and normal tissue ***,the profile and regulatory mechanism of Sirpαexpression in tumor-associated macrophages(TAMs)are still not ***,we found that the expression of Sirpαin TAMs increased dynamically with colorectal cancer(CRC)***,CRC cell-derived lactate induced the nuclear translocation of the transcription factor Ap-2αfrom the cytoplasm in ***-2αfunctioned as a transcription factor for Elk-1 by binding to the conserved element GCCTGC located at−1396/−1391 in the mouse Elk-1 ***,the Elk-1 protein bound to two conserved sites,CTTCCTACA(located at−229/−221)and CTTCCTCTC(located at−190/−182),in the mouse Sirpαpromoter and promoted Sirpαexpression in ***,the macrophage-specific knockout of Ap-2αnotably promoted the phagocytic activity of TAMs and suppressed CRC progression,whereas these effects were prevented by the transgenic macrophage-specific expression of Elk-1,which regulated TAM phagocytosis and CRC development in a Sirpα-dependent ***,we showed that Elk-1 expression was positively correlated with Sirpαexpression in TAMs and was associated with poor survival in CRC *** together,our findings revealed a novel mechanism through which CRC evades innate immune surveillance and provided potential targets for macrophage-based immunotherapy for CRC patients.

关键词： colorectal cancer promoted

Midwives’views and experiences of providing midwifery care in the task shifting context:a meta-ethnography approach

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Global Health Journal 2020年第3期4卷 96-106页

作者： Chunyi Gu xiaojiao wang Lingling Li Yan Ding Xu Qian Nursing Department Obstetrics and Gynecology HospitalFudan University419 Fangxie RoadShanghai 200011China School of Public Health Fudan University138Yi Xue Yuan RoadShanghai 200032China Department of Obstetrics Shanghai Changzheng Hospitalthe Second Military Medical University415 Fengyang RoadShanghai 200003China Global Health Institute Fudan University138Yi Xue Yuan RoadShanghai 200032China

Objective:This study aimed to explore the existing knowledge about midwives’views and experiences of providing care for women in the context of task ***:We conducted a qualitative systematic review using meta-ethnography to describe the views and experiences of midwives on providing care in the context of task *** textual analysis of published qualitative studies involved translation of first-order key concepts and meanings from included studies to generate second-and third-order concepts.A grid was made to identify core findings and compare them ***:Thirty-six qualitative studies met the inclusion *** literature comprised of 32 first key *** second-order constructs emerged,and three third-order interpretations were *** three overarching themes were:(1)midwives perceived themselves as providing culturally competent and high quality women-centered care;(2)they valued their profession but saw it as complex and challenging;(3)as health professionals,they reported a variety of organizational,cultural,and professional barriers to providing women-centered ***:While performing a specific task in the task shifting context,midwives perceived their crucial roles and responsibilities,along with achieved value and ***,due to a range of existing barriers,the caring task posed great challenges in completely implementing women-centered *** is essential for systems to identify and eliminate these barriers early,to consider midwives’emotional well-being,and to develop overall strategies to better support the midwifery *** makers and administrators should establish a supportive environment to facilitate midwives to perform women-centered caring tasks in more effective and efficient ways.

关键词： Midwifery care Midwives Meta-ethnography Qualitative study Task shifting

World Attention Focuses on China Tourism——The First World Summit of Tourism Promotion to be Held in Nanjing Grandly

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中国周刊 2004年第7期 12-13页

作者： wang xiaojiao

The Press Conference of the First World Summit of Tourism Promo tion was held in Nanjing on July 28. The summit would be a major event in tourism development in our country. It is known that initiated by World Trade University of UN and intended to promote the globalization of tourism, the UN Global Partnership Program, - the First World Summit of Tourism Promotion is to be held in Nanjing, China, in November, *** World Summit of Tourism Pro-

关键词： World Attention Focuses on China Tourism The First World Summit of Tourism Promotion to be Held in Nanjing Grandly

Anastomosis Groups and Pathogenicity of Rhizoctonia solani from Potato in Inner Mongolia

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Plant Diseases and Pests 2019年第1期10卷 18-23页

作者： Cao Chunmei wang xiaojiao Xu Fei Lu Chunxing Inner Mongolia Academy of Agricultural and Animal Husbandry Sciences Inner Mongolia Agricultural University

A total of 148 samples of potato black scurf were collected from 15 potato producing counties in Inner Mongolia Autonomous Region of China, and the strains were identified to be Rhizoctonia solani. The collected R. solani strains were grouped into three types, fast growth, slow growth and medium growth, based on the mycelial growth rate. Most of the fungi isolated were of fast and medium growth types. To examine the anastomosis groups of isolated R. solani strains, the isolated strains were co-cultured with anastomosis standard strains on sterile slide glass, and the occurrence of mycelial fusion was observed under microscope. The examination results indicated that 45 strains(73.77%), four strains(6.56%), and three strains(4.92%) belonged to AG-3, AG-1-IB and AG-2 anastomosis groups, respectively, while nine strains(14.75%) did not belong to any anastomosis groups above. These results suggested that the dominant strains causing potato black scurf in Inner Mongolia Autonomous Region were mainly R. solani AG-3. To test the pathogenicity of different anastomosis groups of R. solani, the potato tubers were planted with soil infected by isolated fungi. The results showed that all the tested fungi were able to cause typical symptoms of potato black scurf on tubers and stalk, but their pathogenicity levels varied. Moreover, it was found that the mycelial growth rate was positively correlated with their pathogenicity.

关键词： Rhizoctonia solani Mycelial growth rate Anastomosis group Pathogenicity

Experimental and modeling study of NO emission under high CO_2 concentration

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Science China(Technological Sciences) 2010年第12期53卷 3275-3283页

作者： ZHAO Ran, LIU Hao, HU Han, ZHONG xiaojiao, wang ZiJian, XU ZhiYing & QIU JianRong State Key Laboratory of Coal Combustion, Huazhong University of Science and Technology, Wuhan, 430074, China 1. State Key Laboratory of Coal Combustion Huazhong University of Science and Technology Wuhan 430074 China

An experimental and numerical study of the NOx formation and reduction process in a designed coal combustion furnace under both traditional air atmosphere and O2/CO2 atmosphere was conducted, in an attempt to explore the chemistry mechanism of the experimentally observed NOx suppression under high CO2 concentration atmospheres. A simplified ‘chemically oriented’ approach, computational fluid dynamics (CFD)-chemical kinetics modeling method, was validated and used to model the experimental process. The high CO2 concentration’s chemical effect on NO reduction has been studied, and the differences in NOx reaction behaviors between O2/CO2 atmosphere and air atmosphere were analyzed by detailed chemical kinetic model. On the basis of investigations through elementary chemical reactions, it can be concluded that high CO2 concentration plays an important role on NOx conversion process during oxy-fuel combustion. Moreover, the dominant reaction steps and the most important reactions for NO conversion under different atmospheres were discussed. Under O2/CO2 atmosphere, the main active sequence for NO reaction includes: NO→N→N2, and the main active path for NO reaction under air atmosphere is through N2→N→NO.

关键词： coal combustion chemical kinetics carbon dioxide nitric oxide

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Challenges and Teaching Reform Strategies in Vocational College Engineering Training Courses

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Journal of Contemporary Educational Research 2024年第7期8卷 323-330页

作者： Yueyi Li Xuesong Zhen Jinru Ma xiaojiao wang School of Automotive Engineering Beijing PolytechnicBeijing 100176China

With the rapid development of vocational education,engineering training has become a crucial course for cultivating highly skilled technical professionals,highlighting its ***,vocational college engineering training courses still face numerous challenges during the actual teaching process,which affect the effectiveness of course teaching and the enhancement of students’engineering *** article thoroughly analyzes the main problems existing in current engineering training course teaching,focusing on four aspects:students’cognitive differences,inadequate course development,poor course adaptability,and limited teaching *** on this analysis and previous research findings,targeted strategies are proposed,including enhancing students’course cognition,clarifying course positioning,improving course adaptability,and optimizing the allocation of teaching ***,this article preliminarily verifies the effectiveness of some reform strategies through a small-scale teaching *** study aims to provide theoretical guidance and practical reference for enhancing the teaching quality of vocational college engineering training courses.

关键词： Vocational colleges Engineering training Teaching reform Course development Practical teaching