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Robust Carbonated Structural Color Barcodes with Ultralow Ontology Fluorescence as Biomimic Culture Platform

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Research 2021年第1期2021卷 1354-1366页

作者： Panmiao liu Zhongde Mu Muhuo Ji xiaojiang liu Hanwen Gu Yi Peng Jianjun Yang Zhuoying Xie Fuyin Zheng Department of Anesthesiology Pain and Perioperative MedicineThe First Affiliated Hospital of Zhengzhou UniversityZhengzhouChina 450052 Jiangsu Cancer Hospital&Jiangsu Institute of Cancer Research&The Affiliated Cancer Hospital of Nanjing Medical University Nanjing 210009China Department of Anesthesiology The Second Affiliated HospitalNanjing Medical UniversityNanjingChina State Key Laboratory of Bioelectronics School of Biological Science and Medical EngineeringSoutheast UniversityNanjingChina 210096 Key Laboratory for Biomechanics and Mechanobiology Beijing Advanced Innovation Center for Biomedical EngineeringSchool of Biological Science and Medical EngineeringBeihang UniversityBeijing 100083China

Photonic crystal(PC)barcodes are a new type of spectrum-encoding microcarriers used in multiplex high-throughput bioassays,such as broad analysis of biomarkers for clinical diagnosis,gene expression,and cell ***,most of these existing PC barcodes suffered from undesired features,including difficult spectrum-signal acquisition,weak mechanical strength,and high ontology fluorescence,which limited their development to real *** address these limitations,we report a new type of structural color-encoded PC *** barcodes are fabricated by the assembly of monodisperse polydopamine-(PDA-)coated silica(PDA@SiO_(2))nanoparticles using a droplet-based microfluidic technique and followed by pyrolysis of PDA@SiO_(2)(C@SiO_(2))*** of the templated carbonization of adhesive PDA,the prepared C@SiO_(2)PC beads were endowed with simultaneous easy-to-identify structural color,high mechanical strength,and ultralow ontology *** demonstrated that the structural colored C@SiO_(2)barcodes not only maintained a high structural stability and good biocompatibility during the coculturing with fibroblasts and tumor cells capture but also achieved an enhanced fluorescentreading signal-to-noise ratio in the fluorescence-reading *** features make the C@SiO_(2)PC barcodes versatile for expansive application in fluorescence-reading-based multibioassays.

关键词： template maintained versatile

Electrochemical performance of NiCl_(2) with Br-free molten salt electrolyte in high power thermal batteries

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Science China(Technological Sciences) 2021年第1期64卷 91-97页

作者： CAO Yong LI Jian YANG Peng WEI KaiYuan MA ShiPing ZHANG XiaoQiang WU MeiFen liu xiaojiang CUI YanHua WEN ZhaoYin Institute of Electronic Engineering China Academy of Engineering PhysicsMianyang 621000China College of Materials Science and Engineering Chongqing UniversityChongqing 400044China State Key Laboratory of High Performance Ceramics and Superfine Microstructure Shanghai Institute of CeramicsChinese Academy of SciencesShanghai 200050China

NiCl_(2) with high theoretical voltage and thermal decomposition temperature attracts much attention as cathode material for thermal batteries with the requirement of high power density, high energy density and long work time. Unfortunately, the practical utilization of thermal batteries with NiCl_(2) cathode is limited by their poor electrochemical performance under large current, even with the conventional Li F-Li Cl-Li Br all-lithium molten salt electrolyte which proposes ultrahigh lithium ion conductivity. In this work, an unexpected ionic exchange reaction between NiCl_(2) and Li Br in Li F-Li Cl-Li Br was found, which would be the main reason for the poor electrochemical behavior of thermal batteries with NiCl_(2) cathode and Li F-Li Cl-Li Br molten salt. On this basis, Li F-Li Cl-Li_(2)SO_(4), another all-lithium molten salt free of Li Br, was investigated as the new electrolyte for NiCl_(2) cathode. For the single cell of Li(Si)/Li F-Li Cl-Li_(2)SO_(4)/NiCl_(2), a discharge capacity of 377 mA h g^(-1)(with a cut-off voltage of 1.2 V) was achieved with large current density(500 mA cm^(-2)) applied at 520℃, which is almost twice of that of Li(Si)/Li F-Li Cl-Li Br/NiCl_(2)(190 mA h g^(-1)) at the same conditions.

关键词： thermal battery molten salt electrolyte cathode material nickel chloride

Low-Volatile Binder Enables Thermal Shock-Resistant Thin-Film Cathodes for Thermal Batteries

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Energy & Environmental Materials 2024年第4期7卷 126-134页

作者： Yong Xie Yong Cao Xu Zhang Liangping Dong xiaojiang liu Yixiu Cui Chao Wang Yanhua Cui Xuyong Feng Hongfa Xiang Long Qie Laboratory of Electrochemical Power Sources Institute of Electronic EngineeringChina Academy of Engineering PhysicsMianyang 621000China School of Materials Science and Engineering Hefei University of TechnologyHefei 230009China State Key Laboratory of Material Processing and Die&Mold Technology School of Materials Science and EngineeringHuazhong University of Science and TechnologyWuhan 430074China

Manufacturing thin-film components is crucial for achieving high-efficiency and high-power thermal batteries(TBs).However,developing binders with low-gas production at the operating temperature range of TBs(400-550°C)has proven to be a significant ***,we report the use of acrylic acid derivative terpolymer(LA136D)as a low-volatile binder for thin-film cathode fabrication and studied the chain scission and chemical bondbreaking mechanisms in *** is shown LA136D defers to randomchain scission and cross-linking chain scission mechanisms,which gifts it with a low proportion of volatile products(ψ,ψ=39.2 wt%)at even up to 550°C,well below those of the conventional PVDF(77.6 wt%)and SBR(99.2 wt%)***,LA136D contributes to constructing a thermal shock-resistant cathode due to the step-by-step bond-breaking *** is beneficial for the overall performance of *** discharging test,the thin-film cathodes exhibited a remarkable 440%reduction in polarization and 300%enhancement in the utilization efficiency of cathode materials,while with just a slight increase of 0.05 MPa in gas pressure compared with traditional“thick-film”*** work highlights the potential of LA136D as a low-volatile binder for thin-film cathodes and shows the feasibility of manufacturing high-efficiency and high-power TBs through polymer molecule engineering.

关键词： gas production high-power low-volatile binder thermal battery thin-film cathode

Percutaneous coronary intervention following repair of type B aortic dissection:a report of 8 cases

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Journal of Geriatric Cardiology 2008年第2期5卷 79-82页

作者： Quanmin Jing Xiaozeng Wang Yaling Han Bo Luan Geng Wang xiaojiang liu Hongxu Jin Department of Cardiology Shenyang North ern HospitalShenyang 110016China

Objective Patients with aortic dissection have a significant incidence of coronary artery *** purpose of this study is to evaluate the safety and feasibility of percutaneous coronary stent in patients who have undergone endovascular stent,and to assess the effect of anti-coagulant and anti-platelet treatment on patients'thrombosis *** From January 2005 to July 2007,8 patients who had undergone endovascular stent-graft during the past 1 to 7 months for type B aortic dissection repair,underwent percutaneous coronary intervention(PCI)because of coexisting coronary artery ***-coagulant and anti-platelet treatments were administrated after PCI according to the standard *** were followed up for a mean period of 23 *** and false lumen status data were collected during the *** PCI were technically successful in all 8 patients and no severe complications such as death,paraplegia,renal failure occurred during *** false lumen thrombosis was observed in 5 patients and incomplete false lumen thrombosis in the remained 3 patients at the end of follow *** were no major complications such as death,dissection rupture or aneurysm development occurred during the follow-up *** Our data implied that PCI can be safely performed in patients with type B aortic dissection who have undergone endovascular stent-graft,without interrupt-ing the thrombosis process.

关键词： aortic dissection coronary artery disease percutaneous coronary intervention stent-graft

The Discussion of 500kv Centralized Monitoring System For Large Operation and Large Maintenance Mode

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Engineering（科研） 2013年第1期5卷 127-131页

作者： lingling Shuai xiaojiang liu Jun Li Jiangxi Electric Power Co. Maintenance Branch Nanchang China

The establishment of a centralized monitoring system is an effective means to achieve the goal that no or fewer people are on duty. The function of the current 500kV centralized monitoring system is not enough mature to meet the requirement of the large-scale operation and large-scale maintenance model proposed by the State Grid. In order to fully utilizing the function of the centralized monitoring system, an improved design scheme is presented for the current 500kV centralized monitoring of the Jiangxi Power Grid. The improved centralized monitoring system is divided into three layers: monitoring center layer, operating team layer, and substation layer, which not only has the advantages of high security, high reliability, and easy maintenance, but also realizes the management model of regional control. So it can perfectly meet anti-misoperation requirement in the large operation and large maintenance mode, which can provide reference and guidance for the design of the 500kV centralized monitoring system of Jiangxi Power Grid.

关键词： Centralized monitoring system Substation Anti-misoperation system Five-prevention system

Endovascular stent-grafts for acute and chronic type B aortic dissection: comparison of clinical outcomes

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Journal of Geriatric Cardiology 2007年第2期4卷 67-71页

作者： Quanming Jing Yaling Han Xiaozheng Wang Jie Deng Bo Luan Hongxu Jin xiaojiang liu Fei Li Ying liu Department of Cardiology General Hospital of Shenyang Military Region Shenyang China Department of Cardiology General Hospital of Shenyang Military Region Shenyang China Department of Cardiology General Hospital of Shenyang Military Region Shenyang China Department of Cardiology General Hospital of Shenyang Military Region Shenyang China Department of Cardiology General Hospital of Shenyang Military Region Shenyang China Liaoning Medical College China Department of Cardiology General Hospital of Shenyang Military Region Shenyang China Department of Cardiology General Hospital of Shenyang Military Region Shenyang China Department of Cardiology General Hospital of Shenyang Military Region Shenyang China

Objective To evaluate the early and mid-term results of endovascular repair for acute and chronic type B aortic dissection, and to compare the clinical outcomes between the 2 groups. Methods From May 2002 to December 2006, 50 patients with type B aortic dissection were treated by endovascular stent-graft. There were 23 patients in the acute aortic dissection (AAD) group and 27 patients in the chronic aortic dissection (CAD) group. All patients were followed up from 1 to 54 months (average, 17±16 months).The immediate and follow-up clinical outcomes were documented and compared between the 2 groups. Results Placement of endovascular stent-grafts across the primary entry tears was technically successful in all 50 patients. Compared to the CAD group, the AAD group had a higher percentage of pleural effusion (17.4% vs. 0%, P=0.04) and visceral /leg ischemia (26.1% vs 3.7%, P=0.04). Procedure related complications, including endoleak and post-implantation syndrome, occurred more frequently in the AAD group than in the CAD group (21.7% vs 3.7% and 30.4% vs 11.1%, respectively; P=0.08 and P=0.04). Kaplan–Meier analysis showed no difference in the survival rate at 4 years between the 2 groups (86.4% vs 92.3%, P=0.42 by log-rank test). However, the event-free survival rate was higher in patients with chronic dissection than in patients with acute aortic dissection(96.2% vs 73.9%; P=0.02 by log-rank test). Conclu- sions Endovascular repair with stent-graft was safe and effective for the treatment of both acute and chronic type B aortic dissection. However, both immediate and long term major complications occurred more frequently in patients with acute dissection than in those with chronic dissection.

关键词： aortic dissection endovascular repairing stent-graft

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改善HVDC动态特性的非线性附加控制

高电压技术 2005年第4期31卷 49-51页

作者：刘小江刘天琪刘群英四川大学电气信息学院成都610065

为进一步改善高压直流输电系统的性能,用状态反馈精确线性化方法设计了整流侧定直流电流、逆变侧定交流电压的非线性附加控制器,只需少量局部反馈信号便可获得良好的调节性能。数字仿真结果表明,该控制器能改善交直流系统的动态特性。

关键词：暂态稳定动态特性非线性附加控制器高压直流输电

Study on stabilities and electrochemical behavior of V(V) electrolyte with acid additives for vanadium redox flow battery

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Journal of Energy Chemistry 2014年第1期23卷 73-81页

作者： Gang Wang Jinwei Chen Xueqin Wang Jing Tian Hong Kang Xuejing Zhu Yu Zhang xiaojiang liu Ruilin Wang College of Materials Science and Engineering Sichuan University Institute of Electronics Engineering China Academy of Engineering Physics

Several acid compounds have been employed as additives of the V(V) electrolyte for vanadium redox flow battery(VRB) to improve its stability and electrochemical activity. Stability of the V(V) electrolyte with and without additives was investigated with ex-situ heating/cooling treatment at a wide temperature range of-5 ?C to 60 ?C. It was observed that methanesulfonic acid, boric acid, hydrochloric acid, trifluoroacetic acid,polyacrylic acid, oxalic acid, methacrylic acid and phosphotungstic acid could improve the stability of the V(V) electrolyte at a certain range of temperature. Their electrochemical behaviors in the V(V) electrolyte were further studied by cyclic voltammetry(CV), steady state polarization and electrochemical impedance spectroscopy(EIS). The results showed that the electrochemical activity, including the reversibility of electrode reaction, the diffusivity of V(V) species, the polarization resistance and the flexibility of charge transfer for the V(V) electrolyte with these additives were all improved compared with the pristine solution.

关键词： Cyclic voltammetry Electrochemical impedance spectroscopy Organic acids Secondary batteries Stability Vanadium compounds

Differential distribution of PINK1 and Parkin in the primate brain implies distinct roles

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Neural Regeneration Research 2025年第4期20卷 1124-1134页

作者： Yanting liu Wei Huang Jiayi Wen Xin Xiong Ting Xu Qi Wang Xiusheng Chen Xianxian Zhao Shihua Li xiaojiang Li Weili Yang Guangdong Key Laboratory of Non-human Primate Research Key Laboratory of CNS Regeneration(Ministry of Education)Guangdong-Hongkong-Macao CNS Regeneration Institute of Jinan UniversityJinan UniversityGuangzhouGuangdong ProvinceChina

The vast majority of in vitro studies have demonstrated that PINK1 phosphorylates Parkin to work together in mitophagy to protect against neuronal ***,it remains largely unclear how PINK1 and Parkin are expressed in mammalian *** has been difficult to address because of the intrinsically low levels of PINK1 and undetectable levels of phosphorylated Parkin in small *** this issue is critical for elucidating the in vivo roles of PINK1 and ***,we showed that the PINK1 kinase is selectively expressed as a truncated form(PINK1–55)in the primate *** the present study,we used multiple antibodies,including our recently developed monoclonal anti-PINK1,to validate the selective expression of PINK1 in the primate *** found that PINK1 was stably expressed in the monkey brain at postnatal and adulthood stages,which is consistent with the findings that depleting PINK1 can cause neuronal loss in developing and adult monkey ***1 was enriched in the membrane-bound fractionations,whereas Parkin was soluble with a distinguishable *** double staining experiments showed that PINK1 and Parkin did not colocalize under physiological conditions in cultured monkey astrocytes,though they did colocalize on mitochondria when the cells were exposed to mitochondrial *** findings suggest that PINK1 and Parkin may have distinct roles beyond their well-known function in mitophagy during mitochondrial damage.

关键词： neurodegeneration Parkin Parkinson’s disease PINK1 subcellular distribution