检索结果-南通市图书馆

Computational network pharmacological research of Chinese medicinal plants for chronic kidney disease

在线全文

学校读者我要写书评

暂无评论

Science China Chemistry 2010年第11期53卷 2337-2342页

作者： ZHU Wei qiu xiaohui XU XiaoJie LU ChuanJian Guangdong Hospital of Traditional Chinese Medicine Guangzhou 510006China College of Chemistry and Molecular Engineering Peking UniversityBeijing 100871China

The interaction between drug molecules and target proteins is the basis of pharmacological *** pharmacodynamic mechanism of Chinese medicinal plants for chronic kidney disease(CKD) was studied by molecular docking and complex network *** was found that the interaction network of components-proteins of Chinese medicinal plants is different from the interaction network of components-proteins of *** action mechanism of Chinese medicinal plants is different from that of *** also found the interaction network of components-proteins of tonifying herbs is different from the interaction network of components-proteins of evil expelling herbs using complex network research *** illuminates the ancient classification theory of Chinese medicinal *** computational approach could identify the pivotal components of Chinese medicinal plants and their key target proteins *** results provide data for development of multi-component Chinese medicine.

关键词： chronic kidney disease traditional Chinese medicine(TCM) molecular docking complex network

Friction of MoO_(3) Nanoflakes on Graphite Surface with an Ace-like Intercalation Layer

在线全文

学校读者我要写书评

暂无评论

Chemical Research in Chinese Universities 2022年第3期38卷 769-773页

作者： WEI Dawei ZHANG Guangjie LU Xiaoquan qiu xiaohui Tianjin Key Laboratory of Molecular Optoelectronic Department of ChemistrySchool of ScienceTianjin UniversityTianjin300072P.R.China CAS Key Laboratory of Standardization and Measurement for Nanotechnology CAS Center for Excellence in NanoscienceNational Center for Nanoscience and TechnologyBeijing100190P.R.China Key Laboratory of Bioelectrochemistry&Environmental Analysis of Gansu Province College of Chemistry&Chemical EngineeringNorthwest Normal UniversityLanzhou730070P.R.China University of Chinese Academy of Sciences Beijing100049P.R.China

How water layer adsorbed on solid surface under ambient conditions affects the interfacial friction is a fundamental question for understanding the friction and lubrication phenomena in practical *** investigate the formation of ice-like(IL)water layers on the hydrophobic surface of graphite with partially covered MoO_(3)nanoflakes(NFs)using atomic force microscopy(AFM)based *** IL water layers are found surrounding the MoO_(3)NFs and also intercalated at the MoO_(3)/graphite interface,as proved by thickness measurements as well as local adhesion force and surface potential *** manipulations carried out on MoO_(3)NFs on graphite show that the presence of the IL water layers increases the frictional resistance of the *** the results on continuous and discontinuous IL water layers,we can identify the different sliding interfaces in the two *** increased friction for MoO_(3)NFs sliding on graphite with an intercalated water layer is attributed to the energy dissipation originated from the metastable nature of the IL layers.

关键词： Friction Ice-like water MoO_(3) Graphite

Layer-dependent charge density wave phase transition stiffness in 1T-TaS_(2)nanoflakes evidenced by ultrafast carrier dynamics

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Nano Research 2021年第4期14卷 1162-1166页

作者： Rui Wang Junbo Zhou Xinsheng Wang Liming Xie Jimin Zhao xiaohui qiu CAS Key Laboratory of Standardization and Measurement for Nanotechnology CAS Center for Excellence in NanoscienceNational Center for.Nanoscience and TechnologyBeijing 100190China Beijing National Laboratory for Condensed Matter Physics Institute of PhysicsChinese Academy of SciencesBeijing 100190China Songshan Lake Materials Laboratory Dongguan 523808China University of Chinese Acadermy of Sciences Beijing 100049China

Novel physical properties emerge when the thickness of charge density wave(CDW)materials is reduced to the atomic level,owing to the significant modification of the electronic band structure and correlation ***,we investigate the layer-dependent CDW phase transition and evolution of the nonequilibrium state of 1T-TaS_(2)nanoflakes using pump-probe *** the low-energy single-particle and collective excitation relaxations exhibit sharp changes at〜210 K,indicating a phase transition from commensurate CDW to nearly commensurate CDW *** single particle process reveals that the phase transition stiffness(PTS)is ***,a small PTS is observed in thin nanoflakes,which is attributed to the reduced thickness that increases the fluctuation and inhibits the nucleation and growth of *** addition,the phase mode vanishes when the discommensuration network *** results suggest that the carrier dynamics could be an efficient operational approach to measuring the quantum phase transition in correlated materials.

关键词： charge density wave 1T-TaS_(2) layer-dependent phase transition stiffness ultrafast carrier dynamics

Orientation of molecular interface dipole on metal surface investigated by noncontact atomic force microscopy

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Science Bulletin 2013年第30期58卷 3630-3635页

作者： YUAN BingKai CHEN PengCheng ZHANG Jun CHENG ZhiHai qiu xiaohui WANG Chen National Center for Nanoscience and Technology

We investigated the orientations of interface dipole moments of individual non-planar titanyl phthalocyanine(TiOPc)molecules on Cu(111)and Cu(100)substrates using scanning tunneling microscope(STM)and noncontact atomic force microscope(NC-AFM).The dipole moment orientations corresponding to two different configurations of individual TiOPc molecules were determined *** correlation between the actual molecular structures and the corresponding STM topographies is proposed based on the sub-molecular resolution imaging and local contact potential difference(LCPD)*** with the pristine substrate,the LCPD shift due to the adsorption of non-planar molecule is dependent on the permanent molecular dipole,the charge transfer between the surface and the molecule,and the molecular *** work would shed light on tailoring interfacial electronic properties and controlling local physical properties via polar molecule adsorption.

关键词：原子力显微镜分子结构非接触式金属表面偶极子界面 Cu(100) Cu(111)

Classification of Hemifacial Microsomia Based on Bone Volume Ratio of the Healthy and Affected Sides of the Mandible:A Retrospective Self-control Experiment

在线全文

学校读者我要写书评

暂无评论

Chinese Journal of Plastic and Reconstructive Surgery 2020年第1期2卷 35-39,50页

作者： xiaohui qiu Xianxian YANG Haisong XU Zin-mar AUNG Xiaojun CHEN Yan ZHANG Gang CHAI Department of Plastic and Reconstructive Surgery Shanghai Ninth People’s HospitalShanghai JiaoTong University School of MedicineChina The College of Medical Instrument Shanghai University of Medicine&Health SciencesNo.257Zhouzhu HighwayPudong DistrictShanghaiChina Department of Plastic and Reconstructive Surgery Maternal and Child Health Care Hospital of Hainan ProvinceHaikou 570206China

Objective Hemifacial microsomia(HFM),a congenital craniofacial malformation,is characterized by unilateral mandibular *** present,the Pruzansky classification is the most common descriptive classification used clinically,which involves mandibular *** multiple classification systems have been proposed for HFM,a quantitative classification has not yet been *** study intended to propose a quantitative classification for HFMaccording to the mandibular volume on the affected *** Patients with HFM from January 2017 to January 2018 were included,and the A/U ratio(volume of the affected side/volume of the unaffected side)was *** study proposed a classification for HFM(mandibular-volume classification,MVC)according to the A/U ratio and compared the new classification system with the Pruzansky classification using consistency and correlation *** A total of 48 patients were *** results of MVC based on the A/U ratio were as follows:A/U>0.85,classified asmild;0.73-0.85,as moderate;and<0.73 assevere;the weighted kappa value of the Pruzansky and MVC classifications was 0.616(P<0.01).Conclusion The quantitative classification of HFMbased on the A/U ratio can serve asa viable evaluation index for patients withHFM and can provide a new reference index for determiningthe treatment plan.

关键词： Hemifacialmicrosomia quantitative classification mandibular volume ratio Pruzansky classification

Photodoping-Modified Charge Density Wave Phase Transition in WS_(2)/1T-TaS_(2) Heterostructure

在线全文

学校读者我要写书评

暂无评论

Chinese Physics Letters 2024年第5期41卷 144-170页

作者：王瑞丁建伟孙飞赵继民裘晓辉 Beijing Information Technology College Beijing 100015China CAS Key Laboratory of Standardization and Measurement for Nanotechnology CAS Center for Excellence in NanoscienceNational Center for Nanoscience and TechnologyBeijing 100190China Beijing National Laboratory for Condensed Matter Physics Institute of PhysicsChinese Academy of SciencesBeijing 100190China University of Chinese Academy of Sciences Beijing 100049China Max Planck Institute for Chemical Physics of Solids Dresden 01187Germany Songshan Lake Materials Laboratory Dongguan 523808China

Controlling collective electronic states hold great promise for development of innovative devices. Here, we experimentally detect the modification of the charge density wave(CDW) phase transition within a 1T-TaS_(2) layer in a WS_(2)/1T-TaS_(2) heterostructure using time-resolved ultrafast spectroscopy. Laser-induced charge transfer doping strongly suppresses the commensurate CDW phase, which results in a significant decrease in both the phase transition temperature(T_(c)) and phase transition stiffness. We interpret the phenomenon that photoinduced hole doping, when surpassing a critical threshold value of ~ 10^(18)cm^(-3), sharply decreases the phase transition energy barrier. Our results provide new insights into controlling the CDW phase transition, paving the way for optical-controlled novel devices based on CDW materials.

关键词： doping transition Transition

在线全文

学校读者我要写书评

暂无评论

试论图书馆网络书评的能动性作用

图书馆工作与研究 2015年第5期 24-28页

作者：邱晓辉山东省济宁市图书馆

传统的书评模式,已经逐渐被新兴的网络书评所取代。网络书评自有很大的优势,但是在现阶段也确实存在着种种不足和有待完善之处。这需要我们切合实际地分析研究,找出规律性的东西,制订出贴切的网评措施与步骤。

关键词：网络书评图书馆读者工作

Ir(111)表面石墨烯中缺陷的原子结构确认

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

高等学校化学学报 2020年第1期41卷 49-55页

作者：李世超刘梦溪裘晓辉中国科学院纳米标准与检测重点实验室中国科学院纳米科学卓越创新中心国家纳米科学中心北京100190 中国科学院大学北京100049

识别和解析石墨烯中缺陷的精确原子结构是研究不同类型缺陷的物化特性,实现石墨烯物性调控的前提,可以为在原子尺度研究石墨烯缺陷的构效关系提供重要的实验依据.本文结合扫描隧道显微镜(STM)和原子力显微镜(AFM)确认了在Ir(111)表面生... 详细信息

识别和解析石墨烯中缺陷的精确原子结构是研究不同类型缺陷的物化特性,实现石墨烯物性调控的前提,可以为在原子尺度研究石墨烯缺陷的构效关系提供重要的实验依据.本文结合扫描隧道显微镜(STM)和原子力显微镜(AFM)确认了在Ir(111)表面生长的石墨烯中自发形成的缺陷,以及通过离子轰击方法在石墨烯中引入的多种缺陷结构,包括单空位缺陷、非六元环拓扑结构以及石墨烯层下的基底缺陷.

关键词：扫描隧道显微镜 qPlus原子力显微镜石墨烯缺陷空位铱(111)表面

在线全文

学校读者我要写书评

暂无评论

论服务主导型数字图书馆

图书馆学研究 2009年第4期 43-45页

作者：仇晓惠武汉大学信息管理学院2008级硕士研究生

根据数字图书馆建设的基点、体系形成和所解决的关键任务等,数字图书馆计划和项目大致可分为:资源主导型数字图书馆、技术主导型数字图书馆、服务主导性数字图书馆。就目前数字图书馆的这三种研究类型,作者认为为用户服务是数字图书馆... 详细信息

根据数字图书馆建设的基点、体系形成和所解决的关键任务等,数字图书馆计划和项目大致可分为:资源主导型数字图书馆、技术主导型数字图书馆、服务主导性数字图书馆。就目前数字图书馆的这三种研究类型,作者认为为用户服务是数字图书馆的根本任务,应当坚持数字图书馆发展的人文主义价值取向,并指出服务主导型数字图书馆是未来数字图书馆的发展方向。

关键词：数字图书馆服务主导以人为本