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Nano Research 2023年第4期16卷 5880-5886页

作者： Zhengbin Tian xiaohui deng Ping He Guang-Hui Wang Key Laboratory of Biofuels Qingdao Institute of Bioenergy and Bioprocess TechnologyChinese Academy of SciencesQingdao 266101China University of Chinese Academy of Sciences 100049 BeijingChina

Monolithic catalysts play a crucial role in various catalytic applications,e.g.,chemical synthesis,energy conversion,and environmental treatment,but their catalytic efficiency is often limited by the restricted mass transfer and insufficient exposure of active ***,we present a dual-templating strategy to fabricate atomic Pt dispersed on monolithic N-doped mesoporous carbon nanowires(Pt_(1)/NMCW)with abundant super-/macropores,which,as monolithic catalyst,exhibits high catalytic performance in hydrogenation of 4-nitrophenol(4-NP).During synthesis,triblock copolymer(Pluronic F127)is employed as a primary soft template to generate the mesoporous structured carbon nanowires to improve the accessibility of Pt single sites;KCl crystallite is used as a secondary hard template to create the super-/macropores,which are beneficial for enhancing the mass transfer *** to the dual-templating strategy that creates the monolithic carbon nanowires with hierarchically porous structure,the obtained Pt_(1)/NMCW shows highly enhanced catalytic activity in 4-NP hydrogenation,outperforming its analogue synthesized without using KCl as template and being comparable to the nano-powder catalyst(i.e.,atomic Pt loaded on the Ndoped carbon nanospheres,Pt_(1)/NCS).

关键词： dual-templating strategy monolithic catalysts porous carbon nanowires Pt single atoms hydrogenation

CoxP@NiCo-LDH heteronanosheet arrays as efficient bifunctional electrocatalysts for co-generation of value-added formate and hydrogen with less-energy consumption

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Journal of Energy Chemistry 2020年第11期29卷 314-323页

作者： Mei Li xiaohui deng Yue Liang Kun Xiang Dan Wu Bin Zhao Haipeng Yang Jing-Li Luo Xian-Zhu Fu College of Materials Science and Engineering Shenzhen UniversityShenzhen 518055GuangdongChina Department of Chemical and Materials Engineering University of AlbertaEdmonton T6G 1H9AlbertaCanada

The inefficiency of water splitting is mainly due to the sluggish anodic water oxidation reaction. Replacing water oxidation with thermodynamically more favorable selective methanol oxidation reaction and developing robust bifunctional electrocatalysts are of great significance. Herein, a hierarchical heteronanostructure with Ni–Co layered double hydroxide(LDH) ultrathin nanosheets coated on cobalt phosphide nanosheets arrays(CoxP@NiCo-LDH) are fabricated and used for co-electrolysis of methanol/water to co-produce value-added formate and hydrogen with saving energy. Benefiting from the fast charge transfer introduced by phosphide nanoarrays, the synergy in nanosheets catalysts with hetero-interface,CoxP@NiCo-LDH/Ni foam(NF) exhibits superior electrocatalytic performance(10 mA cm-2@ 1.24 V and-0.10 V for methanol selective oxidation and hydrogen evolution reaction, respectively). Furthermore,CoxP@NiCo-LDH/NF-based symmetric two-electrode electrolyzer drives a current density of 10 m A cm-2 with a low cell voltage of only 1.43 V and the Faradaic efficiency towards the generation of formate and H2 are close to 100% in the tested range of current density(from 40 to 200 m A cm-2). This work highlights the positive effect of hetero-interaction in the design of more efficient eletrocatalysts and might guide the way towards facile upgrading of alcohols and energy-saving electrolytic H2 co-generation.

关键词： Cobalt phosphide Bifunctional electrocatalysts Selective methanol oxidation H2 evolution reaction Co-electrolysis

The Algorithm of Intelligent Compensation in Flexible Material Processing

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武汉理工大学学报 2006年第S1期28卷 162-166页

作者： TANG Luxin,deng xiaohui,LIU Zhiyuan (School of Information Engineering Guangdong University of Technology,Guangzhou 510006,China) School of Information Engineering Guangdong University of Technology Guangzhou 510006China

Flexible material is easy to be distorted in high speed sewing process,so it must be tracked in the process. In this paper,The mathematics model is established with computer visual measure and digital image process for distorted flexible material. By the means of optimizing initial iterative value,the distorted variable of two correlated subareas evaluated. The method based on improved steepest descent algorithm and simulation annealing algorithm is proposed. It has been proven that the evaluating the algorithm’s error and convergent speed by the method of numerical emulate is the effective approach.

关键词： distorted flexible material visual measurement correlated algorithm

Autophagy occurs within an hour of adenosine triphosphate treatment after nerve cell damage:the neuroprotective effects of adenosine triphosphate against apoptosis

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Neural Regeneration Research 2014年第17期9卷 1599-1605页

作者： Na Lu Baoying Wang xiaohui deng Honggang Zhao Yong Wang Dongliang Li Department of Physiology and Neurobiology Xinxiang Medical University Department of Human Anatomy Xinxiang Medical University Department of Laboratory Animal Center Xinxiang Medical University

After hypoxia, ischemia, or inflammatory injuries to the central nervous system, the damaged cells release a large amount of adenosine triphosphate, which may cause secondary neuronal death. Autophagy is a form of cell death that also has neuroprotective effects. Cell Counting Kit assay, monodansylcadaverine staining, flow cytometry, western blotting, and real-time PCR were used to determine the effects of exogenous adenosine triphosphate treatment at different concentrations （2, 4, 6, 8, 10 mmol/L） over time （1, 2, 3, and 6 hours） on the apoptosis and autophagy of SH-SY5Y cells. High concentrations of extracellular adenosine triphosphate induced autophagy and apoptosis of SH-SYSY cells. The enhanced autophagy first appeared, and peaked at 1 hour after treatment with adenosine triphosphate. Cell apoptosis peaked at 3 hours, and persisted through 6 hours. With prolonged exposure to the adenosine triphosphate treatment, the fraction of apoptotic cells increased. These data suggest that the SH-SY5Y neural cells initiated autophagy against apoptosis within an hour of adenosine triphosphate treatment to protect themselves against injury.

关键词： nerve regeneration neurons adenosine triphosphate SH-SY5Y cells autophagy apoptosis cell culture monodansylcadaverine flow cytometry cell viability Bcl-2 Bax Beclin 1 neuronal damage NSFC grant neural regeneration

Transcriptome analysis reveals therapeutic potential of NAMPT in protecting against abdominal aortic aneurysm in human and mouse

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Bioactive Materials 2024年第4期34卷 17-36页

作者： Yu Ouyang Yimei Hong Cong Mai Hangzhen Yang Zicong Wu Xiaoyan Gao Weiyue Zeng xiaohui deng Baojuan Liu Yuelin Zhang Qingling Fu Xiaojia Huang Juli Liu Xin Li Department of Emergency Medicine Guangdong Provincial People’s Hospital(Guangdong Academy of Medical Sciences)Southern Medical UniversityGuangdong510006China School of Medicine South China University of TechnologyGuangdong510006China Otorhinolaryngology Hospital The First Affiliated HospitalSun Yat-sen University58 Zhongshan Road IIGuangzhou510006China Extracellular Vesicle Research and Clinical Translational Center The First Affiliated HospitalSun Yat-sen UniversityGuangdong510006China Medical Research Institute Guangdong Provincial People’s Hospital(Guangdong Academy of Medical Sciences)Southern Medical UniversityGuangzhou510080China Department of Emergency Medicine The Key Laboratory of Advanced Interdisciplinary StudiesThe First Affiliated Hospital of Guangzhou Medical UniversityGuangzhouGuangdong 510120China Global Health Research Center Guangdong Provincial People’s Hospital(Guangdong Academy of Medical Sciences)Southern Medical UniversityGuangzhou510080China

Abdominal Aortic Aneurysm(AAA)is a life-threatening vascular disease characterized by the weakening and ballooning of the abdominal aorta,which has no effective therapeutic approaches due to unclear molecular *** single-cell RNA sequencing,we analyzed the molecular profile of individual cells within control and AAA abdominal *** found cellular heterogeneity,with increased plasmacytoid dendritic cells and reduced endothelial cells and vascular smooth muscle cells(VSMCs)in ***-regulated genes in AAA were associated with muscle tissue development and *** controlling VSMCs aberrant switch from contractile to synthetic phenotype were significantly enriched in ***,VSMCs in AAA exhibited cell senescence and impaired oxidative *** observations were made in a mouse model of AAA induced by Angiotensin II,further affirming the relevance of our findings to human *** concurrence of gene expression changes between human and mouse highlighted the impairment of oxidative phosphorylation as a potential target for *** phosphoribosyltransferase(NAMPT,also named VISFATIN)signaling emerged as a signature event in *** was significantly downregulated in ***-extracellular vesicles(EVs)derived from mesenchymal stem cells restored NAMPT levels,and offered protection against ***,NAMPT-EVs not only repressed injuries,such as cell senescence and DNA damage,but also rescued impairments of oxidative phosphorylation in both mouse and human AAA models,suggesting NAMPT supplementation as a potential therapeutic approach for AAA *** findings shed light on the cellular heterogeneity and injuries in AAA,and offered promising therapeutic intervention for AAA treatment.

关键词： Abdominal aorta Vascular smooth muscle cells Senescence Oxidative phosphorylation Electron transport chain

Infection of wild-type mice by SARS-CoV-2 B.1.351 variant indicates a possible novel cross-species transmission route

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Signal Transduction and Targeted Therapy 2022年第1期7卷 258-269页

作者： Ting Pan Ran Chen Xin He Yaochang Yuan xiaohui deng Rong Li Haiping Yan Shumei Yan Jun Liu Yiwen Zhang Xiantao Zhang Fei Yu Mo Zhou Changwen Ke Xiancai Ma Hui Zhang Institute of Human Virology Key Laboratory of Tropical Disease Control of Ministry EducationGuangdong Engineering Research Center for Antimicrobial Agent and ImmunotechnologyZhongshan School of MedicineSun Yat-sen University510080 GuangzhouGuangdongChina Center for Infection and Immunity Study School of MedicineShenzhen Campus of Sun Yat-sen University518107 ShenzhenGuangdongChina Department of Gastroenterology The Eighth Affiliated HospitalSun Yat-sen University518033 ShenzhenGuangdongChina Sun Yat-sen University Cancer Center State Key Laboratory of Oncology in South ChinaCollaborative Innovation Center for Cancer Medicine510060 GuangzhouGuangdongChina Guangdong Provincial People's Hospital Guangdong Academy of Medical Sciences510080 GuangzhouGuangdongChina Guangdong Provincial Center for Disease Control and Prevention 511430 GuangzhouGuangdongChina National Guangzhou Laboratory Bio-Island510320 GuangzhouGuangdongChina

COVID-19 is identified as a zoonotic disease caused by SARS-CoV-2,which also can cross・transmit to many animals but not *** modifications of SARS-CoV-2 or mice enable the mice susceptible to viral *** neither is the natural situation,they are currently utilized to establish mouse infection *** we report a direct contact transmission of SARS-CoV-2 variant B.1.351 in wild-type *** SARS-CoV-2(B.1.351)re plicated efficiently and induced significant pathological changes in lungs and tracheas,accompanied by elevated proinflammatory cytokines in the lungs and ***,the receptor-binding domain(RBD)of SARS-CoV-2(B.1.351)spike protein turned to a high binding affinity to mouse angiotensin-converting enzyme 2(mACE2),allowing the mice highly susceptible to SARS-CoV-2(B.1.351)*** work suggests that SARS-CoV-2(B.1.351)expands the host range and therefore increases its transmission route without adapted *** the wild house mice live with human populations quite closely,this possible transmission route could be potentially *** addition,because SARS-CoV-2(B.1.351)is one of the major epidemic strains and the mACE2 in laboratory-used mice is naturally expressed and regulated,the SARS-CoV-2(B.1.351)/mice could be a much convenient animal model system to study COVID-19 pathogenesis and evaluate antiviral inhibitors and vaccines.

关键词： elevated utilized adapted

The Main Evaluation Indicators for the Quality of Fruit Radish

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Asian Agricultural Research 2017年第5期9卷 96-99页

作者： Weiling YUAN Lei CUI Caixia GAN xiaohui deng Zhengming QIU Economic Crop Research Institute Hubei Academy of Agricultural Sciences

The aim of this study was to establish a scientific evaluation system for fruit radish quality. 8 quality indicators were measured for23 varieties,such as Meinong,Qiaotouqing and Chunbulao. The indicators included root weight,root shape index,water content,crispness,soluble solids,crude fiber,isothiocyanate and vitamin C. These data were analyzed by variation correlation analysis,principal component analysis and system cluster analysis. 23 varieties of fruit radish were analyzed by variation correlation; 8 indicators were compressed into 6 integrated variables using principal component analysis. Finally,the main evaluation indicators of fruit radish were determined by using cluster analysis and correlation analysis. The results indicated that the range of variation coefficient was from 1. 64%-89. 99%. Water content,crispness,soluble solids,crude fiber,isothiocyanate were the important components of fruit radish quality,playing a major role in the quality. These 8indicators were closely related and relatively independent. Water content was significantly and positively correlated with crispness; soluble solids and crude fiber were significantly and negatively related to vitamin C; crispness was significantly and positively correlated with crude fiber and vitamin C. Based on the above results,4 representative indicators were used for evaluating fruit radish quality,that is water content,crispness,soluble solids,crude fiber,which could reflect the most information of fruit radish quality.

关键词： Fruit radish Quality Evaluation indicators Principal component analysis Systematic cluster analysis

Size-dependent activity of Fe-N-doped mesoporous carbon nanoparticles towards oxygen reduction reaction

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Green Carbon 2024年第2期2卷 221-230页

作者： Yilun Zhao Zhengbin Tian Wenquan Wang xiaohui deng Jo-Chi Tseng Guanghui Wang Qingdao Institute of Bioenergy and Bioprocess Technology Chinese Academy of SciencesQingdao 266101China Shandong Energy Institute Qingdao 266101China Qingdao New Energy Shandong Laboratory Qingdao 266101China University of Chinese Academy of Sciences Beijing 100049China Japan Synchrotron Radiation Research Institute Hyogo 679-5198Japan

The rational design of Fe–N–C catalysts that possess easily accessible active sites and favorable mass transfer,which are usually determined by the structure of catalyst supports,is crucial for the oxygen reduction reaction(ORR).In this study,an oleic acid-assisted soft-templating approach is developed to synthesize size-controlled nitrogen-doped carbon nanoparticles(ranging from 130 nm to 60 nm and 35 nm,respectively)that feature spiral mesopores on their surface(SMCs).Next,atomically dispersed Fe–Nx sites are fabricated on the size-tunable SMCs(Fe1/SMC-x,where x represents the SMC size)and the size-dependent activity toward ORR is *** is found that the catalytic performance of Fe1/SMCs is significantly influenced by the size of SMCs,where the Fe1/SMC-60 catalyst shows the highest ORR activity with a half-wave potential of 0.90 V *** in KOH electrolyte,indicating that the gas-liquid-solid three-phase interface on the Fe1/SMC-60 enhances the accessibility of Fe–Nx *** addition,when using Fe1/SMC-60 as the cathode catalyst in aqueous zinc-air batteries(ZABs),it delivers a higher open-circuit voltage(1.514 V),a greater power density(223 mW cm^(−2)),and a larger specific capacity/energy than Pt/C-based *** results further highlight the potential of Fe1/SMC60 for practical energy devices associated with ORR and the importance of size-controlled synthesis of SMCs.

关键词： Soft-templating approach Size-dependent activity Fe-N-C catalyst Oxygen reduction reaction Zinc-air battery

Angiotensin Ⅱ enhances the group 2 innate lymphoid cells responses via its receptor AT1a during airway inflammation

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Angiotensin Ⅱ enhances the group 2 innate lymphoid cells re...

Ammonia Volatilization from Soils Fertilized with Different Nitrogen Type and Application Method in Germination and Early Seedling Stages from the Radish Field

第十四届全国免疫学学术大会

作者： Gaoyu Liu Yingying Chen Ying Wang xiaohui deng Kai deng Zhi Yao Jie Zhou Key Laboratory of Immune Microenvironment and Disease of the Ministry of Education Department of ImmunologySchool of Basic SciencesTianjin Medical University 中山大学中山医学院中山大学附属第七医院(深圳)

Group 2 innate lymphoid cells(ILC2 s) both contribute to maintain mucosal tissue homeostasis and initiate tissue airway inflammation during allergen challenge,especially during allergic inflammation and worm *** exists crosstalk between the neuro-and epithelial-derived factors and immune cells,which plays an important role in inflammation and tissue homeostasis during allergen challenge.H owever,the detailed and fine mechanism of how epithelium-derived peptides control ILC2 s(this biological process) remains to be fully *** this study,we found that lung epithelial cells express angiotensinogen(AGT) and the components of RAS,including AGT,renin,ACE were upregulated during allergen papain challenge by using immunofluorescence staining(IF) and laser confocal imaging technology and in vivo papain-induced lung inflammation ***2 s expressed relatively higher levels of the Ang II receptor AT1 a,and colocalized with lung epithelial cells expressing *** of Ang II significantly potentiated ILC2 responses both in vivo and in vitro,which were almost completely abrogated in AT1 a-deficient *** transfer of ILC2 into immunodeficient NCG mice and mixed bone marrow chimeras experiment support that the regulation of ILC2 by Ang II was cell *** of RAS signaling by either angiotensin converting enzyme(ACE) inhibitor captopril or AT1 antagonist telmisartan clearly alleviated the severity of airway inflammation in the context of ILC2-mediated allergic *** studies showed that the regulation of ILC2 by Ang II was associated with marked changes in transcriptional profiling by SMART-seq2,and the activation of Ras-ERK and MAPK signaling pathways,and the phosphorylation of ERK1/2 in ILC2 was sig nificantly induced by AngⅡ.Importantly,the decreased of ILC2 s’ activation by telmisartan was similarly observed in humanized mice after IL-33 challenge,resulted in lesser infiltrated cells in the perib

关键词： ILC2s Ang Ⅱ Airway allergic inflammation

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Agricultural Science & Technology 2016年第4期17卷 896-899页

作者： Weiling YUAN Shangyong YUAN Feng ZHANG xiaohui deng Caixia GAN Lei CUI Qingfang WANG Institute of Economic Crop Hubei Academy of Agricultural ScienceWuhan 430070China Vegetable office of Hubei Province Wuhan 430070China 不详

Ammonia volatilization(AV) from basal fertilizer with different nitrogen(N) types and application methods was investigated by the ventilation method in germination and early seedling stages during radish growth seasons in 2014. Four N fertilizer types, urea(U), ammonium bicarbonate(AB), ammonia sulfate(AS), and controlled urea formaldehyde(CUF) were applied through 5 cm depth placement(I) and 10 cm depth placement(II). The results showed that the N fertilizer type was the main factor that caused AV loss in germination and early seedling stages from the radish field. The highest and the lowest cumulative AV losses in germination and early seedling stages from the radish fields were 33.23 and 11.21 N kg/hm^2 for the treatments of AB+I and CUF+II, respectively, accounting for 60.40 and 26.40% of the N application for each treatment. The 10 cm deep placement of N reduced AV rates and lagged the AV process, and CUF significantly reduced ammonia volatilization. The data showed that the suitable N fertilizer type and application method for basal fertilizer were CUF and deep placement, ***, fertilizing with proper N fertilizer types and methods should be the efficient measures to mitigate AV losses from the radish field and will alleviate environment problems.

关键词： Radish Ammonia volatilization Ammonium bicarbonate Urea Ammonia sulfate Controlled urea formaldehyde