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Childhood malaria in the Niger delta area of Nigeria:mothers/care givers'perception,definition and treatment practices

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Asian Pacific Journal of Tropical Medicine 2009年第3期2卷 52-58页

作者： Idogun E.Sylvester Airauhi l.u Department of Chemical Pathology University of Benin Teaching HospitalBenin City Department of Medical Microbiology Biology University of Benin Teaching HospitalBenin City

Objective:The objective of the study was to evaluate mothers/care givers perception of malaria,their treatment practices and the effects on the outcome of ***:Four hundred and sixty children were enrolled and their mothers/care givers *** children were screened for malaria parasitaemia and there after,blood specimens were obtained for biochemical and haematological evaluation from those children who met the criteria and tested positive to *** *** cell volume,electrolytes,urea, creatinine,plasma glucose,and serum bilirubin were ***:A total of 460 children were studied, 233(50.7%) males and 227(49.3%) *** malaria cases were 112(24.3%) and severe malaria 348(75.7%).Those who presented early 106(23.0%) and those who presented late 354(77.0%).Perception and definition of malaria as well as the treatment seeking behaviors vary significantly with the level of education of the mothers and care *** without formal education 68(51.9%) wrongly perceived that the etiology of malaria can only be diagnosed by native doctors compared to those with primary six education 61 (26.5%) and junior secondary education 10(10.1%).Only 43(9.3%) gave the correct dose of chloroquine syrup to their sick children,while 32(7.0%) gave at sub optimal ***:Wrong perception of malaria especially the complicated malaria and wrong treatment practices are major contributory factors to the high mortality and morbidity of malaria in *** is therefore a need for health education to correct the wrong ideas about the cause and treatment practices of malaria as part of malaria control programme.

关键词： Childhood malaria Mothers/Caregivers Perception and treatment practices Nigeria

Genome-wide identification and prediction of long noncoding RNAs in half-smooth tongue sole Cynoglossus semilaevis

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Journal of Oceanology and limnology 2020年第1期38卷 226-235页

作者： JIANG Xiaoli JING xiaohong lÜ Yan SHAN Changmin lI Jiahua Yu Yan Wu Yuyong SuN Yeying College of Pharmacy Binzhou Medical UniversityYantai 264003China College of life Science Yantai UniversityYantai 264005China

At present,the function and profile of long noncoding RNAs(lncRNAs)in half-smooth tongue soles Cynoglossus semilaevis remain poorly ***,we identified lncRNAs in the species using large-scale deep sequencing approaches.A total of 96726222 clean reads and 2497 lncRNAs were obtained from the compound *** total,1694 known lncRNAs and 803 novel lncRNAs were *** of the novel lncRNAs distributed mainly in a range of 200-3000 nt and contained 2-6 *** novel lncRNAs were selected for expression analysis by quantitative reverse transcription-polymerase chain reaction,of which lnc_770 and lnc_150 were expressed mainly in the *** study provides a valuable resource for lncRNA studies of half-smooth tongue sole and improves our understanding of the function of non-coding RNA in fish.

关键词： Cynoglossus semilaevis long noncoding RNAs(lncRNAs) expression profiles

Can we be aware of both visceral and somatic sensations via a single neuronal pathway?

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Chinese Science Bulletin 2002年第23期47卷 1940-1945页

作者： Guowei lü Qingjin li Zhuo Meng xiaohong l.u Capital.univ Med Sci Dept Neurobiol Beijing 100054 Peoples R China

Sensory information arising from somatic and visceral area is thought to be respectively transmitted to the brain by two distinct sensory neuronal systems, the somatic and visceral sensory pathway. A novel and unique spinal sensory system, the spinosolitary tract-dorsal column postsynaptic neuronal system (SST-DCPS), was physiologically and anatomically identified. The spinal neurons project to both visceral (the solitary tract nucl.us) and somatic sensory (the dorsal column nuclei) nuclei via their branched axons and receive both visceral and somatic sensory information ascending from periphery through dichotomized primary afferents and descending from their targets via their branched axons. The brain might thus be aware of both visceral and somatic sensation via a single SST-DCPS neuronal channel. The finding of SST-DCPS system, as an example, might be considered as an intersection or fuzzy set of the SST and DCPS system and the concept of dichotomy in classification of neurons and neuronal pathways

关键词： spinosolitary tract-dorsal column postsynaptic system branching/collateral projection dichotomized primary afferent somatovisceral sensory convergence spinal cord somatovisceral interaction referred pain.

Joint Statement on COVID-19

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Engineering 2021年第3期7卷 273-274页

作者： xiaohong li Jim McDonald John l.Anderson Presidents of Chinese Aeademy of Einginering(CAE)Royal Amdemy of Ergineering(RAErg) and US national Academy of Engineering(NAE)

Advances in engineering and technology have played an indispensable role in shaping social and economic development.A host of new global challenges have appeared,though,that must be addressed through engineering education,research,and *** address such challenges,the national academies of engineering of China,the united Kingdom,and the united States have jointly sponsored four Global Grand Challenges Summits(GGCS)since *** GGCS were l.unched to accelerate global engage-ment on the Grand Challenges for Engineering-14 goals for improving life on the planet-and encourage international collabo-rations to achieve them.

关键词： jointly Grand planet

Can Talent Policies Attract Population Inflows?—An Empirical Analysis Based on Spatial Panel Modeling

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Journal of Systems Science and Information 2023年第6期11卷 726-744页

作者： xiaohong JIN Jian Xu Cuihong YANG Qingyun lü School of Economics and Management University of Chinese Academy of SciencesBeijing 100049China Academy of Mathematics and Systems Sciences Chinese Academy of SciencesBeijing 100190China School of Economics and Management University of Chinese Academy of Sciences School of Business The University of WarwickCoventry CV48UWUnited Kingdom

To analyze the spatial influence mechanism of talent policy on population flow, this study compares the government work reports of 31 provinces between 2008 and 2020, and quantifies regional talent policies in nine aspects, including talent evaluation and incentives, utilizing a comprehensive, standardized, and continuous approach. Additionally, this paper develops a spatial econometric analysis model and expands on the conventional neighborhood, distance, and economic matrices by constructing a spatial weight matrix that reflects talent flow. The findings indicate that population movement exhibits spatial clustering patterns. The regional government's talent policy, primarily based on talent evaluation and incentives, positively influences population inflow. Moreover, during the implementation of talent policies, local governments demonstrate cooperative relationships. The inter-regional spillover effect between talent evaluation and talent incentives is significantly positive. In other words, a stronger local talent evaluation policy, along with robust talent incentives, encourages population inflow from neighboring provinces. However, this conclusion may vary in different regions and over time. Recently, the spatial spillover effect of population inflow and the impact of talent policies have not shown significant results. Additionally, the attractiveness of talent evaluation in the eastern region surpasses that of talent incentives, while the opposite holds true for the central and western regions. This study investigates the impact of local government talent policies on population inflow and its spatial spillover effect, offering theoretical support for intergovernmental cooperation.

关键词： talent policy population mobility spatial econometric modeling

Intensity Evolution of Zonal Shear line over the Tibetan Plateau in Summer:A Perspective of Divergent and Rotational Kinetic Energies

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Advances in Atmospheric Sciences 2022年第7期39卷 1021-1033页

作者： xiaohong BAO Xiuping YAO State Key laboratory on Severe Weather Chinese Academy of Meteorological SciencesBeijing 100081China China Meteorological Administration Training Centre Beijing 100081China

Based on the ERA5 reanalysis datasets during 1980-2019,a total of eleven zonal shear lines(ZSls)that caused heavy precipitation and lasted more than 60 hours over the Tibetan Plateau in summer are selected for composite *** decomposing the kinetic energy(K)near the ZSl into divergent and rotational kinetic energies(K_(D)and K_(R))and the kinetic energy of interaction between the divergent wind and the rotational wind(K_(R)D),the influence of the rotational and divergent winds on the evolution of the ZSl intensity is investigated from the perspective of K_(D)and K_(R).The main results are as *** ZSl is a comprehensive reflection of rotation and *** intensity evolution of ZSl is essentially synchronized with those of K,K_(R),and K_(RD)but lags behind K_(D)by about three *** enhancement of K is mainly contributed by K_(R),which is governed by the conversion from K_(D)to K_(R).Furthermore,the increase in the conversion from K_(D)to K_(R)is controlled by the geostrophic effect term Af,which is determined by the joint enhancement of the zonal rotational and meridional divergent wind components(u_(R)and v_(D)).Therefore,the joint enhancement of u_(R)and v_(D)controls the increase of the ZSl intensity,leading to increased precipitation.

关键词： zonal shear line over the Tibetan Plateau intensity evolution divergent and rotational kinetic energies joint action of the zonal rotational and meridional divergent wind components

DNA nanomachines: monitoring molecular encounter dynamics in live cell membranes

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National Science Review 2018年第3期5卷 300-301页

作者： Jiachao Xu xiaohong Fang Beijing National laboratory for Molecular Sciences Key Laboratory of Molecular Nanostructure and Nanotechnology Institute of Chemistry Chinese Academy of Sciences university of Chinese Academy of Sciences

The cell membrane features a variety of heterogeneous and dynamic compartments to regulate cell structure and *** compartments are generally classified into a relatively packed,lipidordered(lo)domain(10-200 nm)enriched in saturated lipids and cholesterol,and a more fluid,liquid-disordered(ld)domain comprising mainly unsaturated lipids[1].According to the lipid raft theory,lodomains,which selectively recruit specific lipids and proteins,serve as criti-

关键词： DNA nanomachines monitoring molecular encounter dynamics in live cell membranes

Toxicity-oriented water quality engineering

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Frontiers of Environmental Science & Engineering 2020年第5期14卷 47-54页

作者： Shengkun Dong Chenyue Yin xiaohong Chen Guangdong Engineering Technology Research Center of Water Security Regulation and Control for Southern China Guangzhou 510275China Key laboratory of Water Cycle and Water Security in Southern China of Guangdong Higher Education Institute School of Civil EngineeringSun Yat-sen UniversityGuangzhou 510275China

The fundamental goal of water quality engineering is to ensure water safety to humans and the *** water quality engineering consists of monitoring,evaluation,and control of key water quality *** approach provides some vital insights into water quality,however,most of these parameters do not account for pol.utant mixtures-a reality that terminal water users face,nor do most of these parameters have a direct connection with the human health safety of *** puts the real health-specific effects of targeted water pol.utant monitoring and engineering control in *** focus our attention to one of the original goals of water quality engineering-human health and environmental protection,we advocate here the toxicity-oriented water quality monitoring and *** article presents some of our efforts towards such ***,complementary to traditional water quality parameters,we evaluated the water toxicity using high sensitivity toxicological endpoints,and subsequently investigated the performance of some of the water treatment strategies in modulating the water ***,we implemented the toxicity concept into existing water treatment design theory to facilitate toxicity-oriented water quality control *** for the next steps are also *** hope our work will intrigue water quality scientists and engineers to improve and embrace the mixture water pol.utant and toxicological evaluation and engineering control.

关键词： Water Wastewater Mixture Toxicity Monitor Control

The mechanism of astragaloside Ⅳ promoting sciatic nerve regeneration

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Neural Regeneration Research 2013年第24期8卷 2256-2265页

作者： xiaohong Zhang Jiajun Chen School of Pharmacutical Sciences Jilin University Department of Neurology China-Japan Union Hospital Jilin University

3-O-beta-D-xylopyranosyl-6-O-beta-D-glucopyranosyl-cycloastragenol （astragaloside IV）, the main active component of the traditional Chinese medicine astragalus membranaceus, has been shown to be neuroprotective. This study investigated whether astragaloside IV could promote the repair of injured sciatic nerve. Denervated sciatic nerve of mice was subjected to anastomosis. The mice were intraperitoneally injected with 10, 5, 2.5 mg/kg astragaloside IV per day for 8 consecutive days Western blot assay and real-time PCR results demonstrated that growth-associated protein-43 ex- pression was upregulated in mouse spinal cord segments l4-6 after intervention with 10, 5, 2.5 mg/kg astragaloside IV per day in a dose-dependent manner. luxol fast blue staining and elec- trophysiological detection suggested that astragaloside IV elevated the number and diameter of myelinated nerve fibers, and simultaneously increased motor nerve conduction velocity and action potential amplitude in the sciatic nerve of mice. These results indicated that astragaloside IV con- tributed to sciatic nerve regeneration and functional recovery in mice. The mechanism underlying this effect may be associated with the upregulation of growth-associated protein-43 expression.

关键词： neural regeneration traditional Chinese medicine peripheral nerve injury astragaloside IVgrowth-associated protein-43 sciatic nerve nerve myelin sheath myelinated nerve axonsneuroregeneration