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Effect of Ginsenoside-Rb_1 on Cardiomyocyte Apoptosis after Ischemia and Reper fusion in Rats

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Journal of Huazhong University of Science and Technology(Medical Sciences) 2002年第3期22卷 212-215页

作者：关丽李维真刘正湘 Department of Cardiology People'sHospital of Luohu District Shenzhen 518001 Operating Room Xiaogan Central Hospital Xiaogan 432100 Department of Cardiology Tongji Hospital TongjiMedical College Huazhong University of Science and Technology Wuhan 430030

The effect of ginsenoside Rb 1 on cardiomyocyte apotosis after ischemia (30 min ) and reperfusion (6 h) in rats was observed. The ischemia/ reperfusion heart mo del was established by ligating left anterior descending branch of coronary arte ry in Wistar rats. The apoptotic cardiomyocytes were examined under transmission electron microscopy and counted by in situ nick end labeling (TUNEL) method and light microscopy. Results showed that (1) The apoptotic cardiomyocytes were found in ischemic regions in the ischemia/reperfusion group, but not in the sh am oper ating group under transmission electron microscopy; (2) The number of apoptotic cells were 134.45±45.61/field in the ischemia/reperfusion group, 0/field in the sham operating group and 51.65±13.71/field in the ginsenoside Rb 1 treated group. The differences were significant among the three groups ( P <0.01). It was concluded that myocardial ischemia reperfusion could induce cardiomyocyte a poptosis, and ginsenoside Rb 1 could significantly inhibit cardiomyocyte apopto sis induced by ischemia reperfusion in rats, indicating that ginsenoside Rb 1 could inhibit cardiomyocyte apoptosis induced by ischemia reperfusion, thus alleviating ischemia reperfusion injury.

关键词： ginsenoside Rb 1 ischemia/reperfusion cardi omyocyte apoptosis

The Exhumation History of North Qaidam Thrust Belt Constrained by Apatite Fission Track Thermochronology:Implication for the Evolution of the Tibetan Plateau

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Acta Geologica Sinica(English Edition) 2016年第3期90卷 870-883页

作者： CHENG xiaogan LIN Xiubin WU Lei CHEN Hanlin XIAO Ancheng GONG Junfeng ZHANG Fengqi YANG Shufeng School of Earth Sciences Zhejiang UniversityHangzhou 310027ZhejiangChina Research Center for Structures in Oil-and Gas-Bearing Basins Ministry of EducationHangzhou 310027ZhejiangChina

Determining the spatio-temporal distribution of the deformation tied to the India-Eurasian convergence and the impact of pre-existing weaknesses on the Cenozoic crustal deformation is significant for understanding how the convergence between India and Eurasia contributed to the development of the Tibetan Plateau. The exhumation history of the northeastern Tibetan Plateau was addressed in this research using a new apatite fission track （AFT） study in the North Qaidam thrust belt （NQTB）. Three granite samples collected from the Qaidam Shan pluton in the north tied to the Qaidam Shan thrust, with AFT ages clustering in the Eocene to Miocene. The other thirteen samples obtained from the Luliang Shan and Yuka plutons in the south related to the Luliang Shan thrust and they have showed predominantly the Cretaceous AFT ages. Related thermal history modeling based on grain ages and track lengths indicates rapid cooling events during the Eocene-early Oligocene and since late Miocene within the Qaidam Shan, in contrast to those in the Cretaceous and since the Oligocene-Miocene in the Luliang Shan and Yuka region. The results, combined with published the Cretaceous thermochronological ages in the Qaidam Shan region, suggest that the NQTB had undergo rapid exhumation during the accretions along the southern Asian Andean-type margin prior to the India-Eurasian collision. The Cenozoic deformation initially took place in the North Qaidam thrust belt by the Eocene, which is consistent with the recent claim that the deformation of the northeastern Tibetan Plateau initiated in the Eocene as a response to continental collision between India and Eurasia. The immediate deformation responding to the collision is tentatively attributed to the preexisting weaknesses of the lithosphere, and therefore the deformation of the northeastern Tibetan Plateau should be regarded as a boundary-condition-dependent process.

关键词： apatite fission track Qaidam Shan Luliang Shan North Qaidam thrust belt Tibetan plateau

液相剥离法制备MoTe_(2)纳米片及其对三乙胺的气敏性能

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微纳电子技术 2024年第10期61卷 160-169页

作者：李曦黄宝玉李新雷王楠李晓干大连理工大学集成电路学院辽宁大连116600

二碲化钼(MoTe_(2))材料呈现层状结构,不利于气体的吸附。为了提高MoTe_(2)基传感器的气敏性能,采用液相剥离的方法制备了二维MoTe_(2)纳米片。扫描电子显微镜(SEM)、N2吸脱附分析仪以及Raman光谱仪的表征结果证明,相比于原始的MoTe_(2... 详细信息

二碲化钼(MoTe_(2))材料呈现层状结构,不利于气体的吸附。为了提高MoTe_(2)基传感器的气敏性能,采用液相剥离的方法制备了二维MoTe_(2)纳米片。扫描电子显微镜(SEM)、N2吸脱附分析仪以及Raman光谱仪的表征结果证明,相比于原始的MoTe_(2)材料,液相剥离的MoTe_(2)纳米片具有疏松的层状结构,液相剥离材料的比表面积(2.0648m^(2)/g)比原始材料(0.3578m^(2)/g)扩大约6倍,为气体分子的吸附提供了充足的活性位点。并且,经过液相剥离操作之后的材料对三乙胺气体的响应值以及选择性显著增高,MoTe_(2)基传感器在室温下对体积分数10ppm(1ppm=1×10^(-6))三乙胺气体的响应值由26.02%提升至39%。结果表明,液相剥离的二维MoTe_(2)纳米片对于三乙胺气体的检测具有很大的应用潜力。

关键词：传感器二维材料 MoTe_(2) 液相剥离法纳米片三乙胺

Deformation geometry and timing of the Wupoer thrust belt in the NE Pamir and its tectonic implications

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Frontiers of Earth Science 2016年第4期10卷 751-760页

作者： xiaogan CHENG Hanlin CHEN Xiubin LIN Shufeng YANG Shenqiang CHEN Fenfen ZHANG Kang LI Zelin LIU School of Earth Sciences Zhejiang University Hangzhou 310027 China Research Center for Structures in Oil- and Gas-Bearing Basins Ministry of Education Hangzhou 310027 China Department of Exploration Geophysics College of Geophysics and Information Engineering China University of Petroleurn-Beijing Beijing 102249 China

The Pamir region, located to the northwest of the Tibetan Plateau, provides important information that can aid the understanding of the plateau＇s tectonic evolution. Here we present new findings on the deforma- tion geometry and timing of the Wupoer thrust belt at the northeastem margin of Pamir. Field investigations and interpretations of seismic profiles indicate that the eastern portion of the Wupoer thrust belt is dominated by an underlying foreland basin and an overlying piggy-back basin. A regional unconformity occurs between the Pliocene （N2） and the underlying Miocene （NI） or Paleogene （Pg） strata associated with two other local unconformities between Lower Pleistocene （Q1） and N2 and between Middle Pleistocene （Q2-4） and Q1 strata. Results of structural restorations suggest that compres- sional deformation was initiated during the latest Miocene to earliest Pliocene, contributing a total shortening magnitude of 48.6 km with a total shortening rate of 48.12%, most of which occurred in the period from the latest Miocene to earliest Pliocene. These results, com- bined with previous studies on the Kongur and Tarshkor- gan extensional system, suggest an interesting picture of strong piedmont compressional thrusting activity concur- rent with interorogen extensional rifting. Combining these results with previously published work on the lithospheric architecture of the Pamir, we propose that gravitational collapse drove the formation of simultaneous extensional and compressional structures with a weak, ductile middle crustal layer acting as a decollement along which both the extensional and compressional faults merged.

关键词： Pamir Kongur Wupoer gravitational collapse fold-and-thrust belt

Migration of paleo-uplift in southwestern Tarim Basin and its implications for orogenesis and reservoir development, NW China

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Petroleum Exploration and Development 2023年第1期50卷 99-110页

作者： YAN Jiakai CHEN Hanlin CHENG xiaogan CHEN Yongquan ZENG Changmin CHEN Cai WU Hongxiang School of Earth Sciences Zhejiang UniversityHangzhou 310058China Research Center for Structures in Oil and Gas Bearing Basins Ministry of EducationHangzhou 310058China Exploration and Development Research Institute of Petro China Tarim Oilfield Company Korla 841000China

Based on well horizon calibration,the typical seismic profiles in southwestern Tarim Basin were interpreted systematically,regional geological sections were established,and the regional denudation thickness of each tectonic period was *** this basis,the plane morphology maps of ancient structures of the Cambrian pre-salt dolomites in different periods were compiled,and the spatial distribution,development,evolution and migration of paleo-uplift in the late Early Paleozoic were *** the late Early Paleozoic,there existed a unified regional paleo-uplift widely distributed in southwestern Tarim Basin,which is called the southwestern Tarim ***“Tarim SW paleo-uplift”and“Hetian paleo-uplift”proposed in previous literatures are not independent,but the result of the spatio-temporal migration and evolution of the southwestern Tarim paleo-uplift identified in this *** southwestern Tarim paleo-uplift emerged at the end of Middle Ordovician,and took its initial shape with increased amplitude in the Late *** the Silurian,the southwestern Tarim paleo-uplift rose steadily and expanded rapidly to the east,incorporating Pishan-Hetian and other areas,with the structural high locating in the Pishan-Hetian *** the Devonian,the southwestern Tarim paleo-uplift began to shrink gradually,to a limited range in the Pishan-Hetian area in the southern part of the *** the Carboniferous,the southwestern Tarim paleo-uplift became an underwater uplift,that is,the paleo-uplift gradually died *** southwestern Tarim paleo-uplift belongs to the forebulge of the southwestern Tarim foreland basin in the late Early Paleozoic,and its formation and evolution are related to the early Paleozoic orogeny of the West Kunlun orogenic belt in the south of the Tarim *** migration of the southwestern Tarim paleo-uplift from the northwestern part of the southwestern Tarim Basin to the Pishan-Hetian area indicates the early Paleozoic orogenic

关键词： paleo-uplift denudation planar morphology of ancient structure spatio-temporal migration Early Paleozoic orogeny southwestern Tarim Basin

Tectonic evolution of Tethyan tectonic field, formation of Northern Margin basin and explorative perspective of natural gas in Tarim Basin

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Chinese Science Bulletin 2002年第S1期47卷 34-41页

作者： YANG Shufeng JIA Chengzao CHEN HanlinWEI Guoqi CHENG xiaogan JIA Dong XIAO Ancheng GUO Shaojie Department of Earth Science Zhejiang UniversityHangzhou 310027China PetroChina Company Limited Beijing 100724China Langfang Branch of Research Institute of Petroleum Exploration and Development PetroChinaLangfang 065007China Department of Earth Sciences Nanjing UniversityNanjing 310027China Dpartment of Geology Peking UniversityBeijing 100871China

Analyzing the characteristics of the Tethyantectonic field, the authors think that the Tethyan tectonicfield underwent three evolutional stages: closing of Pa-leo-Tethys and rifting of Neo-Tethys from early Permian tolate Triassic, subduction of Neo-Tethys and collision betweenthe Indian plate and the Eurasia plate from Jurassic to earlyof low Tertiary, and collision between the Arab plate and theEurasia plate and the A-type subduction of Indian plate fromlate of low Tertiary to the present. Combining the evolutionof the Tethyan orogenic belt with the characteristics of theNorthern Margin basin, it is suggested that the sedimentaryand tectonic characteristics and types of the Northern Mar-gin basin are controlled by the formation and evolution ofthe Tethyan orogenic belt and the ingression of Tethys. Theevolution of Northern Margin basin can be divided into threedevelopment stages: back-arc foreland basin from late Per-mian to Triassic, the back-arc fault subsidence and depres-sion from Jurassic to the early of low Tertiary, and the reac-tive foreland basin from the late of low Tertiary to the pre-sent. The Northern Margin basin in the Tethyan tectonicfield is an important region for natural gas accumulation,and the Tarim Basin is a part of this region.

关键词： Tethys Northern Margin basin tectonic evolution type of basin accumulation of natural gas.

Synthesis and Characterization of Two New Photochromic Inorganic-organic Hybrid Materials Based on Keggin-type Polyoxometalates

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Journal of Wuhan University of Technology(Materials Science) 2008年第3期23卷 367-371页

作者：库宗军 College of Chemistry and Materials Sciences Xiaogan University

Two new photochromic inorganic-organic hybrid materials formed from Keggin-type polyoxometalates（POMs） and metronidazole （C6H9N3O3, MNZ）, formulated as H3PMo12OaO-3MNZ·3H2O （1） and H3PW12O40.3MNZ·3H2O（2）, were synthesized and characterized by elemental analysis, IR spectra, electronic spectra, electron spin resonance （ESR） spectra and thermogravi-metry-differential thermal analysis （TG-DTA）. Reflectance spectra show the presence of weak intermolecular charge transfer between the organic and inorganic moieties in the solid state. The photochromic properties were studied by solid diffuse reflectance spectra and ESR spectra, and the photochromic reactions were found to exhibit first-order kinetics. TG-DTA showed that two hybrid materials have similar thermal behavior.

关键词： polyoxometalate metronidazole hybrid material photochromism kinetics

Optically induced transparency in a micro-cavity

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Light(Science & Applications) 2016年第1期5卷 831-835页

作者： Yuanlin zheng Jianfan Yang Zhenhua Shen Jianjun Cao Xianfeng Chen xiaogan Liang Wenjie Wan The State Key Laboratory of Advanced Optical Communication Systems and Networks and Collaborative Innovation Center of IFSA Department of Physics and AstronomyShanghai Jiao Tong UniversityShanghai 200240China MOE Key Laboratory for Laser Plasmas the University of Michigan-Shanghai Jiao Tong University Joint InstituteShanghai Jiao Tong UniversityShanghai 200240China Department of Mechanical Engineering University of MichiganAnn ArborMI 48109USA

Electromagnetically induced transparency has the unique ability to optically control transparency windows with low light in atomic ***,its practical applications in quantum physics and information science are limited due to rigid experimental *** we demonstrate a new mechanism of optically induced transparency in a micro-cavity by introducing a four-wave mixing gain to nonlinearly couple two separated resonances of the micro-cavity in an ambient environment.A signature Fano-like resonance was observed owing to the nonlinear interference of the two coupled ***,we show that the unidirectional gain of the four-wave mixing can lead to the remarkable effect of non-reciprocal transmission at the transparency *** induced transparency may offer a unique platform for a compact,integrated solution to all-optical and quantum information.

关键词： Fano resonance induced transparency micro-cavity non-reciprocity

Optimization of MgO/Al_2O_3 ratio for the maximization of active site densities in the Ni_2P/MgAlO catalysts for the hydrotreating reactions

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Journal of Energy Chemistry 2016年第4期25卷 571-576页

作者： Junen Wang xiaogan Wang Yamei Yuan Abdalla Shuaib Jianyi Shen Laboratory of Mesoscopic Chemistry School of Chemistry and Chemical EngineeringNanjing University College of Chemistry and Materials Science Huaibei Normal University

The Ni2P/MgAlO catalysts with different MgO/Al2O3 ratios were prepared by the phosphidation of corresponding Ni/MgAlO catalysts with triphenylphosphine in liquid phase. It was found that the MgO/Al2O3 ratio affected the Ni2P/MgAlO catalysts significantly. The Ni2P/MgAlO catalyst with the MgO/Al2O3 ratio of 3 (w/w) exhibited the highly dispersed Ni2P particles (similar to 9 nm) with the highest CO uptake (344 mu mol/g) and thus the highest activities for the hydrotreating reactions. However, based on the CO uptakes on the used catalysts, the TOF values for the hydrodesulphurization of dibenzothiophene as well as those for the hydrogenation of tetralin on all the Ni2P/MgAlO catalysts were respectively similar, indicating that the MgO/Al2O3 ratio did not affect the intrinsic activities of Ni2P supported on the MgAlO support for the hydrotreating reactions. (C) 2016 Science Press and Dalian Institute of Chemical Physics, Chinese Academy of Sciences. Published by Elsevier B.V. and Science Press. All rights reserved.

关键词： Supported Ni2P Liquid phase phosphidation Triphenylphosphine Microcalorimetric adsorption of CO Hydrotreating reactions