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Gonad traits and age structure of the sea urchin Heliocidaris crassispina in central range:a comparison with rangeextenders

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Journal of Oceanology and Limnology 2023年第5期41卷 1954-1964页

作者： Wenping FENG Daichi NAKANO Nobuyasu NAKABAYASHI Masakazu NAOKI xiaofei tian Yukio AGATSUMA Fisheries College Zhejiang Ocean UniversityZhoushan 316022China Graduate School of Agricultural Science Tohoku UniversitySendai 980-8572Japan Fukui Prefectural University Fukui 910-1195Japan Akita Prefectural Institute of Fisheries Oga 010-8570Japan

The sea urchin Heliocidaris crassispina has northern expanded in geographic range to Toga Bay,Oga Peninsula in the Sea of Japan due to the global *** demonstrate the gonad traits and age structure of *** in the central range and compare the difference with those in northern extended range,we collected 100 *** individuals from a barren off Shitsumi,Fukui(central range),in August *** growth,gonad traits(size,development and color),and sex ratio were investigated and compared with those in Toga Bay,in August 2014(extended range).The successive 2012–2016 year classes of *** indicated successive juvenile recruitment in the central range,as found in the extended *** individuals at three years old in central range were obviously larger than those in the extended range,showing large test diameter and body weight,possibly due to the higher temperature in central range than that in northern extended *** addition,a balanced sex ratio in the central range was found,in contrast to the female-skewed sex ratio found in the extended *** development was sex-and *** testicular development in the central range was not only delayed in comparison to ovarian development,but also less delayed than those in the extended range,which possibly attribute to the higher water temperature in the central range.A significantly lower male gonad index and L*(lightness)value was recorded in central ranges compared to that in extended range,possibly due to the releasement of sperm of *** in central ranges.

关键词： Heliocidaris crassispina age gonad development gonad color range extension

Effects of 3.7 T-24.5 T high magnetic fields on tumor-bearing mice

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Chinese Physics B 2018年第11期27卷 649-658页

作者： xiaofei tian Ze Wang Lei Zhang Chuanying Xi Li Pi Ziping Qi Qingyou Lu Xin Zhang High Magnetic Field Laboratory Key Laboratory of High Magnetic Field and Ion Beam Physical Biology Hefci Institutes of Physical Science Chinese Academy of Sciences Hefei 230031 China Institute of Physical Science and Information Technology Anhui University Hefei 230601 China Hefei National Laboratory for Physical Sciences at Microscale University of Science and Technology of China Hefei 230026 China Anhui Province Key Laboratory of Condensed Matter Physics at Extreme Conditions Hefei 230031 China

Since high magnetic field（MF） intensity can improve the image quality and reduce magnetic resonance imaging（MRI） acquisition time, the field intensity of MRIs has continued to increase over the past few decades. Although MRIs in most current hospitals are 0.5 T–3 T, there are preclinical studies have been carried out using 9.4 T MRI, and engineers are also putting efforts on building MRIs with even higher MFs. However, the accompanied safety issue of high-field MRIs is an emergent question to address before their clinical applications. In the meantime, the static magnetic field（SMF） has been shown to inhibit tumor growth in previous studies. Here, we investigated both the safety issue and the anti-tumor potentials of 3.7 T–24.5 T SMFs on GIST-T1 gastrointestinal stromal tumor-bearing nude mice. We followed up the mice three weeks after their exposure to high SMF and found that none of the mice died or had severe organ damage, except for slightly decreased food intake, weight gain, and liver function. Moreover, the tumor growth was inhibited by 3.7 T–24.5 T SMFs（up to ～54%）. It is interesting that the effects are more dependent on MF gradient than intensities, and for the same gradient and intensity, mice responded differently to hypogravity and hypergravity conditions. Therefore, our study not only demonstrated the safeness of high SMFs up to 24.5 T on mice but also revealed their anti-tumor potentials in the future.

关键词： static magnetic field (SMF) high magnetic field (MF) tumor magnetic field gradient

Intermittent F-actin Perturbations by Magnetic Fields Inhibit Breast Cancer Metastasis

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Research 2023年第4期2023卷 321-335页

作者： Xinmiao Ji xiaofei tian Shuang Feng Lei Zhang Junjun Wang Ruowen Guo Yiming Zhu Xin Yu Yongsen Zhang Haifeng Du Vitalii Zablotskii Xin Zhang High Magnetic Field Laboratory of CAS(CHMFL) CAS Key Laboratory of High Magnetic Field and Ion Beam Physical BiologyHFIPSHefeiAnhui 230031P.R China Institutes of Physical Science and Information Technology Anhui UniversityHefeiAnhui230601P.R.China Science Island Branch of Graduate School University of Science and Technology of ChinaHefeiAnhui 230031P.R China Institute of Physics of the Czech Academy of Sciences PragueCzech Republic International Magnetobiology Frontier Research Center Science IslandHefei 230031P.R.China.

F-actin(filamentous actin)has been shown to be sensitive to mechanical stimuli and play critical roles in cell attachment,migration,and cancer metastasis,but there are very limited ways to perturb F-actin dynamics with low cell *** field is a noninvasive and reversible physical tool that can easily penetrate cells and human ***,we show that 0.1/0.4-T 4.2-Hz moderate-intensity low-frequency rotating magnetic field-induced electric field could directly decrease F-actin formation in vitro and in vivo,which results in decreased breast cancer cell migration,invasion,and ***,lowfrequency rotating magnetic fields generated significantly different effects on F-actin in breast cancer *** cells,including F-actin number and their recovery after magnetic field *** an intermittent treatment modality,low-frequency rotating magnetic fields could significantly reduce mouse breast cancer metastasis,prolong mouse survival by 31.5 to 46.0%(P<0.0001),and improve their overall physical ***,our work demonstrates that low-frequency rotating magnetic fields not only can be used as a research tool to perturb F-actin but also can inhibit breast cancer metastasis through F-actin modulation while having minimum effects on normal cells,which reveals their potential to be developed as temporal-controlled,noninvasive,and high-penetration physical treatments for metastatic cancer.

关键词： metastasis invasion cancer

A Static Magnetic Field Improves Iron Metabolism and Prevents High-Fat-Diet/Streptozocin-Induced Diabetes

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The Innovation 2021年第1期2卷 26-37页

作者： Biao Yu Juanjuan Liu Jing Cheng Lei Zhang Chao Song xiaofei tian Yixiang Fan Yue Lv Xin Zhang High Magnetic Field Laboratory Hefei Institutes of Physical ScienceChinese Academy of SciencesHefeiAnhui 230031P.R.China Science Island Branch of Graduate School University of Science and Technology of ChinaHefeiAnhui 230036P.R.China School of Life Sciences Anhui UniversityHefeiAnhui 230601P.R.China Institutes of Physical Science and Information Technology Anhui UniversityHefeiAnhui 230601P.R.China

Type 2 diabetes(T2D)is a metabolic disorder with high prevalence and severe complications that has recently been indicated to be treatable by a combined static magnetic field(SMF)and electric *** systematically compared four types of SMFs and found that a downward SMF of100 mT could effectively reduce the development of hyperglycemia,fatty liver,weight gain,and tissue injury in high-fat-diet(HFD)/streptozocin-induced T2D mice,but not the upward *** downward SMF markedly restored the Bacteroidetes population and reversed the iron complex outer membrane receptor gene reduction in the mice gut microbiota,and reduced iron deposition in the *** also reduced the labile iron and reactive oxygen species level in pancreatic Min6 cells in vitro and prevented palmitate-induced Min6 cell number ***,this simple SMF setting could partially prevent HFD-induced T2D development and ameliorate related symptoms,which could provide a low-cost and non-invasive physical method to prevent and/or treat T2D in the future.

关键词： type 2 diabetes static magnetic field ROS iron metabolism insulin

Magnetic Fields Affect Alcoholic Liver Disease by Liver Cell Oxidative Stress and Proliferation Regulation

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Research 2023年第4期2023卷 499-514页

作者： Chao Song Hanxiao Chen Biao Yu Lei Zhang Junjun Wang Chuanlin Feng Xingxing Yang xiaofei tian Yixiang Fan Xinmiao Ji Hua Wang Can Xie Xin Zhang High Magnetic Field Laboratory CAS Key Laboratory of High Magnetic Field and Ion Beam Physical BiologyHFIPSHefeiAnhui 230031P.R.China Science Island Branch of Graduate School University of Science and Technology of ChinaHefeiAnhui 230036P.R.China Institutes of Physical Science and Information Technology Anhui UniversityHefeiAnhui 230601P.R.China Department of Oncology The First Affiliated Hospital of Anhui Medical UniversityHefeiAnhui 230022P.R.China International Magnetobiology Frontier Research Center Science IslandHefeiAnhui 230031P.R.China

It is well known that alcohol consumption leads to substantially increased free radical levels and health risks,which lacks effective treatment besides alcohol ***,we compared different static magnetic field(SMF)settings and found that a downward quasi-uniform SMF of~0.1 to 0.2 T could effectively alleviate alcohol-induced liver damage and lipid accumulation and improve hepatic *** of two different directions can reduce the inflammation,reactive oxygen species levels,and oxidative stress in the liver,while the downward SMF had more obvious ***,we found that the upward direction SMF of~0.1 to 0.2 T could inhibit DNA synthesis and regeneration in hepatocytes,which caused detrimental effects on the lifespan of"heavy drinking"*** contrast,the downward SMF prolongs survival of"heavy drinking"*** one hand,our study shows that~0.1 to 0.2 T moderate quasi-uniform SMFs with a downward direction have great promises to be developed into a physical method to reduce alcohol-induced liver damage;on the other hand,although the internationally recognized upper limit for SMF public exposure is 0.4 T,people should also pay extra attention to SMF strength,direction,and inhomogeneity that could generate harmful effects on specific severe pathological conditions.

关键词： damage alcohol downward

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科学哲学中的自然主义理论研究述评

哲学动态 2007年第2期 46-52页

作者：田小飞清华大学科学技术与社会研究中心北京100084

一自然主义的当代复兴

关键词：科学哲学 20世纪20-30年代社会认识论自然主义述评义理文艺复兴时期当代西方哲学

Discovery of a 1.0 Ma Yellow River terrace and redating of the fourth Yellow River terrace in Lanzhou area

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Progress in Natural Science:Materials International 2007年第2期17卷 197-205页

作者： PAN Baotian , SU Huai, HU Chunsheng, HU xiaofei, ZHOU tian and LI Jijun (Key Laboratory of Western China’s Environmental Systems, Ministry of Education, and Department of Geography, Lanzhou University, Lanzhou 730000, China) [a]Ministry of Eduction Key Laboratory of Western China's Environmental Systems [b]Department of Geography Lanzhou University Lanzhou China

Based on the aeolian loess sequence-stratigraphic division and paleomagnetic datings on terraces, we found that an undiscovered terrace with the age of 1.0 Ma BP lies between the Dunwashan terrace and Wuyishan terrace. This terrace recorded an intensive Yellow River incision event during that period. Results of paleomagnetic dating and optically stimulated luminescence (OSL) dating of the Wuyishan loess section and Zaoshugou loess section on the fourth Yellow River terrace (T4) show that the age of the fourth Yellow River terrace in Lanzhou area is 0.86 Ma BP rather than the previously believed 0. 6 Ma BP. This result answers a long-term question in the ge-omorphology community of whether there exists a 0. 8 Ma terrace in Lanzhou area. The discovery of the 1. 0 Ma Yellow River terrace and redating of the age of 0.6 Ma terrace in Lanzhou area provide new insights into further research on the evolution of Yellow River.

关键词： Lanzhou area Yellow River terrace dating.

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觉悟叙事:杜甫纪行诗的佛教解读

上海师范大学学报（哲学社会科学版） 2018年第1期47卷 106-113页

作者：田晓菲哈佛大学东亚系

佛教在文学中的影响具有一种普遍渗透性质。以此角度对唐代诗人杜甫著名的"秦州—同谷"组诗做出解读,这样一组常被独立阅读和欣赏的纪行诗,实则隐含了一个觉悟有情的成佛叙事。杜甫的自注把十二首单另的诗凝聚为一个有机的整体,我们按... 详细信息

佛教在文学中的影响具有一种普遍渗透性质。以此角度对唐代诗人杜甫著名的"秦州—同谷"组诗做出解读,这样一组常被独立阅读和欣赏的纪行诗,实则隐含了一个觉悟有情的成佛叙事。杜甫的自注把十二首单另的诗凝聚为一个有机的整体,我们按照作者自注所指示的那样把"秦州—同谷"诗作为"组诗"进行阅读,会发现组诗的结构只有在读者读到终篇的时候才得以真正建立,而这一结构正是诗人经历种种磨难最终修炼到觉悟有情的叙事结构。《发秦州》以对孔子的回应开篇与收尾,然而组诗却以追寻—觉悟/自我解脱—自我牺牲的佛教叙事结构贯穿始终。因此,在探讨宗教与文学之间的关系时,虽然可以进行多学科交叉的探讨,但出发点是文学研究还是宗教研究,却会为文本带来不同的观照。如果能够做出文学解读,注重诗人用诗歌形式展示和暗示(而不是直接表达言说)的意义,却反而会看到组诗的宗教精神。

关键词：佛教与文学 “秦州-同谷”组诗佛教解读觉悟叙事

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帝国的“蓝色公路”:《水经注》的空间想象

华东师范大学学报（哲学社会科学版） 2024年第1期56卷 38-56,176页

作者：田晓菲美国哈佛大学东亚语言与文明系美国波士顿02138

考察北魏郦道元(?—527)的《水经注》,可以从两个角度出发重构《水经注》的文本生态,以求阐明此巨著之意义与价值。其一将郦道元的作品置于经注传统的语境脉络中,一方面强调注经者所面临的局限,另一方面也指出注疏相对于原始文本的创造... 详细信息

考察北魏郦道元(?—527)的《水经注》,可以从两个角度出发重构《水经注》的文本生态,以求阐明此巨著之意义与价值。其一将郦道元的作品置于经注传统的语境脉络中,一方面强调注经者所面临的局限,另一方面也指出注疏相对于原始文本的创造潜力;其二,让郦道元的著作与同时代的南方山水写作进行对话,强调该著作在空间感知和空间表现方面的独特模式。由此提出,郦道元基于帝国想象,构建了一套由江河组成的基础设施体系,这套江河系统可以被视作以人工运河来佐助自然江河的中古隋唐政体的有力象征。

关键词：郦道元水经注帝国空间感知空间表现山水写作注疏