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In situ investigation of SiC powder's microwave sintering by SR-CT technique

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Science China(Technological Sciences) 2011年第6期54卷 1382-1388页

作者： LI YongCun XU Feng hu xiaofang QU HongYan MIAO Hong ZHANG Zhong XIAO TiQiao Chinese Academy Sciences Key Laboratory of Mechanical Behavior and Design of Materials University of Science and Technology of China Hefei 230026 China National Center for Nanoscience and Technology of China Beijing 100190 China Shanghai Synchrotron Radiation Facility Shanghai 201204 China

Microwave sintering is being developed as a novel technique for the preparation of dense structural ceramics,but the mature theory has not been established due to the technical difficulties.The synchrotron radiation X-ray computed tomography(SR-CT) technique was introduced for the first time into the study of microwave sintering to in-situ observe the microstructure evolution of silicon carbide(SiC) material in this paper.By applying the SR-CT technique,the reconstructed 2D and 3D images of the specimen were obtained and the double logarithm curve of mean neck size and time(Ln(x)-Ln(t)) were obtained from these reconstructed images.Various sintering phenomena including sintering neck growth during microwave treatment were observed from the reconstructed images.Furthermore,the differences in microstructure evolution and sintering kinetics between microwave and conventional sintering were analyzed based on the reconstructed images and the Ln(x)-Ln(t) curve.1) The sharp surface of grains near the contact region distinctly grew blunt and the sintering neck growth between these grains were obviously observed at the early stage.Besides,the larger particles grew faster than smaller ones.The main reason for these phenomena may be the micro-focusing effect of electric fields.2) During each of the three sintering stages,the sintering kinetics curve of double logarithm relationship between mean neck size and time shows a good linear relationship,but at the middle stage the slope of the curve increases dramatically,which is quite larger than conventional sintering.The preliminary interpretation for these extraordinary phenomena has been discussed in details.

关键词：微波烧结 CT技术碳化硅粉末 SR 双对数曲线计算机断层扫描烧结动力学结实

Analysis of secretome of breast cancer cell line with an optimized semi-shotgun method

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Nuclear Science and Techniques 2009年第5期20卷 286-291页

作者： TANG Xiaorong YAO Ling CHEN Keying hu xiaofang XU Lisa X. FAN Chunhai Key Laboratory of Systems Biomedicine （Shanghai Jiao Tong University） China Ministry of Education Shanghai 200240 China Dept. of Biomedical Engineering School of Life Science and Biotechnology Shanghai Jiao Tong University Shanghai 200240 China Med-X Research Institute Shanghai Jiao Tong University Shanghai. 200240 China Shanghai Institute of Applied Physics Chinese Academy of Sciences Shanghai 201800 China

Secretome, the totality of secreted proteins, is viewed as a promising pool of candidate cancer biomarkers. Simple and reliable methods for identifying secreted proteins are highly desired. We used an optimized semi-shotgun liquid chromatography followed by tandem mass spectrometry (LC-MS/MS) method to analyze the secretome of breast cancer cell line MDA-MB-231. A total of 464 proteins were identified. About 63% of the proteins were classified as secreted proteins, including many promising breast cancer biomarkers, which were thought to be correlated with tumorigenesis, tumor development and metastasis. These results suggest that the optimized method may be a powerful strategy for cell line secretome profiling, and can be used to find potential cancer biomarkers with great clinical significance.

关键词：乳腺癌癌细胞放射性化疗

Paracrine function amplifies pro-tumor electrochemical signal within neuron-glioma synapses

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Science China(Life Sciences) 2024年第6期67卷 1318-1320页

作者： Yan hu Peishan hu Xiaozhong Peng Key Laboratory of Birth Defects and Related Diseases of Women and Children of MOE State Key Laboratory of BiotherapyWest China Second University HospitalSichuan UniversityChengdu 610041China Guangdong Institute of Gastroenterology Department of General SurgeryGuangdong Provincial Key Laboratory of Colorectal and Pelvic Floor DiseasesThe Sixth Affiliated HospitalSun Yat-sen UniversityGuangzhou 510655China Department of Molecular Biology and Biochemistry Institute of Basic Medical SciencesMedical Primate Research CenterNeuroscience CenterChinese Academy of Medical SciencesSchool of Basic Medicine Peking Union Medical CollegeBeijing 100730China State Key Laboratory of Respiratory Health and Multimorbidity Institute of Basic Medical Sciences Chinese Academy of Medical SciencesSchool of Basic Medicine Peking Union Medical CollegeBeijing 100730China Institute of Laboratory Animal Science Chinese Academy of Medical Sciences&Peking Union Medical CollegeBeijing 100730China

Neuronal activity plays a pivotal role in various physiological processes,including tissue development,homeostasis,and adaptability.Advances in recent years have improved our understanding of neuronal activity in brain cancers,such as glioblastoma(GBM)and diffuse midline gliomas(DMG),which are among the most prevalent and lethal cancers affecting children and adults.Generally,the neurons regulate brain cancers via two routes.

关键词： glioma homeostasis function

Memristive crossbar array with applications in image processing

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Science China(Information Sciences) 2012年第2期55卷 461-472页

作者： hu xiaofang,DUAN ShuKai,WANG LiDan & LIAO XiaoFeng School of Electronics and Information Engineering,Southwest University,Chongqing 400715,China School of Electronics and Information Engineering Southwest University Chongqing China

A memristor is a kind of nonlinear resistor with memory capacity.Its resistance changes with the amount of charge or flux passing through it.As the fourth fundamental circuit element,it has huge potential applications in many fields,and has been expected to drive a revolution in circuit theory.Through numerical simulations and circuitry modeling,the basic theory and properties of memristors are analyzed,and a memristor-based crossbar array is then proposed.The array can realize storage and output for binary,grayscale and color images.A series of computer simulations demonstrates the effectiveness of the proposed scheme.Owing to the advantage of the memristive crossbar array in parallel information processing,the proposed method is expected to be used in high-speed image processing.

关键词： memristor crossbar array modeling and simulation image storage image output

中国古典小说虚构思想的发展——兼论虚构与艺术真实的关系

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江西社会科学 2022年第2期42卷 149-158,207,208页

作者：赵炎秋胡晓芳湖南师范大学文学院湖南长沙410081

在中国古典小说发展史上,先后出现了采录异闻的逸闻小说、设幻好奇的神怪小说、据史演义的历史小说、因文生事的英雄小说和据实虚构的世情小说。中国古典小说创作方式与题材类型的历史发展,彰显了小说虚构意识从尚未觉醒,到开始自觉,到... 详细信息

在中国古典小说发展史上,先后出现了采录异闻的逸闻小说、设幻好奇的神怪小说、据史演义的历史小说、因文生事的英雄小说和据实虚构的世情小说。中国古典小说创作方式与题材类型的历史发展,彰显了小说虚构意识从尚未觉醒,到开始自觉,到由隐趋显,再到趋向自由,最终臻于成熟的过程以及小说艺术真实从以虚为实,到去实向虚,到融虚入实,再到虚而近实,终至虚实如一的过程;并且,这一过程还表明,与深具“摹仿”及“再现”传统的西方古典小说相比,中国古典小说在“尚真”的历史追求中,也始终保有“尚奇”的民族特色,因而具有别样的文化意蕴和情感意味。

关键词：中国古典小说小说虚构思想艺术真实

Influencing Factors on Cardiovascular Health in China

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Journal of Geriatric Cardiology 2024年第1期21卷 4-33页

作者： Sheng-Shou hu 无 Fuwai Hospital Chinese Academy of Medical Sciences BeijingChina the Writing Committee of the Report on Cardiovascular Health and Diseases in China

The Annual Report on Cardiovascular Health and Diseases in China(2022)intricate landscape of cardiovascular health in China.This is the first section of the report,which dissects influential factors across diverse domains.The investigation identifies tobacco use as a paramount concern,portraying China as the global epicenter of tobacco consumption.Cigarette smoking,exacerbated by second-hand smoke exposure,emerges as a critical and preventable risk factor,contributing to a surge in attributable deaths over the past three decades.In the realm of dietary nutrition,the study discerns an overall improvement,yet discerns worrisome deviations,notably an escalating fat intake surpassing recommended guidelines.The shifting dietary structure reveals diminished consumption of cereals and vegetables juxtaposed with an uptick in animal foods,while excessive intake of cooking oil and salt persists,straying substantially from endorsed levels.The exploration of physical activity patterns unfolds a nuanced narrative.Varied trends are observed among students,with concerns arising from sedentary behaviors and inadequate adherence to recommended guidelines.The analysis spans a trajectory of declining physical activity in Chinese adults,coupled with an alarming surge in sedentary leisure time,ultimately linking these factors to heightened risks of cardiovascular diseases and increased adiposity.An examination of overweight and obesity trends uncovers a relentless upward trajectory,projecting substantial prevalence by 2030.Noteworthy prevalence rates underscore the imperative for targeted interventions to curtail this burgeoning health crisis,with the anticipated prevalence extending to nearly two-thirds of the adult population.Psychological factors,notably depression,constitute an integral facet of cardiovascular health.Prevalence rates among patients with coronary artery disease and acute myocardial infarction underscore the intricate interplay between mental health and cardiovascular outcomes.Additionally,persistent depressive sym

关键词： Influencing smoke linking

Unusual Single Electron Transfer Reactions between Alkenes and Iodine Electrophiles

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Chinese Journal of Chemistry 2024年第5期42卷 471-477页

作者： Zhengzhao Lou Jingyu hu Chuanfa Ni Xiu Wang Jinbo hu Key Laboratory of Organofluorine Chemistry Shanghai Institute of Organic ChemistryUniversity of Chinese Academy of SciencesChinese Academy of Sciences345 Ling Ling RoadShanghai200032 China School of Physical Science and Technology ShanghaiTech University100 Haike RoadShanghai201210 China

The electrophilic addition to an alkene with an electrophile has been widely studied and applied in organic synthesis.The organic chemistry textbook describes the classical reaction between an alkene and an iodine electrophile(such as elemental iodine and N-iodosuccinimide(NIS))as a typical ionic reaction,in which an iodonium ion is formed and then attacked by a nucleophile.However,in this article,we report a new and unusual reaction mode between an alkene and NIS;that is,a single electron transfer(SET)process occurs between these two reactants by forming an electron-donor acceptor complex.Not only does this unusual single electron transfer reaction between an alkene and NIS add fundamentally important knowledge to organic chemistry,it also provides a valuable synthetic method as the new SET reaction mode with opposite regioselectivity as compared with the traditional ionic mode.

关键词： Electrophilic addition Radical ions Reaction mechanisms Alkenes Fluorine

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中国社区养老研究主题及演变趋势分析

中共福建省委党校（福建行政学院）学报 2022年第2期 96-107页

作者：胡晓芳杨玉裳重庆大学公共管理学院

当前,社区养老成为联结居家养老与机构养老的枢纽,与国家应对快速老龄化的战略需求相吻合,并成为学界的热点。以2000—2021年CNKI数据库中CSSCI、CSCD及北大核心期刊文献为研究样本,借助文献计量方法,可视化地呈现国内社区养老研究主题... 详细信息

当前,社区养老成为联结居家养老与机构养老的枢纽,与国家应对快速老龄化的战略需求相吻合,并成为学界的热点。以2000—2021年CNKI数据库中CSSCI、CSCD及北大核心期刊文献为研究样本,借助文献计量方法,可视化地呈现国内社区养老研究主题及演变趋势。结果表明:2000—2021年我国社区养老研究主题均偏向于宏观和中观层面,主题演变轨迹呈现出“增强或减弱、聚合或分化、产生或消亡”的特点;“养老需求”和“养老模式”等主题始终贯穿研究的全过程,“互联网+养老”及“医养结合”相继成为研究的新方向;研究主题推进呈现政策导向性、现实相结合性和多元分散性等特征。总体而言,微观层面的讨论和本土化理论的提炼显得不足。

关键词：社区养老主题演变趋势聚类分析战略坐标

A Review of Contact Electrification at Diversified Interfaces and Related Applications on Triboelectric Nanogenerator

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Nano-Micro Letters 2024年第1期16卷 106-130页

作者： Jun hu Mitsumasa Iwamoto Xiangyu Chen CAS Center for Excellence in Nanoscience Beijing Institute of Nanoenergy and NanosystemsChinese Academy of SciencesBeijing 100083People’s Republic of China School of Nanoscience and Engineering University of Chinese Academy of SciencesBeijing 100049People’s Republic of China Department of Physical Electronics Tokyo Institute of Technology2‑12‑1 S3‑33 O‑OkayamaMeguro‑KuTokyo 152‑8552Japan

The triboelectric nanogenerator(TENG)can effectively collect energy based on contact electrification(CE)at diverse interfaces,including solid–solid,liquid–solid,liquid–liquid,gas–solid,and gas–liquid.This enables energy harvesting from sources such as water,wind,and sound.In this review,we provide an overview of the coexistence of electron and ion transfer in the CE process.We elucidate the diverse dominant mechanisms observed at different interfaces and emphasize the interconnectedness and complementary nature of interface studies.The review also offers a comprehensive summary of the factors influencing charge transfer and the advancements in interfacial modification techniques.Additionally,we highlight the wide range of applications stemming from the distinctive characteristics of charge transfer at various interfaces.Finally,this review elucidates the future opportunities and challenges that interface CE may encounter.We anticipate that this review can offer valuable insights for future research on interface CE and facilitate the continued development and industrialization of TENG.

关键词： Contact electrification Interfaces Triboelectric nanogenerators Diversified applications