检索结果-南通市图书馆

Live probiotic Lactobacillus johnsonu BS15 promotes growth performance and lowers fat deposition by improving lipid metabolism,intestinal development,and gut microflora in broilers

Live probiotic Lactobacillus johnsonu BS15 promotes growth p...

引用

中国畜牧兽医学会动物微生态学分会第五届第十三次全国学术研讨会

作者： Hesong Wang Xueqin Ni xiaodan qing Dong Zeng Min Luo Lei Liu Guangyao Li Kangcheng Pan Bo Jing Animal Microecology Institute College of VeterinarySichuan Agricultural University

Numerous studies have focused on the beneficial effects of probiotics in *** so,additional information should be obtained about the mechanisms by which a useful probiotic strain successfully exerts such beneficial *** this study,we evaluated the effect of the dietary supplementation of both live and disrupted Lactobacillus johnsonii(LJ) strain BS15 in broilers at different ***,growth performance,lipid metabolism,gut microbiota,intestinal development,and digestive ability of the broilers were assessed.A total of 180 one-day-old Cobb 500 chicks were randomly distributed into three *** chicks were fed diets supplemented with1×10 colony-forming units(cfu) LJ per gram of feed(LJ group);1×10 cfu disrupted LJ per gram of feed(D-LJ group);and de Man,Rogosa,and Sharpe liquid medium(control group),respectively,throughout a 42-day experimental *** results demonstrated that LJ supplementation of feed had a positive effect on the average daily gain and starter feed conversion *** addition,LJ supplementation of feed decreased serum triglyceride and low-density lipid cholesterol levels,as well as abdominal fat *** also reduced the mRNA levels of lipoprotein lipase in adipose tissue and stearoyl-CoA desaturase-1 in the *** diminished the mRNA quantities of the sterol regulatory element binding protein-1 c and fatty acid synthase,as well as increased the level of serum high-density lipid *** increased the mRNA quantities of peroxisome proliferator-activated receptor a,acyl CoA oxidase in the liver,and carnitine *** also improved the intestinal development and digestive ability mainly by increasing the villus height/crypt depth ratio in the *** probiotic increased the levels of epidermal growth factor and insulin-like growth factor-1,as well as the activities of trypsin and lipase in the jejunum and *** exerted beneficial effects on the intestinal ***,LJ marked

关键词： Lactobacillus lipid metabolism gut microbiota probiotic broiler

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

Analysis of hepatic transcriptome demonstrates altered lipid metabolism following Lactobacillus johnsonii BS15 prevention in chickens with subclinical necrotic enteritis

Analysis of hepatic transcriptome demonstrates altered lipid...

引用

中国畜牧兽医学会动物微生态学分会第五届第十三次全国学术研讨会

作者： xiaodan qing Dong Zeng Hesong Wang Xueqin Ni Jing Lai Lei Liu Abdul Khalique Kangcheng Pan Bo Jing Animal Microecology Institute College of VeterinarySichuan Agricultural University Key Laboratory of Animal Disease and Human Health of Sichuan Province

Background:Subclinical necrotic enteritis(SNE) widely outbreaks in chickens which inflicted growth-slowing,causing enormous social and economic *** better understand the molecular underpinnings of SNE on lipid metabolism and explore novel preventative strategies against SNE,we studied the regulatory mechanism of a potential probiotic,Lactobacillus johnsonii BS15 on the lipid metabolism pathways involved in chickens with ***:180 one-day-old chickens were randomly divided into three groups and arranged with basal diet(control and SNE group).Added with BS15(1×10 cfu/g) or Man Rogosa Sharpe(MRS) liquid medium for 28 *** hepatic gene expression of each group was then measured using high-throughput analysis methods(RNA-Seq).Quantitative real-time PCR(qRT-PCR) was used to detect the expression changes of the related ***:The results showed that there are eleven lipid metabolic pathways were found during the prevention of BS15 treatment in SNE chickens by RNA-Seq,including the peroxisome proliferator-activated receptor(PPAR) signaling pathway and arachidonic acid ***15 notably facilitated the expressions of fatty acid binding protein 2(FABP2),acyl-CoA synthetase bubblegum family member 1(ACSBG1),perilipin 1(PLIN1) and perilipin 2(PLIN2),which were involved in PPAR signaling pathway of SNE ***,suppression of phospholipase A2 group IVA(PLA2 G4 A) in arachidonic acid metabolism was observed in SNE chickens after BS15 *** expression patterns of FABP2,ACSBG1,PLIN1,PLIN2 and PLA24 G in qRT-PCR validation were consistent with RNA-Seq ***:These findings indicate that SNE may affect the hepatic lipid metabolism of ***,BS15 pretreatment may provide a prospective natural prophylaxis strategy against SNE through improving the PPAR signaling pathway and arachidonic acid metabolism.

关键词： Lactobacillus johnsonii Subclinical necrotic enteritis Hepatic transcriptome Lipid metabolism pathways

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

Probiotic enhanced intestinal immunity in broilers against subclinical necrotic enteritis

Probiotic enhanced intestinal immunity in broilers against s...

引用

中国畜牧兽医学会动物微生态学分会第五届第十三次全国学术研讨会

作者： Jinge Xin Hesong Wang Xueqin Ni xiaodan qing Lei Liu Jing Lai Abdul Khalique Guangyao Li Kangcheng Pan Bo Jing Dong Zeng Animal Microecology Institute College of VeterinarySichuan Agricultural University

Along with banning of antibiotics,necrotic enteritis(NE),especially subclinical NE(SNE) whereby no clinical signs are present in chicks,has become one of the most threatening problems in poultry ***,increasing attention has been focused on research and application of effective probiotic strains,as an alternative to antibiotics,to prevent SNE in *** the present study,we evaluated the effects of Lactobacillus johnsonii BS15 on prevention of SNE in ***,assessment determined growth performance and indexes related to intestinal mucosal immunity in the ileum and cecal tonsil of broilers.A total of 300 one-day-old Cobb 500 chicks were randomly distributed into the following five groups:control group(fed with basal diet + de Man,Rogosa,and Sharpe liquid medium[normal diet]),SNE group(normal diet),BS15 group(basal diet + 1 × 10 colony-forming units BS15/g as fed[BS15 diet]),treatment group(normal diet[days 1-28]+ BS15 diet[days 29-42]),and prevention group(BS15 diet[days 1-28]+ normal diet[days 29-42]) throughout a 42-day experimental *** infection was treated for all chicks in the SNE,BS15,treatment,and prevention *** present results demonstrated that BS15 supplementation of feeds in BS15 and prevention groups exerted a positive effect on preventing negative influences on growth performance;these negative influences included low body weight gain and increased feed conversion ratio caused by *** no changes were detected in all determined indexes in cecal tonsils,BS15-treated broilers were free from SNE-caused damage in villi in the ***15 inhibited SNE-caused decrease in immunoglobulins in the *** the lamina propria of ileum,T-cell subsets of lymphocytes influenced by SNE were also controlled by ***15 affected antioxidant abilities of the ileum and controlled SNE-induced mitochondrion-mediated apoptosis by positively changing contents and/or mRNA expression levels of apoptosis-related ***

关键词： Subclinical necrotic enteritis Lactobacillus johnsonii intestinal immunity probiotic broiler

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

肠道菌群与大脑相互作用的研究进展

引用

中国微生态学杂志 2017年第9期29卷 1097-1102页

作者：向敏卿小丹刘磊曾东倪学勤雅安市第四人民医院检验科四川雅安625014 四川农业大学动物医学院动物微生态研究中心四川成都611130

定植于宿主肠道中的微生物参与了宿主多种生理功能以及相关疾病的发生。一个新的医学研究热点在近年内逐渐被关注,肠道菌群可通过主要由神经—内分泌介导的肠—脑轴(gut-brain axis,GBA)与大脑进行双向式交流。GBA不仅实现了肠道菌群对... 详细信息

定植于宿主肠道中的微生物参与了宿主多种生理功能以及相关疾病的发生。一个新的医学研究热点在近年内逐渐被关注,肠道菌群可通过主要由神经—内分泌介导的肠—脑轴(gut-brain axis,GBA)与大脑进行双向式交流。GBA不仅实现了肠道菌群对大脑发育和功能的影响,也促使大脑对肠道菌群结构和多样性的改变成为可能。本文旨在对肠道菌群与大脑相互作用的研究进展作一综述,以期为肠道和大脑功能领域的研究以及重要相关疾病的治疗策略提供理论依据。

关键词：肠道菌群肠-脑轴功能性胃肠疾病

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

小儿消积止咳口服液联合阿奇霉素治疗小儿支原体肺炎

引用

辽宁中医杂志 2018年第3期45卷 551-553页

作者：韩晓虹陆晓丹符青海南省中医院儿科

目的：探索小儿消积止咳口服液联合阿奇霉素治疗小儿支原体肺炎的临床疗效以及安全性。方法：随机选取2013年2月—2015年12月在本院进行诊治的100例支原体肺炎患儿分为对照组和观察组各50例,收集所有患儿的临床资料,进行回顾性分析。对... 详细信息

目的：探索小儿消积止咳口服液联合阿奇霉素治疗小儿支原体肺炎的临床疗效以及安全性。方法：随机选取2013年2月—2015年12月在本院进行诊治的100例支原体肺炎患儿分为对照组和观察组各50例,收集所有患儿的临床资料,进行回顾性分析。对照组和观察组所有患儿入院后均常规进行退热、止咳、化痰的治疗,对照组患儿单纯给予阿奇霉素第1日采取10 mg/kg（最大剂量不超过0.5 g）,第2、3日采取5 mg/kg（最大剂量不超过0.25 g）,静脉滴注,停用4 d,作为1个疗程。观察组患儿在对照组治疗基础上每日加服小儿消积止咳口服液小于5岁10 m L/次,5岁及5岁以上15 m L/次;每日3次,连续服用7 d为1个疗程。两组均连续治疗2个疗程。观察并比较两组患儿临床症状消失时间、免疫功能、CRP水平、住院时间、临床疗效、不良反应等。结果：观察组患儿发热消失时间、咳嗽消失时间、肺部啰音消失时间、X线片肺部病灶消失时间、住院时间显著小于对照组,观察组患儿有效率显著高于对照组,P〈0.05;治疗前两组患儿Ig M、Ig A值、血清CRP值无显著差异,P〉0.05,治疗后观察组患儿Ig M、Ig A值、血清CRP值显著低于对照组,P〈0.05;观察组中2例患儿出现胃肠道反应,2例出现皮肤过敏,1例颅内压升高出现头痛;对照组中3例患儿出现胃肠道不适,1例出现皮肤过敏,2例出现头痛。结论：小儿消积止咳口服液联合阿奇霉素治疗小儿支原体肺炎疗效显著,可缩短患儿病程,提高患儿免疫功能,改善炎症反应,同时不增加患儿不良反应的发生率。

关键词：阿奇霉素小儿消积止咳口服液小儿支原体肺炎免疫功能疗效安全性

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Bacteriostatic effect of lipopeptides from Bacillus subtilis N-2 on Pseudomonas putida using soybean meal by solid-state fermentation

引用

Marine Life Science & Technology 2020年第2期2卷 172-180页

作者： Meng Li Haijin Mou qing Kong Tan Zhang xiaodan Fu School of Food Science and Engineering Ocean University of ChinaYushan Road 5Qingdao 266003ShandongChina

Bacillus subtilis N-2 which was isolated from natto,produced lipopeptides using soybean meal as a *** work aimed to purify,identify,and determine the antibacterial mechanism of lipopeptides produced by *** *** fermented product obtained by solid-state fermentation was subjected to water extraction,acid precipitation,and methanol *** were separated and collected using a two-step ultrafiltration method and then identified by LC-MS/*** spectrometry characterization revealed the presence of four variants of iturin A that differed according to the p-amino fatty acid chain from C14 to C17 as well as the amino acid positions.A new lipopeptide(m/z 1070.3)was identified and its structure was different from the previously reported *** lipopeptides were shown to inhibit the growth of an isolate of Pseudomonas putida,a common pathogen in decaying fish,by changing membrane *** results suggest that the lipopeptides from *** N-2 could be used as a biocontrol agent in aquaculture.

关键词： Lipopeptide Solid-state fermentation Bacillus subtilis LC-MS/MS Pseudomonas putida

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

小型犬蓄脓子宫摘除对其阴道和粪便菌群结构的影响

引用

湖南农业大学学报（自然科学版） 2016年第5期42卷 528-533页

作者：曾东冯帆卿小丹倪学勤孙豪邱贤猛邹芙沁杨明月朱星星张紫媛罗显进四川农业大学动物医学院动物微生态研究中心四川成都611130 动物疫病与人类健康四川省重点实验室四川成都611130 四川成都博爱宠物医院四川成都611100

选取4只子宫蓄脓的小型犬,分别取其阴道样品和粪便样品,采用聚合酶链式反应–变性梯度凝胶电泳(PCR–DGGE)技术,回收共性及特异性条带进行克隆测序,分析小型犬蓄脓子宫摘除对其阴道及粪便菌群结构的影响。结果显示:在摘除患犬子宫的前1... 详细信息

选取4只子宫蓄脓的小型犬,分别取其阴道样品和粪便样品,采用聚合酶链式反应–变性梯度凝胶电泳(PCR–DGGE)技术,回收共性及特异性条带进行克隆测序,分析小型犬蓄脓子宫摘除对其阴道及粪便菌群结构的影响。结果显示:在摘除患犬子宫的前1天、摘除子宫后治疗第1天和第2天,患犬阴道菌群的多样性指数分别为3.22、3.35、3.05,均匀度分别为0.88、0.92、0.83,丰富度分别为25.0、28.50、21.25,均呈先增加后降低的趋势,而粪便菌群只有丰富度呈先增加后降低的趋势;大肠杆菌、假单胞菌是阴道和粪便的共同优势菌群,红球菌是共有的特异性细菌,而葡萄球菌、嗜水气单胞菌是阴道的特有细菌,不动杆菌是粪便的特有细菌。结果表明,小型犬蓄脓子宫摘除对阴道菌群结构影响较大,阴道内的大肠杆菌及假单胞菌可能源于粪便。

关键词：小型犬子宫蓄脓阴道菌群肠道菌群

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Forward a spatio-temporal trend surface for long-term groundmeasured albedo upscaling over heterogeneous land surface

引用

International Journal of Digital Earth 2018年第5期11卷 470-484页

作者： xiaodan Wu Jianguang Wen qing Xiao Dongqin You Qiang Liu Xingwen Lin State Key Laboratory of Remote Sensing Science Institute of Remote Sensing and Digital EarthChinese Academy of SciencesBeijingPeople’s Republic of China College of Resources and Environment University of Chinese Academy of SciencesBeijingPeople’s Republic of China Joint Center for Global Change Studies BeijingPeople’s Republic of China College of Global Change and Earth System Science Beijing Normal UniversityBeijingPeople’s Republic of China

Upscaling ground albedo is challenged by the serious discrepancy between the heterogeneity of land surfaces and the small number of ground-based *** ground-based measurements cannot provide sufficient information on the characteristics of surface albedo at the scale of coarse pixels over heterogeneous land *** method of overcoming this problem is to introduce high-resolution albedo imagery as ancillary information for ***,due to the low frequency of updating of high-resolution albedo maps,upscaling time series of ground-based albedo measurements is *** paper proposes a method that is based on the idea of conceptual universal scaling methodology for establishing a spatiotemporal trend surface using very few high-resolution images and time series of ground-based measurements for spatial-temporal upscaling of *** construction of the spatiotemporal trend surface incorporates the spatial information provided by auxiliary remote sensing images and the temporal information provided by long time series of ground *** approach was illustrated by upscaling ground-based fine-scale albedo measurements to a coarse scale over the core study area in *** results indicate that this method can characterize the spatiotemporal variations in surface albedo well,and the overall correlation coefficient was 0.702 during the study period.

关键词： Trend surface upscaling spatiotemporal heterogeneous albedo

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Upscaling in situ albedo for validation of coarse scale albedo product over heterogeneous surfaces

引用

International Journal of Digital Earth 2017年第6期10卷 604-622页

作者： xiaodan Wu qing Xiao Jianguang Wen Qiang Liu Dongqin You Baocheng Dou Yong Tang State Key Laboratory of Remote Sensing Science Institute of Remote Sensing and Digital EarthChinese Academy of SciencesBeijingPeople’s Republicof China College of Resourcesand Environment University of Chinese Academy of SciencesBeijingPeople’s Republic of China Joint Center for Global Change Studies BeijingPeople’s Republic of China College of Global Change and Earth System Science Beijing Normal UniversityBeijingPeople’s Republic of China

One of the essential steps for satellite albedo validation is upscaling in situ measurements to corresponding pixel scale over relatively heterogeneous land *** the multi-scale validation strategy is applicable for heterogeneous surfaces,the calibration of the high-resolution imagery during upscaling process is never perfect,and thus the upscaling results suffer from *** regression-kriging(RK)technique can compensate the calibration part by applying kriging to upscale residuals and produce more accurate upscaling *** this paper,in situ measurements and high spatial resolution albedo imagery combined with RK technique was *** method is illustrated by upscaling surface albedo from in situ measurements scale to the coarse pixel scale in the core experimental area of HiWATER,where 17 WSN nodes were deployed at heterogeneous *** upscaling results of this method were compared with the upscaling results from multi-scale *** results show that the upscaling method based on in situ measurements and high-resolution imagery combined with RK technique can capture the spatial characteristics of surface albedo ***,an attempt was made to expand this method in time ***,a preliminary validation of the Moderate Resolution Imaging Spectroradiometer albedo product was performed as the tentative application.

关键词： Upscaling albedo heterogeneous validation in situ multi-scale

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Natural Human Skin‑Inspired Wearable and Breathable Nanofiber‑based Sensors with Excellent Thermal Management Functionality

引用

Advanced Fiber Materials 2024年第6期6卷 1955-1968页

作者： Peng Wang xiaodan Li Guifen Sun Guoqing Wang qing Han Chuizhou Meng Zhonghe Wei Yang Li School of Mechanical Engineering University of JinanJinan 250022China School of Information and Control Engineering China University of Mining and TechnologyXuzhou 221116China State Key Laboratory for Reliability and Intelligence of Electrical Equipment Engineering Research Center of Ministry of Education for Intelligent Rehabilitation Device and Detection TechnologyHebei Key Laboratory of Smart Sensing and Human‑Robot InteractionSchool of Mechanical EngineeringHebei University of TechnologyTianjin 300401China Shandong Provincial Key Laboratory of Network‑Based Intelligent Computing School of Information Science and EngineeringUniversity of JinanJinan 250022China Network Information Center Department of Computer ScienceQilu University of Technology(Shandong Academy of Sciences)Jinan 250353China School of Integrated Circuits Shandong UniversityJinan 250101China

Wearable sensors have been rapidly developed for application in various human monitoring ***,the wearing comfort and thermal properties of these devices have been largely ignored,and these characteristics urgently need to be ***,we develop a wearable and breathable nanofiber-based sensor with excellent thermal management functionality based on passive heat preservation and active Joule heating *** multifunctional device consists of a micropatterned carbon nanotube(CNT)/thermoplastic polyurethane(TPU)nanofiber electrode,a microporous ionic aerogel electrolyte and a microstructured Ag/TPU nanofiber *** to the presence of a supercapacitive sensing mechanism and the appli-cation of microstructuration,the sensor shows excellent sensing performance,with a sensitivity of 24.62 ***,due to the overall porous structure and hydrophobicity of TPU,the sensor shows good breathability(62 mm/s)and water repellency,with a water contact angle of 151.2°.In addition,effective passive heat preservation is achieved by combining CNTs with high solar absorption rates(85%)as the top layer facing the outside,aerogel with a low thermal conductivity(0.063 W m-1 k-1)as the middle layer for thermal insulation,and Ag with a high infrared reflectance rate as the bottom layer facing the *** warming,this material yields a higher temperature than ***,the active Joule heat-ing effect is realized by applying current through the bottom resistive electrode,which can quickly increase the temperature to supply controlled warming on *** proposed wearable and breathable sensor with tunable thermal properties is promising for monitoring and heat therapy applications in cold environments.

关键词： Wearable sensor Breathable Personal thermal management Electrospun nanofibers Joule heating

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：