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改进整数线性规划法的农机配备研究

中国农机化学报 2024年第3期45卷 173-181页

作者：胥备刘元义于圣洁陶丽欢唐小涵郭孝琛山东理工大学农业工程与食品科学学院山东淄博255000 华能煤炭技术研究有限公司北京市100070

山东省小麦玉米规模化轮作生产下机械效能未充分发挥,存在动力机械与机具配套比低、农机动力与资金浪费问题,主流的整数线性规划农机配备法不适配山东省中小型农业新型经营主体。在对小麦玉米周年轮作全程机械化技术模式调研后,对小面... 详细信息

山东省小麦玉米规模化轮作生产下机械效能未充分发挥,存在动力机械与机具配套比低、农机动力与资金浪费问题,主流的整数线性规划农机配备法不适配山东省中小型农业新型经营主体。在对小麦玉米周年轮作全程机械化技术模式调研后,对小面积耕作时农机配备模型采用增设租赁农机服务进行改进。通过验证计算,模型优化后年成本为47 922元,相比未优化前模型成本210 392元下降77.22%;农业机械的配备量下降63.63%。

关键词：小麦-玉米轮作全程机械化技术模式优化配备农机服务

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膝关节统计学形状模型的几何外形有效性验证

医用生物力学 2024年第2期39卷 243-249页

作者：段化兵谷雪莲李晓虎周金成常逸昊王杰郭笑辰上海理工大学健康科学与工程学院上海200093

目的获取中国男性健康膝关节的解剖参数范围,并验证健康膝关节统计学形状模型(statistical shape model,SSM)在几何外形上的有效性,为基于膝关节SSM的假体设计提供依据。方法采集112例健康男性膝关节CT影像,建立三维膝关节模型,每例模... 详细信息

目的获取中国男性健康膝关节的解剖参数范围,并验证健康膝关节统计学形状模型(statistical shape model,SSM)在几何外形上的有效性,为基于膝关节SSM的假体设计提供依据。方法采集112例健康男性膝关节CT影像,建立三维膝关节模型,每例模型都单独作为目标模型,剩余模型作为训练集进行主成分分析(principal component analysis,PCA),将得到的SSM向着目标模型进行拟合预测,得到SSM拟合模型。在样本模型和SSM拟合模型上分别标记出相同的解剖测量点,并得出17个线性参数和3个角度参数。对解剖参数值采用独立样本t检验和Mann-Whitney U检验进行统计学检验,若得出的P值均大于0.05,则证明SSM在几何外形上的有效性。结果解剖参数的定性和定量对比分析的结果显示,线性参数值的平均偏差均小于6 mm,角度参数值均小于2.5°;统计学检验的结果显示所有解剖参数的P>0.05,证明膝关节SSM拟合模型与真实健康模型在几何外形上不具有统计学差异。结论获得了健康膝关节解剖参数的参考范围,并验证了膝关节SSM模型在外形上与真实健康模型具有一致性。研究结果为基于膝关节SSM的假体设计提供依据。

关键词：膝关节统计学形状模型主成分分析几何外形解剖参数

实时荧光PCR检测弯曲菌感染病例的粪便和肛拭子样本

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中国食品卫生杂志 2024年第4期36卷 389-393页

作者：邹林贾楠张萍甄博珺郭晓晨王芳冀国强闫爱霞康颖马红梅李颖北京市通州区疾病预防控制中心北京101100 北京市顺义区疾病预防控制中心北京101300

目的通过对3起弯曲菌暴发事件中粪便和肛拭子样本采用实时荧光PCR和培养法检测结果的比较,为实验室快速有效地应对此类事件奠定基础。方法收集3起弯曲菌感染暴发事件中病例的生物样本;使用过滤培养法进行弯曲菌培养检测,分别使用原始样... 详细信息

目的通过对3起弯曲菌暴发事件中粪便和肛拭子样本采用实时荧光PCR和培养法检测结果的比较,为实验室快速有效地应对此类事件奠定基础。方法收集3起弯曲菌感染暴发事件中病例的生物样本;使用过滤培养法进行弯曲菌培养检测,分别使用原始样本、增菌24 h和增菌48 h样本提取DNA进行弯曲菌实时荧光PCR检测;使用Kappa检验对实时荧光PCR检测结果和培养法结果进行一致性分析。结果原始样本、增菌24 h和增菌48 h实时荧光PCR检测灵敏度分别为90.91%、97.22%和100%,特异度分别为75.00%、84.00%和78.95%,与培养法结果一致性分析的Kappa值分别为0.643、0.813和0.785。结论实时荧光PCR检测与培养法结合使用是弯曲菌暴发事件处置的有效实验室检测方法。

关键词：弯曲菌荧光定量聚合酶链式反应培养法腹泻病例食源性致病菌

Secular trends of asthma mortality in China and the United States from 1990 to 2019

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Chinese Medical Journal 2024年第3期137卷 273-282页

作者： xiaochen Li Mingzhou guo Yang Niu Min Xie Xiansheng Liu Department of Pulmonary and Critical Care Medicine Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhanHubei 430030China NHC Key Laboratory of Respiratory Diseases WuhanHubei 430030China

Background:Asthma imposes a large healthcare burden in China and the United States(US).However,the trends of asthma mortality and the relative risk factors have not been comparatively analyzed between the *** aim of this study was to compare the mortality and risk factors between China and the ***:The deaths,and mortality rates of asthma in China and the US during 1990–2019 were obtained from the Global Burden of Disease Study *** age–period–cohort model was used to estimate these mortality rates based on a log-linear scale with additive age,period,and cohort *** population attributable fractions of risk factors for asthma were ***:In 1990–2019,the asthma mortality rate was higher in China than in the *** crude and age-standardized asthma mortality rates trended downward in both China and the US from 1990 to *** decline in mortality was more obvious in *** gap between the two countries was narrowing.A sex difference in asthma mortality was observed with higher mortality in males in China and females in the *** age effects showed that mortality increased with age in adults older than 20 years,particularly in the *** trends were generally observed in the period and cohort rate ratios in both countries,with China experiencing a more obvious *** and high body mass index(BMI)were the leading risk factors for asthma mortality in China and the US,*** attributable to occupational asthmagens and smoking decreased the most in China and the US,***:In 1990–2019,the asthma mortality rate was higher in China than in the US;however,the mortality gap has *** increased with age in *** improvements in asthma death risk with period and birth cohort were more obvious in China than in the ***,high BMI,and aging are major health problems associated with asthma *** role of occupational asthmagens in asthma mortality under

关键词： Asthma Mortality Global disease burden China the United States Age–period–cohort model

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露天矿带式输送机横向移设技术装备研究

煤矿机械 2024年第1期45卷 30-32页

作者：王玉龙刘杰刘玉和张雷冯川刘立丰郭孝琛华能伊敏煤电有限责任公司内蒙古呼伦贝尔021130 华能煤炭技术研究有限公司北京100070

露天矿移置式带式输送机移设作业期间系统要全线停产,移设作业效率会直接影响露天矿的采剥生产。通过分析露天矿连续化作业带式输送机移设要求,确定带式输送机移设系统的设计方案,并进行了结构设计和功能分析,最终设计出专门针对露天矿... 详细信息

露天矿移置式带式输送机移设作业期间系统要全线停产,移设作业效率会直接影响露天矿的采剥生产。通过分析露天矿连续化作业带式输送机移设要求,确定带式输送机移设系统的设计方案,并进行了结构设计和功能分析,最终设计出专门针对露天矿带式输送机的横向移设系统,同时完成横向移设工艺研究,可提高露天矿带式输送机移设装备水平,降低工人劳动强度及难度,缩短带式输送机横向移设周期。

关键词：横向移设带式输送机结构设计

Synergy of phosphorus vacancies and build-in electric field into NiCo/NiCoP Mott-Schottky integrated electrode for enhanced water splitting performance

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Chinese Chemical Letters 2024年第2期35卷 604-610页

作者： xiaochen Zhang Hui Xue Jing Sun Niankun guo Tianshan Song Jiawen Sun Yi-Ru Hao Qin Wang College of Chemistry and Chemical Engineering Inner Mongolia UniversityHohhot 010021China

Vacancy engineering and Mott-Schottky heterostructure can accelerate charge transfer,regulate adsorption energy of reaction intermediates,and provide additional active sites,which are regarded as valid means for improving catalytic ***,the underlying mechanism of synergistic regulation of interfacial charge transfer and optimization of electrocatalytic activity by combining vacancy and Mott-Schottky junction remains ***,the growth of a bifunctional NiCo/NiCoP Mott-Schottky electrode with abundant phosphorus vacancies on foam nickel(NF)has been synthesized through continuous phosphating and reduction *** obtained NiCo/NiCoP heterojunctions show remarkable OER and HER activities,and the overpotentials for OER and HER are as low as 117 and 60 mV at 10 mA/cm^(2) in 1 mol/L KOH,***,as both the cathode and anode of overall water splitting,the voltage of the bifunctional NiCo/NiCoP electrocatalyst is 1.44 V at 10 mA/cm^(2),which are far exceeding the benchmark commercial *** theoretical calculation results confirm that the phosphorus vacancies and build-in electric field can effectively accelerate ion and electron transfer between NiCo alloy and NiCoP semiconductor,tailor the electronic structure of the metal centers and lower the Gibbs free energy of the ***,the unique self-supported integrated structure is beneficial to facilitate the exposure of the active site,avoid catalyst shedding,thus improving the activity and structural stability of NiCo/*** study provides an avenue for the controllable synthesis and performance optimization of Mott-Schottky electrocatalysts.

关键词： Mott-Schottky Build-in electric field Phosphorus vacancies Phosphides Overall water splitting

Refractive index sensing based on a twisted nano-kirigami metasurface

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Photonics Research 2024年第2期12卷 218-225页

作者： SHUQI QIAO xiaochen ZHANG QINGHUA LIANG YANG WANG CHANG-YIN JI XIAOWEI LI LAN JIANG SHUAI FENG HONGLIAN guo JIAFANG LI School of Science Minzu University of ChinaBeijing 100081China Key Laboratory of Advanced Optoelectronic Quantum Architecture and Measurement(Ministry of Education) Beijing Key Laboratory of Nanophotonics&Ultrafine Optoelectronic Systemsand School of PhysicsBeijing Institute of TechnologyBeijing 100081China Laser Micro/Nano Fabrication Laboratory School of Mechanical EngineeringBeijing Institute of TechnologyBeijing 100081China

Plasmonic sensing technology has attracted considerable attention for high sensitivity due to the ability to effectively localize and manipulate *** this study,we demonstrate a refractive index(RI)sensing scheme based on open-loop twisted meta-molecule arrays using the versatile nano-kirigami *** sensing has the features of a small footprint,flexible control,and simple *** engineering the morphology of meta-molecules or the RI of the ambient medium,the chiral surface lattice resonances can be significantly enhanced,and the wavelength,intensity,and sign of circular dichroism(CD)can be flexibly *** the relation between the wavelength of the CD peak and the RI of the superstrate,the RI sensor achieves a sensitivity of 1133 nm/***,we analyze these chiroptical responses by performing electromagnetic multipolar decomposition and electric field *** study may serve as an ideal platform for applications of RI measurement and provide new insights into the manipulation of chiral light–matter interactions.

关键词： twisted chiral index

Laparoscopic sacrocolpopexy for treatment of pelvic organ prolapse,a prospective observation cohort with follow-up time over 7 years

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Chinese Medical Journal 2024年第12期137卷 1477-1479页

作者： Jianbin guo xiaochen Song Shuo Liang Yuan Wang Yang Ye Qianqian Gao Juan Chen Lan Zhu Department of Obstetrics and Gynecology Peking Union Medical College HospitalChinese Academy of Medical Sciences&Peking Union Medical CollegeNational Clinical Research Center for Obstetric&Gynecologic DiseasesBeijing 100730China

To the Editor:Pelvic organ prolapse(POP)is a common pelvic floor disorder in older women and is responsible for a significant decrease in health-related quality of *** the increased longevity of women,POP is becoming a major health concern.[1]Laparoscopic sacrocolpopexy(LSC)is a common mesh-based surgical approach for severe prolapse,and a high cure rate and few complications have been reported.[2]To our knowledge,the long-term durability,complications,and pelvic floor symptoms after LSC have not been fully evaluated in detail.A few studies assessed the 5-year outcome after LSC,but these reports were limited by their retrospective design,uneven follow-up time,or inconsistent outcome assessment.

关键词： prolapse pelvic Laparoscopic

基于氧化应激途径探讨人参益脉方干预血管老化作用机制

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中国中医药信息杂志 2024年第7期31卷 63-68页

作者：石丹丹宁梓淇郭晓晨张瑶瑶张元春张海燕刘美霞刘剑刚中国中医科学院西苑医院北京100091 中国中医科学院研究生院北京100700

目的观察人参益脉方对ApoE^(-/-)小鼠氧化应激及血管老化的影响,探讨其干预血管老化的作用机制。方法将40只ApoE^(-/-)小鼠随机分为模型组、西药组(瑞舒伐他汀,2.6 mg/kg)及中药低、高剂量组(人参益脉方,4.29、8.58 g/kg),每组10只,另... 详细信息

目的观察人参益脉方对ApoE^(-/-)小鼠氧化应激及血管老化的影响,探讨其干预血管老化的作用机制。方法将40只ApoE^(-/-)小鼠随机分为模型组、西药组(瑞舒伐他汀,2.6 mg/kg)及中药低、高剂量组(人参益脉方,4.29、8.58 g/kg),每组10只,另取10只C57BL/6J小鼠作为正常组。采用西式饮食饲料喂养ApoE^(-/-)小鼠建立血管老化模型,同时各给药组分别予相应药物灌胃,正常组和模型组灌胃等体积纯净水,连续12周。HE染色及Masson染色观察小鼠主动脉组织形态变化,ELISA检测血清氧化型低密度脂蛋白(ox-LDL)含量,比色法测定血清活性氧(ROS)、谷胱甘肽(GSH)、谷胱甘肽还原酶(GPX)、烟酰胺腺嘌呤二核苷酸(NAD^(+))含量,Western blot检测主动脉组织沉默信息调节因子1(SIRT1)、p21、p53、NADPH氧化酶4(NOX4)蛋白表达。结果与正常组比较,模型组小鼠主动脉可见脂质沉积,内膜及中膜明显增厚,弹性纤维减少,胶原纤维增多;血清ox-LDL、ROS含量显著升高(P<0.01),GSH、GPX、NAD^(+)含量显著降低(P<0.01);主动脉组织SIRT1蛋白表达显著降低(P<0.05),p21、p53蛋白表达显著升高(P<0.01,P<0.05)。与模型组比较,各给药组主动脉内膜可见少量脂质沉积,各层膜结构较清晰,胶原纤维减少;各给药组血清ox-LDL、ROS含量显著降低(P<0.01),GSH含量显著升高(P<0.05,P<0.01),中药低剂量组NAD^(+)含量显著升高(P<0.05);中药高剂量组主动脉组织p21、NOX4蛋白表达显著升高(P<0.05,P<0.01)。与西药组比较,中药高剂量组ROS含量显著降低(P<0.01),p53蛋白表达显著降低(P<0.05)。与中药低剂量组比较,中药高剂量组p21蛋白表达显著降低(P<0.01),NOX4蛋白表达显著升高(P<0.01)。结论人参益脉方可能通过调节氧化应激水平和相关蛋白表达减轻血管内皮损伤,从而发挥改善血管老化作用。

关键词：人参益脉方血管老化 ApoE-/-小鼠氧化应激

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