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High Power Laser Science and Engineering 2024年第1期12卷 84-98页

作者： Yujia Zhang wei Fan Jiangfeng Wang xiaochao Wang Xinghua Lu Dajie Huang Shouying Xu Yanli Zhang Mingying Sun Zhaoyang Jiao Shenlei Zhou Xiuqing Jiang Key Laboratory of High Power Laser and Physics Shanghai Institute of Optics and Fine MechanicsChinese Academy of SciencesShanghaiChina Center of Materials Science and Optoelectronics Engineering University of Chinese Academy of SciencesBeijingChina

Frequency modulation(FM)-to-amplitude modulation(AM) conversion is an important factor that affects the time±power curve of inertial confinement fusion(ICF) high-power laser facilities. This conversion can impact uniform compression and increase the risk of damage to optics. However, the dispersive grating used in the smoothing by spectral dispersion technology will introduce a temporal delay and can spatially smooth the target. The combined effect of the dispersive grating and the focusing lens is equivalent to a Gaussian low-pass filter, which is equivalent to 8 GHz bandwidth and can reduce the intensity modulation on the target to below 5% with 0.3 nm @ 3 GHz + 20 GHz spectrum phase modulation. The results play an important role in the testing and evaluating of the FM-to-AM on the final optics and the target, which is beneficial for comprehensively evaluating the load capacity of the facility and isentropic compression experiment for ICF.

关键词： dispersion grating frequency modulation-to-amplitude modulation conversion high-power laser facility inertial confinement fusion phase modulation

煤矿开采影响下岩溶地下水化学特征及演化机制研究

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干旱区资源与环境 2024年第6期38卷 120-129页

作者：常浩魏晓超魏征河北省地质矿产勘查开发局第一地质大队邯郸056000

黑龙洞泉域位于邯郸市西南部,是北方主要的岩溶泉群之一,也是重要的煤炭开采区,其地下水化学特征是影响邯郸地区水环境质量的重要因素。为充分了解煤矿开采条件下地下水化学特征及演化机制,利用多元统计分析、水文地球化学分析等方法对... 详细信息

黑龙洞泉域位于邯郸市西南部,是北方主要的岩溶泉群之一,也是重要的煤炭开采区,其地下水化学特征是影响邯郸地区水环境质量的重要因素。为充分了解煤矿开采条件下地下水化学特征及演化机制,利用多元统计分析、水文地球化学分析等方法对不同区域(西区、东区)地下水化学特征进行深入分析,并探讨控制地下水化学演化的主导因素。结果表明:研究区地下水中主要阴阳离子组分为HCO_(3)^(-)、Ca^(2+),且东区地下水主要化学组分含量普遍高于西区。西区和东区地下水化学类型主要为HCO_(3)·SO_(4)-Ca·Mg型,而东区地下水SO_(4)^(2-)含量较高,部分水样为SO_(4)·HCO_(3)-Ca、SO_(4)·HCO_(3)-Ca·Mg型。岩石风化作用是控制研究区地下水化学成分的主导因素,且以碳酸盐岩的风化溶解为主,过高的SO_(4)^(2-)含量源于含煤地层中硫化物的氧化、石膏的溶解;离子交换反应也是影响水化学成分的重要过程,且正向离子交换的强度较大;人类活动,尤其是煤矿开采、农业活动,在一定程度上也影响着研究区地下水化学演化过程。研究结果不仅为区内生活、工农业用水安全提供理论支撑,更对密集人类活动影响下北方岩溶区地下水化学成分演化研究具有重要的借鉴意义。

关键词：地下水水化学特征离子比值水文地球化学作用岩石风化

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基于随机突变的电商平台信用监管弹性研究

管理工程学报 2024年第1期38卷 266-280页

作者：危小超佘其平聂规划武汉理工大学经济学院湖北武汉430070

本文集成随机突变理论和弹性理论,探讨了电商平台信用监管的弹性测度问题。首先,构建监管部门和平台企业信用监管演化博弈模型,引入白噪声和It^o随机微分方程建立随机动力系统;进一步,结合随机突变理论,用极限概率密度函数描述系统的均... 详细信息

本文集成随机突变理论和弹性理论,探讨了电商平台信用监管的弹性测度问题。首先,构建监管部门和平台企业信用监管演化博弈模型,引入白噪声和It^o随机微分方程建立随机动力系统;进一步,结合随机突变理论,用极限概率密度函数描述系统的均衡表现,引入弹性指标定量表述系统均衡态改变前对扰动的吸收能力,仿真模拟系统参数变化对弹性的影响。研究表明:(1)监管主体从积极监管到消极监管的结构性突变源于变量组合经过分歧点集合时产生的自组织相变;(2)监管系统弹性演化过程与随机突变过程一致,突变的发生会导致监管弹性迅速改变;(3)上级政府惩罚力度对弹性影响显著,两者呈“U”形关系;在满足“突变”临界值约束下,超额收益对弹性有负向影响,监管主体协同度和公众媒体参与度对弹性有正向影响。本研究将电商平台信用监管研究拓展到弹性研究领域,为平台监管预警和政策优化提供思路;同时,为弹性理论和突变论的集成提供方法论尝试。

关键词：电商平台信用监管随机突变理论弹性

Substring-searchable attribute-based encryption and its application for IoT devices

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Digital Communications and Networks 2021年第2期7卷 277-283页

作者： Xi Sun Hao Wang Xiu Fu Hong Qin Mei Jiang Likun Xue xiaochao wei School of Information Science and Engineering Shandong Normal UniversityJinanChina Guangxi Key Laboratory of Cryptography and Information Security GuilinChina Shandong Provincial Hospital Jinan China

With the development of big data and cloud computing technology,more and more users choose to store data on cloud servers,which brings much convenience to their management and use of data,and also the risk of data leakage.A common method to prevent data leakage is to encrypt the data before uploading it,but the traditional encryption method is often not conducive to data sharing and querying.In this paper,a new kind of Attribute-Based Encryption(ABE)scheme,which is called the Sub-String Searchable ABE(SSS-ABE)scheme,is proposed for the sharing and querying of the encrypted data.In the SSS-ABE scheme,the data owner encrypts the data under an access structure,and only the data user who satisfies the access structure can query and decrypt it.The data user can make a substring query on the whole ciphertext without setting keywords in advance.In addition,the outsourcing method is also introduced to reduce the local computation of the decryption process so that the outsourcing SSS-ABE scheme can be applied to IoT devices.

关键词： Attribute-based encryption Searchable encryption Outsourcing decryption IoT divices

Suppressing fatty acid synthase by type Ⅰ interferon and chemical inhibitors as a broad spectrum anti-viral strategy against SARS-CoV-2

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Acta Pharmaceutica Sinica B 2022年第4期12卷 1624-1635页

作者： Saba R.Aliyari Amir Ali Ghaffari Olivier Pernet Kislay Parvatiyar Yao Wang Hoda Gerami Ann-Jay Tong Laurent Vergnes Armin Takallou Adel Zhang xiaochao wei Linda D.Chilin Yuntao Wu Clay F.Semenkovich Karen Reue Stephen T.Smale Benhur Lee Genhong Cheng Department of Microbiology Immunology and Molecular GeneticsUniversity of CaliforniaLos AngelesCA 90095USA EnViro International Laboratories Los AngelesCA 90077USA Department of Human Genetics David Geffen School of MedicineUniversity of CaliforniaLos AngelesCA 90095USA Division of Endocrinology Metabolism and Lipid ResearchWashington University School of MedicineSt.LouisMO 63110USA Center for Infectious Disease Research School of Systems BiologyGeorge Mason University ManassasVA 20110USA Diabetic Cardiovascular Disease Center WashingtonUniversity School of MedicineSt.LouisMO 63110USA

SARS-CoV-2 is an emerging viral pathogen and a major global public health challenge since December of 2019, with limited effective treatments throughout the pandemic.As part of the innate immune response to viral infection, type Ⅰ interferons(IFN-Ⅰ) trigger a signaling cascade that culminates in the activation of hundreds of genes, known as interferon stimulated genes(ISGs), that collectively foster an antiviral state.We report here the identification of a group of type Ⅰ interferon suppressed genes,including fatty acid synthase(FASN), which are involved in lipid metabolism.Overexpression of FASN or the addition of its downstream product, palmitate, increased viral infection while knockout or knockdown of FASN reduced infection.More importantly, pharmacological inhibitors of FASN effectively blocked infections with a broad range of viruses, including SARS-CoV-2 and its variants of concern.Thus, our studies not only suggest that downregulation of metabolic genes may present an antiviral strategy by type Ⅰ interferon, but they also introduce the potential for FASN inhibitors to have a therapeutic application in combating emerging infectious diseases such as COVID-19.

关键词： Fatty acid synthase FASN IFN-I SARS-CoV-2 COVID-19 C75

Improving corrosion resistance of Zn-5Al(wt%)alloy by microalloying with samarium

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Journal of Rare Earths 2023年第10期41卷 1636-1644,I0006页

作者： xiaochao Zhou wei Shi Song Xiang College of Materials and Metallurgy Guizhou UniversityGuiyang550025China Key Laboratory for Mechanical Behavior and Microstructure of Materials of Guizhou Province Guiyang550025China National&Local Joint Engineering Laboratory for High-Performance Metal Structure Material and Advanced Manufacturing Technology Guiyang550025China

The role of the rare earth element Sm in as-cast Zn-5AI alloy was studied in this work.A three times higher improvement than the control group on corrosion resistance was found with rare earth Sm adding(0.15 wt%).By using an electron prove micro analyzer(EPMA),focused ion beam(FIB)and scanning Kelvin probe force microscopy(SKPFM)techniques,two main mechanisms of the premium performance of the Sm adding were revealed.One was that the non-uniform nucleation and component undercooling induced by Sm adding,reduced theα-AI layer spacing thus improved the covering efficiency of the Al_(2)O_(3)film.The other was that the dissolved Sm in the Zn/Al eutectic structure modulated the electron work function thus induced the attenuation of Volta potential discrepancy.The experimental results show that when the addition of Sm is 0.15 wt%,the minimum Volta potential difference betweenα-AI andη-Zn phases is achieved,and excessive or deficient Sm addition will increase the Volta potential difference.

关键词： Zn-5Al Sm Rare earth elements SKPFM Volta potential

Identifi cation and functional analysis of phosphorylation residues of the Arabidopsis BOTRYTIS-INDUCED KINASE1

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Protein & Cell 2013年第10期4卷 771-781页

作者： Jinhua Xu xiaochao wei Limin Yan Dan Liu Yuanyuan Ma Yu Guo Chune Peng Honggang Zhou Cheng Yang Zhiyong Lou Wenqing Shui College of Life Sciences and Tianjin State Laboratory of Protein Science Nankai UniversityTianjin 300071China High-throughput Molecular Drug Discovery Center Tianjin Joint Academy of Biotechnology and MedicineTianjin 300457China Laboratory of Structural Biology and MOE Laboratory of Protein Science School of Medicine and Life SciencesTsinghua UniversityBeijing 100084China College of Pharmacy and State Key Laboratory of Medicinal Chemical Biology Nankai UniversityTianjin 300071China

Arabidopsis BOTRYTIS-INDUCED KINASE1(BIK1)is a receptor-like cytoplasmic kinase acting early in multiple signaling pathways important for plant growth and innate immunity.It is known to form a signaling complex with a cell-surface receptor FLS2 and a co-receptor kinase BAK1 to transduce signals upon perception of pathogen-asso-ciated molecular patterns(PAMPs).Although site-specifi c phosphorylation is speculated to mediate the activation and function of BIK1,few studies have been devoted to complete profiling of BIK1 phosphorylation residues.Here,we identified nineteen in vitro autophosphoryla-tion sites of BIK1 including three phosphotyrosine sites,thereby proving BIK1 is a dual-specifi city kinase for the fi rst time.The kinase activity of BIK1 substitution mutants were explicitly assessed using quantitative mass spec-trometry(MS).Thr-237,Thr-242 and Tyr-250 were found to most signifi cantly affect BIK1 activity in autophosphoryla-tion and phosphorylation of BAK1 in vitro.A structural model of BIK1 was built to further illustrate the molecular functions of specifi c phosphorylation residues.We also mapped new sites of FLS2 phosphorylation by BIK1,which are different from those by BAK1.These in vitro results could provide new hypotheses for more in-depth in vivo studies leading to deeper understanding of how phosphorylation contributes to BIK1 activation and medi-ates downstream signaling specifi city.

关键词： phosphorylation BIK1 receptor-like cytop-lasmic kinase quantitative mass spectrometry

原位合成的钛合金@CNTs粉体SPS制备TiC/Ti复合材料的微结构与性能

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材料导报 2024年第9期38卷 197-203页

作者：白云官吉小超李海庆魏敏于鹤龙张伟广东工业大学机电工程学院中国人民解放军陆军装甲兵学院装备再制造技术国防科技重点实验室佛山科学技术学院机电工程与自动化学院

以Fe/Ni为催化剂，利用等离子体增强化学气相沉积(PECVD)方法在球形钛合金微米粉体表面原位合成了碳纳米管(CNTs)包覆的钛合金(钛合金@CNTs)复合粉末。以钛合金@CNTs粉体为原料，利用放电等离子体烧结(SPS)工艺制备了原位TiC与CNTs增强T... 详细信息

以Fe/Ni为催化剂，利用等离子体增强化学气相沉积(PECVD)方法在球形钛合金微米粉体表面原位合成了碳纳米管(CNTs)包覆的钛合金(钛合金@CNTs)复合粉末。以钛合金@CNTs粉体为原料，利用放电等离子体烧结(SPS)工艺制备了原位TiC与CNTs增强Ti基复合材料，采用扫描电镜(SEM)、透射电镜(TEM)、拉曼光谱仪、X射线衍射仪、电子探针、纳米压痕等对复合粉体及烧结复合材料的微观结构、物相成分及力学性能进行了表征分析。在此基础上探讨了催化剂前驱体含量、生长时间等对低温原位CNTs生长机理的影响，以及复合粉体烧结反应对复合材料组织结构的形成以及CNTs与Ti基体反应原位形成TiC的机理。结果表明，原位形成的TiC主要受CNTs的结晶度与SPS温度所影响。

关键词：碳纳米管原位合成钛基复合材料微结构力学性能

SiC/SiC复合编织管的抗热冲击性能与失效机理研究

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应用力学学报 2024年第2期41卷 288-296页

作者：胡庆宽许琦鹏万志慧杨保建周为晋小超河南航天精工制造有限公司河南省紧固连接技术重点实验室信阳464000 西安交通大学航天航空学院极端环境与防护技术联合研究中心西安710049

以二维二轴编织的SiC/SiC复合编织管为研究对象,研究其抗热冲击性能及失效机理。自主搭建了基于石英灯辐照加热的循环热冲击试验平台,基于该平台开展了SiC/SiC复合编织管的循环热冲击试验考核,并对循环热冲击后的复合编织管进行了径向... 详细信息

以二维二轴编织的SiC/SiC复合编织管为研究对象,研究其抗热冲击性能及失效机理。自主搭建了基于石英灯辐照加热的循环热冲击试验平台,基于该平台开展了SiC/SiC复合编织管的循环热冲击试验考核,并对循环热冲击后的复合编织管进行了径向压缩测试,探究了复合编织管力学性能与破坏机理,拟合得到了热冲击强度退化经验公式。研究结果表明,搭建的循环热冲击试验平台能够模拟快速升降温的实际服役环境,最高升温、降温速率在试验过程中分别可达约40、60℃/s。随着热冲击循环次数的增加,SiC/SiC复合编织管环向拉伸强度下降,且降幅随之增大。热冲击产生的热应力导致纤维周围的基体产生微裂纹,弱化了纤维束与基体之间的连接,这是复合编织管强度降低的原因之一。拟合的强度退化经验公式能够准确描述强度退化规律,可以满足工程应用需求。

关键词：陶瓷基复合材料 SiC/SiC复合编织管石英灯辐照加热热冲击失效机理

NEMV技术在陈家山煤矿采空区探查中的应用

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陕西煤炭 2024年第1期43卷 107-111页

作者：黄伟蔡小超郑丽娟陕煤集团铜川矿业陈家山煤矿陕西铜川727102 陕西浩兴坤达新能源科技有限公司陕西西安710000

陈家山煤矿主采侏罗系延安组4^(-2)煤层,矿井自然条件复杂,煤、油、气共存,水、火、瓦斯、煤尘、顶板灾害俱全。该矿东南边界浅部4^(-2)煤层露头线附近分布较多小煤窑,使煤矿安全生产存在安全隐患;同时由于该区域地表山高坡陡,植被茂密... 详细信息

陈家山煤矿主采侏罗系延安组4^(-2)煤层,矿井自然条件复杂,煤、油、气共存,水、火、瓦斯、煤尘、顶板灾害俱全。该矿东南边界浅部4^(-2)煤层露头线附近分布较多小煤窑,使煤矿安全生产存在安全隐患;同时由于该区域地表山高坡陡,植被茂密,无法采用传统勘探技术进行探测。在此背景下,使用基于应力-自然电磁脉冲的NEMV勘探技术对该区域进行勘探,该技术可采用无人机进行数据采集,不受地面条件影响,能够准确查明煤层赋存、地质构造形态,并对采空区、积水区等水文条件不清的区域进行精细探查。通过煤层应力系数平面图中异常区分布进行划分,在研究区内共发现该矿采空区2处,小煤窑盗采区2处,有效解决了煤矿开采中的实际问题。

关键词： NEMV勘探技术陈家山煤矿应力异常采空区小煤窑盗采