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不同酚类成分及其组合对*** PAO1的抑制效果研究

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茶叶通讯 2024年第1期51卷 85-90页

作者：刁春华杨秀芳涂云飞宋鹏鹏左小博苏小琴孔俊豪中华全国供销合作总社杭州茶叶研究所/浙江省茶资源跨界应用技术重点实验室浙江杭州310016

为研究茶叶酚类成分及其复方对*** PAO1的体外抑制作用,筛选出用药量最低的最佳抑菌组方,采用倍比稀释法结合刃天青显色测定5种酚类成分对*** PAO1的最小抑菌浓度(MIC),并采用响应面法研究对*** PAO1具有较强抑制作用的最佳配伍。结果表... 详细信息

为研究茶叶酚类成分及其复方对*** PAO1的体外抑制作用,筛选出用药量最低的最佳抑菌组方,采用倍比稀释法结合刃天青显色测定5种酚类成分对*** PAO1的最小抑菌浓度(MIC),并采用响应面法研究对*** PAO1具有较强抑制作用的最佳配伍。结果表明5种酚类成分对*** PAO1均有不同程度的抑制作用,5种茶叶活性成分对*** PAO1的抑菌性大小为:EGCG>TF60=ECG>EGC>EC。响应面分析结果表明,EGCG、EGC、ECG、TF60这4种酚类成分以1.0∶4.0∶4.81∶4.0的比例配伍时对*** PAO1具有最佳抑菌效果。

关键词：茶叶酚类成分铜绿假单胞菌抑菌活性

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Brain Functional Network Generation Using Distribution-Regularized Adversarial Graph Autoencoder with Transformer for Dementia Diagnosis

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Computer Modeling in Engineering & Sciences 2023年第12期137卷 2129-2147页

作者： Qiankun zuo Junhua Hu Yudong Zhang Junren Pan Changhong Jing Xuhang Chen xiaobo Meng Jin Hong School of Information Engineering Hubei University of EconomicsWuhan430205China State Key Laboratory of Simulation and Regulation of Water Cycle in River Basin China Institute of Water Resources and Hydropower ResearchBeijing100038China School of Computing and Mathematic Sciences University of LeicesterLeicesterLE17RHUK Shenzhen Institutes of Advanced Technology Chinese Academy of SciencesShenzhen518055China Faculty of Science and Technology University of MacaoMacao999078China School of Geophysics Chengdu University of TechnologyChengdu610059China Laboratory of Artificial Intelligence and 3D Technologies for Cardiovascular Diseases Guangdong Provincial Key Laboratory of South China Structural Heart DiseaseGuangdong Provincial People’s Hospital(Guangdong Academy of Medical Sciences)Southern Medical UniversityGuangzhou519041China Medical Research Institute Guangdong Provincial People’s Hospital(Guangdong Academy of Medical Sciences)Southern Medical UniversityGuangzhou519041China

The topological connectivity information derived from the brain functional network can bring new insights for diagnosing and analyzing dementia *** brain functional network is suitable to bridge the correlation between abnormal connectivities and dementia ***,it is challenging to access considerable amounts of brain functional network data,which hinders the widespread application of data-driven models in dementia *** this study,a novel distribution-regularized adversarial graph auto-Encoder(DAGAE)with transformer is proposed to generate new fake brain functional networks to augment the brain functional network dataset,improving the dementia diagnosis accuracy of data-driven ***,the label distribution is estimated to regularize the latent space learned by the graph encoder,which canmake the learning process stable and the learned representation ***,the transformer generator is devised to map the node representations into node-to-node connections by exploring the long-term dependence of highly-correlated distant brain *** typical topological properties and discriminative features can be preserved ***,the generated brain functional networks improve the prediction performance using different classifiers,which can be applied to analyze other cognitive *** on the Alzheimer’s Disease Neuroimaging Initiative(ADNI)dataset demonstrate that the proposed model can generate good brain functional *** classification results show adding generated data can achieve the best accuracy value of 85.33%,sensitivity value of 84.00%,specificity value of 86.67%.The proposed model also achieves superior performance compared with other related ***,the proposedmodel effectively improves cognitive disease diagnosis by generating diverse brain functional networks.

关键词： Adversarial graph encoder label distribution generative transformer functional brain connectivity graph convolutional network dementia

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杵针治疗眩晕风痰上扰证临床观察

光明中医 2023年第6期38卷 1126-1128页

作者：代志敏税梦琳李丽潘霞高春梅左小波程梦瑶西南医科大学附属中医医院综合内科四川泸州646000

目的研究杵针疗法在眩晕风痰上扰患者中的临床应用效果。方法2019年11月—2021年7月在综合内科住院的60例眩晕风痰上扰患者,随机分为对照组和观察组各30例。对照组采用常规治疗护理方法,观察组在常规治疗护理的基础上配合杵针疗法。结... 详细信息

目的研究杵针疗法在眩晕风痰上扰患者中的临床应用效果。方法2019年11月—2021年7月在综合内科住院的60例眩晕风痰上扰患者,随机分为对照组和观察组各30例。对照组采用常规治疗护理方法,观察组在常规治疗护理的基础上配合杵针疗法。结果观察组临床总有效率疗效、患者生活质量评分(QOL)均高于对照组,眩晕症状分级评分(DARS)低于对照组,差异有统计学意义(P<0.05)。结论杵针疗法可以缓解眩晕风痰上扰患者眩晕及伴随的症状,提高患者的生活质量,值得临床推广运用。

关键词：杵针疗法眩晕风痰上扰证

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藤茶功能成分研究及开发应用进展

中国野生植物资源 2023年第12期42卷 79-83页

作者：刁春华杨秀芳左小博涂云飞苏小琴宋鹏鹏孔俊豪中华全国供销合作总社杭州茶叶研究所浙江杭州310016 浙江省茶资源跨界应用技术重点实验室浙江杭州310016

藤茶是葡萄科蛇葡萄属显齿蛇葡萄的嫩茎叶,是我国民间广为流传的民族特色饮用植物,因其富含黄酮类、多酚类化合物受到了广泛的研究和关注。近几年来,学者们对其药理功效方面的研究不断深入。本文根据近年来国内外的最新研究进展,对藤茶... 详细信息

藤茶是葡萄科蛇葡萄属显齿蛇葡萄的嫩茎叶,是我国民间广为流传的民族特色饮用植物,因其富含黄酮类、多酚类化合物受到了广泛的研究和关注。近几年来,学者们对其药理功效方面的研究不断深入。本文根据近年来国内外的最新研究进展,对藤茶主要物质基础、生物活性、开发利用等进行了梳理归纳,以期为藤茶及其活性成分的应用技术研究、新产品开发提供借鉴与参考。

关键词：藤茶化学成分生物活性应用

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Thermal shock resistance enhancement by improved interfacial bonding for carbon/aluminium composites

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High Voltage 2022年第5期7卷 960-967页

作者： Wenfu Wei Zhanglin Huang Guofeng Yin Zefeng Yang xiaobo Li Haozi zuo Qin Deng Guizao Huang Junwen Ren Qianhua Liao Yan Yang Guangning Wu School of Electrical Engineering Southwest Jiaotong UniversityChengduChina Handley Electronic Co. LtdChangzhouChina College of Electrical Engineering Sichuan UniversityChengduChina School of Electrical&Electronic Engineering Nanyang Technological UniversitySingaporeSingapore

Carbon/aluminium(C/Al)composites have the advantages of low density and high electrical conductivity,which have potential applications in aerospace,rail transportation and other ***,the unstable bonding of the C/Al interface and significant thermal expansion differences have resulted in risks of the composites'failure once suffering from severe thermal *** this work,the C/Al composites were prepared by the pressure impregnation method,and silicon(Si)was added to overcome the problems of C/Al non-wettability and thermal expansion *** effects of mass fractions of doped silicon on the mechanical properties,electrical conductivity and thermal shock resistance of C/Al composites were also *** show that the formed SiC interlayer has effectively enhanced the interfacial bonding and reduced the differences in the thermal expansion coefficient of each *** a result,the thermal shock resistance of the composites has been remarkably improved,and the flexural strength could remain 90%of the original level after the thermal shock test,compared with 50%of that without Si doping.

关键词： composites bonding shock

Indian plate blocked by the thickened Eurasian crust in the middle of the continental collision zone of southern Tibet

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Earthquake Research Advances 2023年第3期3卷 42-52页

作者： Gaochun Wang xiaobo Tian Yibing Li Tao Xu Bo Wan Yi Chen Shitan Nie Xusong Yang Sicheng zuo Jianli Zhang State Key Laboratory of Lithospheric Evolution Institute of Geology and GeophysicsChinese Academy of SciencesBeijing100029China Geothermal and Ecological Geology Research Center School of Ecology and EnvironmentZhengzhou UniversityZhengzhou450001China Innovation Academy for Earth Science CASBeijing100029China Frontiers Science Center for Deep Ocean Multispheres and Earth System Institute for Advanced Ocean StudyOcean University of ChinaQingdao266100China Laboratory for Marine Mineral Resources Pilot National Laboratory for Marine Science and Technology(Qingdao)Qingdao266237China

The relationship of the crustal contact between the Indian and Eurasian plates is a key issue in understanding crustal thickening and the subduction of the Indian lithosphere beneath the Qinghai-Tibetan Plateau. Across the middle of the Yarlung-Zangbo Suture(YZS), we deployed an ~450-km-long SN-trending wide-angle reflection/refraction profile to observe the P-wave velocity(vP) structure beneath the northern Himalaya and the southern plateau. Our results show that, 1. the high vP(~7.1 km/s) indicates that the Indian lower crust extends no more than 50 km north of the YZS. 2. The lower crust beneath the southern part of the plateau features an extremely low vP(<6.7 ± 0.2 km/s). 3. Compared with the velocities of several typical crustal lithologies in different temperature regimes, the low vPin the lower crust can be explained by felsic-intermediate granulite, which has prevented the lower crust from further eclogitization. We propose that the dip angle of the Indian lithospheric slab beneath the YZS is partly controlled by the composition of the lower crust of the plateau. In the northern middle YZS, the crust of the southern plateau is too thick and blocks the northward advancement of the Indian lower crust, resulting in the subduction of the Indian lithospheric slab into the upper mantle. The lower crust in western and eastern Lhasa is dominated by a mafic composition, and it was delaminated after eclogitization before the Miocene. The void zone generated by delamination favors the flattening and underthrusting of the Indian lower crust.

关键词： Qinghai-Tibetan Plateau Indian lithospheric slab Wide-angle reflection/refraction Crustal P-wave velocity structure Crustal thickening

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浙江省优质颗粒形绿茶产业发展现状与思考

中国茶叶加工 2024年第2期 60-64页

作者：苏小琴高玉萍陆德彪黄伟红孔俊豪左小博欧阳诗云宋鹏鹏杨秀芳中华全国供销合作总社杭州茶叶研究所浙江杭州310016 浙江省茶资源跨界应用技术重点实验室浙江杭州310016 浙江农业商贸职业学院浙江绍兴312088 浙江省农业技术推广中心浙江杭州310020 上海师范大学上海201418

颗粒形绿茶是浙江省绿茶的重要品类,团队在调研浙江省优质颗粒形绿茶生产状况、加工工艺和设备、品质现状及标准建设的基础上,研制了浙江省茶叶学会颗粒形绿茶团体标准,对浙江省优质颗粒形绿茶产业的后续发展进行了思考和建议,可为浙江... 详细信息

颗粒形绿茶是浙江省绿茶的重要品类,团队在调研浙江省优质颗粒形绿茶生产状况、加工工艺和设备、品质现状及标准建设的基础上,研制了浙江省茶叶学会颗粒形绿茶团体标准,对浙江省优质颗粒形绿茶产业的后续发展进行了思考和建议,可为浙江省颗粒形绿茶产业健康有序发展提供参考。

关键词：颗粒形绿茶产业现状加工工艺产品特征标准思考和建议

Special issue:Next generation smart transportation systems:envisioning a carbon-neutral,connected,intelligent,equitable transportation

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Frontiers of Engineering Management 2024年第4期11卷 589-591页

作者： xiaobo QU Jonas ELIASSON zuo-Jun(Max)SHEN Fang HE Juan de Dios ORTÚZAR Kai WANG School of Vehicle and Mobility Tsinghua UniversityBeijing 100084China Swedish National Transportation Administration Linkoping UniversitySE-58183 LinköpingSweden HKU Business School University of Hong KongHong KongChina Department of Industrial Engineering Tsinghua UniversityBeijing 100084China Department of Transport Engineering and Logistics Pontificia Universidad Católica de ChileSantiagoChile

In recent years,rapid urbanization,population growth,and increasing concerns about climate change have led to a growing demand for innovative and sustainable transportation *** we strive to meet these challenges,the development of next-generation smart transportation systems has emerged as a critical focus for researchers,industry leaders,and policymakers *** advanced systems have the potential to revolutionize the way we move people and goods,integrating cutting-edge technologies or concepts such as artificial intelligence,electrification,connected and automated driving,and advanced aerial *** special issue aims to provide a platform for the exchange of ideas,research findings,and best practices,fostering a deeper understanding of the opportunities and challenges presented by this paradigm shift in *** exploring the diverse aspects of carbon neutrality,connectivity,intelligence,equity,and verticalization,we hope to foster a multidisciplinary dialogue and shed a light on the development of sustainable,efficient,and equitable transportation solutions for the future.

关键词： neutral smart connected

环境心理学视角下高校图书馆疗愈空间建设策略研究

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图书馆杂志 2024年第4期43卷 90-97页

作者：左丽华池晓波浙江工业大学图书馆浙江杭州310014

为学生健康提供全方位支持已成为高校图书馆服务的新趋势,调研发现空间作为图书馆的优势资源之一在支持学生健康方面并没有得到充分利用。文章引入疗愈空间理念,提出高校图书馆健康空间应支撑学生生理、心理、社会适应性全面健康发展,... 详细信息

为学生健康提供全方位支持已成为高校图书馆服务的新趋势,调研发现空间作为图书馆的优势资源之一在支持学生健康方面并没有得到充分利用。文章引入疗愈空间理念,提出高校图书馆健康空间应支撑学生生理、心理、社会适应性全面健康发展,并从环境心理学理论出发探讨如何系统化建设高校图书馆疗愈空间,最后通过浙江工业大学图书馆空间建设实例论证基于环境心理学理论提出的疗愈空间构建策略。

关键词：环境心理学高校图书馆疗愈空间学生健康