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Brassica rapa Genome 2.0： A Reference Upgrade through Sequence Re-assembly and Gene Re-annotation

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Molecular Plant 2017年第4期10卷 649-651页

作者： Chengcheng cai xiaobo Wang Bo Liu Jian Wu Jianli Liang Yinan Cui Feng Cheng Xiaowu Wang Institute of Vegetables and Flowers Chinese Academy of AgriculturalSciences Key Laboratory of Biology and Genetic Improvement of Horticultural Crops of the Ministry of Agriculture Sino-Dutch Joint Laboratory of Horticultural Genomics Beijing 100081 P.R. China

Brassica rapa includes many important crops that are cultivated as vegetables, condiments, and oilseeds. Recently, the Brassica genomes have been sequenced extensively： a B. rapa draft reference genome in 2011 （Wang et al., 2011）, a Brassica oleracea in 2014 （Liu et al., 2014）, a Brassica napus in 2014 （Chalhoub et al., 2014）, and Brassica nigra and Brassica juncea in 2016 （Yana et al.. 2016）. The first released B.

关键词： Brassica rapa includes important crops vegetables

Teaching Mode of Basic Computer Courses Using Theories and Methods of Computational Thinking

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教育研究前沿（中英文版） 2020年第1期10卷 1-5页

作者： xiaobo cai Ke Han Yan Li College of Big Data Yunnan Agricultural UniversityKunmingChina School of electrical engineering Kunming Metallurgy CollegeKunmingChina

In view of the university computer culture foundation of college course,it is proposed that learners use efficient thinking methods to *** must get rid of the prejudice of traditional teaching"narrow tool theory",based on computing thinking and university computer culture *** paper proposed how to guide learners to use computing thinking to solve related problems in classroom teaching,introduced the application of computing thinking in computer classroom teaching,and proposed a curriculum with"computing thinking"as the *** teaching method provides a new model for the university computer basic education with the goal of improving students'thinking ability.

关键词： Computing Thinking Computer Science University Computer Culture Foundation Teaching Mode

Crystallization and Microstructure of Li_2O-Al_2O_3-SiO_2 Glass-ceramics Produced with Environmentally Acceptable Fining Agents

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Journal of the Chinese Ceramic Society 2015年第2期 91-97页

作者： GUO Xingzhong cai xiaobo SONG Jie YANG Hui School of Materials Science and Engineering Zhejiang University

Lithium aluminosilicate(LAS) glass-ceramics with a few gas bubbles were prepared when SnO2, V2O5 and CeO2 were used as fining agents. The effect of the complex fining agent on the crystallization, phase compositions and microstructure of LAS glass–ceramics was investigated by differential thermal analysis, X-ray diffraction and scanning electron microscopy, respectively. The results show that the introduction of fining agents promotes the crystallization at a lower temperature and has little effect on the compositions of main crystalline phase and microstructure when the crystalline phase remains β-quartz. The special colors of LAS glass-ceramics can be obtained by controlling the crystallization temperature and the amounts of V2O5 and CeO2. The complex fining agent is an environmentally friendly alternative to toxic As2O3 and can be also used as a colorant for colored LAS glass-ceramics.

关键词： lithium aluminosilicate glass-ceramics fining agents crystallization coloration

TRPM2 Mediates Hepatic Ischemia–Reperfusion Injury via Ca^(2+) -Induced Mitochondrial Lipid Peroxidation through Increasing ALOX12 Expression

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Research 2024年第1期2023卷 351-368页

作者： Cheng Zhong Jing Yang Yiyin Zhang Xiaoxiao Fan Yang Fan Ning Hua Duguang Li Shengxi Jin Yirun Li Peng Chen Yongle Chen xiaobo cai Yi Zhang Linhua Jiang Wei Yang Peilin Yu Hui Lin Department of General Surgery Sir Run Run Shaw HospitalSchool of MedicineZhejiang UniversityHangzhouP.R.China Department of Biophysics and Department of Neurology of the Fourth Affiliated Hospital Zhejiang University School of MedicineHangzhou 310000P.R.China Department of Physiology and Pathophysiology and Sino-UK Joint Laboratory of Brain Function and Injury of Henan Province Xinxiang Medical University453003 XinxiangHenanP.R.China School of Biomedical Sciences Faculty of Biological SciencesUniversity of LeedsLS29JT LeedsUK Department of Toxicology and Department of Medical Oncology of Second Affiliated Hospital Zhejiang University School of MedicineHangzhouP.R.China Zhejiang Engineering Research Center of Cognitive Healthcare Sir Run Run Shaw HospitalSchool of MedicineZhejiang UniversityHangzhou 310020P.R.China College of Biomedical Engineering and Instrument Science Zhejiang UniversityHangzhou 310058P.R.China

Hepatic ischemia–reperfusion(IR)injury is a serious clinical problem that complicates liver resection and *** recent advances in understanding of the pathophysiology of hepatic IR injury,effective interventions and therapeutics are still ***,we examined the role of transient receptor potential melastatin 2(TRPM2),a Ca^(2+)-permeable,non-selective cation channel,in mediating hepatic IR *** data showed that TRPM2 deficiency attenuated IR-induced liver dysfunction,inflammation,and cell death in ***,RNA sequencing analysis indicated that TRPM2-induced IR injury occurs via ferroptosis-related ***,as a ferroptosis inducer,(1S,3R)-RSL3 treatment induced mitochondrial dysfunction in hepatocytes and a TRPM2 inhibitor suppressed ***,TRPM2-mediated calcium influx caused mitochondrial calcium accumulation via the mitochondrial Ca^(2+)-selective uniporter and increased the expression level of arachidonate 12-lipoxygenase(ALOX12),which results in mitochondrial lipid peroxidation during hepatic IR ***,hepatic IR injury-induced ferroptosis was obviously relieved by a TRPM2 inhibitor or calcium depletion,both in vitro and in ***,these findings demonstrate a crucial role for TRPM2-mediated ferroptosis in hepatic IR injury via increased Ca^(2+)-induced ALOX12 expression,indicating that pharmacological inhibition of TRPM2 may provide an effective therapeutic strategy for hepatic IR injury-related diseases,such as during liver resection and transplantation.

关键词： TRPM2 Lipid Hepatic

High‑Entropy Electrode Materials:Synthesis,Properties and Outlook

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Nano-Micro Letters 2025年第1期17卷 472-506页

作者： Dongxiao Li Chang Liu Shusheng Tao Jieming cai Biao Zhong Jie Li Wentao Deng Hongshuai Hou Guoqiang Zou xiaobo Ji College of Chemistry and Chemical Engineering Central South UniversityChangsha 410083People’s Republic of China School of Chemistry and Chemical Engineering Hunan Institute of EngineeringXiangtan 411104People’s Republic of China

High-entropy materials represent a new category of high-performance materials,first proposed in 2004 and extensively investigated by researchers over the past two *** definition of high-entropy materials has continuously *** the last ten years,the discovery of an increasing number of high-entropy materials has led to significant advancements in their utilization in energy storage,electrocatalysis,and related domains,accompanied by a rise in techniques for fabricating high-entropy electrode ***,the research emphasis has shifted from solely improving the performance of high-entropy materials toward exploring their reaction mechanisms and adopting cleaner preparation ***,the current definition of high-entropy materials remains relatively vague,and the preparation method of high-entropy materials is based on the preparation method of single metal/low-or medium-entropy *** should be noted that not all methods applicable to single metal/low-or medium-entropy materials can be directly applied to high-entropy *** this review,the definition and development of high-entropy materials are briefly ***,the classification of high-entropy electrode materials is presented,followed by a discussion of their applications in energy storage and catalysis from the perspective of synthesis ***,an evaluation of the advantages and disadvantages of various synthesis methods in the production process of different high-entropy materials is provided,along with a proposal for potential future development directions for high-entropy materials.

关键词： High-entropy Energy storage Electrode materials

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“精明增长”及其对我国城市规划管理的启示

热带地理 2010年第1期30卷 84-89页

作者：蔡小波中山大学地理科学与规划学院广州510275 广州市规划局广州510070

以"精明增长"是否适用于中国的城市规划管理为基本出发点,在理清"精明增长"概念的基础上,分析中国与美国城市发展差异,探讨"精明增长"理念对我国城市规划管理的启示。介绍了"精明增长"产生的背景及内涵,阐述了美国"精明增长"发展计划的... 详细信息

以"精明增长"是否适用于中国的城市规划管理为基本出发点,在理清"精明增长"概念的基础上,分析中国与美国城市发展差异,探讨"精明增长"理念对我国城市规划管理的启示。介绍了"精明增长"产生的背景及内涵,阐述了美国"精明增长"发展计划的实践并对此作出评价。基于中美差异的思考对"精明增长"在我国的应用意义和可行性进行了论述,结合中国国情思考其对我国城市规划管理的启示,提出了从理论实践和技术手法上用"精明增长"的理念来为科学合理的城市规划管理进行理念更新的建议。

关键词：精明增长城市发展规划管理

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车载三天线GNSS的直接法定姿及精度评估

武汉大学学报（信息科学版） 2018年第6期43卷 820-825页

作者：蔡小波许厚泽王勇柴华丁磊香中国科学院测量与地球物理研究所大地测量与地球动力学国家重点实验室湖北武汉430077 中国科学院大学北京100049 河南城建学院河南平顶山467036

针对移动测量系统对载体姿态的需求,对车载三天线全球卫星导航系统（global navigation satellite system,GNSS）的直接法定姿进行了研究。分析了定姿的原理,给出了姿态解算公式,并提出一种简便的方法确定航向角的象限,解决了航向角的... 详细信息

针对移动测量系统对载体姿态的需求,对车载三天线全球卫星导航系统（global navigation satellite system,GNSS）的直接法定姿进行了研究。分析了定姿的原理,给出了姿态解算公式,并提出一种简便的方法确定航向角的象限,解决了航向角的多值性问题。为了评估该方法的精度,利用车载的三天线GNSS进行了动态实验,采集了动态观测数据,利用直接法对观测数据进行了姿态解算,并用同车搭载的一套高精度惯性导航系统（inertial navigation system,INS）给出的姿态参考值对三天线GNSS定姿的精度和可靠性进行了评估。结果表明,三天线GNSS直接法定姿精度高、可靠性好,并具有计算简便,可避免奇异性问题等优点。

关键词：直接法动态定姿基线多值性问题精度可靠性

广州市中心镇建设用地景观格局及其影响因素分析

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热带地理 2011年第5期31卷 478-483页

作者：蔡小波许学强中山大学地理科学与规划学院广州510275

借用景观生态学"景观格局"的概念,运用GIS的空间分析功能,选取中心镇建设用地斑块景观集聚度指数、形状指数和破碎度指数等景观生态学指标,对广州市中心镇的建设用地格局进行定量分析。研究表明,近10年来中心镇的建设用地扩展速度基本... 详细信息

借用景观生态学"景观格局"的概念,运用GIS的空间分析功能,选取中心镇建设用地斑块景观集聚度指数、形状指数和破碎度指数等景观生态学指标,对广州市中心镇的建设用地格局进行定量分析。研究表明,近10年来中心镇的建设用地扩展速度基本呈先下降后上升的趋势,而景观集聚度则基本呈持续下降和先上升而后下降两种态势,景观形状也趋向于复杂化,破碎化程度升高。影响景观格局的要素主要来自于自然条件的制约、城市结构重组、外来投资推动、重大建设项目布局、区域交通牵引等。最后对中心镇的景观优化提出了建议。

关键词：中心镇建设用地景观格局影响因素广州

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失代偿期肝硬化肝功能的再代偿

中华肝脏病杂志 2023年第7期31卷 681-683页

作者：蔡晓波陆伦根上海交通大学医学院附属第一人民医院消化内科上海200080

目前研究认为,经过有效治疗后失代偿期肝硬化出现肝功能的再代偿。然而,肝功能再代偿的程度、肝功能再代偿判断的标准、如何从肝功能的角度预测再代偿等多个问题仍需进一步探索。现从肝功能角度探讨失代偿期肝硬化的再代偿。

关键词：肝硬化失代偿肝功能再代偿