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Analysis of the Application of“Jing(精)”in Ben Cao Gang Mu(《本草纲自〉Compendium of Materia Medica)

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Chinese Medicine and Culture 2020年第2期3卷 99-104页

作者： Yiwen Yang xiaobei jiang Baican Yang School of Pharmacy Shanghai University of Traditional Chinese MedicineShanghaiChina

Taking the Ben Cao Gang Mu(《本草纲目》Compendium of Materia Medica)(Jinling edition金陵本)as the research object and“Jing”as the search term,this article summarizes the quantity of medicinals containing“Jing”in Ben Cao Gang Mu,analyzes the connotation and application of“Jing”in traditional Chinese medicine,and finds that the application of“Jing”in medicine does not deviate from the original meaning of“Jing,”but endows it with the concepts of medicine and pharmacy,and expands the application scope of“Jing.”This study is helpful to understand and use spermicide more reasonably.

关键词： Ben Cao GangMu(《本草纲目》Compendium of Materia Medica) Jing(精) data retrieval Jinling edition literature research traditional Chinese medicine

超高效液相色谱-串联质谱快速测定食品中的新品种甜味剂爱德万甜

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色谱 2018年第7期36卷 700-704页

作者：汪辉黄小贝刘江王柯葛芬长沙市食品药品检验所湖南长沙410016

建立了超高效液相色谱-串联三重四极杆质谱快速筛查和确证食品中的新品种甜味剂爱德万甜的方法。样品经甲醇-水(50∶50,v/v)超声提取,离心,取上清液过滤膜。采用Agilent SB-C18(150 mm×2.1 mm,5μm)色谱柱分离,梯度洗脱,在电喷雾离子... 详细信息

建立了超高效液相色谱-串联三重四极杆质谱快速筛查和确证食品中的新品种甜味剂爱德万甜的方法。样品经甲醇-水(50∶50,v/v)超声提取,离心,取上清液过滤膜。采用Agilent SB-C18(150 mm×2.1 mm,5μm)色谱柱分离,梯度洗脱,在电喷雾离子源的正离子电离模式下,用多反应监测(MRM)方式采集数据,根据保留时间和定性离子对进行定性筛查,根据峰面积和定量离子进行定量分析。结果表明:方法检出限(LOD)为0.03 mg/kg(信噪比S/N≥3),定量限(LOQ)为0.10 mg/kg(S/N≥10),回收率为80.3%~98.0%,在0.01~1.0 mg/L范围内均有良好的线性,相关系数r2均大于0.997。该方法快速、简便易行、灵敏、准确,适用于饮料、酸奶和果冻中的新品种甜味剂爱德万甜的批量检测。

关键词：超高效液相色谱-串联质谱爱德万甜新品种甜味剂食品

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基于摩擦纳米发电机的车辆踏板运动量化模型

机械工程学报 2022年第17期58卷 215-225页

作者：张浩东王武宏陆逍谭海秋蒋晓蓓石健北京理工大学机械与车辆学院北京100081 上海电力大学数学物理学院上海200090

针对当前车辆踏板角度传感器结构复杂,对复杂材料的需要以及对外部电源的依赖等问题,提出一种基于扇形单电极滑动模式摩擦纳米发电机(Sector-single electrode sliding mode triboelectric nanogenerator,S-SETENG)踏板运动量化模型。首... 详细信息

针对当前车辆踏板角度传感器结构复杂,对复杂材料的需要以及对外部电源的依赖等问题,提出一种基于扇形单电极滑动模式摩擦纳米发电机(Sector-single electrode sliding mode triboelectric nanogenerator,S-SETENG)踏板运动量化模型。首先,在单电极滑动模式摩擦纳米发电机(Single electrode sliding mode triboelectric nanogenerator,SETENG)基础上,根据接触面积与开路电压值之间的潜在规律,开发可获取踏板运动信息的S-SETENG。其次,进行模拟驾驶实验,获取自然驾驶状态下的车辆踏板运动数据,包括驾驶模拟器输出的踏板角度数据和S-SETENG输出的电压数据。然后,利用S-SETENG电压数据和车辆踏板角度数据完成踏板运动量化模型的训练。最后,根据模型在测试集上的结果显示,基于门控循环单元网络(Gate recurrent unit,GRU)加速踏板运动量化模型和基于长短记忆网络(Long-short term memory,LSTM)的制动踏板运动量化模型的表现最佳,决定系数(R2)的值都超过0.94,证明该方法的准确性和可行性。这不仅在角度测量领域展示了一种新的方法,而且极大地扩展了摩擦纳米发电机作为自供电传感器的适用性。

关键词：摩擦纳米发电机循环神经网络车辆踏板运动量化模型

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面向视频结构化的细粒度车辆检测分类模型

汽车工程 2021年第10期43卷 1427-1434页

作者：石健成前金立生胡耀光蒋晓蓓郭柏苍王武宏北京理工大学机械与车辆学院北京100081 燕山大学车辆与能源学院秦皇岛066004

针对无人驾驶环境感知技术中存在复杂交通场景理解受限的问题,本文中提出一种面向路侧端的视频结构化框架,通过丰富交通场景中不同目标的细粒度信息,提高复杂交通场景的理解能力。针对所提出的视频结构化框架,提供了一种可工程化的细粒... 详细信息

针对无人驾驶环境感知技术中存在复杂交通场景理解受限的问题,本文中提出一种面向路侧端的视频结构化框架,通过丰富交通场景中不同目标的细粒度信息,提高复杂交通场景的理解能力。针对所提出的视频结构化框架,提供了一种可工程化的细粒度车辆检测分类模型。通过通道剪枝策略对YOLOv4算法进行优化,使压缩模型YOLOv4Pruned在mAP几乎不变的情况下,较原模型体积减小约60%。设计了16种类型、12种颜色的车辆分类方法可有效覆盖当前交通场景下的运行车辆,在测试集上的分类准确率可达93%。本文设计的细粒度车辆检测分类模型在1920×1080输入,NVIDIA GeForce RTX 2080Ti下可稳定在23FPS,在海思Hi3516DV300下,未量化的模型可稳定在13FPS。

关键词：无人驾驶技术路侧端环境感知视频结构化算法细粒度车辆检测分类

Toward understanding the role of genomic repeat elements in neurodegenerative diseases

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Neural Regeneration Research 2025年第3期20卷 646-659页

作者： Zhengyu An Aidi jiang Jingqi Chen Institute of Science and Technology for Brain-Inspired Intelligence Fudan UniversityShanghaiChina MOE Frontiers Center for Brain Science Fudan UniversityShanghaiChina MOE Key Laboratory of Computational Neuroscience and Brain-Inspired Intelligence Fudan UniversityShanghaiChina Zhangjiang Fudan International Innovation Center ShanghaiChina

Neurodegenerative diseases cause great medical and economic burdens for both patients and society;however, the complex molecular mechanisms thereof are not yet well understood. With the development of high-coverage sequencing technology, researchers have started to notice that genomic repeat regions, previously neglected in search of disease culprits, are active contributors to multiple neurodegenerative diseases. In this review, we describe the association between repeat element variants and multiple degenerative diseases through genome-wide association studies and targeted sequencing. We discuss the identification of disease-relevant repeat element variants, further powered by the advancement of long-read sequencing technologies and their related tools, and summarize recent findings in the molecular mechanisms of repeat element variants in brain degeneration, such as those causing transcriptional silencing or RNA-mediated gain of toxic function. Furthermore, we describe how in silico predictions using innovative computational models, such as deep learning language models, could enhance and accelerate our understanding of the functional impact of repeat element variants. Finally, we discuss future directions to advance current findings for a better understanding of neurodegenerative diseases and the clinical applications of genomic repeat elements.

关键词： Alzheimer's disease ataxia deep learning long-read sequencing neurodegeneration neurodegenerative diseases Parkinson's disease repeat element structural variant

Miyaoka-type inequalities for terminal threefolds with nef anti-canonical divisors

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Science China Mathematics 2025年第1期68卷 1-18页

作者： Masataka Iwai Chen jiang Haidong Liu Department of Mathematics Graduate School of ScienceOsaka University Shanghai Center for Mathematical Sciences & School of Mathematical Sciences Fudan University Department of mathematics Sun Yat-sen University

In this paper,we study Miyaoka-type inequalities on Chern classes of terminal projective 3-folds with nef anti-canonical *** X be a terminal projective 3-fold such that-KXis *** show that if c1（X） · c2（X）≠0,then c1（X） · c2（X） ≥ 1/252;if further X is not rationally connected,then c1（X） · c2（X） ≥ 4/5 and this inequality is *** order to prove this,we give a partial classification of such varieties along with many *** also study the nonvanishing of c1（X）dim X-2· c2（X） for terminal weak Fano varieties and prove a Miyaoka-Kawamata-type inequality.

关键词： terminal threefolds Miyaoka-type inequality boundedness

Optimal Scheduling of an Independent Electro-Hydrogen System with Hybrid Energy Storage Using a Multi-Objective Standardization Fusion Method

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Energy Engineering 2025年第1期122卷 63-84页

作者： SuliangMa ZeqingMeng Mingxuan Chen Yuan jiang School of Electrical and Control Engineering North China University of TechnologyBeijing100144China ChinaThree Gorges Technology Co. Ltd.Beijing100032China School of Automation and Electrical Engineering University of Science and Technology BeijingBeijing100083China

In the independent electro-hydrogen system(IEHS)with hybrid energy storage(HESS),achieving optimal scheduling is ***,it presents a challenge due to the significant deviations in values ofmultiple optimization objective functions caused by their physical *** deviations seriously affect the scheduling process.A novel standardization fusion method has been established to address this issue by analyzing the variation process of each objective function’s *** optimal scheduling results of IEHS with HESS indicate that the economy and overall energy loss can be improved 2–3 times under different optimization *** proposed method better balances all optimization objective functions and reduces the impact of their *** the cost of BESS decreases by approximately 30%,its participation deepens by about 1 ***,if the price of the electrolyzer is less than 15￥/kWh or if the cost of the fuel cell drops below 4￥/kWh,their participation will increase *** study aims to provide a more reasonable approach to solving multi-objective optimization problems.

关键词： Electro-hydrogen system multi-objective optimization standardization method hybrid energy storage system

Constraints on holographic QCD phase transitions from PTA observations

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Science China(Physics,Mechanics & Astronomy) 2025年第1期Mechanics & Astronomy) .卷 71-78页

作者： Song He Li Li Sai Wang Shao-jiang Wang Center for Theoretical Physics and College of Physics Jilin University School of Physical Science and Technology Ningbo University Max Planck Institute for Gravitational Physics (Albert Einstein Institute) CAS Key Laboratory of Theoretical Physics Institute of Theoretical Physics Chinese Academy of Sciences School of Fundamental Physics and Mathematical Sciences Hangzhou Institute for Advanced StudyUniversity of Chinese Academy of Sciences (UCAS) School of Physical Sciences University of Chinese Academy of Sciences (UCAS) Theoretical Physics Division Institute of High Energy Physics Chinese Academy of Sciences

The underlying physics of QCD phase transition in the early Universe remains largely unknown due to its strong-coupling nature during the quark-gluon plasma/hadron gas transition, yet a holographic model has been proposed to quantitatively fit the lattice QCD data while with its duration of the first-order phase transition(FoPT) left undetermined. At specific baryon chemical potential, the first-order QCD phase transition agrees with the observational constraint of baryon asymmetry. It, therefore, provides a scenario for phase transition gravitational waves(GWs) within the standard model of particle physics. If these background GWs could contribute dominantly to the recently claimed common-spectrum red noise from pulsar timing array(PTA) observations, the duration of this FoPT can be well constrained, and the associated primordial black holes are still allowed by current observations.

关键词： pulsar timing array QCD phase transition gravitational waves primordial black holes

Effects of carbon content on the microstructure and tensile properties of a low-density steel

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International Journal of Minerals,Metallurgy and Materials 2025年第2期32卷 391-401页

作者： Yongxuan Shang Mingyu Fan Shuyong jiang Zhongwu Zhang Key Laboratory of Superlight Materials and Surface Technology Ministry of EducationCollege of Materials Science and Chemical EngineeringHarbin Engineering UniversityHarbin 150001China State Key Laboratory of Metal Material for Marine Equipment and Application Iron&Steel Research Institute of Ansteel Group CorporationAnshan 114009China

Carbon can change the phase components of low-density steels and influence the mechanical *** this study,a new method to control the carbon content and avoid the formation ofδ-ferrite by decarburization treatment was *** microstructural changes and mechanical characteristics with carbon content induced by decarburization were systematically ***-Jaoul(C-J)analysis was employed to examine the work hardening characteristics during the tensile *** decarburization by heat treatments,the carbon content within the austenite phase decreased,while Mn and Al were almost unchanged;this made the steel with full austenite transform into the austenite and ferrite dual ***,(Ti,V)C carbides existed in both matrix phase and the mole fraction almost the *** addition,the formation of other carbides *** loss induced a decrease in strength due to the weakening of the carbon solid *** the steel with the single austinite,the deformation mode of austenite was the dislocation planar glide,resulting in the formation of *** the dual-phase steel,the deformation occurred by the dislocation planar glide of austenite first,with the increase in strain,the cross slip of ferrite took place,forming dislocation cells in *** the late stage of deformation,the work hardening of austinite increased rapidly,while that of ferrite increased slightly.

关键词： low-density steels carbon content decarburization strengthening mechanisms work hardening behavior