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Science China(Physics,Mechanics & Astronomy) 2015年第10期58卷 18-22页

作者： WANG xiaobao dong GuoXiang School of Science Huzhou University Grand Acc'el'erateur National d’Ions Lourds (GANIL)

This paper is a short revisit to Kuo-Brown effective interaction derived from the Hamada-Johnston nucleon-nucleon potential, done by Gerry Brown and Tom Kuo. This effective interaction, derived in year 1966, is the first attempt to describe nuclear structure properties from the free nucleon-nucleon potential. Nowadays much progress has been achieved for the effective interactions in shell model. We would compare the effective interactions obtained in the 1966 paper with up-to-date shell-model interactions in sd-shell and pf-shell model space. Recent knowledge of effective interactions on nuclear structure, can also be traced in the KuoBrown effective interaction, i.e., the universal roles of central and tensor forces, which reminds us that such discovery should be noticed much earlier.

关键词： shell model effective interactions tensor force

Triaxiality and shape coexistence in the A ～ 30 “island of inversion”nuclei

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Science China(Physics,Mechanics & Astronomy) 2015年第11期58卷 99-106页

作者： dong GuoXiang WANG xiaobao YU ShaoYing School of Science Huzhou University

Understanding the properties of nuclei inside "island of inversion" is still an interesting issue. Based on a simple Nilsson model with a new set of isospin-dependent parameters, and with non-axial deformations considered, we have performed three-dimensional potential-energy-surface calculations for Ne, Na, Mg and Al isotopes that are claimed to be in or nearby the A～30 island of inversion". It is found that shape coexistence and triaxial deformation(or softness) exist in these nuclei. Large deformations are obtained by the improved Nilsson parameters, which explains the observed large electric quadrupole transition probabilities. The large deformations happening in30 Ne,31Na,32 Mg and33Al indicate the quenching of the spherical N = 20 neutron shell gap. The calculations of nuclear binding and two-neutron separation energies have been also improved with the isospin-dependent parameters and the inclusion of the non-axial deformation degree of freedom.

关键词： island of inversion shell evolution triaxial deformation shape coexistence

An investigation of ab initio shell-model interactions derived by no-core shell model

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Science China(Physics,Mechanics & Astronomy) 2016年第9期59卷 52-58页

作者： xiaobao Wang GuoXiang dong QingFeng Li CaiWan Shen ShaoYing Yu School of Science Huzhou University

The microscopic shell-model effective interactions are mainly based on the many-body perturbation theory （MBPT）, the first work of which can be traced to Brown and Kuo＇s first attempt in 1966, derived from the Hamada-Johnstou nucleon-nucleon potential. However, the convergence of the MBPT is still unclear. On the other hand, ab initio theories, such as Green＇s function Monte Carlo （GFMC）, no-core shell model （NCSM）, and coupled-cluster theory with single and double excitations （CCSD）, have made many progress in recent years. However, due to the increasing demanding of computing resources, these ab initio applications are usually limited to nuclei with mass up to A = 16. Recently, people have realized the ab initio construction of valence-space effective interactions, which is obtained through a second-time renormalization, or to be more exactly, projecting the full-many- body Hamiltonian into core, one-body, and two-body cluster parts. In this paper, we present the investigation of such ab initio shell-model interactions, by the recent derived sd-shell effective interactions based on effective J-matrix Inverse Scattering Potential （JISP） and chiral effective-field theory （EFT） through NCSM. In this work, we have seen the similarity between the ab initio shell- model interactions and the interactions obtained by MBPT or by empirical fitting. Without the inclusion of three-body （3-bd） force, the ab initio shell-model interactions still share similar defects with the microscopic interactions by MBPT, i.e., T = 1 channel is more attractive while T = 0 channel is more repulsive than empirical interactions. The progress to include more many-body correlations and 3-bd force is still badly needed, to see whether such efforts of ab initio shell-model interactions can reach similar precision as the interactions fitted to experimental data.

关键词： shell model effective interactions ab initio methods

Collective properties of neon isotopes investigated by projected shell model

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Chinese Science Bulletin 2014年第29期59卷 3847-3852页

作者： Guoxiang dong xiaobao Wang Furong Xu Shaoying Yu State Key Laboratory of Nuclear Physics and Technology School of PhysicsPeking University Department of Physics University of Jyvskyl40014 JyvskylFinland School of Science Huzhou Teachers College

Collective phenomenon in neon isotopes is an interesting ***,even the ground-state deformations cannot be well described by ***,QJ Zhi and ZZ Ren[Phys Lett B 638:166(2006)]have suggested an improved Nilsson potential,which can give a suitable description of ground-state properties in magnesium *** order to test the description of neon isotopes located around the‘‘island of inversion’’,we have used this potential to provide the deformed basis for the projectedshell-model *** low-lying spectra and transition properties of neon isotopes can be reproduced *** gyromagnetic factors of neon isotopes have also been *** structures of excited states along the yrast line are studied in the language of band diagrams.

关键词：氖同位素投影壳模型基态性质集体霓虹灯物理学尼尔森激发态

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医学本科专业遗传学实验中RBL教改研究

中华医学教育探索杂志 2020年第3期19卷 296-299页

作者：谷超苗绪红刘义茹雅维董小宝景亚青李光天津医科大学基础医学院遗传学系 300070

阐述"探究为基础的学习(research-based learning,RBL)"教改在医学本科专业遗传学实验中的具体实施过程,包括转变教师教学理念、整合与拓展实验内容、创新课堂教学形式、编写适用教材、更新考核方式、建立教学效果评价机制等。初步研究... 详细信息

阐述"探究为基础的学习(research-based learning,RBL)"教改在医学本科专业遗传学实验中的具体实施过程,包括转变教师教学理念、整合与拓展实验内容、创新课堂教学形式、编写适用教材、更新考核方式、建立教学效果评价机制等。初步研究显示,RBL教改可激发医学生学习兴趣和潜能,提升其动手实践和科研创新能力。

关键词：探究为基础的学习遗传学本科教学实验教学改革

High-definition colorful perovskite narrowband photodetector array enabled by laser-direct-writing

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Nano Research 2022年第6期15卷 5476-5482页

作者： xiaobao Xu Yuhang dong Yuanzhou Zhang Zeyao Han Jiaxin Liu Dejian Yu Yi Wei Yousheng Zou Bo Huang Jun Chen Haibo Zeng Key Laboratory of Advanced Display Materials and Devices Ministry of Industry and Information TechnologyInstitute of Optoelectronics&NanomaterialsCollege of Material Science and EngineeringNanjing University of Science and TechnologyNanjing 210094China

Narrowband photodetectors as specific spectral sensing pixels have drawn intense attention in multispectral detection due to their distinct characteristic of filter-free spectrum discrimination,in which the emerging halide lead perovskites witness a booming development in their performance and wavelength-selectivity from blue to near-infrared ***,the challenge in integrating perovskite narrowband photodetectors on one chip imposes an impediment on practical *** this work,the combination of laser-direct-writing and ion exchange is proposed as an efficient way to fabricate high-definition colorful sensing array with perovskite narrowband photodetector unit as *** laser irradiation,the photolysis of halocarbon solvent(CHCl_(3),CH_(3)CH_(2)I,etc)releases the halide ions,which brings the ion exchange and gives rise to slow-varying bandgap in single perovskite photoactive *** ion exchange can be controlled via laser irradiation time and focus point,thus enabling precisely engineerable *** optimizing the process,it is successfully applied to develop patterned perovskite narrow blue and green photodetectors array with a high-definition of~53 *** believe this result will make a great step forward to integrate multifunctional perovskite devices on one chip,which will pave the way for perovskite optoelectronic device to the commercial application.

关键词： photodetector narrowband imaging array laser-direct-writing perovskite

Overstory functional groups indicate the legacy of land use in a secondary tropical forest in southwestern China

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Journal of Forestry Research 2024年第5期35卷 91-105页

作者： Yun Deng Wenfu Zhang Min Cao Jinlong dong Hui Chen xiaobao Deng Jiajia Liu Xiaoyang Song Shangwen Xia Liqing Sha Shengdong Yuan Luxiang Lin CAS Key Laboratory of Tropical Forest Ecology Xishuangbanna Tropical Botanical GardenChinese Academy of SciencesMengla 666303People’s Republic of China Center for Plant Ecology Core Botanical GardensChinese Academy of SciencesMengla 666303People’s Republic of China National Forest Ecosystem Research Station at Xishuangbanna Xishuangbanna Tropical Botanical GardenChinese Academy of SciencesMengla 666303People’s Republic of China Department of Life Sciences Fudan UniversityShanghai 570228People’s Republic of China Department of Life Sciences University of Chinese Academy of SciencesBeijing 100049People’s Republic of China

Anthropogenic disturbances are widespread in tropical forests and influence the species composition in the ***,the impacts of historical disturbance on tropical forest overstory recovery are unclear due to a lack of disturbance data,and previous studies have focused on understory *** this study,the purpose was to deter-mine the influence of historical disturbance on the diver-sity,composition and regeneration of overstory species in present *** the 20-ha Xishuangbanna tropical sea-sonal rainforest dynamics plot in southwestern China,the historical disturbance boundaries were delineated based on panchromatic photographs from *** that drove species clustering in the overstory layer(DBH≥40 cm)were analyzed and the abundance,richness and composition of these species were compared among different tree groups based on multiple regression tree *** coefficient of variation of the brightness value in historical panchro-matic photographs from 1965 was the primary driver of spe-cies clustering in the overstory *** abundance and richness of overstory species throughout the regeneration process were similar,but species composition was always *** the proportion of large-seeded and vigorous-sprouting species showed no significant differ-ence between disturbed and undisturbed forests in the tree-let layer(DBH<20 cm),the difference became significant when DBH *** findings highlight that historical disturbances have strong legacy effects on functional group composition in the overstory and the recovery of overstory species was *** group composi-tion can better indicate the dynamics of overstory species replacement during secondary succession.

关键词： Historical disturbance Legacy effects Secondary forests Overstory species Functional groups

成人急性B淋巴细胞白血病患者基因突变谱及预后意义

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中华血液学杂志 2018年第2期39卷 98-104页

作者：冯娟弓晓媛贾玉娇刘凯奇李艳董小宝房秋云汝昆李庆华王慧君赵邢力贾艳楠宋洋田征王敏唐克晶王建祥秘营昌中国医学科学院、北京协和医学院血液病医院血液学研究所实验血液学国家重点实验室天津300020

【摘要】目的探讨成人急性B淋巴细胞白血病（B—ALL）患者的基因突变谱，并分析其对患者预后的影响。方法收集113例2009年6月至2015年9月收治的成人B—ALL患者DNA标本，采用靶向特异的二代测序技术，针对血液恶性疾病相关的112种基因进... 详细信息

【摘要】目的探讨成人急性B淋巴细胞白血病（B—ALL）患者的基因突变谱，并分析其对患者预后的影响。方法收集113例2009年6月至2015年9月收治的成人B—ALL患者DNA标本，采用靶向特异的二代测序技术，针对血液恶性疾病相关的112种基因进行突变分析，通过多个数据库筛选出可能致病的基因突变，描述其发生频谱，并通过Kaplan—Meier、Cox回归模型分析突变基因对患者总生存（OS）和无复发生存（RFS）的影响。结果113例患者中103例（92．0％）发生至少一种基因突变，29例（25．6％）患者发生≥3种基因突变。所有患者中突变率较高的基因有SFl、FATl、MPL、PTPNll、NRAS等，Ph阳性B—ALL和Ph阴性B—ALL患者中基因突变特点不尽一致。进一步分析基因突变对患者预后的影响，发现在Ph阴性B—ALL中伴JAK—STAT信号通路相关基因突变的患者（如JAKl、JAK2突变）较该信号通路未受影响的患者预后差（OS：P值分别为0．011和0．001；RFS：P值分别为0．014和〈0．001），而伴PTPNll突变的B—ALL患者较不伴PTPN11突变的患者有较好的OS及RFS，但差异无统计学意义（P值均〉0．05）；在Ph阳性***患者中，表观遗传学修饰相关的信号通路异常的患者预后较差（OS：P=0．038；RFS：P=0．047）。结论基因突变在成人***中存在普遍性，发生频谱因亚型而异，涉及多种信号通路，JAK家族相关基因突变常提示患者预后较差，突变基因之间的共存现象也预示着成人B—ALL患者的遗传复杂性和不稳定性。

关键词：白血病,B细胞二代测序技术 DNA突变分析预后

Curcumin ameliorates hippocampal neuron damage induced by human immunodeficiency virus-1

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Neural Regeneration Research 2013年第15期8卷 1368-1375页

作者： Hongmei Tang Rui Pan Wenli Fang Yanyan Xing Dexi Chen xiaobao Chen Yuanyuan Yu Junbing Wang Zheng Gong Guoyin Xiong Jun dong Department of Pathophysiology Key Laboratory of State Administration of Traditional Chinese Medicine Medical College of Jinan University Institute of Brain Research Medical College of Jinan University Joint Laboratory for Brain Function and Health of Jinan University and the University of Hong Kong Department of Orthopedics First Affiliated Hospital Medical College of Jinan University STD/AIDS Research Lab Beijing Youan Hospital Capital Medical University

Our previous studies have shown that infection with the gp120 V3 loop can cause human immunodeficiency virus-1 associated neurocognitive disorders. Curcumin has been shown to improve these effects to some degree, but the precise mechanisms remain unknown. The present study analyzed the neuroprotective effect and mechanism of curcumin in relation to hippocampal neurons. Results showed that 1 nmol/L gp120 V3 loop suppressed the growth of synapses. After administration of 1 !umol/L curcumin, synaptic growth improved. Curcumin is neuroprotective against gp120 V3 loop-induced neuronal damage by inhibiting the activation of L-type calcium currents, relieving intracellular Ca^2＋ overload, promoting Bcl-2 expression, and inhibiting Bax activation. The effect of curcumin was identical to nimodipine, suggesting that curcumin has the same neuroprotective effects against gp120 V3 loop-induced neuronal damage.

关键词： neural regeneration traditional Chinese medicine curcumin gp120 V3 loop humanimmunodeficiency virus-1 associated neurocognitive disorders Ca^2+ synapse apoptosis grants-supported paper neuroregeneration