检索结果-南通市图书馆

Science China Materials 2021年第9期64卷 2202-2211页

作者： Yaqian Wang Yongli Shen Xiong xiao Linxiu Dai Shuang yao Changhua An Life and Health Institute Tianjin Key Laboratory of Organic Solar Cells and Photochemical ConversionSchool of Chemistry and Chemical EngineeringTianjin University of TechnologyTianjin 300384China Tianjin Key Laboratory of Advanced Functional Porous Materials Institute for New Energy Materials&Low-Carbon TechnologiesSchool of Materials Science and EngineeringTianjin University of TechnologyTianjin 300384China

Metastable 1T’MoTe_(2) has attracted much attention as a cost-effective electrocatalyst for hydrogen evolution reaction(HER)in recent ***,few studies were done over common stable 2 H phase because it often exhibits inferior ***,stable 2H MoTe_(2) with S-doped Te vacancies has been synthesized by one-step telluride conversion of 1T MoS_(2) at 700℃under Ar/H_(2) *** is demonstrated that the synergistic effect of S-doping and Te vacancies changes the electronic structures of the *** functional theory(DFT)studies show that plentiful electrons accumulate on the surface S atoms in S-doped Te vacancies of 2H MoTe_(2) catalyst,which may be as active sites to promote ***,the as-synthesized catalyst can be directly used as working electrode,and realizes current density of 100 mA cm^(-2) at overpotential of 217 mV with Tafel slope of 94 mV dec^(-1).This work stimulates intensive studies on the activation of inert phase of other nanocatalysts towards various reactions.

关键词： MoTe_(2) defect electrocatalysis hydrogen evolution

Thymol Protects against Aspergillus Fumigatus Keratitis by Inhibiting the LOX-1/IL-1βSignaling Pathway

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Current Medical Science 2022年第3期42卷 620-628页

作者： Li-mei WANG Hua YANG Hai-jing YAN Rui-feng GE Yun-xiao WANG Sha-sha XUE Lin LI Le-yu LYU cheng-ye CHE Department of Ophthalmology the Affiliated Hospital of Qingdao UniversityQingdao 266003China Department of Otorhinolaryngology-Head and Neck Surgery the Affiliated Hospital of Qingdao UniversityQingdao 266003China

Objective To explore the anti-inflammatory effects and mechanisms of action of thymol in Aspergillus fumigatus(***)*** The minimum inhibitory concentration of thymol against *** was *** characterize the anti-inflammatory effects of thymol,mouse corneas and human corneal epithelial cells were pretreated with thymol or dimethyl sulfoxide(DMSO)before infection with *** ***-lamp microscopy,immunohistochemistry,myeloperoxidase detection,quantitative real-time polymerase chain reaction,and Western blotting were used to assess *** and macrophage recruitment,in addition to the secretion of LOX-1 and IL-1β,were quantified to evaluate the relative contribution of thymol to the inflammatory *** We confirmed that the growth of *** was directly inhibited by *** contrast with the DMSO group,there was a lower degree of inflammation in the mouse corneas of the thymol-pretreated *** was characterized by significantly lower clinical scores,less inflammatory cell infiltration,and lower expression of LOX-1 and IL-1β.Similarly,in vitro experiments indicated that the production of LOX-1 and IL-1βwas significantly inhibited after thymol treatment,in contrast with the DMSO-pretreated *** Our findings demonstrate that thymol exerted a direct fungistatic activity on ***,thymol played a protective role in fungal keratitis by inhibiting LOX-1/IL-1βsignaling pathway and reducing the recruitment of neutrophils and macrophages.

关键词： keratitis Aspergillus fumigatus thymol LOX-1 IL-1β

Limit analysis of ultimate uplift capacity and failure mechanism ofshallow plate anchors in multi-layered soils

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Central South University 2022年第6期29卷 2049-2061页

作者： LYU cheng WANG Zhu-hong ZENG Zheng-qiang ZHANG xiao State Key Laboratory of Hydraulics and Mountain River Engineering Sichuan UniversityChengdu 610065China College of Water Resource and Hydropower Sichuan UniversityChengdu 610065China School of Civil Engineering Southwest Jiaotong UniversityChengdu 610000China College of Civil Engineering Tongji UniversityShanghai 200092China

Considering the fact that in some complex cases,plate anchors are buried in multi-layered geotechnical materials,the ultimate dynamic analysis was performed to investigate the uplift capacity and failure mechanism of shallow strips and circular plate anchors in multi-layered *** nonlinear strength criterion and non-associated flow rule of geotechnical materials were introduced to investigate the influence of nonuniformity on the pullout performance and failure mechanism of shallow plate *** expressions of the detaching curves or surfaces were obtained to reflect the failure mechanism,which can be used to figure out the ultimate uplift capacity and failure *** results are generally in agreement with the numerical simulations and previous *** effects of various parameters on the ultimate uplift capacity and failure mechanism of plate anchors in multi-layered soils were investigated,and it is found that the ultimate uplift capacity and failure range of shallow anchors increase with the increase of initial cohesion and dilatancy coefficient,but decrease with the unit weight,axial tensile stress and nonlinear coefficient.

关键词： limit analysis dilatancy coefficient ultimate uplift capacity plate anchors multi-layered soils

Gastric Cancer Screening by Combined Determination of Serum Helicobacter pylori Antibody and Pepsinogen Concentrations： ABC Method for Gastric Cancer Screening

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Chinese Medical Journal 2018年第10期131卷 1232-1239页

作者： Xian-Zhe Chen cheng-Zhi Huang Wei-Xian Hu Ying Liu Xue-Qing yao Second Clinical Medical College Southern Medical University Guangzhou Guangdong 510515 China Department of General Surgery Guangdong General Hospital Guangdong Academy of Medical Sciences Guangzhou Guangdong 510080 China Medical College Shantou University Shantou Guangdong 515063 China Reproductive Department Guangdong General Hospital Guangdong Academy of Medical Sciences Guangzhou Guangdong 510080 China

Objective：Gastroscopy combined with gastric mucosa biopsies is currently regarded as a gold standard for diagnosis of gastric ***,its application is restricted in clinical practice due to its invasive property.A new noninvasive population screening process combining the assay ofanti-Helicobacterpylori antibody and serum pepsinogen （PG）（ABC method） is adopted to recognize the high-risk patients for further endoscopy examination,avoiding the unnecessary gastroscopy for most population and saving the cost consumption for mass screening ***,controversies exist for the grouping of ABC method and the intervals of gastroscopy surveillance for each *** this review,we summarized these popular concerned topics for providing useful references to the healthcare practitioner in clinical *** Sources：The PubMed databases were systematically searched from the inception dates to November 22,2017,using the keywords ＂Helicobacterpylori,＂＂Pepsinogens,＂ and ＂Stomach Neoplasms.＂Study Selection：Original articles and reviews on the topics were ***：*** antibody and serum PG concentration showed significant changes under the different status *** infection and the progression of atrophic gastritis,which can be used for risk stratification of gastric cancer in *** addition,anti-H,pylori antibody titer can be used for further risk stratification of gastric cancer contributing to determine better endoscopy surveillance ***：The early detection and diagnosis of gastric cancer benefit from the risk stratification,but the cutoff values for *** antibody and serum PG concentration require further modification.

关键词： Gastroscopy Surveillance Helicobacterpylori Antibody Pepsinogens Risk Stratification Stomach Neoplasms

Thyroid Hormone Biomonitoring:A Review on Their Metabolism and Machine-Learning Based Analysis on Effects of Endocrine Disrupting Chemicals

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Environment & Health 2024年第6期2卷 350-372页

作者： Shijie Chen Mengjie Yu Yiming yao Yongcheng Li Ana He Zijun Zhou Liyang Pan Nan xiao Haining Luo Hongwen Sun MOE Key Laboratory of Pollution Processes and Environmental Criteria College of Environmental Science and EngineeringNankai UniversityTianjin 300071China Tianjin Tianshi College Tianjin 301700China Dalian Center for Disease Control and Prevention DalianLiaoning Province 116000China Department of Center for Reproductive Medicine Tianjin Central Hospital Of Gynecology Obstetrics/Tianjin Key Laboratory Of Human Development And Reproductive RegulationTianjin 300052China

The thyroid is an essential endocrine organ in human body,and thyroid hormones(THs)are pivotal signaling molecules and mediators in various physiological ***,particularly in their free form,play a critical role in regulating body temperature and in the metabolism of lipid and glucose,making the maintenance of TH levels crucial for human *** undergo a series of metabolic processes,producing TH metabolites(THMs).THMs are significant in endocrine regulation,such as 3,5-diiothyronine(3,5-T2)and 3-iodothyronamine(3-T1AM),which exhibit activities akin to *** production and distribution of THMs are intricately linked to the function of specific organs and tissues,highlighting the need for advanced research into the determination and mechanisms of THMs in *** to endocrine disrupting chemicals(EDCs)can significantly affect the levels of thyroid stimulating hormone(TSH)and *** review utilizes machine learning to analyze epidemiological data,identifying potential EDCs that pose risks of hyperthyroidism and ***,it delves into the toxicological mechanisms of these EDCs,examining their effects on TH production,binding processes,related proteins,and metabolic *** approach effectively bridges the gap between epidemiological studies and toxicological researches,laying the groundwork for future research *** integrating epidemiological studies with machine learning,this review offers insightful perspectives on the potential risks associated with chemical exposure and underscores the necessity for further research in understanding the impact of EDCs on TH metabolism and TH-related health effects.

关键词： Thyroid stimulating hormone Emerging contaminants Data mining Thyroxine 3,3′,5-Triiodothyronine Homeostasis

The MdABI5 transcription factor interacts with the MdNRT1.5/MdNPF7.3 promoter to fine-tune nitrate transport from roots to shoots in apple

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Horticulture Research 2021年第1期8卷 3131-3143页

作者： Ya-Jing Liu Ning Gao Qi-Jun Ma Jiu-cheng Zhang Xun Wang Jing Lu Yu-Jin Hao xiao-Fei Wang Chun-Xiang You State Key Laboratory of Crop Biology Shandong Collaborative Innovation Center of Fruit&Vegetable Quality and Efficient ProductionCollege of Horticulture Science and EngineeringShandong Agricultural UniversityTai-AnShandong 271018China

Nitrate is a major nitrogen resource for plant growth and development and acts as both a crucial nutrient and a signaling molecule for plants;hence,understanding nitrate signaling is important for crop *** acid(ABA)has been demonstrated to be involved in nitrate signaling,but the underlying mechanism is largely unknown in *** this study,we found that exogenous ABA inhibited the transport of nitrate from roots to shoots in apple,and the transcription of the nitrate transporter MdNRT1.5/MdNPF7.3 was noticeably reduced at the transcriptional level by ABA,which inhibited the transport of nitrate from roots to ***,it was found that the ABA-responsive transcription factor MdABI5 bound directly to the ABRE recognition site of the MdNRT1.5 promoter and suppressed its *** of MdABI5 inhibited ABA-mediated transport of nitrate from roots to ***,these results demonstrate that MdABI5 regulates the transport of nitrate from roots to shoots partially by mediating the expression of MdNRT1.5,illuminating the molecular mechanism by which ABA regulates nitrate transport in apple.

关键词： ABI5 nitrate roots

铥原子4f^(13)(^(2)F_(5/2)^(0))6s6p(^(1)P_(1)^(0))(5/2,1)_(7/2)和4f^(13)(^(2)F_(5/2)^(0))6s6p(^(1)P_(1)^(0))(5/2,1)_(5/2)激发态近阈限光电离截面测量

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

原子与分子物理学报 2025年第4期42卷 100-107页

作者：张振美袁紫灵王郅诚华泽丰姚关心杨新艳孙中发秦正波郑贤锋安徽师范大学物理与电子信息学院芜湖241000

本文利用了激光烧蚀技术、激光泵浦-探测技术、共振增强多光子电离技术(REMPI)和飞行时间质谱技术(TOF-MS)相结合的实验方法研究了镧系金属铥原子激发态近阈限光电离截面.实验研究了Tm原子在291.00~293.50 nm波长范围内的REMPI光谱,在... 详细信息

本文利用了激光烧蚀技术、激光泵浦-探测技术、共振增强多光子电离技术(REMPI)和飞行时间质谱技术(TOF-MS)相结合的实验方法研究了镧系金属铥原子激发态近阈限光电离截面.实验研究了Tm原子在291.00~293.50 nm波长范围内的REMPI光谱,在电离富余能0.2~1.0 eV内,测量了Tm原子4f^(13)(^(2)F_(5/2)^(0))6s6p(^(1)P_(1)^(0))(5/2,1)_(7/2)和4f^(13)(^(2)F_(5/2)^(0))6s6p(^(1)P_(1)^(0))(5/2,1)_(5/2)激发态的光电离截面,测量值在(3.3±0.2)Mb~(13.9±1.3)Mb范围内.

关键词：铥原子光电离截面泵浦-探测镧系金属

Breathing Metal-Organic Polyhedra Controlled by Light for Carbon Dioxide Capture and Liberation

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

CCS Chemistry 2021年第6期3卷 1659-1668页

作者： yao Jiang Peng Tan Shi-Chao Qi Chen Gu Song-Song Peng Fan Wu xiao-Qin Liu Lin-Bing Sun State Key Laboratory of Materials-Oriented Chemical Engineering College of Chemical EngineeringNanjing Tech UniversityNanjing 211816

Metal-organic polyhedra(MOPs)have emerged as versatile platforms for artificial models of biological systems due to their discrete structure and modular ***,the design and fabrication of MOPs with special functionality for mimicking biological processes are *** by the breathing mechanism of lungs,we developed a new type of MOP(a breathing MOP,denoted as NUT-101)by directly using azobenzene units as the pillars of the polyhedra to coordinate with Zr-based metal *** addition to considerable thermal and chemical stability,the obtained MOP exhibits photocontrollable breathing *** irradiation with visible or UV light,the configuration of azobenzene units transforms,leading to reversible expansion or contraction of the cages and,correspondingly,capture or liberation of CO_(2)*** a breathing behavior of NUT-101 is further confirmed by density functional theory(DFT)*** system might establish an avenue for the construction of new materials with particular functionality that mimic biological processes.

关键词： metal-organic polyhedra breathing photoresponsive systems adsorbents carbon dioxide capture

Anomalous extensive landfast sea ice in the vicinity of Inexpressible Island, Antarctica

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Advances in Polar Science 2019年第4期30卷 406-411页

作者： ZHAI Mengxi ZHAO Tiancheng HUI Fengming cheng xiao LIUAobo YUAN Jiawei YU Yining DING Yifan MNR Key Laboratory for Polar Science Polar Research Institute of ChinaShanghai 200136China School of Environmental Science Nanjing Xiaozhuang UniversityNanjing 211171China School of Geospatial Engineering and Science Sun Yat-Sen UniversityGuangzhou 510275China College of Global Change and Earth System Science Beijing Normal UniversityBeijing 100875China

On 10 December 2017,a Chinese research vessel R/V Xuelong encountered an extensive area of landfast ice offshore Inexpressible Island(Antarctica)near the location where the fifth Chinese Antarctic research station is to be *** multi-source satellite images and weather data,we analyzed the ice conditions during the event season and reconstructed the development of landfast *** stages in late September and early October were identified as contributing to the final ice *** two events are highly related to local-and large-scale weather *** images from 2003 to 2017 showed that four in fifteen years experienced severe landfast ice conditions,suggesting that it is not a rare phenomenon.

关键词： Inexpressible Island Antarctic landfast ice Chinese Antarctic research station

Delivery of pOXR1 through an injectable liposomal nanoparticle enhances spinal cord injury regeneration by alleviating oxidative stress

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Bioactive Materials 2021年第10期6卷 3177-3191页

作者： Jing Zhang yao Li Jun Xiong Helin Xu Guanghen Xiang Mingqiao Fan Kailiang Zhou Yutian Lin Xiangxiang Chen Lin Xie Hongyu Zhang Jian Wang Jian xiao Department of Hand Surgery and Peripheral Neurosurgery The First Affiliated Hospital and School of Pharmaceutical SciencesWenzhou Medical UniversityWenzhou325025China Department of Orthopaedics The Second Affiliated Hospital and Yuying Children’s Hospital of Wenzhou Medical UniversityWenzhou325000China

Oxidation resistance 1(OXR1)is regarded as a critical regulator of cellular homeostasis in response to oxidative ***,the role of OXR1 in the neuronal response to spinal cord injury(SCI)remains *** the other hand,gene therapy for SCI has shown limited success to date due in part to the poor utility of conventional gene *** this study,we evaluated the function of OXR1 in SCI and developed an available carrier for delivering the OXR1 plasmid(pOXR1).We found that OXR1 expression is remarkably increased after SCI and that this regulation is protective after ***,we assembled cationic nanoparticles with vitamin E succinate-graftedε-polylysine(VES-g-PLL)(Nps).The pOXR1 was precompressed with Nps and then encapsulated into cationic *** particle size of pOXR1 was compressed to 58 nm,which suggests that pOXR1 can be encapsulated inside liposomes with high encapsulation efficiency and stability to enhance the transfection *** agarose gel results indicated that Nps-pOXR1-Lip eliminated the degradation of DNA by DNase I and maintained its activity,and the cytotoxicity results indicated that pOXR1 was successfully transported into cells and exhibited lower ***,Nps-pOXR1-Lip promoted functional recovery by alleviating neuronal apoptosis,attenuating oxidative stress and inhibiting ***,our study provides considerable evidence that OXR1 is a beneficial factor in resistance to SCI and that Nps-Lip-pOXR1 exerts therapeutic effects in acute traumatic SCI.

关键词： Gene therapy OXR1 DNA condensed agent Spinal cord injury Oxidative stress