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Clinicopathological differences between patients with schistosomal appendicitis and non schistosomal appendicitis:A retrospectively study of past ten years

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World Journal of Clinical Cases 2025年第2期13卷 24-32页

作者： xiao-Yi wang Yao Hao Zi-Jian wang Xiu-Liang Xu Jiang-Hua yang Department of Infectious Diseases The First Affiliated of Wannan Medical CollegeWuhu 241001Anhui ProvinceChina

BACKGROUND Chronic schistosomiasis causes multiple organ and multiple system diseases,especially the digestive *** eggs are mainly deposited in the stomach,liver and colorectal,but a few eggs are deposited in the appendix and cause *** present,there are few studies on schistosomal *** To explore the differences in epidemiological,clinical and pathological characteristics between schistosomal appendicitis and non-schistosomal appendicitis over the past decade in order to assess the impact of schistosomiasis on *** The differences of general data,clinical data and laboratory examination data of patients with appendicitis from October 2013 to October 2023 were retrospectively *** patients were divided into two groups for *** were 136 patients in schistosomal appendicitis group and 5418 patients in non-schistosomal appendicitis *** Schistosomal appendicitis accounted for 2.45%of all patients with appendicitis,and the annual proportion in the past decade was 2.2%,2.9%,1.8%,1.9%,3.4%,3.1%,1.9%,1.6%,3%,2.6%,*** prevalence of schistosomal appendicitis was middle-aged and elderly males,with an average age of 61.73±15.335 *** main population of non-schistosomal appendicitis was middle-aged men,with an average age of 35.8±24.013 years(P<0.001).The distribution of pathological types of appendicitis was different between the two groups(P<0.001).The incidence of acute suppurative appendicitis in non-schistosomal appendicitis was higher than that in schistosomal appendicitis[odds ratio(OR)=0.504;95%confidence interval(CI):0.349-0.728;P<0.001].The proportion of acute attack of chronic appendicitis in schistosomal appendicitis was higher than that in non-schistosomal appendicitis(OR=2.614;95%CI:1.815-3.763;P<0.001).The proportion of schistosomal appendicitis patients complicated with colorectal cancer was higher than that of nonschistosomal appendicitis patients(OR=5.087;95%CI:1.427-

关键词： Schistosomal appendicitis Schistosomiasis Appendix Colorectal cancer Clinicopathological characteristics

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Genes and proteins expressed at different life cycle stages in the model protist Euplotes vannus revealed by both transcriptomic and proteomic approaches

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Science China Life Sciences 2025年第1期68卷 232-248页

作者： Yaohan Jiang xiao Chen Chundi wang Liping Lyu Saleh A.Al-Farraj Naomi A.Stover Feng Gao Key Laboratory of Evolution & Marine Biodiversity (Ministry of Education) and Institute of Evolution & Marine Biodiversity Ocean University of China Marine College Shandong University Zoology Department College of ScienceKing Saud University Department of Biology Bradley University Laboratory for Marine Biology and Biotechnology Qingdao Marine Science and Technology Center

Sexual reproduction first appeared in unicellular protists and has continued to be an essential biological process in almost all *** protists, which contain both germline and somatic genomes within a single cell, have evolved a special form of sexual reproduction called conjugation that involves mitosis, meiosis, fertilization, nuclear differentiation, genome rearrangement, and the development of unique cellular structures. The molecular basis and mechanisms of conjugation vary dramatically among ciliates, and many details of the process and its regulation are still largely unknown. In order to better comprehend these processes and mechanisms from an evolutionary perspective, this study provides the first comprehensive overview of the transcriptome and proteome profiles during the entire life cycle of the newly-established marine model ciliate Euplotes vannus. Transcriptome analyses from 14 life cycle stages(three vegetative stages and 11 sexual stages) revealed over 26,000 genes that are specifically expressed at different stages, many of which are related to DNA replication,transcription, translation, mitosis, meiosis, nuclear differentiation, and/or genome rearrangement. Quantitative proteomic analyses identified 338 proteins with homologs associated with conjugation and/or somatic nuclear development in other ciliates, including dicer-like proteins, Hsp90 proteins, RNA polymerase Ⅱ and transcription elongation factors, ribosomal-associated proteins, and ubiquitin-related proteins. Four of these homologs belong to the PIWI family, each with different expression patterns identified and confirmed by RT-qPCR,which may function in small RNA-mediated genome rearrangement. Proteins involved in the nonhomologous end-joining pathway are induced early during meiosis and accumulate in the developing new somatic nucleus, where more than 80% of the germline sequences are eliminated from the somatic genome. A number of new candidate genes and proteins likely t

关键词： sexual reproduction transcriptomic proteomic genome rearrangement PIWI NHEJ

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新型酯类环氧液晶的合成及应用

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高分子材料科学与工程 2008年第2期24卷 39-42页

作者：杨小王陆绍荣虞锦洪吴兵桂林工学院有色金属材料及其加工新技术省部共建教育部重点实验室广西桂林541004

采用相转移催化剂合成液晶环氧预聚物(PHQEP),用红外光谱、核磁共振谱、广角X射线衍射及偏光显微镜(POM)对PHQEP的分子结构和液晶性进行表征。研究了PHQEP增韧改性环氧树脂固化体系的力学性能,通过DSC、TGA及SEM等测试手段对材料的结构... 详细信息

采用相转移催化剂合成液晶环氧预聚物(PHQEP),用红外光谱、核磁共振谱、广角X射线衍射及偏光显微镜(POM)对PHQEP的分子结构和液晶性进行表征。研究了PHQEP增韧改性环氧树脂固化体系的力学性能,通过DSC、TGA及SEM等测试手段对材料的结构与性能进行了表征。结果表明,PHQEP是典型的向列型液晶,加入PHQEP的环氧固化体系,韧性和热稳定性都有很大的提高。

关键词：环氧树脂液晶环氧韧性热稳定性

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Innovative dual-mode device integrating capacitive desalination and solar vapor generation for high-efficiency seawater desalination

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Journal of Energy Chemistry 2025年第1期100卷 171-179页

作者： Jiacheng wang Zhaoyu Chen Ruduan Yuan Jiaxin Luo Ben Zhang Keju Ji Meng Li Juanxiu xiao Kuan Sun National Innovation Center for Industry-Education Integration of Energy Storage Technology MOE Key Laboratory of Low-grade Energy Utilization Technologies and SystemsCollege of Energy & Power Engineering Chongqing University Xuefeng Mountain Energy Equipment Safety National Observation and Research Station CQU-NUS Renewable Energy Materials & Devices Joint Laboratory Chongqing University Southwest Technology and Engineering Research Institute Jiangsu Provincial Key Laboratory of Bionic Functional Materials College of Mechanical and Electrical Engineering Nanjing University of Aeronautics and Astronautics State Key Laboratory of Marine Resources Utilization in South China Sea Collaborative Innovation Center of Marine Science and Technology School of Marine Science and Engineering Hainan University

Solar-driven interface evaporation with high solar-to-steam conversion efficiency has shown great potential in seawater ***,due to the influence of latent heat and condensation efficiency,the water yield from solar-driven interface evaporation remains insufficient,posing a significant challenge that requires *** this work,we designed a dual-mode high-flux seawater desalination device that combines solar-driven interface evaporation and capacitive *** utilizing coupled desalination materials exhibiting both photothermal conversion and capacitance activity,the device demonstrated photothermal evaporation rates of 1.41 and 0.97 kg m-2h-1for condensate water yield under one-sun ***,the device exhibited a salt adsorption capacity of up to48 mg g-1and a salt adsorption rate of 2.1 mg *** addition,the salt adsorption capacity increased by approximately 32% under one-sun ***,photo-enhanced capacitive desalination performance was explored through numerical simulations and theoretical *** calculations and characterizations confirmed that the defect energy levels formed by the introduction of sulfur vacancies can effectively widen the light absorption range,improve photothermal conversion performance,and stimulate more photoelectrons to participate in capacitive ***,the electron distribution state of molybdenum disulfide with sulfur vacancies and surface defect sites contributes to ion/electron transport at the solid-liquid *** work provides a novel pathway for integrating solar vapor generation with other low-energy desalination technologies.

关键词： Desalination

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大牛地气田泥砂岩间互层穿层压裂影响因素分析

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石油化工高等学校学报 2017年第3期30卷 32-38页

作者：万军凤肖阳王明中国石油大学胜利学院油气工程学院山东东营257061 成都理工大学能源学院四川成都610059 中国石油塔里木油田分公司天然气事业部新疆库尔勒841000

大牛地气田砂泥岩互层较多,水平井开采虽然可以实现单层储量的最大动用,但是无法同时开采纵向上多个储层,针对这类储层展开可控穿层压裂技术研究,有效合理地开发间互层,实现盒1和山2储层共同动用。结合单井数据,对工区内隔层厚度和水平... 详细信息

大牛地气田砂泥岩互层较多,水平井开采虽然可以实现单层储量的最大动用,但是无法同时开采纵向上多个储层,针对这类储层展开可控穿层压裂技术研究,有效合理地开发间互层,实现盒1和山2储层共同动用。结合单井数据,对工区内隔层厚度和水平主应力差进行对比计算,以分析储、隔层性质、人为可控因素对穿层压裂的影响。综合考虑多种因素,以储层厚度和应力差为依据,初步形成了穿层界限判别标准,并通过井温测井验证单井隔层压开与否,最后形成了一套构建在储层性质精细描述之上,结合多种施工工艺的可控参数优选方法,可为其它井设计和优化提供参考。

关键词：大牛地气田泥砂岩间互层穿层压裂影响因素井温监测

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Thalamic neurons in birds are monocular but encode luminance in both eyes

Thalamic neurons in birds are monocular but encode luminance...

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中国神经科学学会第九届全国学术会议暨第五次会员代表大会

作者： Yan yang,Qian xiao,Qian wang,yang yang,Rui-Feng LIU,Shu-Rong wang~* State Key Laboratory of Brain and Cognitive Science,Institute of Biophysics,Chinese Academy of Sciences,15 Datun Road,Beijing 100101,China

＜正＞Thalamic neurons in birds receive photic input from the contralateral eye only and thus are monocular for object ***,we found by single-cell recording from the lateral-eyed pigeon that a population of visual cells in the nucleus opticus principalis thalami,homologue of the mammalian lateral geniculate nucleus,can encode retinal luminance in both *** thalamic cells are classified into four types characterized respectively by bilateral enhancement,bilateral suppression,contralateral enhancement /ipsilateral suppression or contralateral suppression/ ipsilateral enhancement of firing rates when light is applied alternately to either *** ipsilateral responses recorded after the ipsilateral eye is enucleated are similar to those when the eye is *** latency of ipsilateral responses is identical to that of contralateral ones regardless the ipsilateral eye is intact or *** sum of contralateral and ipsilateral responses evoked in a single neuron by individual eye stimulation is equivalent in strength to the total responses by simultaneous stimulation of both eyes.A mixture of synaptic blockers injected intravitreally into the contralateral eye could reversibly eliminate ipsilateral responses and reduce contralateral *** these indicate that ipsilateral responses of luminance encoding thalamic cells are elicited by ipsilateral light which shines into the contralateral eye through thin and transparent interocular tissues,and contralateral and ipsilateral responses may originate mainly from intrinsically photoreceptive retinal ganglion cells in the inner retina and conventional cone/ rod photoreceptors in the outer retina,*** results suggest that luminance encoding thalamic cells may participate in biological rhythmicity and /or unihemispheric sleep in birds.

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视黄酸受体基因在儿童胸腺中的表达

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复旦学报（医学版） 2003年第3期30卷 226-228,242,i002页

作者：周小建杨毅王卫平复旦大学附属儿科医院儿科研究所上海200032

目的观察视黄酸受体基因在儿童胸腺中的表达与分布,探讨其在儿童免疫系统发育中的意义。方法用地高辛素标记的反义RNA探针原位杂交法,测定5岁以下儿童胸腺中视黄酸受体RAR α、RAR β、RAR γ,RXR α、RXR β、RXR γ6种亚型基因的表... 详细信息

目的观察视黄酸受体基因在儿童胸腺中的表达与分布,探讨其在儿童免疫系统发育中的意义。方法用地高辛素标记的反义RNA探针原位杂交法,测定5岁以下儿童胸腺中视黄酸受体RAR α、RAR β、RAR γ,RXR α、RXR β、RXR γ6种亚型基因的表达与分布。同期的连续冰冻切片还用免疫组织化学法测定CD1a、CD3的表达,分析视黄酸受体基因表达及分布与T淋巴细胞成熟的关系,并采用实时定量RT-PCR法对基因表达水平进行定量分析。结果原位杂交结果显示,胸腺皮质及髓质均表达RAR α、RARγmRNA,而RXRα、RXR βmRNA主要在胸腺髓质表达,尤其在哈氏小体外周成熟的胸腺细胞表达较高。胸腺中不表达 RAR β、RXR γmRNA。实时定量 RT-PCR分析结果显示 RAR α、RXR α mRNA在出生后第一年高表达,1岁后表达下降,但在1～5岁之间变化无显著差异。RAR γmRNA则随年龄增长表达增高,RXR β mRNA在5岁以内变化不明显。结论视黄酸受体基因在胸腺的表达随儿童免疫系统的发育而变化,不同受体亚型基因表达水平的调节在T淋巴细胞的分化发育中可能具有重要意义。

关键词：基因表达水平胸腺视黄酸 RNA 受体基因儿童 T淋巴细胞 RXRα 实时定量髓质

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A promising approach for quantifying focal stroke modeling and assessing stroke progression:optical resolution photoacoustic microscopy photothrombosis

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Neural Regeneration Research 2025年第7期20卷 2029-2037页

作者： xiao Liang Xingping Quan xiaorui Geng Yujing Huang Yonghua Zhao Lei Xi Zhen Yuan Ping wang Bin Liu Faculty of Health Sciences University of MacaoMacao Special Administrative RegionChina Center for Cognitive and Brain Sciences University of MacaoMacao Special Administrative RegionChina Department of Biomedical Engineering Southern University of Science and TechnologyShenzhenGuangdong ProvinceChina State Key Laboratory of Quality Research in Chinese Medicine Institute of Chinese Medical SciencesUniversity of MacaoTaipaMacao Special Administrative RegionChina Department of Emergency Zhujiang HospitalSouthern Medical UniversityGuangzhouGuangdong ProvinceChina

To investigate the mechanisms underlying the onset and progression of ischemic stroke,some methods have been proposed that can simultaneously monitor and create embolisms in the animal cerebral ***,these methods often require complex systems and the effect of age on cerebral embolism has not been adequately studied,although ischemic stroke is strongly *** this study,we propose an optical-resolution photoacoustic microscopy-based visualized photothrombosis methodology to create and monitor ischemic stroke in mice simultaneously using a 532 nm pulsed *** observed the molding process in mice of different ages and presented age-dependent vascular embolism ***,we integrated optical coherence tomography angiography to investigate age-associated trends in cerebrovascular variability following a *** imaging data and quantitative analyses underscore the differential cerebrovascular responses to stroke in mice of different ages,thereby highlighting the technique's potential for evaluating cerebrovascular health and unraveling age-related mechanisms involved in ischemic strokes.

关键词： age-dependent cerebral cortex ischemic stroke mouse model optical coherence tomography angiography photoacoustic microscopy photothrombosis vascular imaging

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Electrode/Electrolyte Optimization‑Induced Double‑Layered Architecture for High‑Performance Aqueous Zinc‑(Dual)Halogen Batteries

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Nano-Micro Letters 2025年第3期17卷 121-137页

作者： Chengwang Zhou Zhezheng Ding Shengzhe Ying Hao Jiang Yan wang Timing Fang You Zhang Bing Sun xiao Tang xiaomin Liu School of Textiles and Clothing School of Chemistry and Chemical EngineeringQingdao UniversityQingdao 266071ShandongPeople’s Republic of China Centre for Clean Energy Technology School of Mathematical and Physical SciencesFaculty of ScienceUniversity of Technology SydneyUltimoNSW 2007Australia School of Chemistry and Chemical Engineering Henan Normal UniversityXinxiang 453007HenanPeople’s Republic of China

Aqueous zinc-halogen batteries are promising candidates for large-scale energy storage due to their abundant resources,intrinsic safety,and high theoretical ***,the uncontrollable zinc dendrite growth and spontaneous shuttle effect of active species have prohibited their practical ***,a double-layered protective film based on zinc-ethylenediamine tetramethylene phosphonic acid(ZEA)artificial film and ZnF2-rich solid electrolyte interphase(SEI)layer has been successfully fabricated on the zinc metal anode via electrode/electrolyte synergistic *** ZEA-based artificial film shows strong affinity for the ZnF2-rich SEI layer,therefore effectively suppressing the SEI breakage and facilitating the construction of double-layered protective film on the zinc metal *** double-layered architecture not only modulates Zn2+flux and suppresses the zinc dendrite growth,but also blocks the direct contact between the metal anode and electrolyte,thus mitigating the corrosion from the active *** employing optimized metal anodes and electrolytes,the as-developed zinc-(dual)halogen batteries present high areal capacity and satisfactory cycling *** work provides a new avenue for developing aqueous zinc-(dual)halogen batteries.

关键词： Zn metal anodes Double-layered protective film Electrode/electrolyte optimization Aqueous zinc-(dual)halogen batteries

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基于16SrRNA高通量测序的灰飞虱体内细菌群落结构及多样性分析

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昆虫学报 2018年第2期61卷 200-208页

作者：杨晓晴王正亮王天召俞晓平中国计量大学生命科学学院浙江省生物计量及检验检疫技术重点实验室杭州310018

【目的】探明灰飞虱Laodelphax striatellus体内细菌的群落结构和种类多样性。【方法】采用Illumina MiSeq测序平台对新羽化24 h的灰飞虱雌雄成虫体内细菌16S rRNA的V3-V4变异区序列进行高通量测序,应用USEARCH和Silva等软件和数据库来... 详细信息

【目的】探明灰飞虱Laodelphax striatellus体内细菌的群落结构和种类多样性。【方法】采用Illumina MiSeq测序平台对新羽化24 h的灰飞虱雌雄成虫体内细菌16S rRNA的V3-V4变异区序列进行高通量测序,应用USEARCH和Silva等软件和数据库来统计样品序列数目和操作分类单元(operational taxonomic unit,OTU)数量,分析灰飞虱雌雄成虫体内细菌的种类组成、丰度、Alpha多样性及其差异。【结果】灰飞虱雌、雄成虫样本分别获得29 333和25 919条有效序列,根据序列相似性进行聚类分析分别获得55和57个OTUs。其中,雌、雄成虫两类样本共有OTU数目20个,特有的OTU数目分别为35和37个。基于OTU物种分类分析,雌雄成虫样本中细菌种类一共覆盖7个门、15个纲、23个目、33个科、56个属和73个种。在门、纲、目和科分类阶元上,雌雄成虫两类样本均以变形菌门(Proteobacteria,雌99.96%/雄99.16%)、α-变形菌纲(Alphaproteobacteria,雌97.76%/雄97.84%)、红螺菌目(Rhodospirillales,雌83.92%/雄53.21%)和醋酸杆菌科(Acetobacteraceae,雌83.90%/雄53.17%)中的细菌为优势菌。在属分类阶元上,灰飞虱雌雄成虫体内优势菌为醋酸杆菌科未分类属(unclassified Acetobacteraceae),沃尔巴克氏体属Wolbachia次之,后者在雌、雄成虫体内丰度分别为13.81%和44.52%。在种水平上,灰飞虱雌、雄成虫体内特有细菌分别为21和32个种,但两类样本中性别特有种的丰度普遍极低,均不足0.5%。【结论】灰飞虱雌雄成虫间细菌群落组成和种类多样性存在差异。本研究为进一步挖掘灰飞虱体内关键微生物并解析其生物学功能及其利用等方面奠定了基础。

关键词：灰飞虱 16S rRNA 高通量测序细菌多样性

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