检索结果-南通市图书馆

Chinese Journal of Polymer Science 2024年第8期42卷 1147-1155页

作者： Wen-Jun Feng Yan-He Wu xiao-yang liu Zheng-Ke Wang MOE Key Laboratory of Macromolecular Synthesis and Functionalization Department of Polymer Science and EngineeringZhejiang UniversityHangzhou 310058China

Shear-thinning hydrogels have emerged for endoscopic submucosal dissection,while wound intervention after surgery has rarely been ***,a catechol-modified chitosa n hydrogel with shear-thinning property was developed for simultaneously facilitating endoscopic submucosal dissection and postoperative wound *** from the shear-thinning and self-healing characteristics,the asprepared hydrogel showed easily endoscopic *** also performed very well as submucosal cushion,which could remain above 70%after injection for 120 min in ex vivo porcine large intestine *** fact,the cushion height of normal saline dramatically decreased to 46%of the initial height at 30 *** nanoparticles encapsulated into the network endowed the hydrogel with almost reached 100%antibacterial effect against *** and *** hemolysis ratio of the hydrogel was calculated to be as low as 0.8%.Combined with good hemocompatibility and cytocompatibility,the as-prepared hydrogel displayed much higher in vivo wound closu re and healing efficacy than normal *** results demonstrated the superiority of the shear-thinning chitosan hydrogel in facilitating clinical endoscopic submucosal dissection surgery.

关键词： Shear-thinning hydrogel Endoscopic mucosal dissection Wound healing Catechol-modified chitosan Silver nanoparticles

Misdiagnosis of synovial sarcoma-cellular myofibroma with SRFRELA gene fusion:A case report

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Clinical Cases 2024年第7期12卷 1326-1332页

作者： Ying Zhou Yi-Wen Sun xiao-yang liu Dan-Hua Shen Department of Pathology Peking University People’s HospitalBeijing 100044China

BACKGROUND Cellular myofibroma is a rare subtype of myofibroma that was first described in *** diagnosis is often challenging because of its relative rarity,lack of known genetic abnormalities,and expression of muscle markers that can be confused with sarcomas that have myogenic ***,scholars have limited knowledge of this disease,and published cases are *** accumulation of diagnostic and treatment experiences is *** SUMMARY A 16-year-old girl experienced left upper limb swelling for 3 *** sought medical attention at a local hospital 10 months ago,where magnetic resonance imaging revealed a 5-cm soft tissue *** biopsy performed at a local hospital resulted in the diagnosis of a spindle cell soft tissue *** patient was referred to our hospital for limb salvage surgery with endoprosthetic *** was initially diagnosed with a synovial ***,clinical management with chemotherapy was continued for the malignant *** pathology department also performed fluorescence in situ hybridization for result validation,which returned negative for SS18 gene breaks,indicating that it was not a synovial ***-generation sequencing was used to identify the SRF-RELA *** final pathological diagnosis was a cellular/myofibroblastic neoplasm with an SRF-RELA gene *** patient had initially received two courses of chemotherapy;however,chemotherapy was discontinued after the final *** This case was misdiagnosed because of its rare occurrence,benign biological behavior,and pathological similarity to soft tissue sarcoma.

关键词： Cellular myofibroma SRF RELA Fusion Pathology Case report

High-sensitivity formaldehyde gas sensor based on Ce-doped urchin-like SnO_(2) nanowires derived from calcination of Sn-MOFs

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Frontiers of Materials Science 2024年第1期18卷 29-43页

作者： Wei xiao Wei yang Shantang liu Hubei Key Lab of Novel Reactor&Green Chemical Technology School of Chemistry and Environmental EngineeringWuhan Institute of TechnologyWuhan 430073China Hubei Key Laboratory of Wudang Local Chinese Medicine Research Department of ChemistrySchool of Pharmaceutical SciencesHubei University of MedicineShiyan 442000China

Metal-organic frameworks(MOFs)have attracted widespread attention due to their regular structures,multiple material centers,and various *** are always considered as one kind of ideal templates for developing highly sensitive and selective gas *** this study,the advantages of MOFs with the high specific surface area(71.9891 m^(2)·g^(-1))and uniform morphology were fully utilized,and urchin-like SnO_(2) nanowires were obtained by the hydrothermal method followed by the calcination using Sn-MOFs consisting of the ligand of C_(9)H_(6)O_(6)(H_(3)BTC)and Sn/Ce center ions as sacrificial *** unique urchin-like nanowire structure facilitated gas diffusion and adsorption,resulting in superior gas sensitivity.A series of Ce-doped SnO_(2) nanowires with different doping ratios were synthesized,and their gas sensing properties towards formaldehyde were *** resulted Ce-SnO_(2) was revealed to have high sensitivity(201.2 at 250℃),rapid response(4 s),long-term stability,and good repeatability for formaldehyde sensing,and the gas sensing mechanism of Ce-SnO_(2) exposed to formaldehyde was also systematically discussed.

关键词： Ce-SnO_(2) SnO_(2) gas sensor formaldehyde Sn-MOF

Active MoS_(2)-based electrode for green ammonia synthesis

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Journal of Chemical Engineering 2024年第1期65卷 268-275页

作者： Xin liu Lei yang Tao Wei Shanping liu Beibei xiao School of Energy and Power Engineering Jiangsu University of Science and TechnologyZhenjiang 212003China Institute Charles Gerhardt Montpellier UMR-5253Universite de MontpellierCNRSENSCMPlace E.Bataillon34095 Montpellier Cedex 05France

Nitrogen electro-reduction under mild conditions is one promising alternative approach of the energyconsuming Haber-Bosch process for the artificial ammonia *** critical aspect to unlocking this technology is to discover the catalysts with high selectivity and *** this work,the N_(2)-to-NH_(3)conversion on the functional MoS_(2)is fully investigated by density functional theory calculations since the layered MoS_(2)provides the ideal platform for the elaborating copies of the nitrogenase found in nature,wherein the functionalization is achieved via basal-adsorption,basal-substitution or edge-substitution of transition metal *** results reveal that the edge-functionalization is a feasible strategy for the activity promotion;however,the basal-adsorption and basal-substitution separately suffer from the electrochemical instability and the NRR ***,MoS_(2)functionalized via edge W-substitution exhibits an exceptional *** energetically favored reaction pathway is through the distal pathway and a limiting potential is less than 0.20 ***,this work escalates the rational design of the high-effective catalysts for nitrogen fixation and provides the explanation why the predicated catalyst have a good performance,paving the guidance for the experiments.

关键词： Nitrogen reduction reaction Density functional theory calculations Molybdenum disulfide Electrochemistry Catalyst Thermodynamics

3D robust anisotropic diffusion filtering algorithm for sparse view neutron computed tomography 3D image reconstruction

在线全文

学校读者我要写书评

暂无评论

Nuclear Science and Techniques 2024年第3期35卷 13-29页

作者： yang liu Teng-Fei Zhu Zhi Luo xiao-Ping Ouyang School of Nuclear Science and Engineering North China Electric Power UniversityBeijing 102206China State Key Laboratory of Nuclear Resources and Environment East China University of TechnologyNanchang 330013China State Key Laboratory of Intense Pulsed Radiation Simulation and Effect Xi’an 710024China

The most critical part of a neutron computed tomography(NCT) system is the image processing algorithm,which directly affects the quality and speed of the reconstructed *** types of noise in the system can degrade the quality of the reconstructed ***,to improve the quality of the reconstructed images of NCT systems,efficient image processing algorithms must be *** anisotropic diffusion filtering(ADF) algorithm can not only effectively suppress the noise in the projection data,but also preserve the image edge structure information by reducing the diffusion at the image ***,we propose the application of the ADF algorithm for NCT image *** compare the performance of different algorithms in NCT systems,we reconstructed images using the ordered subset simultaneous algebraic reconstruction technique(OS-SART) algorithm with different regular terms as image processing *** the iterative reconstruction,we selected two image processing algorithms,the Total Variation and split Bregman solved total variation algorithms,for comparison with the performance of the ADF ***,the filtered back-projection algorithm was used for comparison with an iterative *** reconstructing the projection data of the numerical and clock models,we compared and analyzed the effects of each algorithm applied in the NCT *** on the reconstruction results,OS-SART-ADF outperformed the other algorithms in terms of denoising,preserving the edge structure,and suppressing *** example,when the 3D Shepp–Logan was reconstructed at 25 views,the root mean square error of OS-SART-ADF was the smallest among the four iterative algorithms,at only *** universal quality index,mean structural similarity,and correlation coefficient of the reconstructed image were the largest among all algorithms,with values of 0.9877,0.9878,and 0.9887,respectively.

关键词： NCT OS-SART Sparse-view Anisotropic diffusion filtering

Primary ovarian angiosarcoma:Two case reports and review of literature

在线全文

学校读者我要写书评

暂无评论

World Journal of Clinical Cases 2023年第21期11卷 5122-5128页

作者： Ying Zhou Yi-Wen Sun xiao-yang liu Dan-Hua Shen Department of Pathology Peking University People’s HospitalBeijing 100044China

BACKGROUND Angiosarcoma(AS)is a rare and highly aggressive soft tissue disease that most commonly arises in deep soft *** are only a few reported cases of AS involving the ovary and even fewer reports of the underlying molecular ***,we briefly review two cases of primary ovarian AS(oAS)with specific molecular events and immune *** clinical features and prognosis of the disease,diagnosis,differential diagnosis,and new treatment approaches are discussed based on a literature *** SUMMARY Case 1:A 51-year-old female patient was admitted with right lower limb pain for 5 mo,and lower abdominal pain with hematuria for 1 *** removal of rectus abdominis muscle and fascia,partial hysterectomy,bilateral salpingooophorectomy,and inguinal and pelvic lymphadenectomy were *** revealed primary *** in situ hybridization revealed c-MYC gene ***+ADM+IFO+DTIC(MAID)regimen was administered,but stable disease was *** patient died 1 mo *** 2:A 41-year-old female patient presented with fatigue,nausea,decreased appetite,and diffuse abdominal *** physical examination,the abdomen was distended and a complex cystic mass was palpable in the right pelvic *** revealed primary *** chemotherapy was administered and programmed death ligand 1(PD-L1)staining was performed on the tumor *** patient benefited from anti-PD-1 immunotherapy and is alive without any evidence of disease 27 mo off therapy in *** Long-term survival benefit for primary oAS can be achieved by alternative therapeutic strategies using pathological indicators to inform treatment.

关键词： Primary angiosarcoma Ovarian Therapy Diagnosis Prognosis Case report

In-situ additive manufacturing of high strength yet ductility titanium composites with gradient layered structure using N_(2)

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

International Journal of Extreme Manufacturing 2024年第3期6卷 387-409页

作者： Yunmian xiao Changhui Song Zibin liu Linqing liu Hanxiang Zhou Di Wang Yongqiang yang School of Mechanical and Automotive Engineering South China University of TechnologyGuangzhou 510641People’s Republic of China

It has always been challenging work to reconcile the contradiction between the strength and plasticity of titanium *** powder bed fusion(LPBF) is a convenient method to fabricate innovative composites including those inspired by gradient layered *** this work,we used LPBF to selectively prepare Ti N/Ti gradient layered structure(GLSTi)composites by using different N_(2)–Ar ratios during the LPBF *** systematically investigated the mechanisms of in-situ synthesis Ti N,high strength and ductility of GLSTi composites using microscopic analysis,TEM characterization,and tensile testing with digital image ***,a digital correspondence was established between the N_(2) concentration and the volume fraction of LPBF in-situ synthesized Ti *** results show that the GLSTi composites exhibit superior mechanical properties compared to pure titanium fabricated by LPBF under pure ***,the tensile strength of GLSTi was more than 1.5times higher than that of LPBF-formed pure titanium,reaching up to 1100 MPa,while maintaining a high elongation at fracture of 17%.GLSTi breaks the bottleneck of high strength but low ductility exhibited by conventional nanoceramic particle-strengthened titanium matrix composites,and the hetero-deformation induced strengthening effect formed by the Ti N/Ti layered structure explained its strength-plasticity balanced *** microhardness exhibits a jagged variation of the relatively low hardness of 245 HV0.2 for the pure titanium layer and a high hardness of 408 HV0.2 for the N_(2) in-situ synthesis *** study provides a new concept for the structure-performance digital customization of 3D-printed Ti-based composites.

关键词： laser powder bed fusion layered structure composites in-situ synthesis TiN strength-plasticity synergy

Two-thiols-regulated fabrication of plasmonic nanoparticles with co-enhanced Raman scattering and circular dichroism responses

在线全文

学校读者我要写书评

暂无评论

Rare Metals 2023年第11期42卷 3673-3681页

作者： Jia-Qi Chen Han-Bo Li Xi Lu xiao-yang liu Wei Feng Pan Wang Jian-Qiang Zhao Zhen-Yu Zhu Guang-Chao Zheng xiao-Chun Wu School of Mechanical Engineering Chengdu UniversityChengdu610000China CAS Key Laboratory of Standardization and Measurement for Nanotechnology CASNational Center for Nanoscience and TechnologyBeijing100190China University of the Chinese Academy of Sciences Beijing100049China Innovation Research Center of Chiral Drugs Institute for Advanced StudyChengdu UniversityChengdu610106China School of Physics and Microelectronics Key Laboratory of Material PhysicsMinistry of EducationZhengzhou UniversityZhengzhou450001China Institute of Quantum Materials and Physics Henan Academy of SciencesZhengzhou450046China

Plasmonicnanoparticles(PNPs)with stable nanogaps are important to achieve strong,uniform and quantitative gap-enhanced Raman scattering(GERS)*** PNPs with plasmonic circular dichroism(PCD)responses have been discovered to be suitable for applications in enantiomeric recognition,cancer therapy and activation of immune ***,two-thiolsmodulated growth was demonstrated to result in the acquisition of PNPs with synergistically enhanced GERS and PCD signals.4-Aminothiophenol(4-ATP)and cysteine(Cys)played the role of Raman reporter and chiral stimulus,*** a fixed 4-ATP concentration,the GERS signal of PNPs was significantly enhanced with the increase of the concentration of ***,at a fixed concentration of Cys,an increase in PCD response was observed by elevating the concentration of *** aforementioned molecules acted as morphology controllers,leading to the formation of helical *** is suggested that the giant GERS and PCD response were contributed by the‘‘hot spots''within the PNPs and more perfect helical *** research pointed out a novel synthetic guideline to obtain PNPs with multiple functionalities by incorporating multi-ligands into the growth stages.

关键词： Gap-enhanced Raman scattering(GERS) Chirality Thiol Plasmonic nanoparticles

Three-stage niobium mineralization at Bayan Obo, China

在线全文

学校读者我要写书评

暂无评论

National Science Review 2024年第4期11卷 102-110页

作者： Yan Yu yang Li Yu liu xiao-xiao Ling Li-Guang Wu Li yang Lan yang Bo yang Yong-Gang Zhao Xian-Hua Li State Key Laboratory of Lithospheric Evolution Institute of Geology and Geophysics Chinese Academy of Sciences College of Earth and Planetary Science University of Chinese Academy of Sciences Ministry of Education Key Laboratory of Orogenic Belts and Crustal Evolution School of Earth and Space SciencesPeking University Mining Research Institute Baotou Iron and Steel(Group) Co.LTD State Key Laboratory of Baiyunobo Rare Earth Resource Research and Comprehensive Utilization

The Chinese Bayan Obo deposit is a world-class rare earth element(REE) deposit with considerable niobium(Nb) and iron(Fe) resources. A complete genetic understanding on all metals is fundamental for establishing genetic models at Bayan Obo. With extensive research being focused on REE enrichment, the timing and controls of Nb enrichment remain unresolved at Bayan Obo, which is mainly due to the challenges in dating, i.e. multistage thermal events, fine-grained minerals with complex textures and the rare occurrence of uranium-enriched minerals with mature dating methods. Based on robust geological and petrographic frameworks, here we conducted ion probe uranium-lead(U-Pb) dating of ferrocolumbite to unravel the timing, hence the genesis of Nb mineralization. Three types of hydrothermal ferrocolumbites—key Nb-bearing minerals—are identified based on their textures and mineral assemblages. They yield U-Pb ages of 1312 ± 47 Ma(n = 99), 438 ± 7 Ma(n = 93), and 268 ± 5 Ma(n = 19), respectively. In line with deposit geology, we tentatively link the first, second and third stage Nb mineralization to Mesoproterozoic carbonatite magmatism, ubiquitous early Paleozoic hydrothermal activity, and Permian granitic magmatism, respectively. While quantifying the contribution of metal endowment from each stage requires further investigation, our new dates highlight that multi-stage mineralization is critical for Nb enrichment at Bayan Obo, which may also have implications for the enrichment mechanism of Nb in REE deposits in general.

关键词： niobium mineralization U-Pb dating ferrocolumbite Bayan Obo

Deep insight into the B-cell associated tertiary lymphoid structure and tumor immunotherapy

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Cancer Biology & Medicine 2024年第2期21卷 125-131页

作者： Jilong yang Jin Xu Haotian liu Wanyi xiao Gengpu Zhang Department of Bone and Soft Tissue Tumor Tianjin Medical University Cancer Institute&HospitalNational Clinical Research Center for CancerKey Laboratory of Cancer Prevention and TherapyTianjinTianjin’s Clinical Research Center for CancerKey Laboratory of Molecular Cancer EpidemiologyTianjin 300060China Department of Anaesthesiology Tianjin University Tianjin HospitalTianjin 300211China

Bod et al.1 recently published a study in Nature that garnered attention to B cell-associated anti-tumor immunity and immunotherapy of melanoma and other *** a promising supplemental immunotherapy to mainstream method... 详细信息

关键词： immunotherapy immunity