检索结果-南通市图书馆

Research progress in CALPHAD assisted metal additive manufacturing

在线全文

学校读者我要写书评

暂无评论

China Foundry 2024年第4期21卷 295-310页

作者： Ya-qing Hou xiao-qun li Wei-dong Cai Qing Chen Wei-ce Gao Du-peng He Xue-hui Chen Hang Su China Iron&Steel Research Institute Group Beijing 100081China Thermo-Calc Software AB SolnaSE-169Sweden KTH Royal Institute of Technology StockholmSE-100Sweden Central Iron and Steel Research Institute Beijing 100081China

Metal additive manufacturing(MAM)technology has experienced rapid development in recent *** both equipment and materials progress towards increased maturity and commercialization,material metallurgy technology based on high energy sources has become a key factor influencing the future development of *** calculation of phase diagrams(CALPHAD)is an essential method and tool for constructing multi-component phase diagrams by employing experimental phase diagrams and Gibbs free energy models of simple *** combining with the element mobility data and non-equilibrium phase transition model,it has been widely used in the analysis of traditional metal *** development of CALPHAD application technology for MAM is focused on the compositional design of printable materials,the reduction of metallurgical imperfections,and the control of microstructural *** endeavor carries considerable theoretical and practical *** paper summarizes the important achievements of CALPHAD in additive manufacturing(AM)technology in recent years,including material design,process parameter optimization,microstructure evolution simulation,and properties ***,the limitations of applying CALPHAD technology to MAM technology are discussed,along with prospective research directions.

关键词： metal additive manufacturing CALPHAD integrated computational material engineering powder bed fusion material design microstructure simulation

CT-based radiomics to predict development of macrovascular invasion in hepatocellular carcinoma:A multicenter study

在线全文

学校读者我要写书评

暂无评论

Hepatobiliary & Pancreatic Diseases International 2022年第4期21卷 325-333页

作者： Jing-Wei Wei Si-Rui Fu Jie Zhang Dong-Sheng Gu xiao-qun li Xu-Dong Cheng Shuai-Tong Zhang xiao-Fei He Jian-Feng Yan li-Gong Lu Jie Tian Key Laboratory of Molecular Imaging Institute of AutomationChinese Academy of SciencesBeijing 100190China Beijing Key Laboratory of Molecular Imaging Beijing 100190China University of Chinese Academy of Sciences Beijing 100049China Zhuhai Interventional Medical Center Zhuhai Precision Medical CenterZhuhai People’s HospitalZhuhai Hospital of Jinan UniversityZhuhai 519000China Department of Radiology Zhuhai Precision Medical CenterZhuhai People’s HospitalZhuhai Hospital of Jinan UniversityZhuhai 519000China Department of Interventional Treatment Zhongshan City People’s HospitalZhongshan 528400China Department of Radiology Shenzhen People’s HospitalShenzhen 518000China Interventional Diagnosis and Treatment Department Nanfang HospitalSouthern Medical UniversityGuangzhou510000China Department of Radiology Yangjiang People’s HospitalYangjiang 529500China Beijing Advanced Innovation Center for Big Data-Based Precision Medicine School of Medicine and EngineeringBeihang UniversityBeijing 100191China Engineering Research Center of Molecular and Neuro Imaging of Ministry of Education School of Life Science and TechnologyXidian UniversityXi’an 710126China

Background:Macrovascular invasion(MaVI)occurs in nearly half of hepatocellular carcinoma(HCC)patients at diagnosis or during follow-up,which causes severe disease deterioration,and limits the possibility of surgical *** study aimed to investigate whether computed tomography(CT)-based radiomics analysis could help predict development of MaVI in ***:A cohort of 226 patients diagnosed with HCC was enrolled from 5 hospitals with complete MaVI and prognosis ***-based radiomics signature was built via multi-strategy machine learning ***,MaVI-related clinical factors and radiomics signature were integrated to construct the final prediction model(CRIM,clinical-radiomics integrated model)via random forest ***-regression analysis was used to select independent risk factors to predict the time of MaVI ***-Meier analysis was conducted to stratify patients according to the time of MaVI development,progression-free survival(PFS),and overall survival(OS)based on the selected risk ***:The radiomics signature showed significant improvement for MaVI prediction compared with conventional clinical/radiological predictors(Plidation(n=72)datasets,*** presented with excellent generalization with AUC of 0.956,1.000,and 1.000 in each external cohort that accepted disparate CT scanning protocol/***9_fos_InterquartileRange[hazard ratio(HR)=1.98;Plications.

关键词： Hepatocellular carcinoma Macrovascular invasion Radiomics Computed tomography Prognosis

Percutaneous microwave ablation and transcatheter arterial chemoembolization for serum tumor markers and prognostics of middle-late primary hepatic carcinoma

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastrointestinal Surgery 2023年第12期15卷 2783-2791页

作者： Zhi-Peng lin Da-Bei Huang Xu-Gong Zou Yuan Chen xiao-qun li Jian Zhang Department of Interventional Medicine Zhongshan People’s HospitalZhongshan 528400Guangdong ProvinceChina

BACKGROUND Primary hepatic carcinoma(PHC)has an insidious onset and is usually diagnosed in the middle and late *** transcatheter arterial chemoembolization(TACE)is the preferred option for treating middle-and advanced-stage PHC,it has limited efficacy in killing tumor cells and poor long-term *** plus percutaneous microwave coagulation therapy(PMCT)is more effective than interventional therapy alone and can improve survival ***,there are few reports on the effects of TACE and PMCT on serum marker levels and the prognosis of patients with advanced *** To investigate the effect of PMCT+TACE on serum tumor markers and the prognosis of middle-late *** This retrospective study included 150 patients with middle-late PHC admitted to Zhongshan People’s Hospital between March 2018 and February *** were divided into a single group(treated with TACE,n=75)and a combined group(treated with TACE+PMCT,n=75).Before and after treatment,the clinical efficacy and serum tumor marker levels[carbohydrate antigen 19-9(CA19-9),alpha-fetoprotein(AFP),and carcinoembryonic antigen(CEA)]of both groups were *** 1-year survival rates and prognostic factors of the two groups were *** The combined group had 21 and 35 cases of complete remission(CR)and partial remission(PR),*** single group had 13 and 25 cases of CR and PR,decreased,with the decrease in the combined group being more significant(P<0.05).The 1-year survival rate of the combined group(80.00%)was higher than that of the single group(60.00%)(P<0.05).The average survival time within 1 year in the combined group was 299.38±61.13 d,longer than that in the single group(214.41±72.97 d,P<0.05).COX analysis revealed that tumor diameter,tumor number,and the treatment method were prognostic factors for patients with middle-late PHC(P<0.05).CONCLUSION TACE+PMCT is effective in treating patients with mid-late *** reduces the levels of tumor markers,prolongs

关键词： Middle-late primary hepatic carcinoma Percutaneous microwave coagulation therapy Transcatheter arterial chemoembolization Effect Tumor markers Prognosis Survival

Efficacy and safety of targeted therapy plus immunotherapy combined with hepatic artery infusion chemotherapy (FOLFOX) for unresectable hepatocarcinoma

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2024年第17期30卷 2321-2331页

作者： Zhi-Peng lin xiao-Long Hu Du Chen Da-Bei Huang Xu-Gong Zou Hai Zhong Sheng-Xiang Xu Yuan Chen xiao-qun li Jian Zhang Department of Interventional Medicine Zhongshan People’s HospitalZhongshan 528400Guangdong ProvinceChina

BACKGROUND The advent of cutting-edge systemic therapies has driven advances in the treatment of hepatocellular carcinoma(HCC),and therapeutic strategies with multiple modes of delivery have been shown to be more efficacious than ***,the mechanisms underlying this innovative treatment modality have not been *** To evaluate the clinical efficacy of targeted therapy plus immunotherapy combined with hepatic arterial infusion chemotherapy(HAIC)of FOLFOX in patients with unresectable *** We enrolled 53 patients with unresectable HCC who received a combination of targeted therapy,immunotherapy,and HAIC of FOLFOX between December 2020 and June 2021 and assessed the efficacy and safety of the treatment *** The objective response rate was 60.4%(32/53),complete response was 24.5%(13/53),partial response was 35.9%(19/53),and stable disease was 39.6%(21/53).The median duration of response and median progression-free survival were 9.1 and 13.9 months,*** surgical conversion rate was 34.0%(18/53),and 1-year overall survival was 83.0%without critical complicating diseases or adverse events(AEs).CONCLUSION The regimen of HAIC of FOLFOX,targeted therapy,and immunotherapy was curative for patients with unresectable HCC,with no serious AEs and a high rate of surgical conversion.

关键词： Hepatocellular carcinoma Hepatic arterial infusion chemotherapy Targeted therapy Immunotherapy Adverse events

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

聚丙烯耐划伤性能的研究

塑料工业 2015年第11期43卷 142-146页

作者：肖利群重庆科聚孚工程塑料有限责任公司重庆401332 中煤科工集团重庆研究院有限公司重庆401332

研究了填料(不同粒径的滑石粉、超细活性碳酸钙、云母粉、空心玻璃微珠)、增韧剂(乙烯基弹性体POE、三元乙丙橡胶EPDM)、耐划伤助剂、产品的表面形态对聚丙烯的(PP)耐划伤性能的影响。结果表明,随着填料含量的增加,色差(ΔE)增大,PP的... 详细信息

研究了填料(不同粒径的滑石粉、超细活性碳酸钙、云母粉、空心玻璃微珠)、增韧剂(乙烯基弹性体POE、三元乙丙橡胶EPDM)、耐划伤助剂、产品的表面形态对聚丙烯的(PP)耐划伤性能的影响。结果表明,随着填料含量的增加,色差(ΔE)增大,PP的耐划伤性能下降;当滑石粉和超细活性碳酸钙的质量分数是25%时,PP的ΔE增大了3倍,PP的耐划伤性能急剧下降。滑石粉的目数越高,ΔE越小,耐划伤性能越好;滑石粉(3 000目)、超细活性碳酸钙的效果最好。POE、EPDM的加入使PP的耐划伤性能下降,而且其添加量越大,耐划伤性能越差。耐划伤助剂能有效改善PP的耐划伤性。产品的表面形态对PP的耐划伤性能影响很大,皮纹越大、越深,PP的耐划伤性能越差。

关键词：聚丙烯耐划伤性能表面形态填料增韧剂

在线全文

学校读者我要写书评

暂无评论

汽车用PA6/ABS带色合金材料的研究

塑料工业 2017年第5期45卷 133-137页

作者：肖利群中煤科工集团重庆研究院有限公司重庆400039 重庆科聚孚工程塑料有限责任公司重庆401332

选用聚酰胺(PA6)、丙烯腈-丁二烯-苯乙烯共聚物(ABS)高胶粉和相容剂,制备了PA6/ABS合金材料。研究了ABS用量对PA6/ABS合金材料加工性能和力学性能的影响。结果表明,ABS含量不同,挤出状态不同;ABS含量越高材料的流动性越差;随着ABS含量... 详细信息

选用聚酰胺(PA6)、丙烯腈-丁二烯-苯乙烯共聚物(ABS)高胶粉和相容剂,制备了PA6/ABS合金材料。研究了ABS用量对PA6/ABS合金材料加工性能和力学性能的影响。结果表明,ABS含量不同,挤出状态不同;ABS含量越高材料的流动性越差;随着ABS含量的降低,材料的拉伸强度依次升高,悬臂梁冲击强度和热变形温度呈不同的变化规律。选择PA6∶ABS=70∶25配方,对比不同抗氧剂时带色材料经热氧老化后颜色的变化及色粉含量增加后颜色的变化。结果表明,受阻酚类抗氧剂(1010)和硫醚类抗氧剂(DLTP)的复合抗氧体系和抗氧剂H10对抑制PA6/ABS合金材料热氧老化后的颜色黄变有很好的作用;通过添加钛白粉来增加色粉的含量可以明显降低材料经热氧老化后的颜色变化率,1010和DLTP的复合抗氧体系较抗氧剂H161能更好地抑制PA6/ABS合金材料热氧老化后C—N键的断裂和生色基团羰基的产生。研制的灰色PA6/ABS合金材料已应用于汽车儿童座椅配件。

关键词：聚酰胺6 丙烯腈-丁二烯-苯乙烯高胶粉热氧老化抗氧剂颜色

在线全文

学校读者我要写书评

暂无评论

台山核电厂海水库和排水池开挖爆破

爆破 2013年第1期30卷 63-65,109页

作者：肖力群深圳市安托山投资发展有限公司深圳518040

广东省台山核电厂海水库、排水池开挖工程是台山核电厂配套工程项目,工期仅6个月需爆破石方工程量7.8×105m3,工程质量要求高,且局部地段爆区环境复杂,要严控爆破震动。应用不同钻孔直径的浅孔与深孔相结合的控制爆破以及静态破碎剂胀... 详细信息

广东省台山核电厂海水库、排水池开挖工程是台山核电厂配套工程项目,工期仅6个月需爆破石方工程量7.8×105m3,工程质量要求高,且局部地段爆区环境复杂,要严控爆破震动。应用不同钻孔直径的浅孔与深孔相结合的控制爆破以及静态破碎剂胀裂破碎的综合开挖技术,分地段采取不同的爆破方案,采用复合起爆网路,配合大功率挖掘机开挖作业,在工期紧的情况下安全高效保质保量保工期地完成了该工程项目的开挖任务,取得良好的爆破效果、工程效益和显著的经济效益。

关键词：爆破开挖控制爆破复式起爆网路静态破碎

高速光纤通信数据传输中的大数据合理调度模型设计

在线全文

学校读者我要写书评

暂无评论

激光杂志 2016年第5期37卷 112-116页

作者：肖利群四川工商学院成都611745

为了提升高速光纤通信数据传输的速率,保证光纤网络通信数据吞吐量的稳定性。设计一种大数据合理调度模型,将丢包率最小作为目标,引入激励机制中的贡献思想设计光纤通信数据传输中大数据合理调度模型。给出了高速光纤通信网络拓扑,并对... 详细信息

为了提升高速光纤通信数据传输的速率,保证光纤网络通信数据吞吐量的稳定性。设计一种大数据合理调度模型,将丢包率最小作为目标,引入激励机制中的贡献思想设计光纤通信数据传输中大数据合理调度模型。给出了高速光纤通信网络拓扑,并对参数进行设置。依次进行了往返时延的仿真分析、平均传输速率分析和吞吐量稳定性分析实验,分析实验结果得出的结论如下:采用本文模型对大数据进行调度时,两条路径的往返时延较为接近,通过不同路径对数据进行传输到达接收端的时延差较小,进行数据调度后数据传输的速率较单路传输速率更低,本文模型对带宽的变化具有很好的适应性;本文模型的吞吐量稳定性和于调度轮转模型。

关键词：高速光纤通信数据大数据调度模型设计

超高效液相色谱法同时测定面制品中的防霉剂和多种防腐剂

在线全文

学校读者我要写书评

暂无评论

食品工业 2015年第6期36卷 288-290页

作者：肖立群广东省安全生产技术中心广州510000

研究了超高效液相色谱法同时测定面制品中的富马酸二甲酯、山梨酸、对羟基苯甲酸乙酯、对羟基苯甲酸丙酯、对羟基苯甲酸丁酯和对羟基苯甲酸戊酯分析方法,以Waters ACQUITY UPLCTMBEH C18(50 mm×2.1mm,1.7μm)柱为分离柱,以流动相为0.1... 详细信息

研究了超高效液相色谱法同时测定面制品中的富马酸二甲酯、山梨酸、对羟基苯甲酸乙酯、对羟基苯甲酸丙酯、对羟基苯甲酸丁酯和对羟基苯甲酸戊酯分析方法,以Waters ACQUITY UPLCTMBEH C18(50 mm×2.1mm,1.7μm)柱为分离柱,以流动相为0.1%甲酸水溶液-甲醇进行梯度洗脱,采用二极管阵列在210 nm和260 nm进行检测,整个分离过程在4.50 min内完成,6种组分在0.312 5~10μg/m L浓度范围内的线性关系良好,方法检出限分别为0.019 5,0.002 2,0.019 6,0.026 1,0.046 4和0.360μg/g,样品加标回收率为81.36%~103.10%;相对标准偏差为0.41%~8.40%,该方法简单,分离效果好,分析时间短,能够满足大量日常面制品中防霉剂和防腐剂的检测需要。

关键词：超高效液相色谱防霉剂防腐剂面制品