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Fluid Model Modulated by an M/M/1 Working Vacation Queue with Negative Customer

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Acta Mathematicae Applicatae Sinica 2018年第2期34卷 404-415页

作者： Xiu-li XU Xian-ying WANG xiao-feng SONG xiao-qing li College of Science Yanshan University

This paper investigates a fluid model driven by an M/M/1 queue with working vacations and RCE （Removal of customer in the end） policy of negative customer. In the external environment, the negative customer is not served by the server and only removes the positive customer in the end one-to-one. We establish a fluid flow model based on this stochastic process, and obtain the mean buffer content and the probability of empty buffer for this fluid queue using the LT （Laplace transform） method. Moreover, several special cases of the model here are obtained. Finally, some numerical examples are presented to demonstrate the effects of parameters on the performance indices of the fluid model.

关键词： fluid model negative customer RCE (Removal of customer in the end) policy buffer content LT(Laplace transform)

Flexible Robotic Grasping Strategy with Constrained Region in Environment

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International Journal of Automation and computing 2017年第5期14卷 552-563页

作者： Chao Ma Hong Qiao Rui li xiao-qing li School of Automation and Electrical Engineering University of Science and Technology Beijing State Key Laboratory of Management and Control for Complex Systems Institute of AutomationChinese Academy of Sciences

Grasping is a significant yet challenging task for the robots. In this paper, the grasping problem for a class of dexterous robotic hands is investigated based on the novel concept of constrained region in environment, which is inspired by the grasping operations of the human beings. More precisely, constrained region in environment is formed by the environment, which integrates a bio-inspired co-sensing framework. By utilizing the concept of constrained region in environment, the grasping by robots can be effectively accomplished with relatively low-precision sensors. For the grasping of dexterous robotic hands, the attractive region in environment is first established by model primitives in the configuration space to generate offline grasping planning. Then, online dynamic adjustment is implemented by integrating the visual sensory and force sensory information, such that the uncertainty can be further eliminated and certain compliance can be obtained. In the end, an experimental example of BarrettHand is provided to show the effectiveness of our proposed grasping strategy based on constrained region in environment.

关键词： Grasping strategy compliant grasping dexterous robotic hands attractive region in environment constrained region inenvironment.

A new trimeric furanocoumarin from Heracleum rapula

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Chinese Chemical Letters 2009年第9期20卷 1088-1090页

作者： Cun Zhang YuanYan liu Yong qing xiao li li Institute of Chinese Materia Medica China Academy of Traditional Chinese Medicine Beijing 100700 China

A new trimeric linear-type furanocoumarin, rapultririn A （1）, was isolated from the underground part ofHeracleum rapula. The structure of this new compound was elucidated by NMR, MS spectroscopic methods. 2009 Yon... 详细信息

关键词： Heracleum rapula Tricoumarin Rapultririn A

Solvent Effect on Conformation of a Cycloheptapeptide,Stylopeptide 1,Evaluated by Molecular Dynamics in Methonal and Aqueous Environments

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Chemical Research in Chinese Universities 2009年第4期25卷 560-563页

作者： liU xiao-qing li xiao-hui TENG Hu XIU Zhi-long Department of Bioscience and Biotechnology School of Environmental and Biological Science and Technology Dalian University of Technology Dalian 116024 P. R. China

Stylopeptide 1 synthesized and isolated from different sources exhibits a large activity difference in inhibitory effect on the growth of a cancer *** on the different amounts of methanol and water during synthesis,isolation and purification of the cyclic peptides,molecular dynamics(MD) was employed to simulate the conformation of stylopeptide 1 in methanol and aqueous *** comparative results show that the backbone ring was more rigid in methanol than in *** methanol,two β-turns and three hydrogen bonds were well conserved throughout the simulation,whereas no hydrogen bonds or turns were preserved in *** activity difference of stylopeptide 1 seemed to be attributed to the solvent effect on its conformation.

关键词： Cyclic peptide Methanol Water Molecular dynamics

Two new glycosides from the seeds of Cassia obtusifolia

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Chinese Chemical Letters 2009年第9期20卷 1097-1099页

作者： Cun Zhang Gui liu li Yong qing xiao li li Zhen Pang Institute of Traditional Chinese Materia Madica Chinese Academy of Chinese Medical Sciences Beijing 100700 China

Two new glycosides, nor-rubrofusadn-6-O-β-D-（6＇-O-acetyl）glucopyranoside （1） and 1-desmethylaurantio-obtusin-2-O-β-D- glucopyranoside （2） were isolated from the seeds of Cassia obtusifolia and their structures were established by chemical and spectral evidences. 2009 Yong qing xiao. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved.

关键词： Cassia obtusifolia Nor-rubrofusarin-6-O-β-D-(6'-O-acetyl)glucopyranoside 1-Desmethylaurantio-obtusin-2-O-β-D-glucopyranoside

Antipsychotics cardiotoxicity:What's known and what's next

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World Journal of Psychiatry 2021年第10期11卷 736-753页

作者： xiao-qing li Xin-Ru Tang li-liang li Department of Forensic Medicine School of Basic Medical SciencesFudan UniversityShanghai 200032China

Chronic use of antipsychotic medications entails a dilemma between the benefit of alleviating psychotic symptoms and the risk of troubling,sometimes lifeshortening adverse ***-induced cardiotoxicity is one of the most life-threatening adverse effects that raises widespread *** cardiotoxic effects range from arrhythmia to heart failure in the clinic,with myocarditis/cardiomyopathy,ischemic injuries,and unexplained cardiac lesions as the pathological *** mechanisms have been proposed to underlie antipsychotic *** review aims to summarize the clinical signs and pathological changes of antipsychotic cardiotoxicity and introduce recent progress in understanding the underlying mechanisms at both the subcellular organelle level and the molecular *** also provide an up-to-date perspective on future clinical monitoring and therapeutic strategies for antipsychotic *** propose that third-generation antipsychotics or drug adjuvant therapy,such as cannabinoid receptor modulators that confer dual benefits—i.e.,alleviating cardiotoxicity and improving metabolic disorders—deserve further clinical evaluation and marketing.

关键词： Antipsychotics Cardiotoxicity Sudden cardiac deaths Cannabinoid receptor Adrenoceptor

Spontaneous resolution of idiopathic intestinal obstruction after pneumonia: A case report

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World Journal of Clinical Cases 2020年第19期8卷 4512-4520页

作者： Bing-qing Zhang xiao-Yan Dai Qiu-Yue Ye Long Chang Zhi-Wei Wang xiao-qing li Yong-Ning li Internal Medicine Peking Union Medical College HospitalChinese Academy of Medical Science and Peking Union Medical CollegeBeijing 100730China International Medical Services Peking Union Medical College HospitalChinese Academy of Medical Science and Peking Union Medical CollegeBeijing 100730China Interventional Section Department of RadiologyPeking Union Medical College HospitalChinese Academy of Medical Science and Peking Union Medical CollegeBeijing 100730China Department of Gastroenterology Peking Union Medical College HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100730China Department of Neurosurgery Peking Union Medical College HospitalChinese Academy of Medical Science and Peking Union Medical CollegeBeijing 100730China

BACKGROUND Duodenal obstruction is a common clinical scenario that can either be mechanical or a *** management of intestinal obstruction starts from localization and proceeds to histological examination of the stenotic *** factors and dysfunction of distant organs might contribute to the development of intestinal ***,we report a unique case of idiopathic mechanical duodenal obstruction,which resolved spontaneously after 3 mo of conservative treatment,but was followed by intestinal *** SUMMARY An 84-year-old woman presented with worsened postprandial vomiting accompanied by prolonged *** noninvasive investigations revealed complete circumferential stenosis in the descending duodenum without known *** surgery was postponed due to septic shock and possible pulmonary fungal *** treatment for 3 mo for ileus and control of pulmonary infection resolved the intestinal obstruction ***,2 wk later,she had regurgitation and postprandial vomiting again,complicated by deteriorating wheezing and *** tomography revealed a dilated stomach and proximal duodenum without new intestinal stricture or pulmonary *** patient fully recovered after combined treatment with antireflux agents,enema,prokinetics,and *** This complicated case highlights the inter-relationship of local and systemic contributions to ileus and gut dysfunction,which requires multidisciplinary treatment.

关键词： Duodenal obstruction Pseudo-intestinal obstruction Pneumonia Airway hyperresponsiveness Multidisciplinary treatment Case report

Ethnic differences in genetic polymorphism associated with irritable bowel syndrome

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World Journal of Gastroenterology 2020年第17期26卷 2049-2063页

作者： Qi-Yun xiao Xiu-Cai Fang xiao-qing li Gui-Jun Fei Department of Gastroenterology Peking Union Medical College HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100730China

Genetic polymorphism is associated with irritable bowel syndrome(IBS)in terms of susceptibility and clinical *** studies have shown that genetic polymorphism might play a key role in the onset and progression of IBS by modulating components of its pathogenesis such as the gut-brain axis,gastrointestinal motility,inflammatory activity,and immune *** underlying pathophysiological mechanisms have not been fully clarified,the potential ethnic differences that are present in worldwide genetic studies of IBS deserve *** review surveyed numerous studies focusing on IBSassociated single nucleotide polymorphisms,and investigated the ethnic disparities revealed by *** results demonstrate the need for more attention on ethnic factors in IBS-related genetic *** ethnic backgrounds into accounts and placing emphasis on disparities potentially ascribed to ethnicity could help lay a solid and generalized foundation for transcultural,multi-ethnic,or secondary analyses in IBS,for example,a *** genetic studies considering ethnic factors are greatly needed to obtain a better understanding of the pathophysiological mechanisms of IBS and to improve the prevention,intervention,and treatment of this disease.

关键词： Irritable bowel syndrome Ethnicity Genetic polymorphism Single nucleotide polymorphism Genome-wide association Pathogenesis

A new phenanthraquinone from the roots of Peucedanum praeruptorum

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Chinese Chemical Letters 2010年第7期21卷 816-817页

作者： Cun Zhang li li Yong qing xiao Wen li xiao Jie Yin Guo Fang Tian Dong Dong Chen Yun Wang Institute of Chinese Materia Madica China Academy of Traditional Chinese MedicineBeijing 100700China

A new compound,9,10-dihydrophenanthrinic acid,9,10-dione-3,4-methylenedioxy-8-methoxy（1） was isolated from the roots of Peucedanum praeruptorum Dunn on the basis of spectral evidences.

关键词： Peucedanum praeruptorum 9 10-Phenanthraquinone 9 10-Dihydrophenanthrinic acid 9 10-Dione-3 4-methylenedioxy-8-methoxy