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Zircon U-Pb geochronologic,geochemical and Sr-Nd-Pb isotope characteristics of the Beidaban granites in the North Qilian Orogenic Belt:Petrogenesis and tectonic implications

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Acta Geochimica 2024年第6期43卷 1087-1104页

作者： Tao Yang Zhi-yuan Sun Ming-liang Wang xiao-qiang zhu Jing-yu Zhao The First Institute of Geology and Mineral Exploration Gansu Provincial Bureau of Geology and Mineral ExplorationTianshui 741020China School of Resources and Civil Engineering Suzhou UniversitySuzhou 234000China School of Geography and Tourism Anhui Normal UniversityWuhu 241000China

The tectonic evolution and crustal accretion process of the North Qilian Orogenic Belt(NQOB)are still under debate because of a lack of integrated constraints,especially the identifi cation of the tectonic transition from arc to initial *** we present results from zircon U-Pb geochronology,whole-rock geochemistry,and Sr-Nd-Pb isotope geochemistry of the Beidaban granites to provide crucial information for geodynamic evolution of *** U-Pb dating yields an age of 468±10 Ma for the Beidaban granites and most of the Beidaban samples contain amphibole,are potassium-rich,and have A/CNK values ranging from 0.7 to 0.9,illustrating that the Middle Ordovician Beidaban granites are K-rich,metaluminous,calc-alkaline *** geochemical characteristics indicate that the Beidaban granites are transitional I/S-type granitoids that formed in an arc *** isotopic compositions of initial(87 Sr/86 Sr)i values ranging from 0.70545 to 0.71082(0.70842 on average)andεNd(t)values ranging from−10.9 to−6.7(−8.8 on average)with two-stage Nd model ages(T DM2)of 1.74-2.08 Ga suggest that the Beidaban granites originated from Paleoproterozoic crustal *** addition,the initial Pb isotopic compositions(^(206)Pb/^(204)Pb=19.14-20.26;^(207)Pb/^(204)Pb=15.71-15.77;^(208)Pb/^(204)Pb=37.70-38.26)and geochemical features,such as high Th/Ta(17.43-30.12)and Rb/Nb(6.01-15.49)values,suggest that the Beidaban granite magma source involved recycled crustal components with igneous *** on these results in combination with previously published geochronological and geochemical data from other early Paleozoic igneous rocks,we suggest that the timing of the tectonic transition from arc to the initial collision to the fi nal closure of the North Qilian Ocean can be constrained to the Middle-Late Ordovician(ca.468–450 Ma).

关键词： Granitoids Zircon U-Pb dating Sr-Nd-Pb-isotopes Petrogenesis North Qilian Orogenic Belt

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Energy as Entanglement Witness in Bilinear-Biquadratic Spin-1 Chain

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Communications in Theoretical Physics 2006年第4X期46卷 591-594页

作者： XU Feng WANG An-Min ZHAO Ning-Bo SU xiao-qiang zhu Ren-Gui Department of Modern Physics University of Science and Technology of China Hefei 230026 China

Energy is introduced as an entanglement witness to describe the entanglement property of a quantum system. The thermal equilibrium system is guaranteed to be entangled when system is cooled down below the entanglement temperature TE. By virtue of this concept we exploit the minimum separable state energy and entanglement temperature TE of the bilinear-biquadratic antiferromagnetic spin-1 chain model. We numerically calculate TE for arbitrary values of the strength of biquadratic exchange interaction Q up to N=7. We find TE decreases with Q for fixed N when Q is between -3 and 1/3 （J = 1）. In this regime TE also decreases with N for fixed Q and varies slowly for large N. While the thermal system is always entangled when Q is smaller than -3.

关键词： entanglement witness

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The molecular biology of pancreatic adenocarcinoma:translational challenges and clinical perspectives

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Signal Transduction and Targeted Therapy 2021年第8期6卷 2348-2370页

作者： Shun Wang Yan Zheng Feng Yang Le zhu xiao-qiang zhu Zhe-Fang Wang xiao-Lin Wu Cheng-Hui Zhou Jia-Yan Yan Bei-Yuan Hu Bo Kong De-Liang Fu Christiane Bruns Yue Zhao Lun-Xiu Qin Qiong-zhu Dong Department of General Surgery Huashan HospitalCancer Metastasis InstituteFudan UniversityShanghaiChina Department of Pancreatic Surgery Pancreatic Disease InstituteHuashan HospitalFudan UniversityShanghaiChina School of Biomedical Sciences Li Ka Shing Faculty of MedicineThe University of Hong KongHong KongChina General Visceral and Cancer SurgeryUniversity Hospital of CologneCologneGermany Department of Biliary-Pancreatic Surgery Renji HospitalSchool of MedicineShanghai Jiao Tong UniversityShanghaiChina Department of Surgery Klinikum rechts der IsarSchool of MedicineTechnical University of Munich(TUM)MunichGermany Key laboratory of whole-period monitoring and precise intervention of digestive cancer Shanghai Municipal Health Commission(SMHC)ShanghaiChina

Pancreatic cancer is an increasingly common cause of cancer mortality with a tight correspondence between disease mortality and ***,it is usually diagnosed at an advanced stage with a very dismal *** to the high heterogeneity,metabolic reprogramming,and dense stromal environment associated with pancreatic cancer,patients benefit little from current conventional *** insight into the biology and genetics of pancreatic cancer has supported its molecular classification,thus expanding clinical therapeutic *** this review,we summarize how the biological features of pancreatic cancer and its metabolic reprogramming as well as the tumor microenvironment regulate its development and *** further discuss potential biomarkers for pancreatic cancer diagnosis,prediction,and surveillance based on novel liquid *** also outline recent advances in defining pancreatic cancer subtypes and subtype-specific therapeutic responses and current preclinical therapeutic ***,we discuss prospects and challenges in the clinical development of pancreatic cancer therapeutics.

关键词： clinical mortality diagnosis

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Silencing of odorant binding protein gene AlinOBP4 by RNAi induces declining electrophysiological responses of Adelphocoris lineolatus to six semiochemicals

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Insect Science 2017年第5期24卷 789-797页

作者： Xue-Ying Zhang xiao-qiang zhu Shao-Hua Gu Yan-Le Zhou Song-Ying Wang Yong-Jun Zhang Yu-Yuan Guo State Key Laboratory for Biology of Plant Diseases and Insect Pests Institute of Plant Protection Chinese Academy of AgriculturalSciences Beijing China

Odorant binding proteins （OBPs） are believed to be important for transporting semiochemicals through the aqueous sensillar lymph to the olfactory receptor cells within the insect antennal sensilla. Here, we injected AlinOBP4-siRNA into the conjunctivum between prothorax and mesothorax of the lucerne plant bug, Adelphocoris lineolatus and evaluated the silencing of AlinOBP4 by reverse transcription polymerase chain reaction （RT-PCR） analysis, quantitative real-time PCR （qPCR） test and electroantennogram （EAG） assay. The combination of RT-PCR and qPCR analyses revealed that the levels of mes- senger RNA transcript were significantly reduced ~95% in AlinOBP4-siRNA-treated A. lineolatus males and ~75% in RNAi-treated females within 48 hours. It was found that there are different EAG responses between male and female bugs when the AlinOBP4 gene was silenced by RNAi. The EAGs of A. lineolatus to two plant volatiles, tride- canal and hexyl alcohol, were reduced 9.09% and 79.45% in RNAi-treated males, 62.08% and 62.08% in RNAi-treated females compared to the controls, separately. Antennae of RNAi-treated bugs showed significantly lower electrophysiological responses to four sex pheromone analogs, butyl butanoate, 1-hexyl butyrate, （E）-2-hexenyl butyrate and hexyl hexanoate. The EAG recordings were reduced 35.43%, 35.24%, 39.96% and 78.47% in RNAi-treated males and 64.52%, 18.13%, 36.88% and 49.52% in RNAi-treated females, respectively. The results suggested that AlinOBP4 might play dual-roles in the identifi- cation of plant volatiles and sex pheromones. It was suspected that AlinOBP4 may have different functions in odor perception between male and female A. lineolatus.

关键词： Adelphocoris lineolatus electrophysiological responses odorant bindingprotein AlinOBP4 RNA interference

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食品的防霉腐包装设计

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包装工程 2007年第8期28卷 204-206页

作者：肖强李洁南昌航空大学南昌330063

食品的卫生与营养是食品包装技术要解决的问题。从食品霉腐的因素、食品包装的要求和食品的防霉腐包装设计3个方面出发,阐述了食品防霉腐包装设计的方法,希能为包装设计者提供参考。

关键词：防霉腐包装设计真空包装充气包装无菌包装

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Effects of the extrusion parameters on microstructure,texture and room temperature mechanical properties of extruded Mg-2.49Nd-1.82Gd-0.2Zn-0.2Zr alloy

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International Journal of Minerals,Metallurgy and Materials 2025年第1期32卷 136-146页

作者： Chenjin Zhang Guangyu Yang Lei xiao Zhiyong Kan Jing Guo qiang Li Wanqi Jie State Key Laboratory of Solidification Processing Northwestern Polytechnical UniversityXi’an 710072China College of Materials Science and Engineering Fuzhou UniversityFuzhou 350108China College of Chemistry and Environmental Science Qujing Normal UniversityQujing 655011China

Microstructure,texture,and mechanical properties of the extruded Mg-2.49Nd-1.82Gd-0.2Zn-0.2Zr alloy were investigated at different extrusion temperatures(260 and 320℃),extrusion ratios(10:1,15:1,and 30:1),and extrusion speeds(3 and 6 mm/s).The experimental results exhibited that the grain sizes after extrusion were much finer than that of the homogenized alloy,and the second phase showed streamline distribution along the extrusion direction(ED).With extrusion temperature increased from 260 to 320℃,the microstructure,texture,and mechanical properties of alloys changed *** dynamic recrystallization(DRX)degree and grain sizes enhanced as the extrusion ratio increased from 10:1 to 30:1,and the strength gradually decreased but elongation(EL)*** the extrusion speed increased from 3 to 6 mm/s,the grain sizes and DRX degree increased significantly,and the samples presented the typical-rare-earth(RE)*** alloy extruded at 260℃ with extrusion ratio of 10:1 and extrusion speed of 3 mm/s showed the tensile yield strength(TYS)of 213 MPa and EL of 30.6%.After quantitatively analyzing the contribution of strengthening mechanisms,it was found that the grain boundary strengthening and dislocation strengthening played major roles among strengthening *** results provide some guidelines for enlarging the industrial application of extruded Mg-RE alloy.

关键词： Mg-rare earth alloys extrusion temperature extrusion ratio extrusion speed strengthening mechanisms

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包装设计中的肌理构成

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包装工程 2006年第5期27卷 278-279页

作者：肖强詹云南昌航空工业学院南昌330063

介绍了肌理的概念和作用,并且从色彩、文字、图案、材料、造型等方面论述了肌理在包装设计中的应用。文中指出包装设计中的肌理构成从物质和精神2个层次对消费者的消费心理和行为所产生的影响。

关键词：肌理色彩文字图案造型

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现代市场营销条件下的赣文化产品包装设计探略

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包装工程 2008年第4期29卷 161-162,168页

作者：李洁肖强南昌航空大学南昌330063

从江西特色产品包装现状入手,分析了市场营销观念与现代产品包装设计的关系,进而探讨江西特色产品包装设计中融入赣文化精神的战略价值,并提出了赣文化理念融入江西特色产品包装设计中的具体措施。

关键词：包装设计市场营销赣文化

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现代元素在包装设计中的应用

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包装工程 2007年第10期28卷 221-223页

作者：肖强詹云南昌航空大学南昌330063

经济和社会的发展以及人们的消费观念决定着包装设计中构成元素的种类和形态。从数字化、时尚性、可持续性、设计的前瞻性四个方面,阐述了当今社会的现代元素在包装设计中的应用。

关键词：现代元素数字化时尚性可持续性设计的前瞻性

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The emerging role of nitric oxide in the synaptic dysfunction of vascular dementia

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Neural Regeneration Research 2025年第2期20卷 402-415页

作者： xiaorong Zhang Zhiying Chen Yinyi Xiong Qin Zhou Ling-qiang zhu Dan Liu Department of Pathology Affiliated Hospital of Jiujiang UniversityJiujiangJiangxi ProvinceChina Jiujiang Clinical Precision Medicine Research Center JiujiangJiangxi ProvinceChina Center for Cognitive Science and Transdisciplinary Studies Jiujiang UniversityJiangxi ProvinceChina Department of Neurology Affiliated Hospital of Jiujiang UniversityJiujiangJiangxi ProvinceChina Department of Rehabilitation Affiliated Hospital of Jiujiang UniversityJiujiangJiangxi ProvinceChina Department of Pathophysiology School of Basic MedicineTongji Medical CollegeHuazhong University of Science and TechnologyWuhanHubei ProvinceChina

With an increase in global aging,the number of people affected by cerebrovascular diseases is also increasing,and the incidence of vascular dementia-closely related to cerebrovascular risk-is increasing at an epidemic ***,few therapeutic options exist that can markedly improve the cognitive impairment and prognosis of vascular dementia *** in Alzheimer’s disease and other neurological disorders,synaptic dysfunction is recognized as the main reason for cognitive *** oxide is one of the ubiquitous gaseous cellular messengers involved in multiple physiological and pathological processes of the central nervous ***,nitric oxide has been implicated in regulating synaptic plasticity and plays an important role in the pathogenesis of vascular *** review introduces in detail the emerging role of nitric oxide in physiological and pathological states of vascular dementia and summarizes the diverse effects of nitric oxide on different aspects of synaptic dysfunction,neuroinflammation,oxidative stress,and blood-brain barrier dysfunction that underlie the progress of vascular ***,we propose that targeting the nitric oxide-sGC-cGMP pathway using certain specific approaches may provide a novel therapeutic strategy for vascular dementia.

关键词： endoplasmic reticulum stress endothelial nitric oxide synthase gene therapy nitric oxide NO-sGC-cGMP pathway synaptic dysfunction vascular dementia

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