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Comparison of scleral buckling using wide-angle viewing systems and indirect ophthalmoscope for rhegmatogenous retinal detachment

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International Journal of Ophthalmology(English edition) 2016年第9期9卷 1310-1314页

作者： Xiu-Juan Li xiao-peng yang xiao-Bei Lyu Department of Ophthalmology the First Affiliated Hospital of Zhengzhou University Department of Medical Equipment the First Affiliated Hospital of Zhengzhou University

AIM：To compare the effects of scleral buckling using wide-angle viewing systems（WAVS） with that using indirect ophthalmoscope for the treatment of rhegmatogenous retinal ***：The study was a retrospective analyses of the medical records of 94 eyes（94 patients） with rhegmatogenous retinal *** them,47 eyes underwent scleral buckling using WAVS with endoiiluminator（Group W）,and 47 eyes underwent scleral buckling using indirect ophthalmoscope（Group I）.Surgical durations,primary success rate,best-corrected visual acuities（BCVA）,delayed subretinal fluid absorptions and surgical complications were compared between the two ***：At baseline,there were no statistical differences between the two groups in patient＇s age（P=0.997）,gender（P=0.853）,symptom duration（P=0.216）,BCVA（P=0.389）,refractive error（P=0.167）,intraocular pressure（P=0.595）,the number of retinal breaks（P=0.832）,the extent of retinal detachment（P =0.246）,subretinal demarcation line（P=0.801）,and macular detachment（P=0.811）.The follow-up period was 12 *** surgical durations in Group W（with or without encircling buckling） were significant shorter than those in Group I（P〈0.001 respectively）.The primary success rate was94.27%in Group W,which was similar to that in Group I（92.38%,P=0.931）.The BCVA in Group W was better than that in Group I（P〈0.001） at 1-month follow-up ***,there were no significant differences between the two groups at 3-month（P=0.221）,6-month（P =0.674）,and 12-month（P=0.363） follow-up visits *** subretinal fluid absorptions were more common in Group I than in Group W at 1-month（P=0.045） follow-up visit,but there were no significant differences between the two groups at 3-month（P=0.111）,6-month（P =1.000） and 12-month follow-up visits ***：Scleral buckling using WAVS can be an alternative choose for rhegmatogenous retinal detachment

关键词： scleral buckling retinal detachment wide-angle viewing systems

Synthesis and mesomorphic properties of novel tolane-type liquid crystals

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Chinese Chemical Letters 2009年第11期20卷 1283-1286页

作者： Dong Yu Zhao Qing Yong Meng xiao peng Cui Huai yang Department of Materials Physics and Chemistry School of Materials Science and Engineering University of Science and Technology Beijing Beijing 100083 China

Two series of novel tolane-type liquid crystals （LCs） comprising of hydrogen-bonded organic acids were synthesized. The formation of dimerized H-bond LCs was confirmed by IR spectroscopy, and mesomorphic properties of the LCs were investigated by differential scanning calorimetry （DSC） and polarizing optical microscopy （POM）. It was found that the end groups of the liquid crystals as well as the unsaturated rigid core had effect on the mesomorphic properties.

关键词： Tolane Hydrogen-bonded liquid crystal Mesomorphic properties Synthesis

Relationship between glycemic variability and cognitive function in lacune patients with type 2 diabetes

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World Journal of Clinical Cases 2023年第5期11卷 1019-1030页

作者： Qi-Zhe Meng yang Wang Bing Li Zhi Xi Ming Wang Jia-Qi Xiu xiao-peng yang Department of Neurology The Second Affiliated Hospital of Zhengzhou UniversityZhengzhou 450003Henan ProvinceChina

BACKGROUND Lacunes are the manifestations of lacunar infarction which can lead many patients to the clinical outcome of disability or ***,the relationship between lacune burden,cognitive function and blood glucose fluctuation in patients with type 2 diabetes mellitus(T2DM)complicated with lacunes is not very *** To explore the correlation between glucose variability,lacune burden and cognitive function in patients with lacunes complicated with *** The clinical and imaging data of 144 patients with lacunes combined with T2DM were reviewed retrospectively.72 h continuous glucose monitoring was *** Montreal Cognitive Assessment was used to assess cognitive *** burden of lacunes was evaluated using magnetic resonance imaging *** logistic regression analysis was used to study the affecting the lacune load and cognitive impairment in *** predict the value of patients’cognitive impairment with lacunes complicated with T2DM,a receiver operating characteristic(ROC)curve and a nomogram prediction model were *** The standard deviation(SD)of the average blood glucose concentration,percentage coefficient of variation(%CV)and time of range(TIR)were significantly different between the low and the high load groups(P<0.05).The SD,%CV and TIR of the cognitive impairment group and non-cognitive impairment group were significantly different(P<0.05).SD(odds ratio(OR):3.558,95%confidence interval(CI):1.268-9.978,P=0.006),and%CV(OR:1.192,95%CI:1.081-1.315,P<0.05)were the risk factors for an increased infarct burden in lacunes patients complicated with ***(OR:0.874,95%CI:0.833-0.928,P<0.05)is a protective *** addition,an increased SD(OR:2.506,95%CI:1.008-6.23,P=0.003),%CV(OR:1.163,95%CI:1.065-1.270,P<0.05)were the risk factors for cognitive impairment in patients with lacunes complicated with T2DM,TIR(OR:0.957,95%CI:0.922-0.994,P<0.05)is a protective factor.A nomogram prediction model o

关键词： Blood glucose variability Lacunes Type 2 diabetes Cognitive impairment Nomograms

Preparation of{200}crystal faced SnO_(2) nanorods with extremely high gas sensitivity at lower temperature

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Rare Metals 2021年第8期40卷 2004-2016页

作者： Hong-Yan Xu Zheng-Run Chen Cai-Yun Liu Qin Ye xiao-peng yang Jie-Qiang Wang Bing-Qiang Cao School of Materials Science and Engineering University of JinanJinan250022China

Demand for simple and effective gas sensing sensors is growing rapidly due to the growing threat of triethylamine(TEA).Semiconductor tin oxide(SnO_(2))is one of the most widely used sensing materials for metal oxide gas *** recent years,a lot of binary ternary compound researches have been carried *** this paper,five different SnO_(2) samples were synthesized by simple synthesis method to understand the internal relationship and obtain different gas sensing *** on the low temperature nitrogen adsorption tests and the atomic arrangement model,it can be inferred that different exposed surfaces play a key role in TEA sensing *** addition,the TEA sensing activity relationship of SnO_(2) exposed crystal faces is proposed as listed:(200)>(101)>(110).

关键词： SnO_(2)gas sensor Exposed crystal faces Atomic arrangement TEA sensing properties

Effects of hepatocyte growth factor on MMP-2 expression in scleral fibroblasts from a guinea pig myopia model

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International Journal of Ophthalmology(English edition) 2014年第2期7卷 239-244页

作者： Xiu-Juan Li xiao-peng yang Guang-Ming Wan Yu-Ying Wang Jin-Song Zhang Department of Ophthalmology the First Affiliated Hospital of Zhengzhou University Department of Medical Equipment the First Affiliated Hospital of Zhengzhou University

AIMTo investigate the effects of hepatocyte growth factor (HGF) on MMP-2 expression in scleral fibroblasts from guinea pig with LIM.

关键词： myopia fibroblasts hepatocyte growth factor MMP-2 guinea pig

Posterior scleral reinforcement combined with vitrectomy for myopic foveoschisis

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International Journal of Ophthalmology(English edition) 2016年第2期9卷 258-261页

作者： Xiu-Juan Li xiao-peng yang Qiu-Ming Li Yu-Ying Wang Jing Wang xiao-Bei Lyu Heng Jia Department of Ophthalmology the First Affiliated Hospital of Zhengzhou University Department of Medical Equipment the First Affiliated Hospital of Zhengzhou University

AIM： To investigate the effects of posterior scleral reinforcement （PSR） combined with vitrectomy for myopic foveoschisis. ~ METHODS： Thirty-nine highly myopic eyes of 39 patients with myopic foveoschisis underwent PSR combined with vitrectomy. Best corrected visual acuity （BCVA）, refraction error, and the foveal thickness by optical coherence tomography （OCT） were recorded before and after the surgery, and complications were noted. RESULTS： The follow-up period was 12mo, and the main focus was on the results of the 12-month follow-up visit. The mean preoperative BCVA was 0.96±0.43 IogMAR. At the final follow-up visit, the mean BCVA was 0.46± 0.28 IogMAR, which significantly improved compared with the preoperative one （P =0.003）. The BCVA improved in 33 eyes （84.62%）, and unchanged in 6 eyes （15.38%）. At the end of follow-up, the mean refractive error was -15.13 ±2.55 D, and the improvement was significantly compared with the preoperative one （-17.53±4.51 D）（P= 0.002）. Twelve months after surgery, OCT showed complete resolution of the myopic foveoschisis and a reattachment of the fovea in 37 eyes （94.87%） and partial resolution in the remained two eyes （5.13%）. The foveal thickness was obviously reduced at 12-month follow-up visit （196.45±36.35um） compared with the preoperative one （389,32±75.56um）（P=0.002）. There were no serious complications during the 12mo follow-up period. CONCLUSION： PSR combined with vitrectomy is a safe and effective procedure for myopic foveoschisis with both visual and anatomic improvement.

关键词： high myopia myopic foveoschisis posteriorscleral reinforcement vitrectomy

Posterior scleral reinforcement for the treatment of pathological myopia

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International Journal of Ophthalmology(English edition) 2016年第4期9卷 580-584页

作者： Xiu-Juan Li xiao-peng yang Qiu-Ming Li Yu-Ying Wang Yuan Wang xiao-Bei Lyu Heng Jia Department of Ophthalmology the First Affiliated Hospital of Zhengzhou University Department of Medical Equipment the First Affiliated Hospital of Zhengzhou University Department of Ophthalmology Zhengzhou Central Hospital Affiliated to Zhengzhou University

AIM： To investigate the effects of posterior scleral reinforcement（PSR） in the treatment of pathological myopia.·METHODS： The study included 52 eyes in 43 patients with pathological myopia who underwent PSR（PSR group）, and 52 eyes in 36 age- and myopia-matched patients who did not undergo such treatment as control group. Axial length, refraction error, best corrected visual acuity（BCVA）, and macular scans by optical coherence tomography（OCT） were recorded at baseline, 6mo, 1, 3and 5y after the surgery, and the complications were noted.·RESULTS： There were no statistical differences in axial length, refractive error, or BCVA between the PSR group and the control group at baseline. At the end of the follow-up, the mean axial length was 29.79 ±1.26 mm in the PSR group, which was significantly shorter than that in the control group（30.78±1.30 mm）（P 〈0.01）, and the mean refractive error was-16.86 ±2.53 D in the PSR group, which was significantly lower than that in the control group（-19.18 ±2.12 D）（P 〈0.01）. A statistically significant difference in BCVA was found between the PSR group（0.51 ±0.25 log MAR） and the control group（0.62±0.26 log MAR） at the postoperative 5-year follow-up（P 〈0.01）. There were no serious complications during the 5-year follow-up period.·CONCLUSION： PSR can prevent axial elongation and myopia progression in eyes with pathological myopia.

关键词： pathological myopia posterior scleral reinforcement axial length

Flanibizumab Plus Combined Surgery for Treatment o Neovascular Glaucoma with Vitreous Hemorrhage

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Chinese Medical Journal 2015年第15期128卷 2078-2083页

作者： Xiu-Juan Li xiao-peng yang Qiu-Ming Li Yu-Ying Wang xiao-Bei Lyu Department of Ophthalmology The First Affiliated Hospital of Zhengzhou University Zhengzhou Henan 450052 China Department of Medical Equipment The First Affiliated Hospital of Zhengzhou University Zhengzhou Henan 450052 China

Background：Neovascular glaucoma （NVG） is a refractory *** management of NVG is very difficult,and it is more difficult when combined with vitreous *** aim of this study was to investigate the effects of ranibizumab plus combined surgery for NVG with vitreous ***：A total of 26 eyes of 26 NVG patients with vitreous hemorrhage were recruited in this *** patients aged from 36 to 63 years with a mean age of 51.97 ± 7.60 *** mean intraocular pressure （IOP） was 46.38 ± 5.75 mmHg （1 mmHg =0.133 kPa） while being treated with the maximum medical *** mean best-corrected visual acuities converted to logarithm of the minimum angle of resolution （logMAR BCVA） was 2.62 ± *** the patients underwent intravitreal injection of 0.5 mg （0.05 ml） ranibizumab combined with pars plana vitrectomy （PPV）,pars plana lensectomy （PPL） with a preserved anterior capsule,panretinal photocoagulation （PRP）,and trabeculectomy （intravitreal ranibizumab [IVR] ＋ PPV ＋ PPL ＋ PRP ＋ trabeculectomy）.The IOP and logMAR BCVA were the main outcome measures in this ***：The follow-up period was 12 *** mean postoperative IOPs were 26.38 ± 3.75 mmHg,21.36 ± 3.32 mmHg,1 8.57 ± 3.21 mmHg,and 16.68 ± 2.96 mmHg,respectively at 7 days,1 month,3 months,and 12 months after PPV ＋ PPL ＋ PRP ＋ *** the last follow-up,the mean IOP was significantly lower than the preoperative one （t =6.612,P =0.001）.At 7 days,1 month,3 months,and 12 months after PPV ＋ PPL ＋ PRP ＋ trabeculectomy,the mean logMAR BCVA were 1.30 ± 0.36,1.29 ± 0.37,1.29 ± 0.39,and 1.26 ± 0.29,*** the last follow-up,the mean logMAR BCVA was significantly improved,and the difference was statistically significant compared with preoperative one （t =6.133,P =0.002）.The logMAR BCVA improved in 22 eyes （84.62%）,and remained stable in 4 eyes （15.38%）.The neovascularization in the iris and the angle regressed significantly in all patients 7 days after ranibizumab injection

关键词： Neovascular Glaucoma Panretinal Photocoagulation Pars Plana Vitrectomy Ranibizumab Trabeculectomy

Comparison of biological characteristics of marrow mesenchymal stem cells in hepatitis B patients and normal adults

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World Journal of Gastroenterology 2007年第11期13卷 1743-1746页

作者： Liang peng Hua Li Lin Gu xiao-Mou peng yang-Su Huang Zhi-Liang Gao Department of Infectious Diseases The Third Affiliated Hospital of Sun Yat-Sen University Guangzhou 510630 Guangdong Province China

AIM: To establish a culture system of marrow mesenchymal stem cells (MSCs)from hepatitis B patients and normal adults and to compare their biological characteristics. METHODS: MSCs were isolated from bone marrow in 34 male hepatitis B patients and 15 male normal adults and cultivated in vitro. Their biological characteristics including surface markers, shapes and appearances, growth curves, first passage time and passage generations were compared. RESULTS: Cultivation achievement ratio of hepatitis B patients was lower than that of normal adults, no statistical significance (82.35% vs 100%, P > 0.05). Compared with MSCs of normal adults, MSCs of hepatitis B patients presented a statistical lower growth curve, longer first passage time (13.0 ± 1.6 d vs 11.4 ± 1.5 d, P < 0.05), fewer passaging generation numbers (10.5 ± 1.4 generations vs 12.3 ± 1.7 generations, P < 0.05), though both shared same appearances, shapes and surface markers. MSCs in hepatitis B patients would expand, spread out and age more easily and there were more refractive particles in the cytoplasm. CONCLUSION: MSCs from hepatitis B patients can be cultured in vitro. Although their appearance, shape and surface marker are similar to those of MSCs from normal adults, there are differences in their biological characteristics.

关键词： Marrow mesenchymal stem cells Culture in vitro Biological characters